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Ce.lular & Mole.ular Immunology 2021年第4期18卷 919-935页

作者： Pilar Martin rafael Blanco-Dom fngue. Raque. Sanche.-Diaz Vascular Pathophysiology Are. Centro Nacional de Investigaciones Cardiovasculares(CNIC)MadridSpain CIBe.CV MadridSpain

In the.last de.ade.approache. base. on T ce.ls and the.r immunomodulatory re.e.tors have.e.e.ge. as a solid improve.e.t in tre.tme.ts for various type. of ***,the.role. of the.e.mole.ule. in the.the.ape.tic conte.t of autoimmune.and cardiovascular dise.se. are.still re.ative.y ***,we.re.ie. the.be.t known and most com m only use. immunomodulatory T ce.l re.e.tors in clinical practice.PD-1 and CTLA-4),along with the.re.t of the.re.e.tors with known functions in animal mode.s,which have.gre.t pote.tial as modulators in human pathologie. in the.me.ium *** ong the.e.othe. re.e.tors is the.re.e.tor CD69,which has re.e.tly be.n de.cribe. to be.e.pre.se. in mouse.and human T ce.ls in autoimmune.and cardiovascular dise.se. and ***,inhibition of the.e.re.e.tors individually or in combination by drugs or monoclonal antibodie. ge.e.ate. a loss of immunological tole.ance.and can trigge. multiple.autoimmune.disorde.s in diffe.e.t organs and immune.re.ate. adve.se.*** the.coming de.ade.,knowle.ge.on the.functions of diffe.e.t immunomodulatory re.e.tors will be.pivotal for the.de.e.opme.t of ne. and be.te. the.apie. with le.s harmful side.*** this re.ie.,we.discuss the.role. of the.e.re.e.tors in the.control of immunity from a pe.spe.tive.focuse. on the.ape.tic pote.tial in not only cance. but also autoimmune.dise.se.,such as syste.ic lupus e.ythe.atosus,autoimmune.diabe.e. and rhe.matoid arthritis,and cardiovascular dise.se.,such as athe.oscle.osis,acute.myocardial infarction,and myocarditis.

关键词： Immunomodulatory re.e.tors Autoimmune.dise.se. T ce.ls Immunothe.apy

e.vironme.tal Approach for e.e.gy Audits on Gove.nme.t Buildings: A Me.ican Case.for the.Air Conditioning Syste.

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Journal of e.vironme.tal Prote.tion 2018年第3期9卷 278-293页

作者： Luis e. Ve.azque. rafael Pe.e.-Rios Nora e. Munguia David S. Ze.e.a Carla Ne.de.t Javie. e.que. Sustainability Graduate.Program Industrial Engineering Department University of Sonora Hermosillo Mexico Fre.lance.Sustainability Consultant Hermosillo Mexico

In the.face.of the.climate.change. e.e.gy consumption is one.of the.main issue. to be.solve.. e.e.gy audits are.use.ul tools that may contribute.to de.e.op e.e.gy e.ficie.cy initiative.. The.purpose.of this pape. is to provide.insights into how e.e.gy audits, with a scope.on air conditioning (AC) syste.s, contribute.to de.e.op e.e.gy e.ficie.cy options for a gove.nme.t building in the.city of He.mosillo, Me.ico. The.me.hodology is base. in the.e.e.gy audit frame.ork propose. by the.Ame.ican Socie.y of He.ting, Re.rige.ating and Air-Conditioning e.gine.rs (ASHRAe.. Re.ults show that, in a typical day of maximum consumption, AC re.re.e.ts 64% of the.total e.e.trical consumption, while.office.e.uipme.t accounte. for 22%, and lighting 14%. Additionally, AC syste. has a ye.rly consumption of 54,419.40 kWh with an e.ission e.timate.of 24.92 tons of CO2-e./ye.r. Thre. approache. for e.e.gy e.ficie.cy proposals we.e.addre.se. through AC syste.s: Improve.e.t of the.ope.ation and consumption habits, mainte.ance.and re.onditioning of facilitie., and re.lace.e.t of AC units. While.Me.ico has inte.national commitme.ts through e.vironme.tal tre.tie. re.ate. to contribute.to climate.change.mitigation, this study shows that, at le.st one.gove.nme.t building still produce. pote.tial impacts that can be.de.e.re. by addre.sing structural and be.avioral change. re.ate. to AC ope.ation. Finally, this study may be.use. as re.e.e.ce.for e.e.gy e.ficie.cy practitione.s or de.ision-making authoritie. in the.public administration fie.d for de.e.oping be.te. e.e.gy policie. for gove.nme.t buildings.

关键词： e.e.tricity Consumption e.e.gy Audits e.e.gy e.ficie.cy e.vironme.tal Impact

Sport participation and vigilance.in childre.:Influe.ce.of diffe.e.t sport e.pe.tise

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Journal of Sport and He.lth Scie.ce 2018年第4期7卷 497-504页

作者： rafael Balle.te. Flore.tino Hue.tas e.rique.Molina Danie. Sanabria Faculty of Physical e.ucation ＆ Sport Scie.ce. Catholic University of ValenciaValeneia 46900Spain Mind Brain and Be.avior Re.e.rch Ce.te. University of GranadaGranada 18071Spain ）Corre.ponding author.e.mail addre.s：danie.@ugr.e.

Purpose. The.pre.e.t study aime. to inve.tigate.the.re.ationship be.we.n diffe.e.t type. of sport e.pe.tise.（e.te.nally-pace. vs. se.f-pace. sports） and vigilance.pe.formance.in childre. by e.aluating the.cardiovascular fitne.s le.e. of the.participants. Me.hods： Thre. groups of childre. （11.0 ± 0.2 ye.rs） diffe.e.tiate. in te.ms of the.r re.ular sport participation （football playe.s, n = 20; track and fie.d athle.e., n = 20; non-athle.ic controls, n = 20） took part in the.study. In one.se.sion, participants pe.forme. the.Le.e. Multi-stage.fitne.s te.t to e.timate.the.r ae.obic fitne.s le.e.. In anothe. se.sion, participants comple.e. the.Psychomotor Vigilance.Task （PVT） to e.aluate.the.r vigilance.pe.formance.unde. 2 conditions of ve.ocity de.ands （normal vs. spe.d）. Re.ults： The.re.ults re.e.le. that both groups of sport practitione.s had highe. cardiovascular fitne.s than non-athle.e.controls. In contrast, no significant diffe.e.ce. in the.pe.formance.PVT we.e.found be.we.n track and fie.d athle.e. and controls. Crucially, football playe.s showe. be.te. pe.formance.in the.PVT than track and fie.d athle.e. and controls. The.e.be.we.n-group diffe.e.ce. we.e.not modulate. by the.spe.d de.ands of the.task. Conclusion： The.major nove. finding of this re.e.rch points to a positive.re.ationship be.we.n sport participation and vigilance.pe.formance.during childhood. We.discuss our re.ults in te.ms of the.diffe.e.t hypothe.e. put forward in the.lite.ature.to e.plain the.re.ationship be.we.n re.ular e.e.cise.and cognitive.fimctioning： the.＂cardiovascular fitne.s＂ and the.＂cognitive.compone.t skills＂ hypothe.e..2018 Publishe. by e.se.ie. B.V. on be.alf of Shanghai Unive.sity of Sport. This is an ope. acce.s article.unde. the.CC BY-NC-ND lice.se. （http：//***/lice.se./by-nc-nd/4.0/）.

关键词： Childhood Cognition Cognitive.skills Physical activity Physical e.e.cise Sustaine. atte.tion

Timing of bre.ding as a de.e.minant of ne.t succe.s of the.vulne.able.Che.tnut Se.de.te.(Sporophila cinnamome.)in grasslands of southe.n South Ame.ica

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Avian Re.e.rch 2023年第1期14卷 126-135页

作者： Jonas rafael Rodrigue. Rosoni Carla Sue.te.aray Fontana Caio JoséCarlos Programa de.Pós-Graduacão e. Biologia Animal Departamento de ZoologiaUniversidade Federal do Rio Grande do SulUFRGSAvenida Bento Gonçalves950091501-970Porto AlegreRio Grande do SulBrazil Laboratório de.Ornitologia Museu de Ciências e TecnologiaPrograma de Pós-Graduacão em Ecologia e Evolucão da BiodiversidadePontifícia Universidade Católica do Rio Grande do SulPUCRSAvenida Ipiranga668190619-900Porto AlegreRio Grande do SulBrazil De.artame. to de.e.ologia Universidade Federal do Rio Grande do SulUFRGSAvenida Bento Gonçalves950091501-970Porto AlegreRio Grandedo SulBrazil

The.bre.ding traits of Sporophila se.de.te.s have.be.n re.ative.y we.l studie. in re.e.t ye.rs;ne.e.the.e.s,a group of te. spe.ie. in the.ge.us,known as southe.n capuchinos,re.ain *** is the.case.with Che.tnut Se.de.te.(Sporophila cinnamome.),a spe.ie. vulne.able.to e.tinction,which bre.ds in the.grasslands of southe.st South Ame.ica and,afte. re.roduction,migrate. towards the.Ce.rado re.ion in ce.tral ***,we.inve.tigate. bre.ding e.ology and calculate. ave.age.clutch size.productivity,the.se. ratio of ne.tlings,and e.timate. ne.t *** we.te.te.(1)whe.he. the.e.is a re.ationship be.we.n the.numbe. of active.ne.ts and e.vironme.tal variable.,(2)whe.he. the.ne.tling se. ratio de.iate. from the.1:1 ratio,(3)whe.he. clutch size.varie. be.we.n bre.ding se.sons,and(4)whe.he. the.ne.t succe.s is re.ate. to starting date.ne.t age.plant support,ne.t he.ght from the.ground,and clutch *** two bre.ding se.sons(Octobe.-March 2018-2020),we.monitore. 98 *** ge.e.ate. survival mode.s with five.inte.acting covariate. to asse.s the.survival of the.*** re.orde. the.e.tire.bre.ding pe.iod for Che.tnut Se.de.te.,which was e.timate. to be.4.6 months,similar to othe. migratory *** size.did not diffe. be.we.n bre.ding *** se. ratio of ne.tlings was not significantly diffe.e.t from the.1:1 *** succe.s was 31%,and pre.ation was the.le.ding cause.of unsucce.sful ne.ts(83%).The.daily survival rate.was 0.95±*** main pre.ictor of ne.t survival was the.covariate.starting *** findings,adde. to othe. aspe.ts of the.spe.ie.’natural history de.cribe. he.e.may he.p illuminate.the.e.ology and be.avior of Che.tnut Se.de.te. and othe. southe.n e.dange.e. capuchinos,and grassland-de.e.de.t spe.ie. of South Ame.ica.

关键词： Brood parasitism Clutch size Ne.tropical grassl ands Ne.t age Ne.t pre.ation Ne.t survival

The.mal and Me.hanical Prope.tie. of The.moplastic Starch and Poly(Vinyl Alcohol-Co-e.hyle.e.Ble.ds

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Journal of Re.e.able.Mate.ials 2019年第3期7卷 245-252页

作者： Ana Clara Lancarovici Alve. rafael Grande.Antonio José Fe.ix Carvalho De.artme.t of Mate.ials e.gine.ring Sao Carlos School of EngineeringUniversity of Sao PauloAv.Joao Dagnone110013563-120Sao Carlos-SP-Brazil

The.inte.e.t in the.moplastic starch(TPS)as a substitute.mate.ial to re.lace.conve.tional the.moplastics continue. e.pe.ially due.its biode.radability,availability,low cost and be.ause.it is obtaine. from re.e.able.***,its poor me.hanical prope.tie. and its high se.sitivity to humidity have.limite. its use.in se.e.al ***,the.copolyme. poly(e.hyle.e.co-vinyl alcohol)(e.OH),with two diffe.e.t e.hyle.e.conte.ts,27 and 44 mol%we.e.ble.de. with TPS by e.trusion in orde. to ove.come.the.e.*** obtaine. ble.ds we.e.characte.ize. by the.mogravime.ric analysis(TGA),diffe.e.tial scanning calorime.ry(DSC),me.hanical te.sile.te.ting,Scanning e.e.tron Microscopy(Se.)and moisture.absorption *** addition of e.OH copolyme. did not significantly change. the.the.mal stability of TPS,howe.e. it incre.se. the.te.sile.stre.gth in 65%whe. compare. to *** morphology of the.ble.ds did not showe. two distinct phase.,an indication of miscibility or partial miscibility of the.compone.ts.A de.re.se.of moisture.absorption was obtaine. by the.addition of e.OH and is more.pronounce. for the.e.OH with 44% of e.hyle.e.

关键词： The.moplastic starch e.OH polyme. ble.ds the.mal prope.tie. of polyme.s me.hanical prope.tie. of polyme.s

Product de.e.opme.t cost e.timation through ontological mode.s-a lite.ature.re.ie.

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Journal of Manage.e.t Analytics 2019年第2期6卷 209-229页

作者： rafael Voltolini Kaio Vasconce.os Milton Borsato Marghe.ita Pe.uzzini Programa de.Pós-Graduação e. e.ge.haria Me.ânica e.de.Mate.iais(PPGe.) Universidade Tecnológica Federal do Paraná(UTFPR)CuritibaBrasil Dipartime.to di Inge.ne.ia“e.zo Fe.rari”(DIe.) Universitàdegli Studi di Modena e Reggio Emilia(UNIMORE)ModenaItaly

The.e.rly stage. of product de.e.opme.t are.characte.ize. by *** must de.l with challe.ge. that arise.une.pe.te.ly in an agile.and re.ponsive.*** information syste.s base. on ontological mode.s are.a promising approach to capture.knowle.ge.and rationale.of domain spe.ialists,e.the. for de.ision making or knowle.ge.*** pre.e.t study pre.e.ts a bibliome.ric analysis on the.use.of ontologie. in product de.e.opme.t for cost *** ide.tifie. tre.ds and re.e.rch opportunitie. that can orie.t future.*** a ge.e.al se.rch in scie.tific database.,31 article. we.e.found and se.e.te. base. on crite.ia e.tablishe. using the.Proknow-C *** indicate.that the.e.are.se.e.al possibilitie. for solutions using ontological and hybrid,transdisciplinary *** inte.lige.t syste.s is not only promising but is also challe.ging as a ne. and re.l transdisciplinary re.e.rch are. of inte.e.t.

关键词： Proknow-C product de.e.opme.t ontology cost re.ie.

De.ore.tation and fragme.tation tre.ds of se.sonal dry tropical fore.t in e.uador: impact on conse.vation

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Fore.t e.osyste.s 2021年第3期8卷 615-627页

作者： Carlos A.Rivas JoséGue.re.o-Casado rafael M.Navarro-Ce.illo Instituto de.Cie.cias Básicas Universidad Técnica de ManabíPortoviejoManabíEcuador De.artme.t of Fore.t e.gine.ring Laboratory of DendrochronologySilviculture and Global Change–DendrodatLab–ERSAFUniversity of CordobaCampus de RabanalesCrta.IVkm.396E-14071 CordobaSpain De.artame.to de.Me.icina Ve.e.inaria Facultad de Ciencias VeterinariasUniversidad Técnica de ManabíPortoviejoManabíEcuador De.artme.t of Zoology University of CordobaCampus de Rabanales14071 CordobaSpain

Background:Fragme.tation and de.ore.tation are.one.of the.gre.te.t thre.ts to fore.ts,and the.e.proce.se. are.of e.e. more.conce.n in the.tropics,whe.e.the.se.sonal dry fore.t is possibly one.of the.most thre.te.e. e.osyste.s with the.le.st re.aining surface.***:The.de.ore.tation and fragme.tation patte.ns that had occurre. in e.uadorian se.sonal dry fore.ts be.we.n 1990 and 2018 we.e.ve.ifie.,while.ge.graphic information syste.s and land cove. shape. provide. by the.e.uadorian Ministry of the.e.vironme.t we.e.e.ploye. to classify and e.aluate.thre. type. of se.sonal dry fore.ts:de.iduous,se.i-de.iduous,and *** study are. was te.se.late. into 10 km2 he.agons,in which six fragme.tation parame.e.s we.e.me.sure.:numbe. of patche.,me.n patch size.me.ian patch size.total e.ge.e.ge.de.sity and re.icular fragme.tation inde.(RFI).The.RFI was also me.sure. both outside.and inside.prote.te. natural are.s(unprote.te.,national prote.te. are.s and prote.te. fore.t).More.ve.,the.are.s with the.be.t and worst conse.vation status,conne.tivity and risk of disappe.rance.value. we.e.ide.tifie. by me.ns of a Ge.is-Ord Gi*statistical ***:The.de.ore.tation of se.sonal dry fore.ts affe.te. 27.04%of the.original surface.are. still re.aining in 1990,with an annual de.ore.tation rate.of−1.12%be.we.n 1990 and *** RFI has incre.se. by 11.61%as a re.ult of the.fact that small fragme.ts of fore.t have.te.de. to disappe.r,while.the.large.fragme.ts have.be.n fragme.te. into smalle. *** se.i-de.iduous fore.t had the.highe.t le.e.s of fragme.tation in *** thre. cate.orie. of prote.tion had significantly diffe.e.t le.e.s of fragme.tation,with lowe. RFI value. in national prote.te. are.s and gre.te. value. in prote.te. ***:The.se.sonal dry fore.t is fragme.ting,de.ore.ting and disappe.ring in some.*** incre.se. prote.tion and conse.vation of the.e.uadorian se.sonal dry fore.t is,the.e.ore.ne.e.sary owing to the.fact that not all prot

关键词： De.iduous fore.t Se.i-de.iduous fore.t Re.nant fore.t Patch isolation Habitat loss Prote.te. are.s

e.gine.ring magne.ic nanostructure. with inve.se.hyste.e.is loops

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Nano Re.e.rch 2016年第8期9卷 2347-2353页

作者： Be.triz Mora Nastassia Soriano Carolina Re.ondo Albe.to Arte.he.David Navas rafael Morale. Dpto. de.Quimica-Fisica Universidad del Pais Vasco UPWEHU 48940 Leioa Spain IFIMUP-IN and De.t. Fisica e.Astronomia Universidade do Porto 4169007 Porto Portugal Dpto. de.Qulmica-Ffsica & BCMate.ials Universidad del Pals Vasco UPV/EHU 48940 Leioa Spain IKe.BASQUe Basque Foundation for Science 48011 Bilbao Spain

Top-down lithography te.hnique. allow the.fabrication of nanostructure. e.e.e.ts with nove. spin configurations, which provide.a ne. route.to e.gine.r and manipulate.the.magne.ic re.ponse.of se.sors and e.e.tronic de.ice. and unde.stand the.role.of fundame.tal inte.actions in mate.ials scie.ce. In this study, shallow nanostructure.patte.ne. thin films we.e.de.igne. to pre.e.t inve.se.magne.ization curve., i.e., an anomalous magne.ic me.hanism characte.ize. by a ne.ative.coe.civity and ne.ative.re.ane.ce. This proce.ure.involve. a me.hod for manipulating the.spin configuration that yie.de. a ne.ative.coe.civity afte. the.patte.ning of a single.mate.ial laye.. Patte.ne. NiFe.thin films with tre.ch de.ths be.we.n 15%-25% of the.total film thickne.s e.hibite. inve.se.hyste.e.is loops for a wide.angular range.of the.applie. fie.d and the.tre.ch axis. A mode. base. on two e.change.couple. subsyste.s accounts for the.e.pe.ime.tal re.ults and thus pre.icts the.conditions for the.appe.rance.of this magne.ic be.avior. The.findings of the.study not only advance.our unde.standing of patte.ning e.fe.ts and confine. magne.ic syste.s but also e.able.the.local de.ign and control of the.magne.ic re.ponse.of thin mate.ials with pote.tial use.in se.sor e.gine.ring.

关键词： magne.ic nanostructure. magne.ic patte.ning e.fe.ts inve.te. loops ne.ative.coe.civity ne.ative.re.ane.ce

Valorization of Solid Waste.Re.ove.y in an Institution of Highe. e.ucation

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Gre.n and Sustainable.Che.istry 2018年第2期8卷 180-189页

作者： Nora e. Mungu&iacute.a &Aacute.nge.a M. D&iacute.az Luis e. Ve.azque. rafael Pe.e. Javie. e.que. David S. Ze.e.a Sustainability Graduate.Program University of Sonora Hermosillo M&eacute xico

One.of the.bigge.t challe.ge. for organizations, citie. and countrie. is waste.manage.e.t. Curre.tly, 1.3 million tons of solid waste. are.ge.e.ate. in the.citie. and by 2025 it is e.timate. that this volume.will incre.se.up to 2.2 billion tons. Conside.ing this, it is cle.r that strate.ie. for the.re.uction of waste.ge.e.ation are.ne.de.. In orde. to achie.e.this arduous and critic task change. in e.ucation, culture.and public policy are.re.uire. and one.of the.strate.ie. that e.e.ge.as one.of the.most e.fe.tive.is the.“ze.o waste. programs. This pape. shows the.foundation of a ze.o waste.program base. on pre.ious and succe.sful e.pe.ie.ce. in institutions of highe. e.ucation. It pre.e.ts the.characte.ization and quantification of waste. as we.l as the.valorization of it and pote.tial e.vironme.tal and e.onomic be.e.its of the.imple.e.tation of this kind of programs in highe. e.ucation institutions. Re.ults show that re.uction and valorization of waste.ge.e.ation is possible.in acade.ic se.tors while.othe. outcome. e.e.ge. such as the.ge.e.ation of human capital for the.imple.e.tation of this kind of programs in diffe.e.t se.tors of socie.y and, in that way, contribute.in the.transition towards sustainable.de.e.opme.t.

关键词： Ze.o Waste Programs Valorization Highe. e.ucation Institutions Solid Waste

Appropriate.se.rch te.hnique. to e.timate.We.bull function parame.e.s in a Pinus ***

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Journal of Fore.try Re.e.rch 2021年第6期32卷 2423-2435页

作者： Lais Alme.da Araujo rafael Me.ali Olive.ra Mario Dobne. Jr Carolina Souza Jarochinskie.Silva Lucas Re.e.de.Gomide De.artme.t of Fore.t Scie.ce. Federal University of LavrasLavrasMinas GeraisBrazil De.artme.t of Agriculture Biodiversity and ForestsFederal University of Santa CatarinaCuritibanosSanta CatarinaBrazil

The.We.bull function,a continuous probability distribution,is wide.y use. for diame.e. distribution mode.ling,in which parame.e. e.timation pe.formance.is affe.te. by stand attribute. and fitting *** We.bull cumulative.distribution function is nonline.r,and classical fitting me.hods may provide.a not optimal *** the.use.of artificial inte.lige.ce.by me.ahe.ristics is re.sonable.for this optimisation ***,aime. and compare.(1)the.me.ahe.ristics ge.e.ic algorithm and simulate. anne.ling pe.formance.ove. the.mome.t and pe.ce.tile.me.hods;(2)the.hybrid strate.y me.ging the.me.ahe.ristics te.te. and the.pe.ce.tile.me.hod and,(3)the.me.ahe.ristics fitne.s functions unde. basal are. and de.sity e.rors.A long-te.m e.pe.ime.t in a Pinus tae.a stand subje.te. to crown thinning was *** to our findings,all me.hods have.a similar pe.formance.inde.e.de.t of the.thinning re.ime. and *** patte.n of the.e.timate. parame.e.s te.ds to be.acce.table.as b incre.se. ove. time.and c incre.se. afte. ***,our findings sugge.t that me.hods base. on me.ahe.ristics have.a highe. pre.ision than classical me.hods for e.timating We.bull *** to the.classification te.t,the.me.hods that involve. simulate. anne.ling stood *** hybrid me.hod involving this me.ahe.ristic also stood out,with accurate.*** me.hods showe. the.poore.t pe.formance.and we.the.e.ore.sugge.t the.use.of simulate. anne.ling due.to its faste. proce.sing time.and high-quality solution.

关键词： Fore.t manage.e.t Diame.e.s distribution We.bull function Ge.e.ic algorithm Simulate. anne.ling