BACKGROUND:With the objective of developing a locally- produced radioactive stent,the present study used in vivo animal experiments to explore apoptosis of proliferative smooth muscle cells resulting from facilitation...
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BACKGROUND:With the objective of developing a locally- produced radioactive stent,the present study used in vivo animal experiments to explore apoptosis of proliferative smooth muscle cells resulting from facilitation of the expression of genes caused byγ-radiation in order to prevent bile duct *** therefore explored the effects and significance ofγ-radiation on the activity of caspase-3,Fas and Bcl-2.genes in apoptosis of proliferative smooth muscle cells in the bile duct walls of dogs. METHODS:Twelve dogs were randomly divided into 2.groups(6 in each group).A postinjury bile duct stenosis model was established and radioactive 103 Pd( 103 palladium) or ordinary bile duct stents were implanted into the bile *** staining,RT-PCR and immunohistochemistry were used to detect the proliferation and apoptosis of bile duct smooth muscle cells in proliferative endomembrane and the expression of related caspase-3,Bcl-2.and Fas genes. RESULTS:The expression of caspase-3 and Fas genes in the bile duct tissues of dogs with radioactive stents was higher than that of dogs with ordinary *** was significant apoptosis of proliferative smooth muscle cells in the bile *** expression of the Bcl-2.gene in the bile duct tissues of dogs with radioactive stents was lower than that in those with ordinary *** was significant apoptosis of proliferative smooth muscle cells in the dogs with low Bcl-2.gene expression. CONCLUSIONS:radiation increases the activity of caspase-3 and Fas genes and is associated with apoptosis. The radioactive 103 Pd stent may facilitate apoptosis of proliferative smooth muscle cells in the bile ducts of dogs by activating these *** Bcl-2.gene expression level is correlated with the occurrence of apoptosis and the radiosusceptibility of cells.
<正>The problems and fabrication difficulties with theconventional edge-emitted LDs,VCSELs and LEDswere *** transverse coupled large opticalcavity LDs,longitudinal coupled VCSELs and highefficiency and ultrahigh bri...
<正>The problems and fabrication difficulties with theconventional edge-emitted LDs,VCSELs and LEDswere *** transverse coupled large opticalcavity LDs,longitudinal coupled VCSELs and highefficiency and ultrahigh brightness LEDs with multi-active region structure were *** andexperiments indicated that these novel LDs and LEDswere of excellent performance and applicationprospects.
The objective was to isolate,elucidate and analyze the bioactive chemicals from the tuber of Arundina graminifolia(Dai Monority Medicine).The compounds were extracted by 95%alcohol and isolated by column chromatograph...
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The objective was to isolate,elucidate and analyze the bioactive chemicals from the tuber of Arundina graminifolia(Dai Monority Medicine).The compounds were extracted by 95%alcohol and isolated by column chromatography on silica gel,Sephedax LH-2. and *** structures were determined by UV,IR,NMR and MS spectra.
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