检索结果-南通市图书馆

Augmented reality assisted surgery： a urologic training tool

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Asian Journal of Andrology 2016年第5期18卷 732-734页

作者： Ryan M Dickey neel Srikishen Larry i Lipshultz Philippe E Spiess rafael E Carrion Tariq S Hakky Scott Department of Urology Baylor College of Medicine Houston 77030 USA University of South Florida Department of Urology Tampa 33606 USA.

Augmented reality is widely used in aeronautics and is a developing concept within surgery. in this pilot study, we developed an application for use on Google Glass optical head-mounted display to train urology residents in how to place an inflatable penile prosthesis. We use the phrase Augmented Reality Assisted Surgery to describe this novel application of augmented reality in the setting of surgery. The application demonstrates the steps of the surgical procedure of inflatable penile prosthesis placement. it also contains software that allows for detection of interest points using a camera feed from the optical head-mounted display to enable faculty to interact with residents during placement of the penile prosthesis. Urology trainees and faculty who volunteered to take part in the study were given time to experience the technology in the operative or perioperative setting and asked to complete a feedback survey. From 30 total participants using a lO-point scale, educational usefulness was rated 8.6, ease of navigation was rated 7.6, likelihood to use was rated 7.4, and distraction in operating room was rated 4.9. When stratified between trainees and faculty, trainees found the technology more educationally useful, and less distracting. Overall, 81% of the participants want this technology in their residency program, and 93% see this technology in the operating room in the future. Further development of this technology is warranted before full release, and further studies are necessary to better characterize the effectiveness of Augmented Reality Assisted Surgery in urologic surgical training.

关键词： andrology augmented reality assisted surgery Google glass inflatable penile prosthesis optical head mounted display surgical education

Altered histone retention and epigenetic modifications in the sperm of infertile men

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Asian Journal of Andrology 2012年第2期14卷 239-240页

作者： rafael Oliva Josep Luis Ballesca Genetics Unit Department of Physiological Sciences I University of Barcelona Biochemistry and Molecular Genetics Service and Andrology Unit Hospital Clinic 08036 Barcelona Spain

it is well know that the nuclei of spermatogenic cells experience one of the most extremely marked chromatin changes known in cells. At the end of spermatogenesis, the histones are removed in many species and the DnA ... 详细信息

关键词： Sustainability Environmental sciences Biogeography Biogeochemistry

Timing of surgery in Crohn’s disease: A key issue in the management

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2008年第36期14卷 5532-5539页

作者： rafael Alós Joaquín Hinojosa Servicio de Cirugía General Unidad de Coloproctología Hospital de Sagunto Valencia Spain Unidad de Digestivo Servicio de Medicina Interna Hospital de Sagunto Valencia Spain

The timing of the decision for operation in Crohn’s disease is based on an evaluation of the several factors such as the failure of medical treatment, complications due to the Crohn’s disease or to the farmacological therapy, development of dysplasia or cancer and growth retardation. A complete evaluation of these factors should result in operation timed to the patient’s best advantage, achieving maximal relief of symptoms with improvement of quality of life. Given the complexity and heterogeneity of the disease and the different options for treatment, is difficult to systematize when the optimal moment for the surgery is arrived. A very important factor in the management of Crohn’s disease is the multidisciplinary approach and the patient preference should be a significant factor in determining the choice of therapy. The surgery should be considered such another option in the sequential treatment of Crohn’s disease. We have analyzed the factors that are involved in the decision taking of the surgical treatment regarding to the experience and the published literature. When did the medical therapy fail? when is the appropriate moment to operate on the patient? Or which complications of Crohn’s disease need a surgery? These are some of the questions we will try to answer.

关键词： Crohn's disease Surgical treatment Medical therapy

Analysing the quality of Swiss national Forest inventory measurements of woody species richness

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Forest Ecosystems 2020年第3期7卷 478-488页

作者： Berthold Traub rafael O.Wüest Scientific Service nFi Swiss Federal Research Institute WSLZürcherstrasse 1118903BirmensdorfSwitzerland Spatial Evolutionary Ecology Swiss Federal Research Institute WSLZürcherstrasse 1118903BirmensdorfSwitzerland

Background: Under ongoing climate and land-use change, biodiversity is continuously decreasing and monitoring biodiversity is becoming increasingly important. national Forest inventory(nFi) programmes provide valuable timeseries data on biodiversity and thus contribute to assessments of the state and trends in biodiversity, as well as ecosystem functioning. Data quality in this context is of paramount relevance, particularly for ensuring a meaningful interpretation of changes. The Swiss nFi revisits about 8%–10% of its sample plots regularly in repeat surveys to supervise the quality of ***: We analysed the relevance of observer bias with equivalence tests, examined data quality objectives defined by the Swiss nFi instructors, and calculated the pseudo-turnover(PT) of species composition, that is, the percentage of species not observed by both teams. Three attributes of woody species richness from the latest Swiss nFi cycles(3 and 4) were analysed: occurrence of small tree and shrub species(1) on the sample plot and(2) at the forest edge, and(3) main shrub and trees species in the upper ***: We found equivalent results between regular and repeat surveys for all attributes. Data quality, however,was significantly below expectations in all cases, that is, as much as 20%–30% below the expected data quality limit of 70%–80%(proportion of observations that should not deviate from a predefined threshold). PT values were about 10%–20%, and the PT of two out of three attributes decreased significantly in nFi4. This type of uncertainty –typically caused by a mixture of overlooking and misidentifying species – should be considered carefully when interpreting change figures on species richness estimates from nFi ***: Our results provide important information on the data quality achieved in Swiss nFis in terms of the reproducibility of the collected data. The three applied approaches proved to be effective for evaluating the quality of plot

关键词： Biodiversity Data quality Equivalence test Forest inventory Monitoring Observer agreement Richness Pseudo-turnover

Clinical and demographic features of patients undergoing videocapsule endoscopy management:A descriptive study

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastrointestinal Endoscopy 2024年第7期16卷 424-431页

作者： María C Mejía Luis G Piñeros Luis M Pombo Laura A León Jenny A Velásquez Aníbal A Teherán Karen P Ayala Research Center Fundación Universitaria Juan N.CorpasBogotá111321Colombia Fundación Universitaria Juan n.Corpas Bogotá111321Colombia Department of Gastroenterology Universidad Militar Nueva GranadaBogotá111711Colombia Department of Gastroenterology Hospital Universitario Clínica San RafaelBogotá111711Colombia

BACKGROUnD Video-capsule endoscopy(VCE)is an efficient tool that has proven to be highly useful in approaching several gastrointestinal *** was implemented in Colombia in 2003,however current characterization of patients undergoing VCE in Colombia is limited,and mainly comes from two investigations conducted before the SARS-CoV-2 pandemic *** To describe the characteristics of patients undergoing VCEs and establish the main indications,findings,technical limitations,and other outstanding *** A descriptive study was carried out using data from reports of VCE(PillCam SB3 system)use in a Gastroenterology Unit in Bogotá,Colombia between September 2019 and january *** and clinical variables such as indication for the VCE,gastric and small bowel transit times(GTT,SBTT),endoscopic preparation quality,and limitations were described[n(%),median(iQR)].RESULTS A total of 133 VCE reports were *** were in men with a median age of 70 *** majority had good preparation(96.2%),and there were technical limitations in 15.8%of *** main indications were unexplained anemia(91%)or occult bleeding(23.3%).The median GTT and SBTT were 14 and 30 minutes,*** frequencies of bleeding stigma(3.79%)and active bleeding(9.09%)were low,and the most frequent abnormal findings were red spots(28.3%),erosions(17.6%),and vascular ectasias(12.5%).COnCLUSiOn VCE showed high-level *** main indication was unexplained *** bleeding was the most frequent *** with artificial intelligence,VCE can improve diagnostic precision and targeted therapeutic interventions.

关键词： Endoscopy Video-capsule endoscopy Capsule endoscopy Gastrointestinal diseases Observational study Gastrointestinal bleeding

involvement of substance P and the nK-1 receptor in pancreatic cancer

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2014年第9期20卷 2321-2334页

作者： Miguel Muoz rafael Coveas Virgen del Rocío University Hospital Research Laboratory on Neuropeptides (IBIS) 41013 Seville Spain institute of neurosciences of Castilla y León (inCYL) Laboratory of Neuroanatomy of the Peptidergic Systems (Lab 14) University of Salamanca 37007 Salamanca Spain

Pancreatic cancer is the fourth leading cause of cancer related-death for both men and women and the 1-and5-year relative survival rates are 25%and 6%,***,it is urgent to investigate new antitumor drugs to improve the survival of pancreatic cancer *** peptide substance P(SP)has a widespread distribution throughout the *** binding to the neurokinin-1(nK-1)receptor,SP regulates biological functions related to cancer,such as tumor cell proliferation,neoangiogenesis,the migration of tumor cells for invasion,infiltration and metastasis,and it exerts an antiapoptotic effects on tumor *** is known that the SP/nK-1 receptor system is involved in pancreatic cancer progression:(1)pancreatic cancer cells and samples express nK-1 receptors;(2)the nK-1 receptor is overexpressed in pancreatic cancer cells in comparison with non-tumor cells;(3)nanomolar concentrations of SP induce pancreatic cancer cell proliferation;(4)nK-1 receptor antagonists inhibit pancreatic cell proliferation in a concentration-dependent manner,at a certain concentration,these antagonists inhibit100%of tumor cells;(5)this antitumor action is medi-ated through the nK-1 receptor,and tumor cells die by apoptosis;and(6)nK-1 receptor antagonists inhibit angiogenesis in pancreatic cancer *** these data suggest that the SP/nK-1 receptor system could play an important role in the development of pancreatic cancer;that the nK-1 receptor could be a new promising therapeutic target in pancreatic cancer,and that nK-1 receptor antagonists could improve the treatment of pancreatic cancer.

关键词： Pancreas Substance P neurokinin-1 receptor antagonists Apoptosis Antitumor Angiogenesis Metastasis Pancreatic cancer

Supercritical synthesis of platinum-modified titanium dioxide for solar fuel production from carbon dioxide

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Journal of Catalysis 2017年第4期38卷 636-650页

作者： Susana Tostón rafael Camarillo Fabiola Martínez Carlos Jiménez Jesusa Rincón University of Castilla‐La Mancha Department of Chemical Engineering Faculty of Environmental Sciences and Biochemistry Avda. Carlos III s/n 45071 Toledo Spain

This paper investigates the properties of TiO2‐based photocatalysts synthesised under ***,the characteristics of Pt dispersed on TiO2catalysts obtained in supercriticalCO2are discussed and compared with those of commercial *** photocatalytic activity of thesynthesised catalysts in the CO2photoreduction reaction to produce solar fuel is *** mainconclusion of the study is that photocatalysts with better or similar features,including high surfacearea,crystallisation degree,hydroxyl surface concentration,pore volume,absorbance in the visiblerange and methane production rate,to those of commercial TiO2may be produced for the reductionof CO2to fuel by synthesis in supercritical media.

关键词： Titanium dioxide Platinum Photocatalyst Metal dispersion Carbon dioxide photoreduction

Quercetin prevents spinal motor neuron degeneration induced by chronic excitotoxic stimulus by a sirtuin 1-dependent mechanism

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Translational neurodegeneration 2017年第1期6卷 310-323页

作者： rafael Lazo-Gomez Ricardo Tapia División de neurociencias Instituto de Fisiología CelularUniversidad Nacional Autónoma de MéxicoCircuito exterior s/nCiudad UniversitariaCoyoacán04510 Ciudad de MéxicoMexico

Background:Excitotoxicity is a mechanism of foremost importance in the selective motor neuron degeneration characteristic of motor neuron *** therapeutic strategies are an unmet need for these ***,such as quercetin and resveratrol,are plant-derived compounds that activate sirtuins(SiRTs)and have shown promising results in some models of neuronal death,although their effects have been scarcely tested in models of motor neuron ***:in this work we investigated the effects of quercetin and resveratrol in an in vivo model of excitotoxic motor neuron death induced by the chronic infusion ofα-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid(AMPA)into the rat spinal cord *** and resveratrol were co-infused with AMPA and motor behavior and muscle strength were assessed daily for up to ten ***,animals were fixed and lumbar spinal cord tissue was analyzed by histological and immunocytological ***:We found that the chronic infusion of AMPA[1 mM]caused a progressive motor neuron degeneration,accompanied by astrogliosis and microgliosis,and motor deficits and paralysis of the rear *** infusion ameliorated AMPA-induced paralysis,rescued motor neurons,and prevented both astrogliosis and microgliosis,and these protective effects were prevented by EX527,a very selective SiRT1 *** contrast,neither resveratrol nor EX527 alone improved motor behavior deficits or reduced motor neuron degeneration,albeit both reduced ***:These results suggest that quercetin exerts its beneficial effects through a SiRT1-mediated mechanism,and thus SiRT1 plays an important role in excitotoxic neurodegeneration and therefore its pharmacological modulation might provide opportunities for therapy in motor neuron disorders.

关键词： Motor neuron disorder Quercetin Resveratrol Sirtuin Excitotoxicity

immersed Boundary Approach to Biofilm Spread on Surfaces

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Communications in Computational Physics 2022年第1期31卷 257-292页

作者： Ana Carpio rafael Gonzalez-Albaladejo Departamento de Matematica Aplicada Universidad Complutense28040 MadridSpain

We propose a computational model to study the growth and spread of bacterial biofilms on interfaces,as well as the action of antibiotics on *** membranes are represented by boundaries immersed in a fluid matrix and subject to interaction ***,division and death of bacterial cells follow dynamic energy budget rules,in response to variations in environmental concentrations of nutrients,toxicants and substances released by the *** this way,we create,destroy and enlarge boundaries,either spherical or *** forces represent details of the interaction between cells,and the interaction with the *** can investigate geometrical arrangements and the formation of porous *** simulations illustrate the evolution of top views and diametral slices of small biofilm seeds,as well as the action of *** show that cocktails of antibiotics targeting active and dormant cells can entirely eradicate a biofilm.

关键词： Hybrid multiscale models immersed boundary methods dynamic energy budget models bacterial biofilm antibiotic resistance