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Effect of microencapsulated watermelon(Citrullus lanatus)intake on plasma amino acids and glycemic response in healthy adults

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Food Bioscience 2022年第2期46卷 450-455页

作者： Mˆonica Volino-Souza Gustavo Vieira Oliveira rafael vargas Anna Carolina Tavares Carlos Adam Conte-Junior Thiago da Silveira Alvares Nutrition and Exercise Metabolism Research Group Multidisciplinary Center UFRJ-Maca´eFederal University of Rio de JaneiroMaca´eRio de JaneiroBrazil Postgraduate Program in Food Science Chemistry InstituteFederal University of Rio de JaneiroRJBrazil Nanotechnology Network Carlos Chagas Filho Research Support Foundation of the State of Rio de Janeiro(FAPERJ)Rio de JaneiroRJ20.020-000Brazil Food and Nutrition Institute Multidisciplinary Center UFRJ-Maca´eFederal University of Rio de JaneiroMaca´eBrazil

Watermelon is an L-citrulline-rich fruit that has been used as a supplement to increase L-arginine in plasma,which in turn plays a critical role in the synthesis of nitric oxide,a molecule that regulates vascular *** rind,similar to its pulp,presents a high L-citrulline content,yet a lower concentration of sugar,which would be more convenient for individuals who need to refrain from excessive sugar ingestion(i.e.,diabetics and obese individuals).Further,ingestion of watermelon rind can be a sustainable alternative to increase plasma L-arginine,given that rind of fruits is commonly ***,we evaluated the effect of ingestion of a product derived from watermelon rind and pulp(microencapsulation in spray drier)on plasma amino acids(L-citrulline,L-arginine and L-ornithine),glucose,and *** participants(28.36±5.70 years)were enrolled in a single blind,cross-over and randomized *** ingested microencapsulated watermelon rind and pulp(containing 4 g of L-citrulline)plasma amino acids,glucose,and insulin were evaluated before and 30,60,90 and 120 min after *** was observed that both microencapsulated watermelon rind and pulp increased L-citrulline through 120 min and microencapsulated watermelon rind significantly increased L-arginine at 30 *** addition,microencapsulated watermelon rind and pulp similarly increased plasma glucose and insulin *** conclusion,these findings suggest that both microencapsulated watermelon rind and pulp are effective to increase plasma L-citrulline and microencapsulated watermelon rind effectively increases plasma *** addition,rind and pulp promote similar changes on plasma glucose and insulin.

关键词： L-citrulline Watermelon rind Microencapsulation Glucose Plasma amino acids

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Safety and visual outcomes following posterior chamber phakic intraocular lens bilensectomy

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Eye and Vision 2020年第1期7卷 328-335页

作者： Veronica vargas Jorge L.Alió rafael I.Barraquer Justin Christopher D’Antin Cristina García Francisco Duch Joan Balgos Jorge LAliódel Barrio Vissum Instituto Oftalmológico de Alicante AlicanteSpain Division of Ophthalmology Universidad Miguel HernándezAlicanteSpain Institut Universitari Barraquer Universitat Autònoma de BarcelonaBarcelonaSpain Centro de Oftalmología Barraquer BarcelonaSpain Universitat Internacional de Catalunya BarcelonaSpain Clínica Real Vision MadridSpain Instituto Catalán de Retina(ICR)unidad de Cirugía Refractiva BarcelonaSpain

Background:To evaluate the safety,efficacy,refractive outcomes and causes for bilensectomy(phakic intraocular lens–pIOL–explantation with cataract surgery and pseudophakic intraocular lens implantation)in patients previously implanted with posterior chamber ***:This multi-center retrospective study included 87 eyes of 55 patients who underwent bilensectomy for posterior chamber pIOL with a follow up time of 12 *** uncorrected and best corrected distance visual acuities(UDVA,CDVA),endothelial cell density before and after bilensectomy were assessed,as well as the cause of bilensectomy and intra or postoperative ***:There was a statistically significant improvement in uncorrected and best corrected visual acuities after bilensectomy(p=0.00).The main reason for bilensectomy was cataract development(93.1%of the cases),followed by miscalculation of lens size,and corneal *** endothelial cell count remained stable without a statistically significant change after surgery(p=0.67).The refractive efficacy index was 0.8,none of the patients lost lines of CDVA after surgery,73%of the patients were within±1 D(spherical equivalent)of the target *** complications were one posterior capsule rupture with the intraocular lens(IOL)implanted in the sulcus,and 3 eyes required the use of pupil expanders for adequate pupil ***,one eye developed retinal *** three pIOLs models explanted were the Implantable Collamer Lens(ICL),Implantable Phakic Contact Lens(IPCL)and the Phakic Refractive Lens(PRL).Conclusions:Good safety and visual outcomes were observed 1 year after bilensectomy for posterior chamber phakic intraocular lenses(PC pIOLs).There were few intra and postoperative complications and there was no significant endothelial cell loss after the bilensectomy procedure.

关键词： Bilensectomy Posterior chamber phakic intraocular lenses Cataract Endothelial cell count Visual outcomes Postoperative complications Intraoperative complications

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ACE Score Identifies HBeAg-negative Inactive Carriers at a Single-point Evaluation,Regardless of HBV Genotype

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Journal of Clinical and Translational Hepatology 2022年第6期10卷 1068-1076页

作者： Luisa Roade Mar Riveiro-Barciela Adriana Palom Francisco Rodríguez-Frías Marta Bes Ariadna Rando María Teresa Salcedo Rosario Casillas Elena vargas-Accarino David Tabernero Silvia Sauleda rafael Esteban María Buti Liver Unit Internal Medicine DepartmentHospital Universitari Vall d’HebronVall d’Hebron Barcelona Hospital CampusBarcelonaSpain Universitat Autònoma de Barcelona(UAB) Department of MedicineBarcelonaSpain Universitat Au-tònoma de Barcelona(UAB) Department of Biochemistry and Molecular BiologyBarcelonaSpain Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas(CIBERehd) Instituto de Salud Carlos IIIMadridSpain Liver Pathology Lab Biochemistry and Microbiology Departments(Clinical Laboratories)Hospital Universitari Vall d’HebronVall d’Hebron Barcelona Hospital CampusBarcelonaSpain Vall d’Hebron Institut de Recerca(VHIR) Liver Diseases GroupBarcelonaSpain Transfusion Safety Laboratory Banc de Sang i TeixitsServei Catalàde la SalutBarcelonaSpain De-partment of Pathology Hospital Universitari Vall d’HebronUniversitat Autònoma de BarcelonaBarcelonaSpain

Background and Aims:Hepatitis B virus(HBV)biomark-ers have been used for a better categorization of patients,even though the lack of simple algorithms and the impact of genotypes limit their *** aim was to assess the usefulness of noninvasive markers for the identification of HBV inactive carriers(ICs)in a single-point evaluation and to design a predictive model for their ***-ods:This retrospective-prospective study included 343 consecutive HBeAg-negative ***,analytical,and virological data were collected,and a liver biopsy was performed if *** were classified at the end of follow-up as ICs,chronic hepatitis B and gray zone.A pre-dictive model was constructed,and validated by 1000-boot-strap ***:After 39 months of follow-up,298 subjects were ICs,36 were chronic hepatitis B CHB,and nine were gray ***-nine(25.9%)individuals re-quired a liver *** HBV DNA hazard ratio(HR)6.0,p<0.001),HBV core-related antigen(HBcrAg)(HR 6.5,p<0.001),and elastography(HR 4.6,p<0.001)were inde-pendently associated with the IC *** ACE score(HBV DNA,HBcrAg,elastography),obtained by bootstrapping,yielded an area under the receiver operating characteris-tics(AUROC)of 0.925(95%CI:0.880-0.970,p<0.001)for identification of *** AUROC for genotype D was 0.95,0.96 for A,0.90 for E,and 0.88 for H/*** ACE score of<1 had a positive predictive value of 99.5%,and a score≤12 points had a diagnostic accuracy of 93.8%.Conclusions:Low baseline HBV DNA,HBcrAg,and liver stiffness were in-dependently associated with the IC phase.A score including those variables identified ICs at a single-point evaluation,and might be applied to implement less intensive follow-up strategies.

关键词： Hepatitis B virus Inactive carrier Liver stiffness HBV DNA Quan-titative HBsAg Core-related antigen.

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Environmental and Economic Impact of Forest Fires in Puerto Rico 2013-2014

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Open Journal of Forestry 2015年第4期5卷 353-363页

作者： Méndez-Tejeda rafael Santos-Corrada María Ortiz-Morales Sergio Claudio-vargas Oscar Natural Science Department Atmospherical Science Laboratory University of Puerto Rico—Carolina Campus Carolina Puerto Rico School of Business and Entrepreneurship University of Turabo Gurabo Puerto Rico

This study presents an analysis of the impact of forest fires in Puerto Rico for the period from 2013-2014. The climatological factors analyzed included precipitation, temperature, relative humidity, and wind. Several factors have combined to the increase of these forest fires, among others, a decrease in precipitation during this period, as well as an increase in the human involvement in these fires from approximately 40% occurs in the night period (5:00 pm to 8:00 am), where the weather conditions do not favor the appearance of these phenomena. An increase in fires of 44% occurred in 2013 compared to 2014, causing an economic loss of $13.8 million. Fire also adversely affected the flora and fauna of the island, but this was not evaluated in this paper.

关键词： Fires Forest Wildfire Economic Impact of Forest fires Precipitation and Weather Conditions

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Influence of Vernalization and Photoperiod on the Duration of Stem Elongation and Spikelet Fertility in Wheat

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Agricultural Sciences 2014年第14期5卷 1547-1557页

作者： Osmar Rodrigues Mauro César Celaro Teixeira Edson Roberto Costenaro Leandro vargas rafael Damo Embrapa Wheat Passo Fundo Brazil University of Passo Fundo Passo Fundo Brazil

A longer stem elongation phase (from the terminal spikelet-TS to the anthesis-ANT phases) increases grain production due to an increase in spikelet fertility. However, the mechanism behind the greater number of fertile flowers that occur when the duration of stem elongation is modified by photoperiod and vernalization is not fully understood. The goal of this study was to investigate the effect of combinations of photoperiod and vernalization on the duration of stem elongation and spikelet fertility in wheat. Thus, a greenhouse experiment was performed by subjecting 13 wheat genotypes to two vernalization regimes (V0—non-vernalized plants and V40—plants with 40 vernalization days) and to two photoperiod regimes (NP—natural and NP + 6—photoperiod extended by six hours), during the stem elongation phase. The natural photoperiod increased the spikelet fertility of eight cultivars without a corresponding increased duration of the TS-ANT phase, suggesting the existence of a direct effect of photoperiod on increased spikelet fertility. Vernalization increased the duration of the TS-ANT phase, without influencing spikelet fertility. There was genetic variability in the responses to photoperiod and vernalization.

关键词： Double Ridge Terminal Spikelet Elongation

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Optimum Power in a Multi-Span DWDM System Limited by Non-Linear Effects

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Optics and Photonics Journal 2018年第12期8卷 337-347页

作者： Jose Alfredo Alvarez-Chavez rafael Sanchez-Lara Jaime rafael Ek-Ek Herman leonard.Offerhaus Manuel May-Alarcon Victor Golikov Optical Sciences Group University of Twente Enschede The Netherlands Instituto Politecnico Nacional-Centro de Investigacion e Innovacion Tecnologica Catarina Mexico Facultad de Ingenieria Universidad Autonoma del Carmen Campeche Mexico

Limitations imposed by Four-Wave Mixing (FWM), Amplified Spontaneous Emission (ASE), dispersion and Stimulated Raman Scattering (SRS) on a multi-spam DWDM system are theoretically studied. In this work, expression for the linear dispersion parameter D has been defined as a function of number of channels in order to separate FWM and SRS effects and calculates both maximum fibre length and optimum power. Additionally, our simulation results consider the effect of ASE noise from Erbium Doped Fibre Amplifiers (EDFAs). This theoretical analysis yields a set of design criteria from optimized multi-span DWDM systems.

关键词： DWDM FWM ASE SRS Dispersion EDFA

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梦想的盛典

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缤纷 2005年第9期 49-53页

作者：姚京 rafael vargas

由19个世界顶级建筑师和建筑设计小组共同设计的 Puerta America 设计酒店,于2005年7月14日在西班牙首都马德里盛大落成。

关键词：酒店皮革共同设计建筑师设计小组淹没西班牙马德里空间结构客房

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巴塞罗那Spa空间的写意之情

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城市建筑空间 2006年第10期 99-105页

作者： Tarruella LopezInterioristas rafael vargas

SPACIOMMM水疗中心是Hotel OMM增建部分的一个独立区域,整洁的空间分布,洗练的设计手法,将干净、利落、舒适的气息凝聚在这个空间里,使客人真切地感受到巴塞罗那的体贴与写意。

关键词：巴塞罗那水疗西班牙 Spa

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Artificial intelligence meets body sense: task-driven neural networks reveal computational principles of the proprioceptive pathway

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Signal Transduction and Targeted Therapy 2024年第8期9卷 3147-3149页

作者： leonard.E.van Dyck Frank Bremmer Katharina Dobs Department of Psychology Justus Liebig University GiessenGiessenGermany Max Planck Institute for Human Cognitive and Brain Sciences LeipzigGermany Center for Mind Brain and BehaviorUniversities of MarburgGiessenand DarmstadtMarburgGermany Department of Neurophysics Philipps-Universitat MarburgMarburgGermany

In a recent study published in Cell,Marin vargas and Bisi et al.1 present an innovative approach to unravel the computational principles underlying proprioceptive processing in non-human *** findings showcase the utility of task-driven modeling in advancing neuroscience and offer translational potential by providing seminal insights into the goals and mechanisms by which the brain encodes body position and movements.

关键词： networks neural principles

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建筑集市：西班牙马德里Puerta美洲酒店汇集了18位明星级建筑师风格迥异的设计——成为当代建筑风格的集合体

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照明设计 2006年第3期 50-59页

作者： Petra Steiner rafael vargas（摄影）马艳（译）

Puerta美洲酒店的外表丝毫没有泄露它里面的别有洞天。对于没有被吉恩·努维尔（Jean Nouvel）的外立面震住的参观者来说，当他们进入酒店之后．最好的东西才扑面而来。12层楼的每一层都是不同的设计师的心力结晶。出人意料的是．这些... 详细信息

Puerta美洲酒店的外表丝毫没有泄露它里面的别有洞天。对于没有被吉恩·努维尔（Jean Nouvel）的外立面震住的参观者来说，当他们进入酒店之后．最好的东西才扑面而来。12层楼的每一层都是不同的设计师的心力结晶。出人意料的是．这些材质与风格大相径庭的设计的照明设计任务落在了一家设计团队身上，总部在伦敦的ILD（Isometrix Lighting＋Design）公司被委以重任。ILD普经同参与项目的绝大多数设计师合作过，因此那些建筑大师们都同意与这家伦敦的工作室再度联手。照明设计师面对的挑战是为不同的的设计量体裁衣，除了要表达特色鲜明的建筑场景之外，还要确保五星级酒店的格调。

关键词：照明设计师五星级酒店建筑风格美洲集合体建筑师马德里西班牙

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