检索结果-南通市图书馆

Comparative analysis of microstructure,mechanical,and corrosion properties of biodegradable Mg-3y alloy prepared by selective laser melting and spark plasma sintering

引用

journal of Magnesium and Alloys 2024年第4期12卷 1496-1510页

作者： P.Minárik M.Zemková S.Šašek j.Dittrich M.Knapek F.Lukáˇc D.Koutný j.jaroš R.Král Faculty of Mathematics and Physics Charles UniversityKe Karlovu 5Praha 12116Czech Republic Research Centre University ofŽilinaUniverzitná8215/1Žilina 01026Slovakia Institute of Plasma Physics of the Czech Academy of Sciences Za Slovankou 1782/318200 Praha 8Czech Republic Institute of Machine and Industrial Design Brno University of TechnologyTechnická2896/2Brno 61669Czech Republic

This work explored possibilities of biodegradable magnesium alloy Mg-3y preparation by two modern powder metallurgy techniques–spark plasma sintering(SPS)and selective laser melting(SLM).The powder material was consolidated by both methods utilising optimised parameters,which led to very low porosity(∼0.3%)in the SLM material and unmeasurably low porosity in the SPS *** main aim of the study was the thorough microstructure characterisation and interrelation between the microstructure and the functional properties,such as mechanical strength,deformability,and corrosion *** materials showed comparable strength of∼110 MPa in tension and compression and relatively good deformability of∼9%and∼21%for the SLM and SPS materials,*** corrosion resistance of the SPS material in 0.1 M NaCl solution was superior to the SLM one and comparable to the conventional extruded *** digital image correlation during loading and the cross-section analysis of the corrosion layers revealed that the residual porosity and large strained grains have the dominant negative effect on the functional properties of the SLM *** the other hand,one of the primary outcomes of this study is that the SPS consolidation method is very effective in the preparation of the W3 biodegradable alloy,resulting in material with convenient mechanical and degradation properties that might find practical applications.

关键词： Magnesium yttrium Powder metallurgy Microstructure Mechanical strength Corrosion resistance

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

通过深度学习预测脑膜瘤的等级和病理标志物表达

引用

国际医学放射学杂志 2024年第4期 496-497页

作者： j.W.Chen y.P.Xue L.H.Ren K.Lv P.Du H.X.Cheng 胡佳圆

摘要目的建立一个深度学习（DL）模型用于预测脑膜瘤的肿瘤等级和病理标志物的表达。方法回顾性纳入2018年9月—2021年12月在2家医院接受手术切除的1 192例

关键词：

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Exploring the Prevalence and Contributing Factors of Depression among Sickle Cell Anemia Patients in Saudi Arabia’s jazan Region

引用

International journal of Mental Health Promotion 2024年第5期26卷 351-359页

作者： Abdullah A.Alharbi Ahmad y.Alqassim Mohammed A.muaddi Najat H.Aldubayyan Rana I.Abuhadi Futon A.Akoor Sarah j.Mobarki Imtenan A.Oberi Ghaidaa H.Alharbi yara Ajeebi Adnan M.Alkhayat Hafiz Malhan Mohammed Bakkar Anwar M.Makeen Family and Community Medicine Department Faculty of MedicineJazan UniversityJazan45142Saudi Arabia Laboratory Department King Fahd Central HospitalMinistry of HealthJazan45142Saudi Arabia Internal Medicine Department Prince Mohammad bin Nasser HospitalMinistry of HealthJazan45142Saudi Arabia Hematology Department King AbdulAziz Medical City for National GuardRiyadh11426Saudi Arabia

Sickle Cell Anemia(SCA)is a prevalent genetic condition in Saudi Arabia,particularly in the jazan *** study’s purpose was to assess the prevalence of de-pression among individuals with SCA in this area and to identify the factors associated with this *** study involved 391 adult participants,all patients in the hematology center of Prince Mohammed bin Nasser Hospital(PMNH).Data was collected through an anonymous interview questionnaire–the Arabic version of the Patient Health Questionnaire-9(PHQ-9)–between March–May *** questionnaire covered socio-demographic information and variables related to the participant’s SCA history,such as pain levels,frequency of pain,hospitalization duration,and frequency of blood *** variables underwent Chi-square and One-way ANOVA testing,followed by multivariate *** study found a 42%prevalence of depression among the SCA *** significantly linked with heightened depression levels included being widowed or divorced,experiencing frequent and severe pain,and longer duration of hospital *** educational level of at least a bachelor’s degree was also a significant *** study reveals a high prevalence of depression among SCA patients in the jazan *** underscores the need for policymakers to educate both physicians and patients about the importance of mental health in SCA *** study also highlights the need for more research into the specific causes and effects of depressive symptoms in SCA patients to inform the creation of effective management plans.

关键词： Sickle cell anemia prevalence depression public health policy jazan region Saudi Arabia

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Improving colorectal cancer screening programs

引用

World journal of Gastroenterology 2024年第22期30卷 2849-2851页

作者： Oscar j Cordero Lucia Mosquera-Ferreiro Iria Gomez-Tourino Department of Biochemistry and Molecular Biology University of Santiago de CompostelaSantiago de Compostela 15782Spain Centre for Research in Molecular Medicine and Chronic Diseases(CimuS) University of Santiago de CompostelaSantiago de Compostela 15782GaliciaSpain

In this editorial we comment on the article by Agatsuma et al published in the World journal of *** suggest policies for more effective colorectal *** is the main policy that has led to lower mortality rates in later years among the population that was eligible for *** is the gold standard tool for screening and has preventive effects by removing precancerous or early malignant ***,colonoscopy is an invasive process,and fecal tests such as the current hemoglobin immunodetection were developed,followed by endoscopy,as the general tool for population screening,avoiding logistical and economic *** so,participation and adherence rates are *** screening options are being developed with the idea that if people could choose between the ones that best suit them,participation in population-based screening programs would *** tests,such as a recent one that detects cell-free DNA shed by tumors called circulating tumor DNA,showed a similar accuracy rate to stool tests for cancer,but were less sensitive for advanced precancerous *** the time when the crosstalk between the immune system and cancer was being established as a new hallmark of cancer,novel immune system-related biomarkers and information on patients’immune parameters,such as cell counts of different immune populations,were studied for the early detection of colorectal cancer,since they could be effective in asymptomatic people,appearing earlier in the adenoma-carcinoma development compared to the presence of fecal ***26,for example,detected 80.37%of advanced *** reach as many eligible people as possible,starting at an earlier age than current programs,the direction could be to apply tests based on blood,urine or salivary fluid to samples taken during routine visits to the primary health system.

关键词： Mortality rates Colorectal cancer Screening Biomarker Fecal hemoglobin immunodetection Soluble sCD26 Colonoscopy Immunoscores

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

新辅助化疗加卡瑞利珠单抗治疗局部晚期宫颈癌(NACI研究):一项多中心、单臂、2期试验

引用

中国临床药理学杂志 2024年第1期40卷 149-149页

作者： LI K Z CHEN j HU y j 王超群

引自:LI K Z,CHEN j,HU y j,et *** chemotherapy plus camrelizumab for locally advanced cervical cancer(NACI study):a multicentre,single-arm,phase 2 trial[j/OL].Lancet Oncol,2023.2023-12-01[2023-12-05].https://***/38048802/.局部晚期宫颈癌约占全球宫颈癌病例的37%,由于治疗选择有限,预后较差。免疫检查点抑制剂在新辅助治疗中可以解决这些挑战。本研究的目的是探讨新辅助化疗-免疫治疗局部晚期宫颈癌的有效性和安全性。在这项在中国8家三级医院进行的单臂2期试验中,招募了年龄在18~70岁的未经治疗的宫颈癌患者(ⅠB3、ⅡA2或ⅡB/ⅢC1r,肿瘤直径≥4 cm(国际妇产科学联合会,2018),东方肿瘤合作组织(Eastern Cooperative Oncology Group,ECOG)状态为0或1。符合条件的患者接受了一个周期的启动双重化疗(75~80 mg·m^(-2)顺铂,静脉注射,加上260 mg·m^(-2)白蛋白结合型紫杉醇,静脉注射),随后在第1天进行了两个周期的联合化疗(顺铂加白蛋白结合型紫杉醇),在第2天给予卡瑞利珠单抗(200 mg,静脉注射),治疗周期间隔为3周。

关键词：局部晚期宫颈癌白蛋白结合型紫杉醇新辅助化疗新辅助治疗联合化疗妇产科学 chemotherapy 免疫治疗

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Diterpenoid Alkaloids from Aconitum Nagarum var. Lasiandrum

引用

Chinese Chemical Letters 2000年第11期11卷 1005-1006页

作者： Dong j.y. Li Z.y. Li L. Key Lab. Fermentative Eng. I. Yunnan University Kunming 650091 China Dept. of Environmental Engineering Kunming Inst. of Sci. and Technology Kunming 650093 China Department of Chemistry Yunnan University Kunming 65009 China

Two new diterpenoids, nagadine 1 and 14-benzoylsachaconitine 2 were isolated from the roots of Aconitum nagarum. Their structures were elucidated as 1 and 2 on the basis of spectral analysis.

关键词： Diterpenoid Alkaloids from Aconitum Nagarum var Lasiandrum EIMS Wang

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

AN OPTIMAL CONTROL PROBLEM FOR A LOTKA-VOLTERRA COMPETITION MODEL WITH CHEMO-REPULSION

引用

Acta Mathematica Scientia 2024年第2期44卷 721-751页

作者： Diana I.HERNÁNDez Diego A.RUEDA-GOMez Élder j.VILLAMIZAR-ROA Universidad Industrial de Santander Escuela de MatemáticasA.A.678BucaramangaColombia

In this paper we study a bilinear optimal control problem for a diffusive Lotka-Volterra competition model with chemo-repulsion in a bounded domain of ℝ^(ℕ),N=2,*** model describes the competition of two species in which one of them avoid encounters with rivals through a chemo-repulsion *** prove the existence and uniqueness of weak-strong solutions,and then we analyze the existence of a global optimal solution for a related bilinear optimal control problem,where the control is acting on the chemical ***,we derive first-order optimality conditions for local optimal solutions using the Lagrange multipliers ***,we propose a discrete approximation scheme of the optimality system based on the gradient method,which is validated with some computational experiments.

关键词： Lotka-Volterra chemo-repulsion optimal control optimality conditions

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

信迪利单抗联合化疗治疗不可切除的胃或胃食管结合部癌

引用

中国临床药理学杂志 2024年第9期40卷 1271-1271页

作者： XU j jIANG H PAN y 吴焕贤

每年全球有超过100万人被诊断患有胃和食管胃交界处癌症,目前有效的治疗方法很少。信迪利单抗是一种与程序性细胞死亡蛋白1(programmed cell death1,PD-1)结合的重组人IgG4单克隆抗体,与化疗联合应用已显示出良好的疗效。本研究是在中... 详细信息

每年全球有超过100万人被诊断患有胃和食管胃交界处癌症,目前有效的治疗方法很少。信迪利单抗是一种与程序性细胞死亡蛋白1(programmed cell death1,PD-1)结合的重组人IgG4单克隆抗体,与化疗联合应用已显示出良好的疗效。本研究是在中国62家医院进行的一项随机、双盲、安慰剂对照的第Ⅲ期临床试验,旨在比较接受信迪利单抗联合化疗与接受安慰剂联合化疗治疗的不可切除的局部晚期或转移性胃或食管胃交界处癌症患者的总生存期。

关键词：安慰剂对照 Ⅲ期临床试验联合化疗不可切除化疗联合应用 IgG4 death 单克隆抗体

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

3D printing of patient-specific 316L–stainless–steel medical implants using fused filament fabrication technology: two veterinary case studies

引用

Bio-Design and Manufacturing 2022年第4期5卷 808-815页

作者： j.M.Chacón P.j.Núñez M.A.Caminero E.García-Plaza j.Vallejo M.Blanco Escuela Técnica Superior de Ingeniería Industrial Universidad de Castilla-La ManchaAvdaCamilo JoséCela213071 Ciudad RealSpain Protresde Ingeniería y Soluciones C/Solana 60nave 313005 Ciudad RealSpain

Biomedical fracture fixation implants have complex sculptured geometries to adapt perfectly to fractured bones,making them difficult and expensive to manufacture with conventional machining methods. Fused filament fabrication(FFF) is a very popular Additive Manufacturing technology that simplifies the manufacture of parts with complex geometries, making it ideal for the manufacture of customized medical implants.

关键词： steel fracture fused

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Blood Pressure Profile and Glycemic Control of Type 2 Diabetics and Hypertensives at the yalgado Ouedraogo University Hospital: A Review of 116 Cases

引用

World journal of Cardiovascular Diseases 2024年第1期14卷 61-76页

作者： G. R. C. Millogo A. Thiam y. Kambiré E. Nongkouni S. E. Dabiré L. j. Kagambéga j. K. Kologo V. N. yaméogo P. Zabsonré Department of Cardiology Yalgado Ouédraogo University Hospital Ouagadougou Burkina Faso Department of Cardiology Tengandogo University Hospital Ouagadougou Burkina Faso

Objective: The association hypertension and diabetes is important. The two pathologies may influence each other. The aim was to study the correlation between glycemic control and blood pressure control and to determine the factors associated with blood pressure control. Methodology: This was a descriptive cross-sectional study with an analytical focus over 7 months. Patients were recruited as outpatients and all underwent ambulatory blood pressure measure, glycated hemoglobin and creatinine measurements, and assessment of compliance with treatment. Results: During this period 116 patients were collected. The predominance was female 69%. The mean age of the patients was 62 ± 7 years with a peak between 60 and 70 years. The average age of hypertension was 12 years and that of diabetes 6 1/2 years. The most frequently associated cardiovascular risk factor was a sedentary lifestyle (71.5%) after age. 57.8% of patients were not controlled at the office, with a predominance of systolic hypertension (58.2%). 61.6% of patients were controlled by ambulatory blood pressure measure, a rate of 47.8% of white coat hypertension. Glycemic control was observed in 42.2% of cases and 87% of patients had good renal function (glomerular filter rate ≥ 60 ml/mn). Therapeutic compliance was good in 53.4% of cases and dual therapy was the most used therapeutic modality 44.8% (52 patients) followed by triple therapy. The factors associated with poor blood pressure control were glycemic imbalance, non-compliance and monotherapy. Dual therapy had a protective effect. Conclusion: The association of hypertension and type 2 diabetes is frequent. The risk of occurrence increases with age. Ambulatory blood pressure measure is the best method to assess blood pressure control. Optimization of blood pressure control should also include optimization of glycemic control.

关键词： Blood Pressure Control Glycemic Control Hypertensive and Diabetic Patients

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：