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The new kid on the block in insect pest management:sprayable RNAi goes commercial

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Science China(Life Sciences) 2024年第8期67卷 1766-1768页

作者： Junjie Yan Ralf Nauen Stuart Reitz Andrei Alyokhin Jiang Zhang David Mota-Sanchez Yonggyun Kim Subba Reddy Palli Silvia I.Rondon Brian A.Nault Juan Luis Jurat-Fuentes Michael S.Crossley William E.snyder Angharad M.R.Gatehouse Myron P.Zalucki Bruce E.Tabashnik Yulin Gao State Key Laboratory for Biology of Plant Disease and Insect Pests Institute of Plant ProtectionChinese Academy of Agricultural SciencesBeijing 100193China Bayer AG Crop Science DivisionR&DPest ControlMonheim 40789Germany Department of Crop and Soil Science Oregon State UniversityOntario 97914USA School of Biology and Ecology University of MaineOrono 04469USA Shenzhen Branch Guangdong Laboratory of Lingnan Modern AgricultureKey Laboratory of Synthetic BiologyMinistry of Agriculture and Rural AffairsAgricultural Genomics Institute at ShenzhenChinese Academy of Agricultural SciencesShenzhen 518000China Department of Entomology Michigan State UniversityEast Lansing 48864USA Department of Plant Medicals Andong National UniversityAndong 36729Republic of Korea Department of Entomology University of KentuckyLexington 40503USA Oregon State University Oregon Integrated Pest Management CenterCorvallis 97838USA Department of Entomology Cornell UniversityCornell AgriTechGeneva 14456USA Department of Entomology and Plant Pathology University of TennesseeKnoxville 37996USA Department of Entomology and Wildlife Ecology University of DelawareNewark 19716USA Department of Entomology University of GeorgiaAthensGeorgia 30602USA School of Natural and Environmental Sciences Newcastle UniversityNewcastle upon TyneNE17RUUK School of the Environment University of QueenslandBrisbane 4072Australia Shandong Engineering Research Center for Environment-Friendly Agricultural Pest Management College of Plant Health and MedicineQingdao Agricultural UniversityQingdao 266109China Department of Entomology University of ArizonaTucson 85721USA National Center of Excellence for Tuber and Root Crop Research Chinese Academy of Agricultural SciencesBeijing 100081China

Insect pest damage to crops is a threat to global food security(Tilman et al.,2011).Climate change,the evolution of insecticide resistance,and the phasing out of insecticides due to environmental and safety concerns exacerbate this *** urgently need safe and effective crop protection tools to sustainably generate yields that meet ever-increasing global demand.

关键词： crops damage pest

Trilayer anisotropic structure versus randomly oriented structure in heart valve leaflet tissue engineering

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Bio-Design and Manufacturing 2023年第4期6卷 423-438页

作者： Yuriy snyder Soumen Jana Department of Bioengineering University of MissouriColumbiaMO 65211USA

It has been hypothesized that leaflet substrates with a trilayer structure and anisotropicmechanical properties could be useful for the production of functional and long-lasting tissue-engineered *** investigate the influence of the anisotropic structural and mechanical characteristics of a substrate on cells,in this study,we electrospun trilayer anisotropic fibrous substrates and randomly oriented isotropic fibrous substrates(used as controls)from polycaprolactone ***,the random substrates had higher radial and lower circumferential tensile properties than the trilayer substrates;however,they had similar flexural *** valvular interstitial cells cultured on both substrates produced random and trilayer cell-cultured constructs,*** trilayer cell-cultured constructs had more anisotropic mechanical properties,17%higher cellular proliferation,14%more extracellular matrix(i.e.,collagen and glycosaminoglycan)production,and superior gene and protein expression,suggesting that more cells were in a growth state in the trilayer constructs than in the random ***,the random and radial layers of the trilayer constructs had more vimentin,collagen,transforming growth factor-beta 1(TGF-ß1),transforming growth factor-beta 3(TGF-ß3)gene expression than in the circumferential layer of the *** study verifies that the differences in structural,tensile,and anisotropic properties of the trilayer and random substrates influence the characteristics of the cells and ECM in the constructs.

关键词： Heart valve leaflet Trilayer Tissue engineering Fiber Electrospinning

No country is an island in regulating food safety:How the WTO monitors Chinese food safety laws through the Trade Policy Review Mechanism(TPRM)

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Journal of Integrative Agriculture 2015年第11期14卷 2142-2156页

作者： Francis snyder Northwest A&F University School of Transnational Law Peking University Shenzhen Graduate School College of Europe

Established within the framework of the World Trade Organization （WTO）, the Trade Policy Review Mechanism （TPRM） reviews periodically the trade policies of all WTO Members. The review includes many aspects of food safety regulation. China＇s trade policy is reviewed every two years. This paper analyses in detail the reviews of China＇s trade policy in 2006, 2008, 2010, 2012 and 2014. It focuses in particular on food safety laws and types of standards, alignment of domestic standards with international standards, the role of different domestic institutions, transparency and notification of food safety measures under the WTO agreements on Sanitary and Phytosanitary Measures （SPS） and on Technical Barriers to Trade （TBTAgreement）, import and export, and geographical indications （GIs）. It concludes that the WTO TPRM can contribute, within its mandate, to reform of Chinese food safety laws and improvement of food safety in China. it notes that China has already undertaken substantial reforms of its system for regulating food safety. It recommends that China should continue to participate actively in the TPRM, follow its own path with regard to alignment and learn selectively from other WTO Members.

关键词： food safety food standards public health consumer welfare China Chinese food safety laws World Trade Organization WTO law Trade Policy Review Mechanism (TPRM) SPS Agreement TBT Agreement

睾酮治疗性腺功能减退症男性患者对骨折风险影响的临床研究

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中国临床药理学杂志 2024年第5期40卷 731-731页

作者： snyder P J BAUER D C ELLENBERG S S 孟海峰

男性性腺功能减退症患者的睾酮治疗可以改善骨密度和骨质量,但需要足够大的样本和足够长的持续时间来确定睾酮对骨折发生率的影响。

关键词：骨折发生率性腺功能减退症骨质量骨折风险睾酮治疗骨密度持续时间男性患者

Role of simple biomarkers in predicting fibrosis progression in HCV infection

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World Journal of Gastroenterology 2010年第45期16卷 5710-5715页

作者： Rajasekhara R Mummadi John R Petersen Ned snyder Division of Gastroenterology and Hepatology Department of Internal MedicineUniversity of Texas Medical BranchHoustonTX 77025United States Department of Pathology University of Texas Medical BranchHoustonTX 77025United States Department of Gastroenterology and Hepatology Kelsey Seybold Clinic2727 W. HolcombeHoustonTX 77025United States

AIM: To examine the accuracy of the aspartate aminotransferase (AST)/Platelet Ratio Index (APRI) and FIB-4, in predicting longitudinal changes in liver histology in hepatitis C virus (HCV) ***: Patients that underwent repeat liver biopsies at least 1 year apart from 1999 to 2007 were identified. Liver fibrosis was staged on needle core biopsies evaluated by a single expert liver pathologist. Only laboratory values within 3 mo of the liver biopsies were ***: Thirty-six patients met the inclusion criteria with 50% stage 1 on initial biopsy, 25% stage 2, and 22% stage 3. Nineteen of 36 (53%) had progression of fibrosis on repeat biopsies, while 16 (44%) showed no change in stage, and one (3%) showed improvement. Patients that showed progression of fibrosis had significantly higher alanine aminotransferase and aspartate aminotransferase levels than the group that did not show progression. A significant correlation was seen between change in stage of fibrosis and change in APRI (r2 = 0.39, P = 0.00001) and a change in FIB-4 (r2 = 0.31, P = 0.00004). A change in APRI (ΔAPRI) of 0.18 had 80% positive predictive value (PPV) and 67% nega- tive predictive value (NPV) for progression of fibrosis. A change in FIB-4 (ΔFIB-4) of 0.39 had 75% PPV and 75% NPV for predicting progression of fibrosis. CONCLUSION: ΔAPRI and ΔFIB-4 parallel changes in fibrosis progression, and could be useful tools for clinicians in following patients with active chronic HCV infection.

关键词： Hepatitis C Liver fibrosis Liver biopsy Biomarkers

Chronic hepatitis C is a common associated with hepatic granulomas

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World Journal of Gastroenterology 2008年第41期14卷 6366-6369页

作者： Ned snyder Juan G Martinez Shu-Yuan Xiao Department of Internal Medicine University of Texas Medical Branch Galveston Texas 77555-0764 United States Department of Pathology University of Texas Medical Branch Galveston Texas 77555-0588 United States

AIM： To determine the most frequent etiologies of hepatic epithelioid granulomas, and whether there was an association with chronic hepatitis C virus （HCV）. METHODS： Both a retrospective review of the pathol- ogy database of liver biopsies at our institution from 1996 through 2006 as well as data from a prospective study of hepatic fibrosis markers and liver biopsies from 2003 to 2006 were reviewed to identify cases of hepatic epithelioid granulomas. Appropriate charts, liver biopsy slides, and laboratory data were reviewed to determine all possible associations. The diagnosis of HCV was based on a positive HCV RNA. RESULTS： There were 4578 liver biopsies and 36 （0.79%） had at least one epithelioid granuloma. HCV was the most common association. Fourteen patients had HCV, and in nine, there were no concurrent condi- tions known to be associated with hepatic granulomas. Prior interferon therapy and crystalloid substances from illicit intravenous injections did not account for the finding. There were hepatic epithelioid granulomas in 3 of 241 patients （1.24%） with known chronic HCV enrolled in the prospective study of hepatic fibrosis markers. CONCLUSION： Although uncommon, hepatic granu- Iomas may be part of the histological spectrum of chronic HCV. When epithelioid granulomas are found on the liver biopsy of someone with HCV, other clini- cally appropriate studies should be done, but if nothing else is found, the clinician can be comfortable with an HCV association.

关键词： Hepatitis C Liver Granulomas Liver biopsy

Calculation and Simulation of Evapotranspiration of Applied Water

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Journal of Integrative Agriculture 2012年第3期11卷 489-501页

作者： Richard L snyder Shu Geng Morteza Orang Sara Sarreshteh Department of Land Air and Water Resources University of California Davis CA 95616 USA School of Environment and Energy Shenzhen Graduate School Peking University Shenzhen 518055 P.R.China Department of Plant Sciences University of California Davis CA 95616 USA California Department of Water Resources Division of Statewide Integrated Water Management Water Use and Efficiency SacramentoCA 94236 USA

The University of California, Davis and the California Department of Water Resources have developed a weather generator application program “SIMETAW” to simulate weather data from climatic records and to estimate reference evapotranspiration （ETo） and crop evapotranspiration （ETc） with the generated simulation data or with observed data. A database of default soil depth and water holding characteristics, effective crop rooting depths, and crop coefficient （Kc） values to convert ETo to ETc are input into the program. After calculating daily ETc, the input and derived data are used to determine effective rainfall and to generate hypothetical irrigation schedules to estimate the seasonal and annual evapotranspiration of applied water （ETaw）, where ETaw is the net amount of irrigation water needed to produce a crop. in this paper, we will discuss the simulation model and how it determines ETaw for use in water resources planning.

关键词： weather generator water balance crop water requirements water resource planning crop coefficient

A cautionary note on decadal sea level pressure predictions from GCMs

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Advances in Climate Change Research 2018年第1期9卷 43-56页

作者： Stefan LIESS Peter K.snyder Arjun KUMAR Vipin KUMAR Department of Earth Sciences University of MinnesotaMinneapolis MN 55455USA Department of Soil Waterand ClimateUniversity of MinnesotaSt.Paul MN 55108USA Computer Science&Engineering University of MinnesotaMinneapolis MN 55455USA

A comparison of sea level pressure(SLP)trends in a subset of seven Coupled Model Intercomparison Project(CMIP)phase 5 general circulation models(GCM),namely decadal simulations with CCSM4,CanCM4,MPI-ESM-LR,FGOALS-g2,MIROC4h,MIROC5,and MRICGCM3,to their CMIP3 counterparts reveals an unrealistically strong forecast skill in CMIP3 models for trend predictions for 2001e2011 when using the 1979e2000 period to train the ***-winter SLP trends over five high-,mid-,and low-latitude zones were calculated over the 1979e2000 initialization period for each ensemble member and then ranked based on their performance relative to HadSLP2 *** same method is used to rank the ensemble members during the 2001e2011 *** CMIP3,17 out of 38 ensemble members retain their rank in the 2001e2011 hindcast period and 3 retain the neighboring ***,numbers are much lower in more recent CMIP5 decadal predictions over the similar 2001e2010 period when using the 1981e2000 period as initialization with the same number of *** periods were used for CMIP3 and CMIP5 because although the 1979e2000 initialization is widely used for CMIP3,CMIP5 decadal predictions are only available for 30-year *** conclusion to consider the forecast skill in CMIP3 predictions during 2001e2011 as unrealistic is corroborated by comparisons to earlier periods from the 1960s to the 1980s in both CMIP3 and CMIP5 ***,although the 2001e2011 CMIP3 predictions show statistically significant forecast skill,this skill should be treated as a spurious result that is unlikely to be reproduced by newer more accurate GCMs.

关键词： sea level pressure CMIP3 Coupled Model Intercomparison Project

Thermal conductivity of complex materials

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National Science Review 2019年第3期6卷 380-381页

作者： G.Jeffrey snyder Matthias T.Agne Ramya Gurunathan Department of Materials Science and Engineering Northwestern University

In the discussion and analysis of thermal properties (e.g. heat capacity, thermal conductivity) the Debye approximation is typically used to describe the collective behavior of lattice vibrations (phonons) in solid ma... 详细信息

关键词： Thermal conductivity of complex materials