检索结果-南通市图书馆

Association Between IL-6 （Interleukin-6） and Iron Status in Rheumatoid Arthritis Patients

Journal of Life Sciences 2014年第5期8卷 404-409页

作者： Abbas Sabbar Dkhil musa Nima Mezher Physiology Department Faculty of Medicine University of Qadisiyah Qadisiyah 58002 Iraq Biology Department Faculty of Science University of Kufa Najaf Qadisiyah 58002 Iraq

The study was performed to determine whether the srum concentrations of IL （interleukin）-6 are elevated in patients with ra （rheumatoid arthritis） and to investigate the relationship between IL-6 levels and iron status in ra patients. 95 serum samples were obtained, 70 of them from patients with ra who had visited the department of Rheumatology at Al-Sadder medical city in Najaf governorate （Iraq） and 25 age and sex-matched healthy controls. The authors assessed the clinical parameters of the disease, including ESR （erythrocyte sedimentation rate）, CRP （C-reactive protein）, and RF （rheumatoid factor）. Serum levels of iron and TIBC （total iron binding capacity） were measured spectrophotometrically, while TS% （transferrin saturation percentage） and transferrin concentration were calculated mathematically. Serum concentrations of IL-6 （interleukin-6） and ferritin were measured using an ELISA （enzyme-linked immunosorbent assay）. The results of serum concentration of IL-6 （interleukin-6） and ferritin were significantly elevated （P 〈 0.0001） in patients with ra compared to those of healthy controls. On the other hand, serum concentrations of iron, TIBC （total iron binding capacity）, TS% （transferrin saturation percentage） and transferrin concentration were significantly decreased in patients with ra compared with those of healthy controls. These findings suggest that anemia is the most frequent observations in patients with ra and mostly associative with increasing level of interleukin-6.

关键词： Rheumatoid arthritis interleukin-6 Iron status ACD (anemia of chronic diseases) proinflammatory cytokines.

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Cardiovascular Risk Burden in Sub-Saharan Africans with Rheumatoid Arthritis: A Hospital-Based Study in Yaounde, Cameroon

引用

Open Journal of Rheumatology and Autoimmune Diseases 2016年第1期6卷 1-9页

作者： Madeleine Singwe-Ngandeu Mickael Essouma Vicky Jocelyne Ama Moor Ahmadou Jingi musa Alain Patrick Menanga Caroline Ngoufack Sandrine Sa’a Lontsi Thierry Ntandzi Yolande Vanessa Ayi Efoua Mireille Cathy Melong Pianta Faculty of Medicine and Biomedical Sciences The University of Yaoundé I Yaounde Cameroon Rheumatology Unit Yaounde Central Hospital Yaounde Cameroon Biochemistry Laboratory Yaounde University Teaching Hospital Yaounde Cameroun Cardiology Unit Yaounde General Hospital Yaounde Cameroon

Introduction: Studies on ra (rheumatoid arthritis) and cardiovascular risk in African countries are scarce. Objective: To investigate the relationship between ra and cardiovascular risk in Cameroonian patients. Methodology: In 50 Black ra patients and 51 matched healthy individuals from the general population, we studied cardiovascular risk factors validated by the WHO. Cardiovascular risks estimates were carried out using WHO risk charts for the African region. Epi-info, R and SPPS were used for the statistical analysis. Results: Overall and abdominal adiposity as expressed by increased body mass index and abdominal obesity, were all markedly increased in ra patients compared to non-ra subjects [70% vs. 47%, OR (95% CI) = 2.62 (1.16 - 5.94), p = 0.026;and 54% vs. 33%, OR (95% CI) = 2.34 (1.05 - 5.25), p = 0.045 respectively]. ra patients were more physically inactive than their non-ra counterparts (20% vs. 0, p = 0.001). Whereas ra was associated with a reduced odds of alcoholism [OR (95% CI) = 0.19 (0.06 - 0.62), p = 0.005]. Increased BMI seemed to occur independently of methotrexate (p = 0.76), hydroxychloroquine (p = 0.59), corticosteroids (p = 0.79) treatments, and independently of sex (p = 0.15), age (p = 0.67), and sedentary lifestyle (p = 0.16) in ra patients;but their BMI was weakly correlated with disease duration (r = 0.26;p = 0.074). Meanwhile, male gender was associated with a reduced odds of abdominal obesity [OR (95% CI) = 0.02 (0 - 0.4), p = 0.011]. Cardiovascular risk, comparable by proportions between ra and non-ra subjects, was low in 26 patients (78.8%) and 30 non-ra subjects (83.3%) respectively. Conclusion: Despite the high adiposity burden and a sedentary lifestyle experienced by ra patients compared to their healthy counterparts, ra was not associated with cardiovascular risk as estimated by WHO risk charts.

关键词： Rheumatoid Arthritis Excess Adiposity Physical Inactivity Cardiovascular Risk World Health Organization Risk Charts

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

吐尔洪·艾买尔教授维医诊疗类风湿性关节炎的学术思想

引用

中国民族医药杂志 2021年第11期27卷 34-37页

作者：伊力夏提·买买提热扑开提·赛吾力丁帕尔哈提·热甫开提米尔佧米力·麦麦提依明海热拉·木萨克热木江·买买祖努库娜迪拉·艾伯都拉新疆维吾尔自治区维医医院新疆乌鲁木齐830049

类风湿性关节炎是一种慢性以炎性滑膜炎为主的系统性疾病,病因病机尚未明确。维医对类风湿性关节炎有独具特色的认识和治疗方法,吐尔洪·艾买尔教授从事中医(维医学)临床治疗、研究及教学工作50余年,对类风湿性关节炎的防治及治疗有独... 详细信息

类风湿性关节炎是一种慢性以炎性滑膜炎为主的系统性疾病,病因病机尚未明确。维医对类风湿性关节炎有独具特色的认识和治疗方法,吐尔洪·艾买尔教授从事中医(维医学)临床治疗、研究及教学工作50余年,对类风湿性关节炎的防治及治疗有独特的学术思想。在临床治疗中重视病因病机,维医药内外兼治,辨证分析,准确辨认疾病发展的环境因素,灵活运用中草药的组方,熟练应用维医外用治疗技术。本文对吐尔洪·艾买尔教授治疗类风湿性关节炎的学术思想和诊疗经验进行总结。

关键词：类风湿性关节炎维医疗法辨别体液质学术思想

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：