检索结果-南通市图书馆

同方期刊数据库

Functions of nuclear factor Y in nervous system development,function and health

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第10期20卷 2887-2894页

作者： Pedro Moreira roger Pocock Development and Stem Cells Program Monash Biomedicine Discovery Institute and Department of Anatomy and Developmental BiologyMonash UniversityMelbourneVICAustralia

Nuclear factor Y is a ubiquitous heterotrimeric transcription factor complex conserved across eukaryotes that binds to CCAAT boxes,one of the most common motifs found in gene promoters and *** the last 30 years,research has revealed that the nuclear factor Y complex controls many aspects of brain development,including differentiation,axon guidance,homeostasis,disease,and most recently ***,a complete understanding of transcriptional regulatory networks,including how the nuclear factor Y complex binds to specific CCAAT boxes to perform its function remains *** this review,we explore the nuclear factor Y complex’s role and mode of action during brain development,as well as how genomic technologies may expand understanding of this key regulator of gene expression.

关键词： axon guidance CCAAT boxes neuronal degeneration neuronal differentiation neuronal regeneration nuclear factor Y complex transcription factor transcriptional regulation

Long-Time Turbulence Model Deduced from the Navier-Stokes Equations

在线全文

学校读者我要写书评

暂无评论

Chinese Annals of Mathematics,Series B 2015年第5期36卷 883-894页

作者： roger LEWANDOWSKI IRMAR and Fluminance Team University of Rennes 1 and INRIA Campus Beaulieu

The author shows the existence of long-time averages to turbulent solutions of the Navier-Stokes equations and determines the equations satisfied by them, involving a Reynolds stress that is shown to be dissipative.

关键词： Navier-Stokes equations Weak solutions Turbulence modeling Reynolds stress

Real-life chromoendoscopy for dysplasia surveillance in ulcerative colitis

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2018年第35期24卷 4069-4076页

作者： Pasquale Klepp Anita Tollisen Arne roseth Milada Cvancarova Smastuen Solveig N Andersen Morten Vatn Bjorn A Moum Stephan Brackmann Unger-Vetlesen Institute Department of Internal MedicineLovisenberg Diaconal HospitalOslo 0456Norway Institute of Clinical Medicine University of OsloOslo 0317Norway Department of Pathology Akershus University HospitalLorenskog 1474Norway Department of Gastroenterology Oslo University HospitalOslo 0450Norway Department of Gastroenterology Akershus University HospitalLorenskog 1474Norway

AIM To evaluate the use of chromoendoscopy for surveillance of ulcerative colitis in a real-life community hospital *** Patients with extensive ulcerative colitis, having disease duration of more than 8 years and who presented between the years of 1999 to 2013, were offered enrolment in this single cohort prospective study. All participants underwent standard bowel preparation with sodium phosphate and chromoendoscopy. Two expert endoscopists, novice to chromoendoscopy, evaluated each segment of the colon with standarddefinition colonoscopes after spray application of 0.4% indigo carmine. All observed lesions were recorded and evaluated before being removed and/or biopsied. In addition, nontargeted biopsies were taken from each segment of the colon. The dysplasia detection rate and dysplasia detection yield were ascertained. RESULTS A total of 21 neoplastic lesions(2 carcinomas, 4 of high-grade dysplasia and 15 of low-grade dysplasia) and 27 nondysplastic lesions were detected in 16 of the total 67 patients(70% male; median disease duration: 17 years; median age at diagnosis: 25 years; 92% aminosalicylate-treated). The dysplasia detection rate was 10.5%(7/67 patients). The dysplasia detection yield was 20.8%(10/48) for targeted biopsies and 3.5%(11/318) for nontargeted biopsies. The sensitivity and specificity for the macroscopic evaluation of neoplasia using chromoendoscopy were 48% [95% confidence interval(CI): 26%-70%] and 96%(95%CI: 93%-98%), respectively. The positive predictive and negative predictive values were 42%(95%CI: 27%-59%) and 97%(95%CI: 95%-98%), respectively. A total of 19/21 dysplastic lesions were detected in mucosa with histologic *** Chromoendoscopy seems to be of value for dysplasia surveillance of ulcerative colitis in a community hospital setting. The yield of non-targeted biopsies is negligible.

关键词： Colorectal cancer Dysplasia Ulcerative colitis Surveillance Chromoendoscopy

Design of Feedwater Heaters for the AM600 Turbine Island

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Energy and Power Engineering 2018年第10期12卷 461-476页

作者： roseth Senosi Robert M. Field KEPCO International Nuclear Graduate School 658-91 Haemaji-ro Seosaeng-myeon Ulju-gun Ulsan 689-882 Republic of Korea

The Advanced Modern 600 MWe (AM600) project represents the conceptual mechanical design and layout of a Nuclear Power Plant (NPP) Turbine Island intended to address challenges associated with emerging markets interested in nuclear power. The biggest challenge relates to project financing and the subsidiary issue of maintaining the construction schedule. To address that challenge in part, the AM600 is designed with a single cylinder low pressure turbine rotor matched to a condenser module. The module integrates all low pressure Feedwater Heaters (FWHs) into the condenser neck. This study investigates the design and sizing of a single string of FWHs to demonstrate proof-of-concept of the AM600 design. Specifically, the condenser is designed as a factory fabricated module which includes the installed low pressure FWHs along with major piping and valving. The analysis and design summarized here demonstrate that using industry standards and guidelines, along with accepted engineering practices, the AM600 can accommodate a modular condenser design while allowing for continued operation with an FWH Out-of-Service (OOS).

关键词： AM600 FWH HEI medium size reactor NPP PEPSE OOS TEMA Turbine Island

A Relative Theory for Leibniz n-Algebras

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Algebra Colloquium 2016年第2期23卷 219-226页

作者： Guy roger Biyogmam Department of Mathematics Southwestern Oklahoma State University 100 Campus Drive Weatherford OK 73096 USA

In this paper we show that for an n-Filippov algebra g, the tensor power g ^n-1 is endowed with a structure of anti-symmetric co-representation over the Leibniz algebra g ^n-1. This co-representation is used to define some relative theories for Leibniz n-algebras with n 〉 2 and obtain exact sequences relating them. As a result, we construct a spectral sequence for the Leibniz homology of Filippov algebras.

关键词： Leibniz n-algebras Filippov algebras Leibniz homology

Correction of disturbed pathophysiology of hepatic failure by albumin dialysis

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Hepatobiliary & Pancreatic Diseases International 2008年第1期7卷 19-24页

作者： roger Williams Institute of Hepatology University College London Medical School 69-75 Chenies MewsLondonWC1E 6HXUK

Introduction In my presentation to the 4th International Symposium on Hepatic Failure and Artificial Liver Support in Chongqing on which this paper is based, I was specifically asked to address the question of whether albumin dialysis, as in the Molecular Adsorbents Recirculating System (MARS) did correct known abnormalities of the disturbed pathophysiology in liver failure. Before doing this

关键词： albumin dialysis

Archaeal viruses-novel,diverse and enigmatic

在线全文

学校读者我要写书评

暂无评论

Science China(Life Sciences) 2012年第5期55卷 422-433页

作者： GARRETT roger A Archaea Centre Department of BiologyCopenhagen UniversityOle Maal esVej 5DK2200 Copenhagen NDenmark

Recent research has revealed a remarkable diversity of viruses in archaeal-rich environments where spindles, spheres, fila- ments and rods are common, together with other exceptional morphotypes never recorded previously. Moreover, their dou- ble-stranded DNA genomes carry very few genes exhibiting homology to those of bacterial and eukaryal viruses. Studies on viral life cycles are still at a preliminary stage but important insights are being gained especially from microarray analyses of viral transcripts for a few model virus-host systems. Recently, evidence has been presented for some exceptional archaeal- nspecific mechanisms for extra-cellular morphological development of virions and for their cellular extrusion. Here we sum- marise some of the recent developments in this rapidly developing and exciting research area.

关键词： virus morphotypes diversity and evolution life cycle temporal regulation cellular extrusion mechanism

SOME REMARKS ON HYDROFOIL CAVITATION

在线全文

学校读者我要写书评

暂无评论

Journal of Hydrodynamics 2012年第3期24卷 305-314页

作者： ARNDT roger E. A. Saint Anthony Falls Laboratory University of Minnesota MinneapolisMN 55414 USA

This paper reviews numerical and experimental investigations of sheet/cloud cavitation carried out at the St. Anthony Falls Laboratory and at two collaborating facilities （Versuchsanstalt Ftir Wasserbau, Obernach, Germany and Osaka University, Japan） for more than a decade. Although significant advances have been made in the analysis of this flow several issues are still unresolved. The purpose of this paper is to examine the overall features of the problem, review the progress made to date and suggest avenues for new investigation.

关键词： cavitation hydrofoil numerical simulations

Multi-agent Control of High Redundancy Actuation

在线全文

学校读者我要写书评

暂无评论

International Journal of Automation and computing 2014年第1期11卷 1-9页

作者： Jessica Davies roger Dixon roger M.Goodall Thomas Stefen Lancaster Environment Centre Lancaster University School of Electrical Electronic & Systems EngineeringLoughborough University Department of Aeronautical and Automotive Engineering Loughborough University

The high redundancy actuator(HRA)concept is a novel approach to fault tolerant actuation that uses a high number of small actuation elements,assembled in series and parallel in order to form a single actuator which has intrinsic fault *** this structure afords resilience under passive control methods alone,active control approaches are likely to provide higher levels of performance.A multiple-model control scheme for an HRA applied through the framework of multi-agent control is presented *** application of this approach to a 10×10 HRA is discussed and consideration of reconfguration delays and fault detection errors are *** example shows that multi-agent control can provide tangible performance improvements and increase fault tolerance in comparison to a passive fault tolerant *** delays are shown to be tolerable,and a strategy for handling false fault detections is detailed.

关键词： Fault tolerance actuators intelligent control redundancy intelligent actuators cooperative systems