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Novel Design Solutions for Fishing Reel Mechanisms

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Chinese Journal of Mechanical Engineering 2015年第4期28卷 726-736页

作者： LOVASZ Erwin-Christian MODLER Karl-Heinz NEUMANN rudolf GRUESCU Corina Mihaela PERJU Dan CIUPE Valentin MANIU Inocentiu Department of Mechatronics University Politehnica Timisoara Institut für Festkrpermechanik Technische Universitt Dresden

Currently, there are various reels on the market regarding the type of mechanism, which achieves the winding and unwinding of the line. The designers have the purpose of obtaining a linear transmission function, by means of a simple and small-sized mechanism. However, the present solutions are not satisfactory because of large deviations from linearity of the transmission function and complexity of mechanical schema. A novel solution for the reel spool mechanism is proposed. Its kinematic schema and synthesis method are described. The kinematic schema of the chosen mechanism is based on a noncircular gear in series with a scotch-yoke mechanism. The yoke is driven by a stud fixed on the driving noncircular gear. The drawbacks of other models regarding the effects occurring at the ends of the spool are eliminated through achieving an appropriate transmission function of the spool. The linear function approximation with curved end-arches appropriately computed to ensure mathematical continuity is very good. The experimental results on the mechanism model validate the theoretical approach. The developed mechanism solution is recorded under a reel spool mechanism patent.

关键词： reel mechanism noncircular gears analysis synthesis transmission function

利用强子探针研究奇特原子核的点质子分布半径及强子探针效应

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Science Bulletin 2024年第11期69卷 1647-1652页

作者：张寂潮孙保华 Isao Tanihata Rituparna Kanungo Christoph Scheidenberger Satoru Terashima 王枫 Frederic Ameil Joel Atkinson Yassid Ayyad Soumya Bagchi Dolores Cortina-Gil Iris Dillmann Alfredo Estradé Alexey Evdokimov Fabio Farinon Hans Geissel Giulia Guastalla rudolf Janik Satbir Kaur Ronja Knöbel Jan Kurcewicz Yury Litvinov Michele Marta Magdalena Mostazo Ivan Mukha Chiara Nociforo Hooi Jin Ong Stephane Pietri Andrej Prochazka Branislav Sitar Peter Strmen Maya Takechi Junki Tanaka Jossitt Vargas Helmut Weick John Stuart Winfield School of Physics Beihang UniversityBeijing 100191China Research Center for Nuclear Physics(RCNP) Osaka UniversityOsaka 567-0047Japan Astronomy and Physics Department Saint Mary’s UniversityHalifax B3H 3C3Canada TRIUMF Vancouver V6T 4A3Canada GSI Helmholtzzentrum für Schwerionenforschung Darmstadt D-64291Germany Justus-Liebig University Gießn 35392Germany Helmholtz Research Academy Hesse for FAIR(HFHF) GSI Helmholtz Center for Heavy Ion ResearchGießn 35392Germany Universidad de Santiago de Compostela Santiago de Compostella E-15706Spain Department of Physics Indian Institute of Technology(Indian School of Mines)Dhanbad 826004India Faculty of Mathematics and Physics Comenius UniversityBratislava 84215Slovakia Department of Physics and Atmospheric Science Dalhousie UniversityHalifax B3H 4R2Canada

We report the charge-changing cross sections(σ_(cc))of 24 p-shell nuclides on both hydrogen and carbon at about 900A MeV,of which^(8,9)Li,^(10–12)Be,^(10,14,15)B,^(14,15,17–22)N and^(16)O on hydrogen and^(8,9)Li on carbon are for the first *** from the data set,we found a new and robust relationship between the scaling factor of the Glauber model calculations and the separation energies of the nuclei of interest on both *** allows us to deduce proton radii(R_p)for the first time from the cross sections on *** identical R_p values are deduced from both target data for the neutron-rich carbon isotopes;however,the R_p from the hydrogen target is systematically smaller in the neutron-rich nitrogen *** calls for further experimental and theoretical investigations.

关键词： Exotic nuclei Nuclear size Reaction cross section Glauber model Radioactive ion beam

Long-term survival after pancreaticoduodenectomy in patients with ductal adenocarcinoma of the pancreatic head

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Hepatobiliary & Pancreatic Diseases International 2021年第3期20卷 271-278页

作者： Andreas Minh Luu Chris Braumann Orlin Belyaev Monika Janot-Matuschek Henrik rudolf Michael Praktiknjo Waldemar Uhl Department of General and Visceral Surgery St.Josef HospitalRuhr University BochumGudrunstrasse 56Bochum 44791Germany Department of Medical Informatics Biometry and EpidemiologyRuhr University BochumUniversitaetsstrasse 105Bochum 44789Germany Department of Internal Medicine University of BonnVenusberg-Campus 1Bonn 53127Germany

Background: Pancreatic ductal adenocarcinoma(PDAC) has the worst prognosis of all malignant tumors due to unavailable screening methods, late diagnosis with a low proportion of resectable tumors and resistance to systemic treatment. Complete tumor resection remains the cornerstone of modern multimodal strategies aiming at long-term survival. This study was performed to investigate the overall rate of long-term survival(LTS) and its contributing factors. Methods: This was a retrospective single-center analysis of consecutive patients undergoing pancreaticoduodenectomy(PD) for PDAC between 2007 and 2014 at the St. Josef Hospital, Ruhr University Bochum, Germany. Clinical and laboratory parameters were assessed and evaluated for prediction of LTS with Cox regression analysis. Results: The overall rate of LTS after PD for PDAC was 20.4%(34/167). Median survival was 24 months regardless of adjuvant treatment. Carbohydrate antigen 19-9 levels, tumor grade, lymph vessel invasion, perineural invasion and reduced general condition were significantly associated with LTS in univariate analysis( P<0.05). Serum levels of carbohydrate antigen 19-9, American Joint Committee on Cancer stage, tumor grade, abdominal pain, male, exocrine pancreatic insufficiency and duration of postoperative hospital stay were independent predictors of cancer survival in multivariable analysis. Conclusions: Cancer related characteristics are associated with LTS in multimodally treated patients after curative PDAC surgery.

关键词： Pancreaticoduodenectomy Whipple’s procedure Pancreatic cancer survival Ductal adenocarcinoma Pancreas Pancreatic surgery

Assessment of the thermal effect of large industrial buildings on permafrost foundation soils in Yakutsk

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Research in Cold and Arid Regions 2023年第6期15卷 262-267页

作者： rudolf V.Zhang Stanislav I.Zabolotnik Pavel S.Zabolotnik Melnikov Permafrost Institute SB RAS Yakutsk 677010Russia

The results of monitoring studies of the ground thermal state beneath the Yakutsk Combined Heat and Power Plant buildings are presented in order to determine their structural stability and the possibility of further troublefree operation of the entire complex of the *** main causes for the formation of water-bearing taliks under and adjacent to the buildings are presented,and the factors influencing the existing geocryological situation are *** continuing stable state of the buildings demonstrates the possibility of using two construction principles on permafrost at one site,including preserving permafrost and accommodating permafrost thawing.

关键词： Yakutsk Combined Heat and Power Plant Permafrost Talik Ground temperature

Safety of small and medium dams in permafrost regions

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Research in Cold and Arid Regions 2014年第4期6卷 331-339页

作者： rudolf V.Zhang Sergey A.Velikin Melnikov Permafrost Institute Siberian Branch of the Russian Academy of SciencesYakutsk 677010 Russia Vilyui Permafrost Research Station Melnikov Permafrost Institute Siberian Branch of the Russian Academy of SciencesChernyshevsky 678185 Russia

Safe operation and performance of dams is one of the key issues in permafrost regions. At present, the existing dams are 40–45 years old and they are reaching their design life limit. Intensive geocryological processes（thermokarst, thermal erosion, frost heaving, suffosion, concentrated seepage along the voids left by melt ice and others） begin to develop at the early stages of construction. These processes are even more intensive under severe climatic conditions of the permafrost zone due to the large thermal and moisture gradients and the resulting complex thermal stress-strain state in the structures. Determining safety criteria is a critical and difficult task in dam safety management. The existing procedures need to be continuously refined and improved depending on dam importance class. Some researchers recommend introducing process development criteria（stability, destabilization, and extremality） for more objective assessment of dam safety, in addition to the existing two condition criteria. In other words, they call for a multi-factor dam – environment interaction system. A case study of safety declaration for an existing dam is presented.

关键词： permafrost dam safety hydraulic structure geocryological process safety criteria safety declaration

A brief review of genome editing technology for generating animal models

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Frontiers of Agricultural Science and Engineering 2020年第2期7卷 123-128页

作者： Haoyi WANG Sen WU Mario R.CAPECCHI rudolf JAENISCH State Key Laboratory of Stem Cell and Reproductive Biology Institute of ZoologyChinese Academy of SciencesBeijing 100101China University of the Chinese Academy of Sciences Beijing 100049China Institute for Stem Cell and Regeneration Chinese Academy of SciencesBeijing 100101China Beijing Advanced Innovation C enter for Food Nutrition and Human Health China Agricultural UniversityBeijing 100193China State Key L aboratory of Agrobiotechnology College of Biological SciencesChina Agricultural UniversityBeijing 100193China Departm ent of Human Genetics University of Utah School of MedicineSalt Lake CityUT 84112USA Whitehead Institute for Biomedical Research CambridgeMA 02142USA Departm ent of Biology Massachusetts Institute of TechnologyCambridgeMA 02142USA

The recent development of genome editing technologies has given researchers unprecedented power to alter DNA sequences at chosen genomic loci,thereby generating various genetically edited animal *** mini-review briefly summarizes the development of major genome editing tools,focusing on the application of these tools to generate animal models in multiple species.

关键词： animal model CRISPR genome editing TALEN ZFN

Natural Hazard Preventinkon and the Mountain Land Risk Reduction in the Western Carpathians

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Journal of Mountain Science 2005年第3期2卷 202-210页

作者： Peter Maas rudolf Ondráik Libor Jansky Department of Engineering Geology Faculty of Natural Sciences Comenius University Mlynská dolina G 842 15 Bratislava SlovakiaDepartment of Engineering Geology Faculty of Natural Sciences Comenius University Mlynská dolina G 842 15 Bratislava SlovakiaEnvironment and Sustainable Development Programme United Nations University Tokyo 150-8925 Japan

The Western Carpathians are located out of world main natural hazardous zones. Human casualties are related more to snow avalanches in connection with mountain hiking, some individuals yearly by flooding and rarely by forest fires. Economic lost about 0.1 to 0.2 %, exceptionally up to 0.8 % of the gross domestic product (GDP) proportionally to the Carpathian regions of particular countries. Natural disasters are linked, except of the above mentioned events, to infrequent small and medium scale earthquakes, landslides, and erosion. Records of the most harmful natural events are found in archives since the 16th century. Their systematic study and factor analysis started from the end of the 19th century, and protective measures and organization of impact mitigation developed during the 20th century to minimize the risk.

关键词： Natural hazards Western Carpathians Slovakia

Gonadal damage and options for fertility preservation in female and male cancer survivors

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Asian Journal of Andrology 2006年第5期8卷 515-533页

作者： Theodoros Maltaris Heinz Koelbl rudolf Seufert Franklin Kiesewetter Matthias W. Beckmann Andreas Mueller Ralf Dittrich Department of Obstetrics and Gynecology Johannes Gutenberg University Mainz D-55124 Germany Division of Andrology Erlangen University Hospital University of Erlangen-Nuremberg Erlangen Germany Department of Obstetrics and Gynecology Erlangen University Hospital University of Erlangen-Nuremberg Erlangen Germany

It is estimated that in 2010, 1 in every 250 adults will be a childhood cancer survivor. Today, oncological surgery, radiotherapy and chemotherapy achieve relatively high rates of remission and long-term survival, yet are often detrimental to fertility. Quality of life is increasingly important to long-term survivors of cancer, and one of the major quality-of-life issues is the ability to produce and raise normal children. Developments in the near future in the emerging field of fertility preservation in cancer survivors promise to be very exciting. This article reviews the published literature, discusses the effects of cancer treatment on fertility and presents the options available today thanks to advances in assisted-reproduction technology for maintaining fertility in male and female patients undergoing this type of treatment. The various diagnostic methods of assessing the fertility potential and the efficacy of in vitro fertilization （IVF） after cancer treatment are also presented.

关键词： reproduction cryopreservation male infertility semen preservation fertility preservation cancer treatment ovarian tissue

Hepatotoxicity of NONI juice: Report of two cases

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World Journal of Gastroenterology 2005年第30期11卷 4758-4760页

作者： Vanessa Stadlbauer Peter Fickert Carolin Lackner Jutta Schmerlaib Peter Krisper Michael Trauner rudolf E Stauber Department of Internal Medicine Institute of Pathology

NONI juice (Morinda citrifolia) is an increasingly popular wellness drink claimed to be beneficial for many *** overt toxicity has been reported to date. We present two cases of novel hepatotoxicity of NONI juice. Causality of liver injury by NONI juice was asses-sed. Routine laboratory tests and transjugular or percutaneous liver biopsy were performed. The first patient underwent successful liver transplantation while the second patient recovered spontaneously after cessation of NONI juice.A 29-year-old man with previous toxic hepatitis associated with small doses of paracetamol developed sub-acute hepatic failure following consumption of 1.5 L NONI juice over 3 wk necessitating urgent liver transplantation. A 62-year-old woman without evidence of previous liver disease developed an episode of self-limited acutehepatitis following consumption of 2 L NONI juice for over 3 mo. The most likely hepatotoxic components of Morinda citrifolia were anthraquinones. Physicians should be aware of potential hepatotoxicity of NONI juice.

关键词： Herbal hepatotoxicity Drug-induced hepatitis NONI juice Acute liver failure