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Computer Modeling in Engineering & Sciences 2023年第8期136卷 1371-1397页

作者： rafael marin ferro Renato Pavanello Coordination of Mechanical Engineering Federal Institute of Science and Technology of ES-IFESAracruz-ES29192-733Brazil Department of Computational Mechanics Faculty of Mechanical EngineeringUnicampCampinas-SP13083-860Brazil

This work analyzes the implementation of a continuous method of structural topology optimization(STO)using open-source software for all stages of the topology optimization problem:modeling,sensitivity analysis and *** implementation involves three main components:numerical analysis using the Finite Element Method(FEM),sensitivity analysis using an Adjoint method and an optimization *** order to allow the automated numerical solution of Partial Differential Equations(PDEs)and perform a sensitivity analysis,FEniCS and Dolfin Adjoint software are used as tools,which are open-source *** the optimization process,Ipopt(Interior Point OPTimizer)is used,which is a software package for nonlinear optimization scale designed to find(local)solutions of mathematical optimization *** topological optimization method used is based on the SIMP-Solid IsotropicMaterial with Penalization *** considered problem is the minimization of compliance/maximization of stiffness,considering the examples of recurrent structures in the literature in 2D and 3D.A density filtering algorithm based on Helmholtz formulation is *** complete code involves 51 lines of programming and is presented and commented in detail in this article.

关键词： Structural topology optimization finite element method FEniCS Dolfin Adjoint

MEC-based architecture for interoperable and trustworthy internet of moving things

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Digital Communications and Networks 2023年第1期9卷 270-279页

作者： Jesus Sanchez-Gomez rafael marin-Perez Ramon Sanchez-Iborra Miguel Angel Zamora Department of Information and Communications Engineering University of MurciaMurciaSpain Odin Solutions S.L. MurciaSpain University Center of Defense San Javier Air Force BaseMurciaSpain

The expansion of the Internet of Moving Things(IoMT)leads to limitless and continuous working playgrounds exploited by highly dynamic end *** requires the adoption of multi-Radio Access Technologies(RATs)-based strategies to provide IoMT units with ubiquitous *** this end,the development of secure bootstrapping and authentication mechanisms is necessary to permit the secure operation of end *** the transmission and power limitations of these elements,current cryptographic solutions do not address these stringent *** that reason,in the study we present a Multi-Access Edge Computing(MEC)-based endto-end architecture that enables an efficient and secure authentication and key agreement between end devices and network servers over heterogeneous resource-limited networks such as the Low Power Wide Area Networks(LPWANs).Our proposal is based on the Authentication,Authorization,and Accounting(AAA)architecture and the recent Internet Engineering Task Force initiatives Static Context Header Compression and Low-Overhead *** results obtained from experimental tests reveal the validity of the proposal as it enables constrained IoMT devices to gain IPv6 connectivity as well as performs end-to-end secure authentication with notable reliability and controlled latency.

关键词： Internet of moving things LPWAN Authentication LO-CoAP-EAP SCHC

Low-cost disordered carbons for Li/S batteries： A high- performance carbon with dual porosity derived from cherry pits

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Nano Research 2018年第1期11卷 89-100页

作者： Celia Hernandez-Rentero rafael Cordoba Noelia Moreno Alvaro Caballero Julian Morales Mara Olivares-marin Vicente Gomez-Serrano Dpto. Ouimica Inorgdnica e Ingenierfa Quimica Instituto de Quimica Fina y Nanoqufmica Universidad de C6rdoba 14071 C6rdoba Spain Dpto. Quimica Inorg6nica Facultad de Ciencias Universidad de Extremadura 06006 Badajoz Spain

A micro- and mesoporous carbon obtained from cherry pit waste and activated with HBPO4 acid has been studied as the sulfur host for Li/S batteries. The carbon has a high specific surface area of 1,662 m2·g-1 （SBET） and micropore and mesopore volumes of 0.57 and 0.40 cm3·g-1, respectively. The S/C composite, with a sulfur content of 57% deposited by the disproportionate reaction of a SaO2- solution in an acid medium without an additional heating step above the S melting point, delivers an initial specific capacity of 1,148 mah·g-1 at a current of C/16. It also has a high capacity retention of 915 mAh·g-1 after 100 cycles and a Coulombic efficiency close to 100%. The good performance of the composite was also observed under higher current rates and long-term cycling tests. The capacities delivered by the cell after 200 cycles were 707 and 410 mAh·g-1 at C/2 and 1C （1C = 1,675 mA·g-1）, respectively, maintaining the high Coulombic efficiency. The overall electrochemical response of this carbon as the sulfur matrix is among the best reported so far among the other biomass-derived carbons, probably because of the micro- and mesopore system formed upon activation.

关键词： activated carbon agricultural waste cherry stone sulfur composite lithium-sulfur batteries

Real World Evidence (RWE, Real World Data), of the Effectiveness of Amoxicillin-Clavulanate in the Treatment of Children with Upper Respiratory Tract Infections (Tonsillitis, Otitis, Sinusitis)

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Open Journal of Respiratory Diseases 2024年第3期14卷 77-89页

作者： Maria Gonzalez Yibirin Juan Chirinos David Alberto Rincón Matute Trinidad Coll Miriam Rosales Yuliana Guevara Kuanlin Doried Guitens Pérez Mauribel Figueroa Rosalía Romero Jurgensen Andrea Rojas Gabriel Jesús Arismendi González Milagros Salcedo Marife Martina marin Marcano Carolina Mendoza Marycarmen Anuel Maria Morao Raymond Aguilera Diego Ríos Maryenis Rodríguez Loren Sánchez Jennyfer Fernández rafael González Zaidith Zerpa Nelson Rodríguez Mirluis Rojas Sixtaime Quijada Mariangel Moya Diego Orsini Chris Gómez Hector Gamero José Rodríguez Laboratorios LETI S.A.V. Guarenas Venezuela Ambulatorio Rural tipo II CPT3 Pampatar Venezuela Ambulatorio Los Robles CPT Dr. Luis Rosas Bravo Los Robles Venezuela Clnica Prevaler Pampatar Venezuela Hospital tipo 1 Dr. David Espinoza Rojas en Salamanca Salamanca Venezuela Centro Mdico Rotary El Valle Venezuela Ambulatorio Rural Tipo II CPT3 Dr. Enrique Albornoz Lares La Asuncin Venezuela

Real-world evidence (RWE) is clinical evidence on a medical product’s safety and efficacy that is generated using real-world data (RWD) resulting from routine healthcare delivery. This study evaluates the clinical efficacy of amoxicillin + clavulanic acid in children with pharyngitis, acute otitis, or acute rhinosinusitis with suspected bacterial origin under normal office and home conditions. Methods: This was a real-life, prospective, observational, pharmacovigilance study. It included children of both sexes between 2 and 12 years old, with a diagnosis of Rhinopharyngitis (tonsillitis), Acute Otitis Media and Rhinosinusitis. The main effectiveness variable evaluated was reduction and time to resolution of symptoms. All patients received Amoxicillin/Clavulanic Acid suspension 600 mg/42.9 mg/5 mL at a dose of 90 mg/Kg/day in two doses, every 12 hours for 7 days. The evaluations were carried out at the beginning, at 72 hours (3rd day) and at 7 days. All patients underwent culture and antibiogram. Results: The majority of cultures were negative for pathogenic germs, suspecting unidentifiable germs, or viral etiology despite the rigorous selection of subjects following validated scores. The most frequently isolated germ was Staphylococcus aureus;growth of gram-negative bacteria was reported in 33.33% of the cultures. There was a significant improvement in symptoms in children with tonsillitis and rhinosinusitis from the first 72 hours of treatment, persisting until the 7 days. In the otitis media group, returning to normal by the tenth day. During the conduction of this investigation, no adverse effects associated with the prescribed therapy were reported.

关键词： Amoxicillin Clavulanic Acid Tonsillitis Otitis Sinusitis

Ivermectin Efficacy against Triatoma infestans in vivo Using Hen Model

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Journal of Pharmacy and Pharmacology 2014年第6期2卷 353-358页

作者： Martin Miguel Dade Martin rafael Daniele Gustavo Horacio marin Maria Pia Silvestrini Nora Mestorino Department of Pharmacology Faculty of Medicine Sciences National University of La Plata La Plata 1900 Buenos Aires Argentina Laboratory of Pharmacological and Toxicological Studies Faculty of Veterinary Sciences National University of La Plata La Plata 1900 Buenos Aires Argentina Biostatistic Department Faculty of Veterinary Sciences National University of La Plata La Plata 1900 Buenos Aires Argentina

Chagas disease is endemic in south America. One of the major preventive actions is removing the vector TI （Triatoma infestans） from household. Although households are frequently sprayed to eliminate TI, pets and domestic animals are natural storage for vector survival. This work proposes TI elimination from farm animals using IVM （ivermectin）, as a new strategy to Chagas disease control. Rhode island hens were divided into TG （treatment groups） and CG （control groups）. TG received IVM while CG received DMSO. TI used in the assay was fifth instar nymphs. Hens served as food source for TI. Blood was extracted for IVM chromatographic pharmacokinetic analysis. The pharmacokinetic models that best fitted the IVM plasma profiles were determined by means of the minimum Akaike information criterion estimation （MAICE） test. In TG nymphs mortality was 23.25% to 47.5% at 24-120 h, respectively. IVM plasma profile showed a first-order one-compartment model with a rapid absorption reaching a Cmax （maximum concentration） of 64.7 ± 15.4 ng/mL at 48 h （Troop） post-application. Our data shows that TI mortality is directly related to the plasma concentration of IVM and is up to 47.5% at 120 h. Therefore, ivermectin may have a potential effect on controlling TI vector in peri-domestic level.

关键词： Chagas control ivermectin Triatoma infestans.

Sustainability Assessment of Alternatives for Heat Generation and Transfer in Saunas

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Journal of Environmental Protection 2015年第12期6卷 1378-1393页

作者： Nora Munguia Luis Velazquez rafael Perez Daniel Rincón Martha marin Biagio F. Giannetti Cecília M. V. B. Almeida Feni Agostinho Sustainability Graduate Program Industrial Engineering Department University of Sonora (UNISON) Hermosillo Mexico Work Environment Department University of Massachusetts Lowell Lowell MA USA Production Engineering Graduate Program Paulista University (UNIP) S&#227 o Paulo Brazil

In the search for renewable energy sources, solar energy appears, among others, as a powerful alternative;mainly for those countries located at Earth’s equatorial region. This is the case of a Fresnel device that uses solar radiation to warm-up the air;for instance, within saunas. Authors coined the term sustainable technological innovation to refer to a technological innovation in accordance to the principles of sustainability. The object of this research was comparing the sustainability of a Fresnel Lens Solar Concentration (FLSC) against the sustainability of other twelve alternatives to generate heat. This article assesses the sustainability of fourteen technological options for heat generation and transfer to saunas in the northwest region of Mexico where temperatures often reach above 45 C and where there is a greater potential for exploiting solar energy. Emergy accounting, economic analysis, and global warming potential are the three indicators considered in quantifying sustainability. Results show that infrared ceramic photovoltaic, infrared carbon photovoltaic and infrared metal photovoltaic are the most sustainable systems. The Fresnel device reached the fourth and tenth position, using electricity from photovoltaic and from grid respectively, among all fourteen assessed devices, respectively. Although Fresnel equipment does not release any global warming gases into the atmosphere, or even it demands low amount of non-renewable resources, 1.40 and 4.47 E17 seJF/yr. it requires high economic investment, 20,800 and 79,600 USD/yr, for the implementation and operation phases, which decrease its sustainability performance compared to twelve other evaluated devices.

关键词： emergy heat generation and transfer sustainable technology innovation saunas

Is there a place for cellular therapy in depression?

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World Journal of Psychiatry 2021年第9期11卷 553-567页

作者： Pedro Antonio Schmidt do Prado-Lima Zaquer Suzana Munhoz Costa-ferro Bruno Solano de Freitas Souza Ivana Beatrice Manica da Cruz Biogenomics Lab Brain Institute of Rio Grande do Sul(BraIns) Pontifical Catholic University of Rio Grande do SulPorto Alegre 90610-000Rio Grande do SulBrazil Center for Biotechnology and Cell Therapy Sao Rafael HospitalSalvador 41253-190BahiaBrazil D’Or Institute for Research and Education(IDOR) Salvador 41253-190BahiaBrazil Laboratory of Tissue Engineering and Immunopharmacology Gonçalo Moniz InstituteFiocruzSalvador 40296-710BahiaBrazil Health Sciences Center Federal University of Santa MariaSanta Maria 97105900RSBrazil

Although efforts have been made to improve the pharmacological treatment of depression,approximately one-third of patients with depression do not respond to conventional therapy using *** potential non-pharmacological therapies have been studied in the last years,including the use of mesenchymal stem cell therapies to treat *** therapies are reviewed here since it is clinically relevant to develop innovative therapeutics to treat psychiatric *** data corroborate that mesenchymal stem cell therapy could be considered a potential treatment for depression based on its antiinflammatory and neurotrophic ***,some clinical trials involving treatment of depression with stem cells are in progress,but with no published *** studies and other future clinical investigations will be crucial to define how much mesenchymal stem cells can effectively be used in psychiatric clinics as a strategy for supporting depression treatment.

关键词： Mood disorders Stem cells transplant Mesenchymal stem-cells transplant Inflammation Immunomodulation Depression

Correlation between therapy and lipid profile of leprosy patients:is there a higher risk for developing cardiovascular diseases after treatment?

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Infectious Diseases of Poverty 2017年第1期6卷 721-727页

作者： Rosalba V.G.Silva rafael Sde Araujo Tinara L.S.Aarao Paulo Diovanne da Silva Costa Jorge R.Sousa Juarez A.S.Quaresma Bettina ferro de Souza Hospital Federal do Para UniversityBelemParaBrazil Center of Health and Biological Science Para State UniversityBelemParaBrazil Tropical Medicine Center Federal do Para UniversityAv.Generalissimo Deodoro 92UmarizalBelemPara66055-190Brazil

Background:The impact of leprosy reduces health-related quality of life of affected patients,interfering with different factors such as *** study investigated the lipid profile,nutritional status,and risk for cardiovascular disease(CVD)in patients who underwent leprosy treatment in ***:Eighty-four adult patients of both genders ranging in age from 20 to 60 years and diagnosed with paucibacillary(PB)or multibacillary(MB)leprosy were selected after undergoing multidrug *** following data were collected:sociodemographic and clinical data;food intake;anthropometric measures(weight,height,and waist circumference);and lipid profile components(total cholesterol,high-density lipoprotein cholesterol[HDL-c],low-density lipoprotein cholesterol[LDL-c],and triglycerides).Results:Among the study population,there was a predominance of males(65.48%)aged 50 to 60 years,patients with an income of 248-496 American dollars(63.10%),patients who completed elementary school(65.48%),inactive patients(76.19%),non-smokers(46.43%),and non-drinking patients(69.05%).The levels(mean±standard deviation)of total cholesterol were 193.8±29.4 mg/dL in the PB form and 203.5±41.7 mg/dL in the MB *** mean LDL-c was 116.9±22.7 mg/dL in PB patients and 121±31.3 mg/dL in MB *** triglyceride levels were 123.4±45.2 mg/dL in the PB form and 147.4±88.9 mg/dL in the MB *** evaluation of nutritional status showed that 41.67%of the patients were eutrophic,while 55.96%had excess *** intake was significantly associated with HDL-c in male patients(P=0.0264)and with triglycerides in patients above the ideal weight(P=0.0049).Conclusions:The risk of acquiring CVDs was observed to be high due to patients’excess weight and increased waist *** study will guide clinicians in the adequate treatment of patients with leprosy in order to avoid adverse cardiovascular events.

关键词： Leprosy Post-leprosy treatment Nutritional status Total cholesterol Triglycerides Cardiovascular disease Brazil

Search for the doubly heavy baryons Ωbc0 and Ξbc0 decaying to Λc+π- and Ξc+π-

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Chinese Physics C 2021年第9期45卷 14-25页

作者： R.Aaij C.Abellán Beteta T.Ackernley B.Adeva M.Adinolfi H.Afsharnia C.A.Aidala S.Aiola Z.Ajaltouni S.Akar J.Albrecht F.Alessio M.Alexander A.Alfonso Albero Z.Aliouche G.Alkhazov P.Alvarez Cartelle S.Amato Y.Amhis L.An L.Anderlini A.Andreianov M.Andreotti F.Archilli A.Artamonov M.Artuso K.Arzymatov E.Aslanides M.Atzeni B.Audurier S.Bachmann M.Bachmayer J.J.Back P.Baladron Rodriguez V.Balagura W.Baldini J.Baptista Leite R.J.Barlow S.Barsuk W.Barter M.Bartolini F.Baryshnikov J.M.Basels G.Bassi B.Batsukh A.Battig A.Bay M.Becker F.Bedeschi I.Bediaga A.Beiter V.Belavin S.Belin V.Bellee K.Belous I.Belov I.Belyaev G.Bencivenni E.Ben-Haim A.Berezhnoy *** D.Berninghoff H.C.Bernstein C.Bertella A.Bertolin C.Betancourt F.Betti Ia.Bezshyiko S.Bhasin J.Bhom L.Bian M.S.Bieker S.Bifani P.Billoir M.Birch F.C.R.Bishop A.Bitadze A.Bizzeti M.Bj?rn M.P.Blago T.Blake F.Blanc S.Blusk D.Bobulska J.A.Boelhauve O.Boente Garcia T.Boettcher A.Boldyrev A.Bondar N.Bondar S.Borghi M.Borisyak M.Borsato J.T.Borsuk S.A.Bouchiba T.J.V.Bowcock A.Boyer C.Bozzi M.J.Bradley S.Braun A.Brea Rodriguez M.Brodski J.Brodzicka A.Brossa Gonzalo D.Brundu A.Buonaura C.Burr A.Bursche A.Butkevich J.S.Butter J.Buytaert W.Byczynski S.Cadeddu H.Cai R.Calabrese L.Calefice L.Calero Diaz S.Cali R.Calladine M.Calvi M.Calvo Gomez P.Camargo Magalhaes A.Camboni P.Campana A.F.Campoverde Quezada S.Capelli L.Capriotti A.Carbone G.Carboni R.Cardinale A.Cardini I.Carli P.Carniti L.Carus K.Carvalho Akiba A.Casais Vidal G.Casse M.Cattaneo G.Cavallero S.Celani J.Cerasoli A.J.Chadwick M.G.Chapman M.Charles Ph.Charpentier G.Chatzikonstantinidis C.A.Chavez Barajas M.Chefdeville C.Chen S.Chen A.Chernov V.Chobanova S.Cholak M.Chrzaszcz A.Chubykin V.Chulikov P.Ciambrone M.F.Cicala X.Cid Vidal G.Ciezarek P.E.L.Clarke M.Clemencic H.V.Cliff J.Closier J.L.Cobbledick V.Coco J.A.B.Coelho J.Cogan E.Cogneras L.Cojocariu P.Collins T.Colombo L.Congedo A.Contu N.Cooke G.Coombs G.Corti C.M.Costa Sobral B.Couturier D.C.Craik J.Crkovská M.Cruz Torres R.Currie C.L.Da Silva E.Dall'Occo J.Dalseno C.D'Amb University of Edinburgh Horia Hulubei National Institute of Physics and Nuclear Engineering INFN Sezione di Bari Università di Bari Los Alamos National Laboratory (LANL) Van Swinderen Institute University of Groningen Universiteit Maastricht AGH-University of Science and Technology Faculty of Physics and Applied Computer Science Université Clermont Auvergne Università di Cagliari Institute for Nuclear Research of the National Academy of Sciences (KINR) School of Physics University College Dublin NSC Kharkiv Institute of Physics and Technology (NSC KIPT) INFN Sezione di Perugia STFC Rutherford Appleton Laboratory School of Physics and Astronomy Monash University Novosibirsk State University CNRS/IN2P3 Department of Physics and Astronomy Uppsala University Università di Genova School of Physics State Key Laboratory of Nuclear Physics and Technology Peking University National Center for Nuclear Research (NCBJ) Università di Roma Tor Vergata Pontifícia Universidade Católica do Rio de Janeiro (PUC-Rio) Universidade Federal do Triangulo Mineiro (UFTM) Institute of Particle Physics LPC Central China Normal University Hangzhou Institute for Advanced Study UCAS Instituto de Fisica Corpuscular Centro Mixto Universidad de Valencia-CSIC Nikhef National Institute for Subatomic Physics and VU University Amsterdam National Research Tomsk Polytechnic University AGH-University of Science and Technology Faculty of Computer Science Electronics and Telecommunications University of Michigan Università di Siena Università di Padova Scuola Normale Superiore National Research Centre Kurchatov Institute Università degli Studi di Milano MSU-Iligan Institute of Technology (MSU-IIT) Università di Firenze INFN Sezione di Roma La Sapienza Institut für Physik Universit?t Rostock INFN Sezione di Milano Departamento de Fisica Universidad Nacional de Colombia Universit?t Bonn-Helmholtz-Institut für Strahlen und Kernphysik Hanoi University of Science Università di Pisa P.N. Lebedev Physical Institute Russian Academy of Science (LPI RAS) Università

The first search for the doubly heavy Ωbc0baryon and a search for the Ξbc0baryon are performed using pp collision data collected via the LHCb experiment from 2016 to 2018 at a centre-of-mass energy of 13 TeV,corresponding to an integrated luminosity of 5.2 *** baryons are reconstructed via their decays to ∧c+π-andΞc+π-.No significant excess is found for invariant masses between 6700 and 7300 MeV/c2,in a rapidity range from2.0 to 4.5 and a transverse momentum range from 2 to 20 MeV/*** limits are set on the ratio of the Ωbc0andΞbc0production cross-section times the branching fraction to ∧c+π-（Ξc+π-） relative to that of the ∧b0（Ξb0） baryon,for different lifetime hypotheses,at 95% confidence *** upper limits range from 0.5×10-4to 2.5×10-4for theΩbc0→∧c+π-(Ξbc0→∧c+π-) decay,and from 1.4×10-3to 6.9×10-3for the Ωbc0→Ξc+π-(Ξbc0→Ξc+π-) decay,depending on the considered mass and lifetime of the Ωbc0(Ξbc0) baryon.

关键词： B physics quarkonium spectroscopy heavy quark production

Search for the rare decay B^(0)→J/ψФ

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Chinese Physics C 2021年第4期45卷 47-60页

作者： R.Aaij C.Abellin Beteta T.Ackernley B.Adeva M.Adinolfi H.Afsharnial C.A.Aidala S.Aiola Z.Ajaltouni S.Akar J.Albrecht F.Alessio M.Alexander A.Alfonso Albero Z.Aliouche G.Alkhazov P.Alvarez Cartelle S.Amato Y.Amhis L.An L.Anderlini A.Andreianov M.Andreotti F.Archilli A.Artamonov M.Artuso K.Arzymatov E.Aslanides M.Atzeni B.Audurier S.Bachmann M.Bachmaver J.J.Back S.Baker P.Baladron Rodriguez V.Balagura W.Baldinit J.Baptista Leite R.J.Barlow S.Barsuk W.Barter M.Bartolini F.Baryshnikov J.M.Basels G.Bassi B.Batsukh A.Battig A.Bay M.Becker F.Bedeschis I.Bediaga A.Beiter V.Belavin S.Belin V.Bellee K.Belous I.Belov I.Belyaev G.Bencivenni E.Ben-Haim A.Berezhnoy *** D.Berninghoff H.C.Bernstein C.Bertella E.Bertholet A.Bertolin C.Betancourt F.Betti M.O.Bettler Ia.Bezshyiko S.Bhasin J.Bhom L.Bian M.S.Bieker S.Bifani P.Billoir M.Birch F.C.R.Bishop A.Bizzeti M.Biorn M.P.Blago T.Blake F.Blanc S.Blusk D.Bobulska J.A.Boelhauve O.Boente Garcia T.Boettcher A.Boldyrev A.Bondar N.Bondar S.Borghi M.Borisyak M.Borsato J.T.Borsuk S.A.Bouchiba T.J.V.Bowcock A.Boyer C.Bozzi M.J.Bradley S.Braun A.Brea Rodriguezs M.Brodski J.Brodzicka A.Brossa Gonzalo D.Brundu A.Buonaura C.Burr A.Burschee A.Butkevich J.S.Butter J.Buytaert W.Byczynski S.Cadeddu H.Cai R.Calabrese L.Calefice L.Calero Diaz S.Cali R.Calladine M.Calvi M.Calvo Gomez P.Camargo Magalhaes A.Camboni P.Campana D.H.Campora Perez A.F.Campoverde Quezada S.Capelli L.Capriotti A.Carbonel G.Carboni R.Cardinale A.Cardini I.Carli P.Carniti L.Carus K.Carvalho Akiba A.Casais Vidal G.Casse M.Cattaneo G.Cavallero S.Celani J.Cerasoli A.J.Chadwick M.G.Chapman M.Charles Ph.Charpentier G.Chatzikonstantinidis C.A.Chavez Barajas M.Chefdeville C.Chen S.Chen A.Chernov S.-G.Chitic V.Chobanova S.Cholak M.Chrzaszcz A.Chubykin V.Chulikov P.Ciambrone M.F.Cicala X.Cid Vidal G.Ciezarek P.E.L.Clarke M.Clemencic H.V.Cliff J.Closier J.L.Cobbledick V.Coco J.A.B.Coelho J.Cogan E.Cogneras L.Cojocariu P.Collins T.Colombo L.Congedo A.Contu N.Cooke G.Coombs G.Corti C.M.Costa Sobral B.Couturier D.C.Craik J.Crkovska M.Cruz Centro Brasileiro de Pesquisas Fisicas(CBPF) Riode JaneiroBrazil Universidade Federal do Riode Janeiro(UFRJ) Riode JaneiroBrazil Center for High Energy Physics Tsinghua UniversityBeijingChina School of Physics State Key Laboratory of Nuclear Physics and Technology Peking UniversityBeijingChina University of Chinese Academy of Sciences BeijingChina Institute Of High Energy Physics(IHEP) BejingChina Institute of Particle Physics Central China Normal UniversityWuhanHubeiChina Univ.Grenoble Alpes Univ.Savoie Mont BlancCNRSIN2P3-LAPPAnnecyFrance Universite Clermont Auvergne CNRS/IN2P3LPCClermont-FerrandFrance Aix Marseille Univ CNRS/IN2P3CPPMMarseilleFrance Universitq Paris-Saclay CNRS/IN2P3IJCLabOrsayFrance LPNHE Sorbonne UniversiteParis Diderot Sorbonne Paris CiteCNRS/IN2P3ParisFrance I.Physikalisches Institut RWTH Aachen UniversityAachenGermany Fakultat Physik Technische Universitat DortmundDortmundGermany Max-Planck-Institut fir Kernphysik(MPIK) HeidelbergGermany Physikalisches Institut Ruprecht-Karls-Universitat HeidelbergHeidelbergGermany School of Physics University College DublinDublinIreland INFN Sezione di Bari BariItaly INFN Sezione di Bologna BolognaItaly INFN Sezione di Ferrara FerraraItaly INFN Sezione di Firenze FirenzeItaly INFN Laboratori Nazionali di Frascati Frascatiltaly INFN Sezione di Genova GenovaItaly INFN Sezione di Milano Bicocca Milanolaly INFN Sezione di Milano MilanoItaly INFN Sezione di Cagliari Monserratoltaly Universita degli Studi di Padova Universita e INFNPadovaPadovaItaly INFN Sezione di Pisa PisaItaly INFN Sezione di Roma Tor Vergata RomaItaly INFN Sezione di Roma La Sapienza RomaItaly Nikhef National Institute for Subatomic Physics AmsterdamNetherlands Nikhef National Institute for Subatomic Physics and VU University Amsterdam AmsterdamNetherlands Henryk Niewodniczanski Institute of Nuclear Physics Polish Academy of Sciences KrakowPoland AGH-University of Science and Technology Faculty of Physics and Applied Computer Science

A search for the rare decay B^(0)→J/ψФis performed using Pp collision data collected with the LHCb dete-ctor at centre-of-mass energies of 7,8 and 13 TeV,corresponding to an integrated luminosity of9 *** significant signal of the decay is observed and an upper limitof 1.1x 10^(-7)at 90%confidence level is set on the branching fraction.

关键词： B physics flavour physics rare decay ω-Фmixing branching fraction