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International study of the Complex Stress Reaction Syndrome:Implications for transdiagnostic clinical practice

World Journal of Psychiatry 2023年第10期13卷 803-815页

作者： Sari Goldstein Ferber Aron Weller Adele M Hayes Tracy D Vannorsdall Yaroup Ajlouni Mo'nes Qudah Gil Zalsman Gal Shoval Tommaso Benedetto Jannini racquel fiedler Lily X Chen Danielle R Shayani Elin Kachuki Dory Dana Stolowicz-Melman Connor Evans Megan Trow Giorgio Di Lorenzo Rodolfo Rossi Department of Psychological and Brain Sciences University of DelawareNewarkDE 19716United States Department of Psychology Bar Ilan UniversityRamat Gan 5290002Israel Department of Psychology and The Gonda Brain Research Center Bar Ilan UniversityRamat Gan 5290002Israel Department of Psychiatry and Behavioral Sciences Department of NeurologyThe Johns Hopkins University School of MedicineBaltimoreMD 21287United States Jordan Health Aid-International Amman 1234Jordan Geha Mental Health Center Petah TiqvaIsrael and Faculty of MedicineTel Aviv UniversityRamat Aviv 6997801Israel Division of Molecular Imaging and Neuropathology Department of PsychiatryColumbia UniversityNew YorkNY 10032United States Department of Neuroscience Princeton UniversityPrincetonNJ 08544United States Department of Systems Medicine Tor Vergata University of RomeRome 00133Italy UNSW School of Psychology UNSW SydneySydney 2052Australia Department of Biology Pacific UniversityForest GroveOR 97116United States Oregon Chapter of Fulbright Association OregonOR 97045United States Department of Systems Medicine Tor Vergata University of RomeRome 00179Italy IRCCS Fondazione Santa LuciaRome 00179Italy

BACKGROUND The debate regarding diagnostic classification systems in psychiatry(categorial vs dimensional systems)has essential implications for the diagnosis,prevention and treatment of stress *** previously found a unique pattern of stress reaction in a study executed during the coronavirus disease 2019 pandemic using large representative samples in two countries,and termed it the Complex Stress Reaction Syndrome(CSRS).AIM To investigate CSRS,Type A(psychiatric symptoms,spanning anxiety,depression,stress symptoms,and posttraumatic stress disorder(PTSD)),with or without long-coronavirus disease(COVID)residuals(CSRS,Type B,neuropsychiatric symptoms spanning cognitive deficits and fatigue,excluding systemic symptoms).Our two-tailed hypothesis was that CSRS is a condition related to an unrecognized type of stress reaction in daily life in the general population(Type A)or that it is related to the severe acute respiratory syndrome coronavirus 2 infection and its long-COVID residuals(Type B).METHODS 977 individuals in four continents(North America,Europe,Australia and the Middle East)completed the online study questionnaire in six languages using the Qualtrics *** study was managed by six teams in six countries that promoted the study on social *** questionnaire assessed anxiety,depression,stress symptoms and PTSD(CSRS,Type A),cognitive deficits and fatigue(CSRS,Type B).The data were analyzed using Proportion Analyses,Multivariate Analysis of Co-Variance(MANCOVA),linear regression analyses and validated clinical cutoff *** The results of the Proportion Analyses showed that the prevalence of 4 symptoms spanning anxiety,depression,stress symptoms,and PTSD was significantly higher than the most prevalent combinations of fewer symptoms across 4 continents,age groups,and *** supports the transdiagnostic argument embedded in the CSRS(Type A).The same pattern of results was found in infected/recovered *** prevalence of the

关键词： Transdiagnostic Complex Stress Reaction Syndrome Stress reactivity Affective disorders Debate in psychiatry

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