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Oncology Research 2024年第8期32卷 1323-1334页

作者： ruifang li XINRONG NAN MING li OMAR RAHHAL School of Stomatology Shanxi Medical UniversityTaiyuan030001China Department of Stomatology The First Hospital of Shanxi Medical UniversityTaiyuan030001China Department of Oral and Maxillofacial Surgery Xiangya Stomatology HospitalCentral South UniversityChangsha410005China

Background:Fibroblast activation protein(FAP),a cell surface serine protease,plays roles in tumor invasion and immune ***,there is currently no pan-cancer analysis of ***:We aimed to assess the pan-cancer expression proﬁle of FAP,its molecular function,and its potential role in head and neck squamous cell carcinoma(HNSC).Methods:We analyzed gene expression,survival status,immune inﬁltration,and molecular functional pathways of FAP in The Cancer Genome Atlas(TCGA)and Genotype Tissue Expression(GTEx)***,to elucidate the role of FAP in HNSC,we performed proliferation,migration,and invasion assays post-FAP overexpression or ***:FAP expression was elevated in nine tumor types and was associated with poor survival in eight of *** the context of immune inﬁltration,FAP expression negatively correlated with CD8+T-cell inﬁltration inﬁve tumor types and positively with regulatory T-cell inﬁltration in four tumor *** enrichment analysis highlighted FAP’s involvement in the PI3K-Akt signaling *** HNSC cells,FAP overexpression activated the PI3K-Akt pathway,promoting tumor proliferation,migration,and ***,FAP knockdown showed inhibitory ***:Our study unveils the association of FAP with poor tumor prognosis across multiple cancers and highlights its potential as a therapeutic target in HNSC.

关键词： FAP Head and neck squamous cell carcinoma Cancer Prognosis Tumor microenvironment Molecular function

Fuzzy ta/2 symmetries of straight chain conjugate polyene molecules

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Science China Chemistry 2009年第11期52卷 1892-1910页

作者： li Yun ZHAO XueZhuang XU XiuFang SHANG ZhenFeng ZHOU Zhen CAI ZunSheng WANG GuiChang li ruifang College of Chemistry Nankai UniversityTianjin 300071China

On the basis of our recent studies on the molecular fuzzy point group symmetry,we further probe into the more complicated planar one-dimensional fuzzy periodic molecules-straight chain conjugate *** for the fuzzy translation transformation,the space transformation of the fuzzy screw rotation and the glide plane will be referred *** addition,other fuzzy point symmetry transformation lain in the space transformation is *** there is a correlation between the fuzzy symmetry characterization caused by the transition of the point symmetry elements and by certain space symmetry *** the molecular orbital,the irreducible representation component is analyzed besides the membership function of the fuzzy symmetry ***,we inquire into the relativity between some molecular property and the fuzzy symmetry characterization.

关键词： conjugate polyene one-dimensional fuzzy periodic transformation the membership function irreducible representation component

Jointly Build the Belt and Road Initiative with a Two-Wheel Drive——International Work of The Amity Foundation

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International Understanding 2019年第3期 68-72页

作者： li ruifang 不详

With the development of economy and society,China’s comprehensive national strength has been continuously enhanced and its international influence has been *** is shouldering more international responsibilities and obligations to make greater contributions to building a community of shared future for mankind by“always being a builder of world peace,a contributor to global development,and a defender of the international order”.In March 2015,President Xi Jinping put forward the concept of the Belt and Road Initiative,which not only pointed out the way for Chinese social organizations to participate in international affairs,but also opened up unprecedented opportunities for Chinese social organizations to further participate in global governance.

关键词： Jointly Build the Belt and Road Initiative Two-Wheel Drive International Work The Amity Foundation

2019 World Canal Conference Held in Yangzhou,China

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International Understanding 2019年第3期 65-67页

作者： li ruifang 不详

On Sept.27 th,2019 World Canal Conference was held in Yangzhou,jointly organized by People’s Government of Yangzhou City, the World Canal Historical and Cultural City Cooperation Organization (WCCO), and the Inland W... 详细信息

关键词： World Canal Conference Held Yangzhou,China

Chinese Social Organizations Participate in the UN Katowice Climate Change Conference

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International Understanding 2018年第4期 59-60页

作者： Wang Zhiyun li ruifang 不详

From December 2nd to 14th,2018,the 24th Session of the UN Climate Change Conference was held in Katowice,known as"the capital of coal",*** conference included the 24th Meeting of the Parties to the UN Framework Convention on Climate Change (COP24),the 14th Meeting of the Parties to the Kyoto Protocol (CMP14) and PartⅢof the First Meeting of the Conference of the Parties to Paris Agreement (CMA1-3),*** from more than 190 countries commenced negotiations on the implementing regulations of Paris Agreement.

关键词： Chinese Social Organizations Climate Change

China Youth Delegation Visits Israel

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International Understanding 2018年第4期 45-46页

作者： Wang Zhiyun li ruifang 不详

At the invitation of the Israel Youth Exchange Council,a six-member Chinese youth delegation including the author,led by Jia Tiesong,Assistant Director of China Youth Center for International Exchanges,paid a visit to Israel from November11th to 15th,*** got a deeper understanding of Israel’s national conditions,history,innovation industry and youth,the delegation exchanged views with the Israeli side on institutionalized exchanges and other issues.

关键词： China Youth Delegation Israel

The phytopathogen Xanthomonas campestris senses and effluxes salicylic acid via a sensor HepR and an RND family efflux pump to promote virulence in host plants

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mlife 2024年第3期3卷 430-444页

作者： Kai Song ruifang li Ying Cui Bo Chen lian Zhou Wenying Han Bo-Le Jiang Ya-Wen He State Key Laboratory of Microbial Metabolism Joint International Research Laboratory of Metabolic and Developmental SciencesSchool of Life Sciences and BiotechnologyShanghai Jiao Tong UniversityShanghaiChina Guangxi Key Laboratory of Biology for Crop Diseases and Insect Pests Plant Protection Research InstituteGuangxi Academy of Agricultural SciencesNanningChina Zhiyuan Innovative Research Center Shanghai Jiao Tong UniversityShanghaiChina State Key Laboratory for Conservation and Utilization of Subtropical Agro-bioresources College of Life Science and TechnologyGuangxi UniversityNanningChina

Salicylic acid(SA)plays an essential role in plant defense against biotrophic and semi-biotrophic *** pathogen recognition,SA biosynthesis dramatically increases at the infection site of the host *** manner in which pathogens sense and tolerate the onslaught of SA stress to survive in the plant following infection remains to be *** objective of this work was to determine how the model phytopathogen Xanthomonas campestris ***(Xcc)senses and effluxes SA during infection inside host ***,RNA-Seq analysis identified an SA-responsive operon Xcc4167-Xcc4171,encoding a MarR family transcription factor HepR and an RND(resistance-nodulation-cell division)family efflux pump HepABCD in *** mobility shift assays and DNase I footprint analysis revealed that HepR neg-atively regulated hepABCD expression by specifically binding to an AT-rich region of the promoter of the hepRABCD operon,***,isothermal titration calorimetry and further genetic analysis suggest that HepR is a novel SA *** binding released HepR from its cognate promoter Pnep and then induced the expression of ***,the RND family efflux pump HepABCD was responsible for SA *** hepRABCD cluster was also involved in the regulation of culture pH and quorum sensing signal diffusible signaling factor ***,the hepRABCD cluster was transcribed during the XC1 infection of Chinese radish and was required for the full virulence of Xcc in Chinese radish and *** findings suggest that the ability of Xcc to co-opt the plant defense signal SA to activate the multidrug efflux pump may have evolved to ensure Xcc survival and virulence in susceptible host plants.

关键词： efflux quorum sensing salicylic acid sensor Xanthomonas campestris

East Meets West, Acupuncture Benefits the World “The Beauty of China”——TCM Acupuncture-Moxibustion into UNESCO Headquarters

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International Understanding 2018年第4期 61-62页

作者： Yang Yuyang liu Jingyuan li ruifang World Federation of Acupuncture-Moxibustion Societies

On November 15th,2018,"Special Events of World Acupuncture-Moxibustion Day into UNESCO"were held at the UNESCO headquarters in Paris,France,to celebrate the 8th anniversary of traditional Chinese medicine (TCM) acupun... 详细信息

关键词： Acupuncture China UNESCO

Defect Detection of Bamboo Strips Based on LBP and GLCM Features by Using SVM Classifier

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Defect Detection of Bamboo Strips Based on LBP and GLCM Feat...

第30届中国控制与决策会议

作者： Hailan Kuang Yiran Ding ruifang li Xinhua liu School of Information Engineering Wuhan University of Technology Key Laboratory of Fiber Optic Sensing Technology and Information Processing Wuhan University of Technology Ministry of Education

With the improvement of bamboo mat production, the higher requirements have been proposed for the using of bamboo strips which makes the defect detection of bamboo strips vital for mat quality. Various defects emerge in the bamboo strips will greatly affect product quality and reduce the productive efficiency. In fact, the defect detection of bamboo strips by manpower can not be guaranteed in terms of efficiency and quality, then forcing companies to work with automatic systems in this area. In this paper, we propose a method for defect detection of bamboo strips using a set of features based on LBP（Local Binary Pattern） and GLCM（Gray-level Co-occurrence Matrix）. In the image preprocessing, we use the threshold algorithms to extract the region of interest（ROI）, and then the two algorithms are combined to detect the texture of the ROI region and finally the SVM classifier is used to classify the bamboo strips. Experimental results show that the algorithms have a good performance on defect detection. The accuracy of the classification is 97.76%, which can greatly improve the productive efficiency.

关键词： LBP GLCM Defect Detection SVM

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创意农业视角下的农业科技发展对策

科技管理研究 2010年第22期30卷 46-48页

作者：李瑞芳中共濮阳市委党校河南濮阳457000

以创意农业带动社会主义新农村建设,是实现社会主义新农村建设目标的一条创新之路。农业科技是创意农业的主要组成部分,是助推创意农业发展的动力源泉,农业科技的发展水平和推广应用状况是发展创意农业的重要前提和制约因素。创意农业... 详细信息

以创意农业带动社会主义新农村建设,是实现社会主义新农村建设目标的一条创新之路。农业科技是创意农业的主要组成部分,是助推创意农业发展的动力源泉,农业科技的发展水平和推广应用状况是发展创意农业的重要前提和制约因素。创意农业对农业科技有着特殊要求。在发展创意农业的过程中,必须采取得力措施,充分发挥农业科技的技术支撑和智力保障作用。

关键词：创意农业农业科技特殊要求促进对策