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Two-Stent Strategy for Bifurcation Lesions in Percutaneous Transluminal Coronary Angioplasty: Real-World Evidence

World Journal of Cardiovascular Diseases 2024年第3期14卷 140-156页

作者： Dilip Kumar Amit Malviya Animesh Mishra rabin chakraborty Sanjeev S. Mukherjee Soumya Patra Arindam Pande Rana Rathor Roy Debopriyo Mondal Ashesh Halder Sumit Shanker Medica Superspecialty Hospital 127 Eastern Metropolitan Bypass Nitai Nagar Mukundapur Kolkata West Bengal India North Eastern Indira Gandhi Regional Institute of Health & Medical Sciences (NEIGRIHMS) Mawdiangdiang Shillong Meghalaya India

Background: Bifurcation lesions pose a high risk for adverse events after percutaneous coronary intervention (PCI). Evidence supporting the benefits of the two-stent strategy (2SS) for treating coronary bifurcation lesions in India is limited. This study aimed to evaluate the clinical outcomes of various 2SSs for percutaneous transluminal coronary angioplasty for bifurcation lesions in India. Materials and Methods: This retrospective, observational, multicentric, real-world study included 64 patients over 8 years. Data on demographics, medical history, PCI procedures, and outcomes were recorded. Descriptive statistics were computed using the SPSS software. Results: Patients (n = 64) had an average age of 65.3 ± 11.1 years, with 78.1% males. Acute coronary syndrome was reported in 18.8%, chronic stable angina in 40.6%, and unstable angina in 34.4% of participants. Two-vessel disease was observed in 98.4% of patients, and 99.4% had true bifurcation lesions. The commonly involved vessels were the left anterior descending artery (50%), left circumflex coronary artery (34.4%), and first diagonal artery (43.8%). Mean percent diameter stenosis was 87.2% ± 10.1%. The mean number of stents used was 2.00 ± 0.34. The 2SS techniques included the T and small protrusion (TAP) (39.1%), double kissing (DK) crush (18.8%), and the culotte techniques (14.1%). Procedural and angiographic success rate was 92.18%. Major adverse cardiovascular events at 1-year follow-up occurred in 7.8% of cases. Conclusion: The 2SS for bifurcation lesions showed favorable in-hospital and follow-up outcomes. Findings can serve as a resource for bifurcation angioplasty in India. Larger real-world studies with robust methodology are needed to validate these results.

关键词： Bifurcation Stenting Coronary Bifurcation Lesions Percutaneous

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Two-Stent Strategy for Bifurcation Lesions in Percutaneous Transluminal Coronary Angioplasty: Real-World Evidence

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World Journal of Cardiovascular Diseases（心血管病） 2024年第3期 140页

作者： Dilip Kumar Amit Malviya Animesh Mishra rabin chakraborty Sanjeev S. Mukherjee Soumya Patra Arindam Pande Rana Rathor Roy Debopriyo Mondal Ashesh Halder Sumit Shanker

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Mapping COVID-19 in India:Southern states at the forefront of new JN.1 variant

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Asian Pacific Journal of Tropical Medicine 2024年第1期17卷 1-3页

作者： rabin Debnath Arshdeep Singh Kushal Seni Anjali Sharma Viney Chawla Pooja A Chawla Department of Pharmaceutical Chemistry ISF College of PharmacyG.T RoadGhal KalanMogaPunjab142001India Department of Pharmaceutical Analysis ISF College of PharmacyG.T RoadGhal KalanMogaPunjab142001India University Institute of Pharmaceutical Sciences and Research Baba Farid University of Health SciencesFaridkotPunjabIndia

A new variant,JN.1,stemming from the omicron subvariant BA.2.86,garnered the attention of the World Health Organization(WHO)as a"variant of interest."Despite its rapid global spread,especially in the US,Canada,France,Singapore,Sweden[1],and the UK,JN.1 is considered to pose minimal *** vaccinations are believed to remain effective against *** WHO underscores the importance of maintaining immunization records amid co-occurring respiratory illnesses,and epidemiologists recommend monitoring hospitalizations,particularly in areas with low vaccination rates.

关键词： Canada Mapping spite

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应用改进的Morgan-Morgan-Finney模型评估土壤侵蚀易感性:以尼泊尔Kulekhani流域为例

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Journal of Resources and Ecology 2024年第1期15卷 182-196页

作者： THAPA rabin JOSHI Rajeev BHATTA Binod GHIMIRE Santosh 尼泊尔赫陀达农林大学林业学院尼泊尔Hetauda44107 尼泊尔乌达布尔农林大学自然资源管理学院尼泊尔UdayapurKatari56310

本研究旨在考察Kulekhani流域土地利用与土地覆盖(LULC)动态变化及土壤侵蚀情况,并对2000年至2020年不同LULC类别进行分析。研究结果显示,Kulekhani流域森林土地比例从2000年的60.72%上升至2010年的62.43%,2020年达到64.75%。水域面积... 详细信息

本研究旨在考察Kulekhani流域土地利用与土地覆盖(LULC)动态变化及土壤侵蚀情况,并对2000年至2020年不同LULC类别进行分析。研究结果显示,Kulekhani流域森林土地比例从2000年的60.72%上升至2010年的62.43%,2020年达到64.75%。水域面积有小幅增加,2000年占比为1.07%,2020年增加到1.08%。相应地,荒地面积从0.21%增至0.35%。相反,农业用地比例逐渐减少,2000年为38%,2010年为36.24%,2020年降至33.82%。使用改进的Morgan-Morgan-Finney模型估算土壤流失量显示,2000年到2010年期间,加权平均土壤流失量呈下降趋势,而2010年到2020年期间略微增加。计算得出的土壤流失值分别为2000年8.64 t ha^(-1)yr^(-1)、2010年7.12 t ha^(-1)yr^(-1)和2020年7.30 t ha^(-1)yr^(-1)。土壤侵蚀易感性图表明,2000年到2020年期间,非常低风险的土壤侵蚀区域有所增加,主要集中在森林地区,而农业区域则显示出低到中度的易感性。此外,荒地区域显示出中高度的土壤侵蚀易感性。为解决这些问题,建议未来的努力应包括在荒地地区进行造林计划,在农业区域实施保护耕作方式,并采取适当的道路稳定措施。

关键词：水泥沙土地利用土地覆盖坡度降雨量

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Diversity of Orchids in Terms of Their Distribution, Uses and Conservation in Annapurna Conservation Area of Nepal

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American Journal of Plant Sciences 2024年第6期15卷 422-440页

作者： Babu Lal Tiruwa Basu Dev Neupane rabin Kadariya Chiranjibi Prasad Pokheral Bijaya Pant National Trust for Nature Conservation (NTNC)-Annapurna Conservation Area Project (ACAP) Pokhara Nepal Central Department of Botany Tribhuvan University Kathmandu Nepal

The Annapurna Conservation Area (ACA), the first conservation area and the largest protected area (PA) in Nepal, is incredibly rich in biodiversity. Notwithstanding this, orchids in the ACA have not been explored enough yet thus making the need for ambitious research to be carried out. Previous study only included 81 species of orchids within ACA. This study aims to update the record of species and genera richness in the ACA. In total 198 species of orchids, belonging to 67 genera (40% and 62% of the total recorded orchid species and genera in Nepal) has been recorded in ACA. This represents an increase of 144% in species and 56% in genera over the previous data. Out of the 198 species, 99 were epiphytes, 6 were holomycotrophic and 93 were terrestrial. Among the 67 genera, Bulbophyllum (17) species were dominant, followed by Dendrobium (16), Herminium (10), Coelogyne, Plantanthera (9 each), Eria, Habenaria, Oberonia (8 each), Calanthe (7), and Liparis (6). Fifty-six species were found to be ornamentally significant and 85 species medicinally significant.

关键词： Orchids Annapurna Conservation Area Diversity Distribution Uses

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Hormone abuse in sports： the antidoping perspective

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Asian Journal of Andrology 2008年第3期10卷 391-402页

作者： Osquel Barroso Irene Mazzoni Olivier rabin Science Department World Anti-Doping Agency （WADA） Montreal Quebec H4Z 1B7 Canada

Since ancient times, unethical athletes have attempted to gain an unfair competitive advantage through the use of doping substances. A list of doping substances and methods banned in sports is published yearly by the World AntiDoping Agency （WADA）. A substance or method might be included in the List if it fulfills at least two of the following criteria： enhances sports performance; represents a risk to the athlete＇s health; or violates the spirit of sports. This list, constantly updated to reflect new developments in the pharmaceutical industry as well as doping trends, enumerates the drug types and methods prohibited in and out of competition. Among the substances included are steroidal and peptide hormones and their modulators, stimulants, glucocorticosteroids, β2-agonists, diuretics and masking agents, narcotics, and cannabinoids. Blood doping, tampering, infusions, and gene doping are examples of prohibited methods indicated on the List. From all these, hormones constitute by far the highest number of adverse analytical findings reported by antidoping laboratories. Although to date most are due to anabolic steroids, the advent of molecular biology techniques has made recombinant peptide hormones readily available. These substances are gradually changing the landscape of doping trends. Peptide hormones like erythropoietin （EPO）, human growth hormone （hGH）, insulin, and insulin-like growth factor Ⅰ （IGF-Ⅰ） are presumed to be widely abused for performance enhancement. Furthermore, as there is a paucity of techniques suitable for their detection, peptide hormones are all the more attractive to dishonest athletes. This article will overview the use of hormones as doping substances in sports, focusing mainly on peptide hormones as they represent a pressing challenge to the current fight against doping. Hormones and hormones modulators being developed by the pharmaceutical industry, which could emerge as new doping substances, are also discussed.

关键词： World Anti-Doping Agency doping hormone sport

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HEMOPHILIACS AND ACQUIRED IMMUNE DEFICIENCY SYNDROME

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中华医学杂志(英文版) 1985年第6期98卷 444-446页

作者：林田赵家琪 Bruce rabin Xian Medical College Xian Immunology Section Dongzhimen Hospital Beijing Division of Clinical Immunopathology School of Medicine University of Pittsburge USA

During the past few years, it has been found that hemophiliacs suffer increasingly from AIDS, year to year. The first case of hemophiliac AIDS was reported in the winter of 1981, eight cases were reported in 1982 and 12 in 1983. We studied CMV, EBV, HTLV, and EA titers (see page 442) in hemophiliacs, and found that hemophiliacs have much higher sensitivity to CMV and EBV than healthy controls (p<0.001). There was a significant difference between hemophiliacs without any AIDS symptoms and heallthy men. The relationship between hemophiliacs and AIDS, and the reasons for hemophiliac acquiring AIDS are discussed.

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Enhancement of MTBE Biodegradation by Fe3O4 Magnetic Particles

Enhancement of MTBE Biodegradation by Fe3O4 Magnetic Particl...

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作者： rabin Poudel 浙江工业大学

学位级别：硕士

Magnetic particles（MPs）have been rapidly applied to bioremediation of environmental *** the promising performance,magnetic particles are getting attention to enhancing biodegradation activity to treat the volatile organic compounds（VOCs）from contaminated *** reusability,reactivity,and biocompatibility properties of the magnetic particles reduce the current environmental *** particles（MPs）can enhance the biodegradation of the methyl tert-butyl ether（MTBE）in the batch *** effect of Fe

关键词： Volatile organic compound biodegradation methyl tert-butyl ether magnetic nanoparticles enhancement

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Impact of global climate change on stream low flows:A case study of the great Miami river watershed, Ohio, USA

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International Journal of Agricultural and Biological Engineering 2019年第1期12卷 84-95页

作者： Sabin Shrestha Suresh Sharma Rishabh Gupta rabin Bhattarai Civil and Environmental Program Youngstown State UniversityYoungstownOH 44555USA Department of Agricultural and Biological Engineering University of Illinois at Urbana-ChampaignUrbanaIL 61801USA

Climate change will profoundly affect hydrological processes at various temporal and spatial *** study is focused on assessing the alteration of water resources availability and low flows frequencies driven by changing climates in different time periods of the 21st *** study evaluates the adaptability of prevailing Global Circulation Models(GCMs)on a particular watershed through streamflow *** analysis was conducted in the Great Miami River Watershed,Ohio by analyzing historical and future simulated streamflow using 10 climate model outputs and the Soil and Water Assessment Tool(SWAT).The climate change scenarios,consisting of ten downscaled Coupled Model Intercomparision Project Phase 5(CMIP5)climate models in combination with two Representative Concentration Pathways(RCP 4.5 and RCP 8.5)were selected based on the correlation between observed records and model *** for three future periods,2016-2043,2044-2071 and 2072-2099,were independently analyzed and compared with the baseline period(1988-2015).Results from the average of ten models projected that 7-day low flows in the watershed would increase by 19%in the 21st century under both *** trend was also consistent for both hydrological(7Q10,1Q10)and biological low flow statistics(4B3,1B3).Similarly,average annual flow and monthly flows would also increase in future periods,especially in the *** flows simulated by SWAT in response to the majority of climate model projections showed a consistent increase in low flow ***,the flow estimates using the Max-Planck-Institute Earth System Model(MPI-ESM-LR)climate output resulted in the biological based low flows(4B3,1B3)decreasing by 22.5%and 33.4%under RCP 4.5 and 56.9%and 63.7%under RCP 8.5,respectively,in the future when compared to the baseline ***,the low flow ensemble from the 10 climate models for the 21st century seemed to be slightly higher than that of historical low flows.

关键词： climate change low flows SWAT climate models Great Miami River Watershed

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Comparative investigation towards machinability improvement in hard turning using coated and uncoated carbide inserts： part Iexperimental investigation

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Advances in Manufacturing 2018年第1期6卷 52-70页

作者： Ramanuj Kumar Ashok Kumar Sahoo Purna Chandra Mishra rabin Kumar Das School of Mechanical Engineering Kalinga Institute of Industrial Technology BhubaneswarOdisha 751024 India

The investigation of low cost uncoated andcoated carbide insert in the hard turning of hardened AISID2 steel （≥55 HRC） will definitely open up a new arena asan economical alternative suitable to industrial machiningsectors. Thus, this paper reports the comparative machin-ability assessment for the hard turning of AISI D2 steel（（55 ± 1） HRC） by coated and uncoated carbide insert in adry environment. Micro hardness and abrasion tests werecarried out to assess resistance capability against wear. Theabove test results confirmed the greater wear resistanceability of AIaO3 coated carbide insert over uncoated car-bide. Based on the extensive investigation of comparativemachinability, the coated carbide insert （TiN-TiCN-A12O3）outperformed the uncoated carbide insert with regard tosurface roughness, flank wear, chip-tool interface temper-ature, and chip morphology. Abrasion and diffusion wereobserved as the principal tool wear mechanisms in theinvestigated range. The uncoated carbide failed completelydue to the severe chipping and quick dulling of the cuttingedge, which led to its unsuitability for machining hardenedsteel.

关键词： Coated and uncoated carbide Hard turning Machinability Flank wear Surface roughness Chipmorphology Cutting temperature

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