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Input database related uncertainty of Biome-BGCMuso agroenvironmental model outputs

International Journal of Digital Earth 2021年第11期14卷 1582-1601页

作者： Nándor Fodor lászlóPásztor Brigitta szabó Annamária laborczi Klára Pokovai Dóra Hidy Roland Hollós Erzsébet Kristóf Anna Kis laura Dobor AnikóKern Thomas Grünwald Zoltán Barcza Centre for Agricultural Research Agricultural InstituteMartonvásárHungary Centre for Agricultural Research Institute for Soil SciencesBudapestHungary Department of Meteorology Eötvös Loránd UniversityBudapestHungary Faculty of science-Excellence Center Eötvös Loránd UniversityMartonvásárHungary Faculty of Forestry and Wood sciences Czech University of Life Sciences PraguePraha-SuchdolCzech Republic Department of Geophysics and space science Eötvös Loránd UniversityBudapestHungary Institute of Hydrology and Meteorology Technische Universität DresdenTharandtGermany

Gridded model assessments require at least one climatic and one soil database for carrying out the *** are several parallel soil and climate database development projects that provide sufficient,albeit considerably different,observation based input data for crop model based impact *** input database related uncertainty of the Biome-BGCMuso agro-environmental model outputs was investigated using three and four different gridded climatic and soil databases,respectively covering an area of nearly 100.000 km2 with 1104 grid ***,temporal,climate and soil database selection related variances were calculated and compared for four model outputs obtained from 30-year-long *** choice of the input database introduced model output variability that was comparable to the variability the year-to-year change of the weather or the spatial heterogeneity of the soil *** database selection could be a decisive factor in carbon sequestration related studies as the soil carbon stock change estimates may either suggest that the simulated ecosystem is a carbon sink or to the contrary a carbon source on the long *** evaluation of the input database quality seems to be an inevitable and highly relevant step towards more realistic plant production and carbon balance simulations.

关键词： Input data gridded data soil parameters climatic parameters uncertainty propagation

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Quality indicators in subtropical soils of Formosa,Argentina:Changes for agriculturization process

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International soil and Water Conservation Research 2014年第4期2卷 13-24页

作者： Juan Esteban Baridón Roberto raúl Casas Universidad Nacional de la Plata Buenos AiresArgentina laboratorio de suelos Aguas y Forrajes.Centro de Validación de Tecnologías Agropecuarias IbarretaIbarreta(CP 3624)FormosaArgentina Centro de Investigación de Recursos Naturales.Instituto Nacional de Tecnología Agropecuaria:Dr.Nicolás Repetto(ex las Cabañas)y los Reseros Castelar(CP1712)Buenos AiresArgentina

The agriculturization process has been defined as the advance of annual crops in different environments,in competition with traditional land uses such as agriculture rotations with *** Argentina and other countries agriculturization has different degrees of impact on natural *** the northeast region of the province of Formosa,Argentina,agriculturization includes deforestation(clear cutting,slash burning and plowing),technological improvements and changes in land *** of these alterations,it is necessary to define the state of the soil to evaluate its *** can be done by means of indicators,which are not universal;they differ according to the use,management and type of soils,weather conditions and *** objectives of this paper are:(1)To identify quality indicators for subtropical Argiudolls and Hapludolls;(2)To determine which indicators related to organic matter are most affected during *** changes produced in the Typic Hapludolls and Typic Argiudolls after 25 years of continuously using native forests,agriculture,fruit plantations and pastures were *** changes were in pH,electrical conductivity,total organic carbon,particulate organic carbon,total nitrogen,structural stability,hydraulic conductivity,respiration and dehydrogenase and urease and enzyme *** with significant differences between diverse uses were evaluated by multivariate methods,Principal Component Analysis,and Correlation *** results of this study showed that total organic carbon,particulate organic carbon,structural stability and dehydrogenase activity are the quality indicators most affected by *** are related to organic matter.

关键词： Hapludolls Argiudolls soil quality soil use

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Mid-term outcomes of a kinematically designed cruciate retaining total knee arthroplasty

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World Journal of Orthopedics 2024年第2期15卷 118-128页

作者： Jonathan l Katzman Akram A Habibi Muhammad A Haider Casey Cardillo Ivan Fernandez-Madrid Morteza Meftah ran schwarzkopf Department of Orthopedic surgery Division of Adult Reconstructive SurgeryNYU Langone Orthopedic HospitalNYU Langone HealthNew YorkNY 10010United States

BACKGROUND Advances in implant material and design have allowed for improvements in total knee arthroplasty(TKA)outcomes.A cruciate retaining(CR)TKA provides the least constraint of TKA designs by preserving the native posterior cruciate *** research exists that has examined clinical outcomes or patient reported outcome measures(PROMs)of a large cohort of patients undergoing a CR TKA utilizing a kinematically designed *** was hypothesized that the studied CR Knee system would demonstrate favorable outcomes and a clinically significant improvement in pain and functional *** To assess both short-term and mid-term clinical outcomes and PROMs of a novel CR TKA *** A retrospective,multi-surgeon study identified 255 knees undergoing a TKA utilizing a kinematically designed CR Knee system(JOURNEY™II CR;smith and Nephew,Inc.,Memphis,TN)at an urban,academic medical institution between March 2015 and July 2021 with a minimum of two-years of clinical follow-up with an orthopedic *** demographics,surgical information,clinical outcomes,and PROMs data were collected via query of electronic medical *** PROMs collected in the present study included the Knee Injury and Osteoarthritis Outcome score for Joint Replacement(KOOs JR)and Patient-Reported Outcomes Measurement Information system(PROMIs■)*** significance of improvements in mean PROM scores from preoperative scores to scores collected at six months and two-years postoperatively was analyzed using Independent samples *** Of the 255 patients,65.5%were female,43.8%were White,and patients had an average age of 60.6 *** osteoarthritis(96.9%)was the most common primary *** mean surgical time was 105.3 minutes and mean length of stay was 2.1 d with most patients discharged home(92.5%).There were 18 emergency department(ED)visits within 90 d of surgery resulting in a 90 d ED visit rate of 7.1%,including a 2.4%orthopedic-related ED visit ra

关键词： Total knee arthroplasty Cruciate retaining Kinematic design survivorship Bearing material Prosthetic design Clinical outcomes Patient-reported outcome measures

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Influence of flooding and vegetation on carbon,nitrogen,and phosphorus dynamics in the pore water of a spartina alterniflora salt marsh

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Journal of Environmental sciences 2011年第2期23卷 212-221页

作者： Vanesa l.Negrin Carla V.spetter raúl O.Asteasuain Gerardo M.E.Perillo Jorge E.Marcovecchio Argentine Institute of Oceanography (IADO CONICETCCT-Bahía Blanca)Camino La Carrindanga km 75Building E-1 CC 804Bahía Blanca 8000Argentina Department of Chemistry Southern National Institute of Chemistry (INQUISUR)Southern National University (UNS)Av Alem 1253Bahía Blanca 8000Argentina Department of Geology Southern National University (UNS)San Juan 670Bahía Blanca 8000Argentina National Technological University Regional Faculty of Bahía Blanca (UTN-FRBB)11 de Abril 461Bahía Blanca 8000Argentina University of the Fraternity of Associations santo Toms de Aquino (FAsTA) Gascón 3145Mar del Plata 7600Argentina

Four sites were selected in a salt marsh in the Bahia Blanca Estuary （Argentina）：（1） low marsh （flooded by the tide twice daily） vegetated by s. alterniflora; （2） non-vegetated low marsh; （3） high marsh （flooded only in spring tides） vegetated by s. alterniflora; （4） non-vegetated high marsh. The pH and Eh were measured in sediments, while dissolved nutrients （ammonium, nitrate, nitrite and phosphate） and particulate organic matter （POM） were determined in pore water, pH （6.2-8.7） was only affected by vegetation in low areas. Eh （from -300 to 250 mV） was lower at low sites than at high ones; in the latter, the values were higher in the non-vegetated sediments. The POM concentration was greater in the high marsh than in the low marsh, with no effect of vegetation. Ammonium was the most abundant nitrogen nutrient species in pore water, except in the non-vegetated high marsh where nitrate concentration was higher. All nitrogen nutrients were affected by both flooding and vegetation. Phosphate was always present in pore water at all sites throughout the year and its concentration varied within narrow limits, with no effect of flooding and greater values always at non-vegetated sites. Our results showed that the variability of the pore water composition within the marsh is greater than the temporal variation, meaning that both tidal flooding and vegetation are important in the dynamics of nutrients and organic matter in the sediment pore water.

关键词： organic matter nutrients flooding spartina alterniflora

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Arylamine N-acetyltransferase 2 genotype-dependent N-acetylation of isoniazid in cryopreserved human hepatocytes

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Acta Pharmaceutica sinica B 2017年第4期7卷 517-522页

作者： Mark A.Doll raúl A.salazar-González srineil Bodduluri David W.Hein Department of Pharmacology and Toxicology and James Graham Brown Cancer Center University of LouisvilleLouisvilleKY 40202USA

Cryopreserved human hepatocytes were used to investigate the role of arylamine N-acetyltransferase 2 (NAT2; EC 2.***.1.5) polymorphism on the N-acetylation of isoniazid (INH). NAT2 genotype was determined by Taqman allelic discrimination assay and INH N-acetylation was measured by high performance liquid chromatography. INH N-acetylation rates in vitro exhibited a robust and highly significant (Plism. N-acetylation rates in situ were INH concentration- and time-dependent. Following incubation for 24 h with 12.5 or 100 µmol/l INH, acetyl-INH concentrations varied significantly (P = 0.0023 and P = 0.0002) across cryopreserved human hepatocytes samples from rapid, intermediate, and slow acetylators, respectively. The clear association between NAT2 genotype and phenotype supports use of NAT2 genotype to guide INH dosing strategies in the treatment and prevention of tuberculosis.

关键词： Isoniazid N-Acetyltransferase 2 Acetylation polymorphism Human hepatocytes Genotype Phenotype

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Effect of silver-nanoparticles generated in poly(vinyl alcohol)membranes on ethanol dehydration via pervaporation

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Chinese Journal of Chemical Engineering 2019年第7期27卷 1595-1607页

作者： Asmaa selim Andras Jozsef Toth Daniel Fozer Eniko Haaz Nóra Valentínyi Tibor Nagy Orsolya Keri lászlo Péter Bakos Imre Miklós szilágyi Peter Mizsey Department of Chemical and Environmental Process Engineering Budapest University of Technology and Economics1111 BudapestHungary Chemical Engineering Department National Research Centre12611 GizaEgypt Department of Inorganic and Analytical Chemistry Budapest University of Technology and Economics1111 BudapestHungary Department of Fine Chemicals and Environmental Technology University of Miskolc3515 MiskolcHungary

Pervaporation is an important membrane separation method of chemical *** this work,silver-nanoparticles-poly(vinyl alcohol)nanocomposite membranes(AgNPs-PVA)are produced for the sake of improving its potentials for pervaporation of ethanol–water mixture so that the usual opposite trend between membrane selectivity and permeation can be *** nanocomposite membranes are fabricated from an aqueous solution of poly(vinyl alcohol)with silver nanoparticles via the in-situ generation technique in the absence of any reducing *** generation of the nano size silver is measured by the UV–vis spectrum showing a single peak at 419 nm due to the plasmonic effect of silver *** nanocomposite AgNPs-PVA membranes are characterized using scanning electron microscope(sEM),Fourier-transform infrared(FT-IR)spectroscopy,X-ray diffraction and thermogravimetric analysis(TGA).The pervaporation tests of our new AgNPs-PVA membranes show good results since at a higher temperature and higher ethanol concentration in the feed,the prepared membranes are highly permeable for the water having stable selectivity values and therefore our membranes show better performance compared to that of the other PVA-based nanocomposite membranes.

关键词： silver nanoparticle Poly(vinyl alcohol)nanocomposite membrane Hydrophilicity swelling degree Pervaporation

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Glutamine metabolism in cancer therapy

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Cancer Drug Resistance 2018年第3期1卷 126-138页

作者： Tra-ly Nguyen raúl V.Durán Institut Européen de Chimie et Biologie INSERM U1218Universitéde Bordeaux2 Rue Robert Escarpit33607 PessacFrance.

The amino acid glutamine plays a key role in the metabolism of highly proliferating *** malignant transformation,cancer cells modify the consumption and processing of glutamine to sustain cell growth and *** some cases,these cancer cells become addicted to ***,targeting the metabolism of glutamine has been developed during last years as a potential strategy against *** this review,we summarized the last advances in our knowledge about the role of glutamine metabolism in cancer therapy.

关键词： Cancer glutamine glutamoptosis metabolism mammalian target of rapamycin

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Effects of phosphorus fertilizer application on phosphorus fractions in different organs of Cordia trichotoma

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Journal of Forestry Research 2021年第2期32卷 725-732页

作者： Matheus s.s.Kulmann lincon O.s.stefanello raíA.schwalbert Álvaro l.P.Berghetti Maristela M.Araujo Rogerio Piccin luciano C.Gatiboni Tales Tiecher Paulo A.A.Ferreira Gustavo Brunetto Department of soil science Federal University of Santa MariaSanta MariaRio Grande do SulBrazil Department of Rural Engineering Federal University of Santa MariaSanta MariaRio Grande do SulBrazil Department of Forest Engineering Federal University of Santa MariaSanta MariaRio Grande do Sul 97105-900Brazil Agroveterinary science Center State University of Santa CatarinaLagesSanta Catarina88520-000Brazil Department of soil science Federal University of Rio Grande do SulPorto AlegreRio Grande do Sul 91540-000Brazil

The application of phosphorus(P)to soil can increase its availability to plants and alter P fractions in annual and perennial organs of Cordia *** a portion of P accumulates in perennial organs in organic fractions it can be used in the next growth season,possibly decreasing plant dependence on P derived from soil ***,if P is preferentially accumulated in inorganic fractions in annual organs,plants will be more dependent on phosphate *** study aimed to evaluate the distribution of P fractions in organs of *** grown on sandy soil treated with 120 and 360 kg P2O5 ha^(−1).The control was a zero *** 24 months following fertilization,*** seedlings were cut and separated into leaves,branches,stems and roots,dried,ground and subjected to chemical fractionation of P,which estimates fractions of total soluble P,soluble inorganic and organic P,lipid P,P associated ribonucleic acid and deoxyribonucleic acid,and residual P.P in annual organs,as leaves,accumulated preferentially in the soluble inorganic fraction in both *** perennial organs such as stems and branches,P accumulated preferentially in the soluble organic *** application of 300%of the recommended dosage(360 kg P2O5 ha^(−1))promoted the accumulation of P in soluble organic fractions which may contribute to annual growth the following season and be a strategy to reduce the dependence of 2-year-old stands on soil-derived P and on fertilizers.

关键词： Chemical fractionation Phosphorus Phosphate fertilization Plant phosphorus

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liver dysfunction and sARs-CoV-2 infection

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World Journal of Gastroenterology 2021年第26期27卷 3951-3970页

作者： Abraham Edgar Gracia-ramos Joel Omar Jaquez-Quintana raúl Contreras-Omaña Moises Auron Department of Internal Medicine General HospitalNational Medical Center"La Raza"Instituto Mexicano del Seguro SocialMexico City 02990Mexico Gastroenterology service and Department of Internal Medicine Faculty of MedicineUniversity Hospital"Dr.JoséE.González"Universidad Autónoma de Nuevo LeónMonterrey 64460Mexico Centro de Estudio e Investigación en Enfermedades Hepáticas y Toxicológicas(CEIHET) Pachuca 42184Mexico Departments of Hospital Medicine and Pediatric Hospital Medicine Cleveland ClinicClevelandOH 44195United States

severe acute respiratory syndrome coronavirus 2 infection is the cause of coronavirus disease 2019(COVID-19),which predominantly affects the respiratory system;it also causes systemic and multi-organic *** damage is among the main extrapulmonary ***-19-associated liver injury is defined as any liver damage occurring during the disease course and treatment of COVID-19 in patients with or without pre-existing liver disease,and occurs in approximately one in five *** liver test results have been associated with a more severe course of COVID-19 and other complications,including *** linking COVID-19 to liver injury are *** consideration should be made for patients with pre-existing liver disease,such as metabolic dysfunction-associated fatty liver disease,chronic liver disease due to viral or autoimmune disease,liver transplant carriers,or cirrhosis,given the risk for more severe *** manuscript summarizes the current lines of evidence on COVID-19-associated liver injury regarding pathophysiology,clinical significance,and management in both patients with or without preexisting liver disease,to facilitate clinicians’access to updated information and patient ***,we mention the ideas and recommendations to be considered for future research.

关键词： sARs-CoV-2 Coronavirus COVID-19 liver liver diseases liver failure liver injury Cirrhosis

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severity of gastroesophageal reflux disease influences daytime somnolence: A clinical study of 134 patients underwent upper panendoscopy

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World Journal of Gastroenterology 2004年第12期10卷 1798-1801页

作者： Pái Demeter Katalin Várdi Visy Nóra Gyulai Róbert sike Tamás G Tóth János Novák Pál Magyar Outpatient Clinic of Gastroenterology St.John's HospitalBudapestHungary Department of Pulmonology Semmelweis Medical UniversityBudapestHungary Dept.of

AIM: To asses the relationship between severity of gastroesophageal refluxe disease and Epworth sleepiness scale as an indicator of daytime somnolence. METHODs: One hundred and thirty-four patients underwent an upper panendoscopy as indicated by the typical reflux symptoms and were also investigated with regard to somnolence. sleepiness was evaluated by Epworth sleepiness scale, which was compared to the severity of endoscopic findings (savary-Miller/modified by siewert). Patients with psychiatric disorders or being on sedato-hypnotics as well as shift workers were excluded from the study. The relationship between the severity of the reflux disease and daytime somnolence was analyzed with the help of multivariate regression analysis. REsUlTs: A positive tendency was found between the severity of the reflux disease and the corresponding Epworth sleepiness scale. In the case of the more severe type-savary-Miller Ⅲ- at least a mild hypersomnia was found. For this group daytime somnolence was significantly higher than in the case of the non-erosive type of Gastroesophageal Reflux Disease representing the mildest stage of reflux disease. CONClUsION: The severity of Gastroesophageal Reflux Disease influences daytime somnolence.

关键词： severity of Illness Index Adult Aged Disorders of Excessive somnolence Endoscopy, Digestive system Female Gastroesophageal Reflux Humans linear Models Male Middle Aged Predictive Value of Tests

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