检索结果-南通市图书馆

ISCHEMIA trial:How to apply the results to clinical practice

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Cardiology 2021年第8期13卷 237-242页

作者： rafael vidal-perez Alberto Bouzas-Mosquera Jesus Peteiro Jose Manuel Vazquez-Rodriguez Servicio de Cardiologia Unidad de Imagen y Funcion CardiacaComplexo Hospitalario Universitario A Coruna(CHUAC)Centro de Investigacion Biomedica en Red(CIBERCV)-Instituto de Salud Carlos IIIA Coruna 15006Spain Servicio de Cardiología Complexo Hospitalario Universitario A CoruñaA Coruña 15006Spain

During the last years two questions have been continuously asked in chronic coronary syndromes:(1)Do revascularization procedures(coronary artery bypass grafting or percutaneous coronary intervention)really improve symptoms of angina?and(2)Do these techniques improve outcomes,*** they prevent new myocardial infarction events and cardiovascular death?Therefore,there was a need for a large definitive *** study was the ISCHEMIA trial,a large,multicentric trial sponsored by the National Heart,Lung,and Blood *** main trial compared coronary revascularization and optimal medical treatment(OMT)vs OMT alone in 5179 patients enrolled after a stress *** a median 3.2-year follow-up,318 primary outcome events occurred;the adjusted hazard ratio for the invasive strategy as compared with the conservative strategy was 0.93(95%confidence interval 0.80-1.08,P=0.34).The ISCHEMIA trial deeply disrupted many of our prior attitudes regarding management strategies for patients with stable coronary artery *** findings underscore the benefits of disease-modifying OMT for stable coronary artery disease *** main purposes of ischemia assessment before this trial were:Diagnostic purposes,assessment of outcome,and adding to decision-making ***,this changed after the trial *** results of ISCHEMIA might challenge the current diagnostic approach for stable angina patients recommended in the last European Society of Cardiology guidelines on chronic coronary disease that were based on studies published before the ISCHEMIA *** this editorial we propose our approach based on the ISCHEMIA study and the pretest probability for a positive test in patients with chronic coronary syndromes.

关键词： Stable angina Chronic coronary syndrome ISCHEMIA Stress testing Therapy Diagnosis

Current role and future perspectives of artificial intelligence in echocardiography

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Cardiology 2023年第6期15卷 284-292页

作者： rafael vidal-perez Julia Grapsa Alberto Bouzas-Mosquera Ricardo Fontes-Carvalho Jose Manuel Vazquez-Rodriguez Servicio de Cardiología Unidad de Imagen y Función CardíacaComplexo Hospitalario Universitario A Coruña Centro de Investigación Biomédica en Red-Instituto de Salud Carlos ⅢA Coruña 15006Spain Department of Cardiology Guys and St Thomas NHS TrustLondon SE17EHUnited Kingdom Cardiology Department Centro Hospitalar de Vila Nova de Gaia/EspinhoVilanova de Gaia 4434-502Portugal Cardiovascular R&D Centre-UnIC@RISE Department of Surgery and PhysiologyFaculty of Medicine of the University of PortoPorto 4200-319Portugal Servicio de Cardiología Complexo Hospitalario Universitario A CoruñaA Coruña 15006Spain

Echocardiography is an essential tool in diagnostic cardiology and is fundamental to clinical *** intelligence(AI)can help health care providers serving as a valuable diagnostic tool for physicians in the field of echocardiography specially on the automation of measurements and interpretation of *** addition,it can help expand the capabilities of research and discover alternative pathways in medical management specially on *** this review article,we describe the current role and future perspectives of AI in echocardiography.

关键词： Echocardiography Artificial intelligence Machine learning Deep learning Prognosis

Value of cardiac magnetic resonance on the risk stratification of cardiomyopathies

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Cardiology 2023年第10期15卷 487-499页

作者： rafael vidal-perez Mariana Brandao Wael Zaher Ruben Casado-Arroyo Alberto Bouzas-Mosquera Ricardo Fontes-Carvalho Jose Manuel Vazquez-Rodriguez Servicio de Cardiologia Unidad de Imagen y Funcion CardiacaComplexo Hospitalario Universitario A Coruña Centro de Investigacion Biomedica en Red de Enfermedades Cardiovasculares(CIBERCV)A Coruna 15006GaliciaSpain Department of Cardiology Centro Hospitalar de Vila Nova de Gaia/EspinhoVila Nova de Gaia 4434-502Portugal Department of Cardiology Hôpital ErasmeUniversite Libre de BruxellesBrussels 1070BrusselsBelgium Cardiovascular R&D Centre-UnIC@RISE Department of Surgery and PhysiologyFaculty of Medicine of the University of PortoPorto 4200-319Portugal Servicio de Cardiología Complexo Hospitalario Universitario A CoruñaA Coruña 15006A CoruñaSpain

Cardiomyopathies represent a diverse group of heart muscle diseases with varying etiologies,presenting a diagnostic challenge due to their heterogeneous *** evaluation using cardiac imaging techniques is impera-tive as symptoms can evolve over *** imaging approaches are pivotal for accurate diagnosis,treatment planning,and optimizing prognostic *** these,cardiovascular magnetic resonance(CMR)stands out for its ability to provide precise anatomical and functional *** manuscript ex-plores the significant contributions of CMR in the diagnosis and management of patients with cardiomyopathies,with special attention to risk ***’s high spatial resolution and tissue characterization capabilities enable early detec-tion and differentiation of various cardiomyopathy ***,it offers valuable insights into myocardial fibrosis,tissue viability,and left ven-tricular function,crucial parameters for risk stratification and predicting adverse cardiac *** integrating CMR into clinical practice,clinicians can tailor patient-specific treatment plans,implement timely interventions,and optimize long-term *** non-invasive nature of CMR reduces the need for invasive procedures,minimizing patient *** review highlights the vital role of CMR in monitoring disease progression,guiding treatment decisions,and identifying potential complications in patients with *** utilization of CMR has significantly advanced our understanding and management of these complex cardiac conditions,leading to improved patient outcomes and a more personalized approach to care.

关键词： Cardiac magnetic resonance Cardiomyopathies Prognosis Dilated cardiomyopathy Hypertrophic cardiomyopathy Restrictive cardiomyopathy

Cardiovascular disease and COVID-19,a deadly combination:A review about direct and indirect impact of a pandemic

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Clinical Cases 2022年第27期10卷 9556-9572页

作者： rafael vidal-perez Mariana Brandão Michal Pazdernik Karl-Patrik Kresoja Myriam Carpenito Shingo Maeda Rubén Casado-Arroyo Saverio Muscoli Janine Poss Ricardo Fontes-Carvalho Jose Manuel Vazquez-Rodriguez Servicio de Cardiología Unidad de Imagen y Función CardíacaComplexo Hospitalario Universitario A Coruña Centro de Investigación Biomédica en Red-Instituto de Salud Carlos ⅢA Coruña 15006Spain Department of Cardiology Centro Hospitalar de GaiaGaia 4400-020Portugal Intensive Care Unit Department of CardiologyInstitute for Clinical and Experimental Medicine PraguePrague 14021Czech Republic Heart Center Leipzig University of LeipzigLeipzig 04289Germany Unit of Cardiac Sciences Department of MedicineCampus Bio-Medico University of RomeRome 00128Italy Arrhythmia Advanced Therapy Center AOI Universal HospitalKawasaki 210-0822Japan Department of Cardiology Hôpital ErasmeUniversitéLibre de BruxellesBrussels 1070Belgium Unit of Cardiology Policlinico Tor VergataRome 00133Italy Department of Surgery and Physiology Faculty of Medicine of the University of PortoPorto 4200-319Portugal

Coronavirus disease 2019(COVID-19) is known to present with respiratory symptoms,which can lead to severe pneumonia and respiratory ***,it can have multisystem complications such as cardiovascular *** cardiovascular manifestations reported comprise myocarditis,cardiogenic shock,arrhythmias,pulmonary embolism,deep vein embolism,acute heart failure,and myocardial *** is also an indirect impact of the pandemic on the management of cardiovascular care that has been shown clearly in multiple *** this review,we summarize the deadly relation of COVID-19 with cardiovascular events and the wider impact on several cardiovascular care areas by the pandemic situation。

关键词： COVID-19 Cardiovascular diseases Pandemic Heart failure Telemedicine Prognosis

Diagnostic and prognostic value of cardiac imaging in amyloidosis

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Cardiology 2020年第12期12卷 599-614页

作者： rafael vidal-perez Raquel Vázquez-García Gonzalo Barge-Caballero Alberto Bouzas-Mosquera rafaela Soler-Fernandez Jose Maria Larrañaga-Moreira Maria Generosa Crespo-Leiro Jose Manuel Vazquez-Rodriguez Servicio de Cardiología Unidad de Imagen y Función CardíacaComplexo Hospitalario Universitario A Coruña(CHUAC)Santiago de Compostela 15706A CoruñaSpain Servicio de Cardiología Complexo Hospitalario Universitario A Coruña(CHUAC)A Coruña 15006A CoruñaSpain Servicio de Cardiología Complexo Hospitalario Universitario A CoruñaUnidad de Insuficiencia Cardiaca Avanzada y Trasplante CardiacoInstituto de Investigación Biomédica de A Coruña(INIBIC)Centro de Investigación Biomédica en Red(CIBERCV)-Instituto de Salud Carlos IIIA Coruña 15006A CoruñaSpain

Amyloidosis is an infiltrative disease caused by extracellular protein deposition that has accumulated a lot of scientific production in recent *** types of amyloidosis can affect the *** amyloidosis and light chain amyloidosis are the two most common types of cardiac *** entities have a poor prognosis,so accurate diagnostic techniques are imperative for determining an early therapeutic *** advances in cardiac imaging and diagnostic strategies show that these tools are safe and can avoid the use of invasive diagnostic techniques to histological confirmation,such as endomyocardial *** performed a review on the diagnostic and prognostic implications of different cardiac imaging techniques in cardiac *** mainly focus on reviewing echocardiography,cardiac magnetic resonance,computed tomography and nuclear imaging techniques and the different safety measurements that can be done with each of them.

关键词： Cardiac imaging techniques Transthyretin cardiac amyloidosis Immunoglobulin light-chain amyloidosis Echocardiography Magnetic resonance imaging Nuclear imaging

Social media in cardiology:Reasons to learn how to use it

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Cardiology 2019年第10期11卷 217-220页

作者： rafael vidal-perez Jose Juan Gómez de Diego Julia Grapsa Ricardo Fontes-Carvalho Jose Ramon Gonzalez-Juanatey Heart Failure Unit Cardiology DepartmentHospital Clinico Universitario de SantiagoSantiago de Compostela 15706A CorunaSpain Centro de Investigación Biomédica en Red de Enfermedades Cardiovasculares SpainSantiago de Compostela 15706A CorunaSpain Cardiovascular Institute Hospital Universitario San CarlosMadrid 28040Spain Cardiology Department St Bartholomew HospitalBarts Health TrustLondon EC1A 7BEUnited Kingdom Cardiology Department Centro Hospitalar GaiaUniversity of PortoPorto 4434-502Portugal

Social media has changed the way we learn,educate,and interact with our *** dynamic nature of social media and their immediate availability through our portable devices(smartphones,tablets,smartwatches,etc.)is quickly transforming the way we participate in *** scope of these digital tools is broad as they deal with many different aspects:Teaching and learning,case discussion,congresses coverage,peer to peer interaction,research are examples worth *** scientific societies considered more innovative,are promoting these tools between their *** new concepts need to be known by the cardiologists to stay updated,as countless information is moving rapidly through these *** summarize the main reasons why learning how to use these tools to be part of the conversation is essential for the cardiologist in training or fully stablished.

关键词： Social media Cardiology Congress Learning Teaching Interaction Cardiovascular diseases Impact Factor Portable devices Smartphone Tablet

Myocardial infarction with non-obstructive coronary arteries: A comprehensive review and future research directions

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Cardiology 2019年第12期11卷 305-315页

作者： rafael vidal-perez Charigan Abou Jokh Casas Rosa Maria Agra-Bermejo Belén Alvarez-Alvarez Julia Grapsa Ricardo Fontes-Carvalho Pedro Rigueiro Veloso Jose Maria Garcia Acuña Jose Ramon Gonzalez-Juanatey Cardiology Department Hospital Clinico Universitario de SantiagoSantiago de Compostela 15706Spain Centro de Investigación Biomédica en Red de Enfermedades Cardiovasculares(CIBERCV) Santiago de Compostela 15706Spain Cardiology Department St Bartholomew HospitalBarts Health TrustLondon EC1A 7BEUnited Kingdom Cardiology Department Centro Hospitalar GaiaVila Nova Gaia 4434-502Portugal Faculty of Medicine University of Porto Porto 4200-319Portugal

Acute coronary syndromes constitute a variety of myocardial injury presentations that include a subset of patients presenting with myocardial infarction with non-obstructive coronary arteries(MINOCA).This acute coronary syndrome differs from type 1 myocardial infarction(MI)regarding patient characteristics,presentation,physiopathology,management,treatment,and ***-thirds of MINOCA subjects present ST-segment elevation;MINOCA patients are younger,are more often female and tend to have fewer cardiovascular risk ***,MINOCA is a working diagnosis,and defining the aetiologic mechanism is relevant because it affects patient care and *** the absence of relevant coronary artery disease,myocardial ischaemia might be triggered by an acute event in epicardial coronary arteries,coronary microcirculation,or *** causes of MINOCA include coronary plaque disruption,coronary dissection,and coronary *** MINOCA mechanisms involve microvascular coronary spasm,takotsubo syndrome(TTS),myocarditis,and coronary *** angiography with non-significant coronary stenosis and left ventriculography are first-line tests in the differential study of MINOCA *** diagnostic arsenal includes invasive and non-invasive *** history and echocardiography can help indicate vasospasm or thrombosis,if one finite coronary territory is affected,or specify TTS if apical ballooning is *** ultrasound,optical coherence tomography,and provocative testing are *** magnetic resonance is a cornerstone in myocarditis *** is not a benign diagnosis,and its polymorphic forms differ in *** care varies across centres,and future multi-centre clinical trials with standardized criteria may have a positive impact on defining optimal cardiovascular care for MINOCA patients.

关键词： Myocardial infarction Non-obstructive coronary Myocardial infarction with non-obstructive coronary arteries Management Prognosis

Subclinical carotid atherosclerosis predicts all-cause mortality and cardiovascular events in obese patients with negative exercise echocardiography

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Cardiology 2019年第1期11卷 24-36页

作者： rafael vidal-perez Raúl Franco-Gutiérrez Alberto J Pérez-Pérez Virginia Franco-Gutiérrez Alberto Gascón-Vázquez Andrea López-López Ana María Testa-Fernández Carlos González-Juanatey Department of Cardiology Hospital Universitario Lucus Augusti Department of Otolaryngology Hospital Carmen y Severo Ochoa Faculty of Medicine University of Santiago de Compostela

BACKGROUND Obesity is a major health problem due to its high prevalence. The relationship between obesity and cardiovascular disease is unclear. Some studies agree that certain conditions associated with obesity, such as physical inactivity or cardiovascular risk factors, are responsible for cardiovascular risk excess among obese people. Carotid intima-media thickness and carotid plaques(CP) have been associated with cardiovascular adverse events in healthy populations, and recent data suggest a higher prevalence of subclinical carotid atherosclerosis in obese and metabolically unhealthy patients. However, there are no studies correlating subclinical atherosclerosis and adverse events(AE) in obese *** To determine the association between carotid disease and AE in obese patients with negative exercise echocardiography(EE).METHODS From January 1, 2006 to December 31, 2010, 2000 consecutive patients with a suspicion of coronary artery disease were submitted for EE and carotid ultrasonography. Exclusion criteria included previous vascular disease, left ventricular ejection fraction < 50%, positive EE, significant valvular heart disease and inferior to submaximal EE. An AE was defined as all-cause mortality,myocardial infarction and cerebrovascular accident. Subclinical atherosclerosis was defined as CP presence according to Manheim and the American Society of Echocardiography *** Of the 652 patients who fulfilled the inclusion criteria, 226(34.7%) had body mass indexes ≥ 30 kg/m2, and 76 of them(33.6%) had CP. During a mean follow-up time of 8.2(2.1) years, 27 AE were found(11.9%). Mean event-free survival at 1, 5 and 10 years was 99.1%(0.6), 95.1%(1.4) and 86.5%(2.7), respectively. In univariate analysis, CP predicted AE [hazard ratio(HR) 2.52, 95% confidence interval(CI) 1.17-5.46; P = 0.019]. In multivariable analysis, the presence of CP remained a predictor of AE(HR 2.26, 95%CI 1.04-4.95, P = 0.041). Other predictors identified were glomerular

关键词： Carotid intima media thickness Carotid plaque Carotid disease Myocardial infarction Mortality Stroke Exercise stress echocardiography

Olfactory receptors in neural regeneration in the central nervous system

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第9期20卷 2480-2494页

作者： rafael Franco Claudia Garrigós Toni Capó Joan Serrano-Marín rafael Rivas-Santisteban Jaume Lillo Molecular Neurobiology Laboratory Department of Biochemistry and Molecular BiomedicineFacultat de BiologiaUniversitat de BarcelonaBarcelonaSpain CiberNed Network Center for Biomedical Research in Neurodegenerative Diseases Spanish National Health Institute Carlos ⅢMadridSpain School of Chemistry Universitat de BarcelonaBarcelonaSpain Department of Biochemistry and Physiology School of Pharmacy and Food SciencesUniversitat de BarcelonaBarcelonaSpain Laboratory of Computational Medicine Biostatistics UnitFaculty of MedicineAutonomous University of BarcelonaCampus BellaterraBarcelonaSpain

Olfactory receptors are crucial for detecting odors and play a vital role in our sense of smell,influencing behaviors from food choices to emotional *** receptors also contribute to our perception of flavor and have potential applications in medical diagnostics and environmental *** ability of the olfactory system to regenerate its sensory neurons provides a unique model to study neural regeneration,a phenomenon largely absent in the central nervous *** gained from how olfactory neurons continuously replace themselves and reestablish functional connections can provide strategies to promote similar regenerative processes in the central nervous system,where damage often results in permanent *** the molecular and cellular mechanisms underpinning olfactory neuron regeneration could pave the way for developing therapeutic approaches to treat spinal co rd injuries and neurodegenerative diseases like Alzheimer's *** ctory receptors are found in almost any cell of eve ry orga n/tissue of the mammalian *** ectopic expression provides insights into the chemical structures that can activate olfactory *** addition to odors,olfactory receptors in ectopic expression may respond to endogenous compounds and molecules produced by mucosal colonizing *** analysis of the function of olfactory receptors in ectopic expression provides valuable information on the signaling pathway engaged upon receptor activation and the receptor's role in proliferation and cell differentiation *** review explo res the ectopic expression of olfa ctory receptors and the role they may play in neural regeneration within the central nervous system,with particular attention to compounds that can activate these receptors to initiate regenerative *** suggests that olfactory receptors could serve as potential therapeutic targets for enhancing neural repair and recovery following central nervous syste

关键词： adenosine receptors adrenergic receptors ectopic expression G proteincoupled receptors glia neurons