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海洋地质 2013年第3期29卷 14-14页

作者： Carlos roberto de SOUZA FILHO Luciola Alves MAGALI-LAES 万荣胜(翻译)

圣弗朗西斯科盆地（巴西中部）有数个烃微渗漏显示，米纳斯吉拉斯州（RcmansodoFogo）是典型区。该区地势平坦，沙质土壤上种植了人工桉树林。

关键词：微渗漏遥感测量光谱响应植被生长巴西多光谱高光谱超光谱

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国际贸易摩擦远未结束

中国房地产金融 2019年第2期 28-28页

作者：罗伯托·阿泽维多世界贸易组织(WTO)

根据世界贸易组织(WTO)发布的“世界贸易景气指数”(WTOI),到2018年第四季度,全球贸易增长可能进一步放缓。WTO预计,2018年全球贸易增长3.9%,2017年前值3.7%,2019年预期3.9%。

关键词：国际贸易摩擦世界贸易组织景气指数贸易增长 WTO

Endoscopic vs radiologic gastrostomy for enteral feeding:A systematic review and meta-analysis

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World Journal of Meta-Analysis 2023年第6期11卷 277-289页

作者： Evellin Souza Valentim dos Santos Guilherme Henrique Peixoto de Oliveira Diogo Turiani Hourneaux de Moura Bruno Salomão Hirsch roberto Paolo Trasolini Wanderley Marques Bernardo Eduardo GuimarãesHourneaux de Moura Department of Gastroenterology Hospital das Clínicas da Faculdade de Medicina da Universidade de São PauloSão Paulo 05403-010Brazil Department of Gastroenterology and Hepatology Hospital Harvard Medical SchoolBostonMA 02115United States

BACKGROUND Percutaneous endoscopic gastrostomy(PEG)and percutaneous radiological gastrostomy(PRG)are minimally invasive techniques commonly used for prolonged enteral *** safe,both techniques may lead to complications,such as bleeding,infection,pain,peritonitis,and tube-related *** literature is unclear on which technique is the *** To establish which approach has the lowest complication *** A database search was performed from inception through November 2022,and comparative studies of PEG and PRG were selected following the Preferred Reporting Items for Systematic Reviews and Meta-analyses *** included studies compared the two techniques directly and provided absolute values of the number of *** with pediatric populations were *** primary outcome of this study was infection and ***,peritonitis,pain,and mechanical complications were secondary *** risk of bias was assessed using the Cochrane risk-of-bias tool for randomized trials(RoB2)and we used The Risk of Bias in Nonrandomized Studies(ROBINS-I)to analyze the retrospective *** also performed GRADE analysis to assess the quality of *** on risk differences and 95%confidence intervals were obtained using the Mantel-Haenszel *** Seventeen studies were included,including two randomized controlled trials and fifteen retrospective cohort *** total population was 465218 individuals,with 273493 having undergone PEG and 191725 *** only outcome that showed a significant difference was tube related complications in retrospective studies favoring PEG(95%CI:0.03 to 0.08;P<0.00001),although this outcome did not show significant difference in randomized studies(95%CI:-0.07 to 0.04;P=0.13).There was no difference in the analyses of the following outcomes:infection in retrospective(95%CI:-0.01 to 0.00;P<0.00001)or randomized(95%CI:-0.06 to 0.04;P=0.44)studies;bleeding in retrospective(95%CI

关键词： Gastrostomy Adverse events Meta-analysis Percutaneous endoscopic Radiological gastrostomy

A Novel Approach to Measure the Total Antioxidant Power of Wines through Near Infrared Spectroscopy and Its Relevance in Human Nutrition

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Journal of Health Science 2019年第4期7卷 209-214页

作者： Raúl Francisco Pastor María Laura Mariani Marianela G. Villach Pablo N. Cascón Miriam Giudice Elena Pastor Isabel Pastor roberto H. Iermoli Alicia B. Penissi Research Institute Faculty of Medical SciencesUniversidad del AconcaguaMendoza M5500CKCArgentina Polyphenols Wine and HealthInternal Medicine IV ChairHospital de ClínicasUniversidad de Buenos AiresCiudad de Buenos Aires C1120AAFArgentina

Wine is the product of the alcoholic fermentation of the grape (Vitis vinifera). As such, it is a hydroalcoholic solution with a variable content of nutritional and functional (polyphenols) molecules, the latter involved in its antioxidant potential. The organoleptic variables of wine, together with its potential positive effects on health of a light-moderate intake, have always been topics of great interest within the cultures. In the label of wine, alcohol is the only declared variable. On the other hand, there is no information about the content of “positive” molecules, such as those associated with the antioxidant power. This value could be very important to classify the wines, helping oenologist and nutritionist in qualifying them as a component of Mediterranean diet. Moreover, one of the most critical aspects in evaluating the role of wine in human health through epidemiological prospective studies is the quality of the products used and their antioxidant potential. This research aimed to optimize and validate an analytical approach based on a portable device (SCIO?), using NIRS (near-infrared reflectance spectroscopy). It allows the measure of TAP (total antioxidant power) of wine through the glass. Research findings are promising. To the best of our knowledge, this is the first time that an easy-to-use and cheap hand-held scanner is validated to measure the TAP of a beverage.

关键词： TAP of wines near-infrared spectroscopy of wines NIRS portable device

Robotic versus laparoscopic liver resection for huge (≥10 cm) liver tumors: an international multicenter propensity-score matched cohort study of 799 cases

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Hepatobiliary Surgery and Nutrition 2023年第2期12卷 205-215,I0005页

作者： Tan-To Cheung Rong Liu Federica Cipriani Xiaoying Wang Mikhail Efanov David Fuks Gi-Hong Choi Nicholas L.Syn Charing C.N.Chong Fabrizio Di Benedetto Ricardo Robles-Campos Vincenzo Mazzaferro Fernando Rotellar Santiago Lopez-Ben James O.Park Alejandro Mejia Iswanto Sucandy Adrian K.H.Chiow Marco V.Marino Mikel Gastaca Jae Hoon Lee TPeter Kingham Mathieu D’Hondt Sung Hoon Choi Robert P.Sutcliffe Ho-Seong Han Chung-Ngai Tang Johann Pratschke roberto I.Troisi Go Wakabayashi Daniel Cherqui Felice Giuliante Davit L.Aghayan Bjorn Edwin Olivier Scatton Atsushi Sugioka Tran Cong Duy Long Constantino Fondevila Mohammad Abu Hilal Andrea Ruzzenente Alessandro Ferrero Paulo Herman Kuo-Hsin Chen Luca Aldrighetti Brian K.P.Goh International robotic and laparoscopic liver resection study group investigators Department of Surgery Queen Mary HospitalThe University of Hong KongHong Kong SARChina Faculty of Hepatopancreatobiliary Surgery The First Medical Center of Chinese People’s Liberation Army(PLA)General HospitalBeijingChina Hepatobiliary Surgery Division IRCCS San Raffaele HospitalMilanItaly Department of Liver Surgery and Transplantation Liver Cancer InstituteZhongshan HospitalFudan UniversityShanghaiChina Department of Hepato-Pancreato-Biliary Surgery Moscow Clinical Scientific CenterMoscowRussia Department of Digestive Oncologic and Metabolic SurgeryInstitute Mutualiste MontsourisUniversite Paris DescartesParisFrance Division of Hepatopancreatobiliary Surgery Department of SurgerySeverance HospitalYonsei University College of MedicineSeoulKorea Department of Hepatopancreatobiliary and Transplant Surgery Singapore General Hospital and Yong Loo Lin School of MedicineNational University of SingaporeSingaporeSingapore Division of Hepatobiliary and Pancreatic Surgery Department of SurgeryPrince of Wales HospitalThe Chinese University of Hong KongHong Kong SARChina HPB Surgery and Liver Transplant Unit University of Modena and Reggio EmiliaModenaItaly Department of General Visceral and Transplantation SurgeryClinic and University Hospital Virgen de la ArrixacaIMIB-ARRIXACAMurciaSpain HPB Surgery Hepatology and Liver TransplantationFondazione IRCCS Istituto Nazionale Tumori di MilanoMilanItaly HPB and Liver Transplant Unit Department of General SurgeryClinica Universidad de NavarraUniversidad de NavarraPamplonaSpain Institute of Health Research of Navarra(IdisNA) PamplonaSpain Hepatobiliary and Pancreatic Surgery Unit Department of SurgeryDr.Josep Trueta HospitalIdIBGiGironaSpain Hepatobiliary Surgical Oncology Department of SurgeryUniversity of Washington Medical CenterSeattleWAUSA The Liver Institute Methodist Dallas Medical CenterDallasTXUSA AdventHealth Tampa Digestive Health InstituteTampaFLUSA Hepatopancreatobiliary Unit Department of SurgeryChangi General

Background:The use of laparoscopic(LLR)and robotic liver resections(RLR)has been safely performed in many institutions for liver tumours.A large scale international multicenter study would provide stronger evidence and insight into application of these techniques for huge liver tumours≥10 ***:This was a retrospective review of 971 patients who underwent LLR and RLR for huge(≥10 cm)tumors at 42 international centers between ***:One hundred RLR and 699 LLR which met study criteria were *** comparison between the 2 approaches for patients with huge tumors were performed using 1:3 propensity-score matching(PSM)(73 vs.219).Before PSM,LLR was associated with significantly increased frequency of previous abdominal surgery,malignant pathology,liver cirrhosis and increased median *** PSM,RLR and LLR was associated with no significant difference in key perioperative outcomes including media operation time(242 vs.290 min,P=0.286),transfusion rate rate(19.2%vs.16.9%,P=0.652),median blood loss(200 vs.300 mL,P=0.694),open conversion rate(8.2%vs.11.0%,P=0.519),morbidity(28.8%vs.21.9%,P=0.221),major morbidity(4.1%vs.9.6%,P=0.152),mortality and postoperative length of stay(6 vs.6 days,P=0.435).Conclusions:RLR and LLR can be performed safely for selected patients with huge liver tumours with excellent *** was no significant difference in perioperative outcomes after RLR or LLR.

关键词： Laparoscopic liver resection(LLR) robotic liver resection(RLR) hepatocellular carcinoma colorectal liver metastases huge

The Administration of Ocoxin Increases the Quality of Life of Patients with Advanced Epithelial or Metastatic Ovarian Cancer Undergoing Neoadjuvant Chemotherapy

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Journal of Cancer Therapy 2022年第9期13卷 561-584页

作者： Karen López Miguel Daniel Ricardo Martínez Ávila Lliset Álvarez Pérez Gisselle Martínez Rabasa Alejandro Linchenat Lambert roberto Esperón Noa Lisandra Heredia Manzano Margarita De Quesada Amigó Rafael I. Reyes Velázquez Danay Corrales Otero Ramon Ropero Toirac Idelmis Curbelo Heredia Mircea Betancourt Cabeza Tania A. Agrelo Ramos Rosa María Muñoz Reyes Juan Jesús Lence Anta Rosalía Fuentes Sosa Karelia Silvera Candó Kirenia Silva Rodríguez Zaida Lastre Sosa Mayte Robaina García Eduardo Sanz David Marquez Department of Medical Oncology INOR La Habana Cuba Department of Gynaeco-Oncology INOR La Habana Cuba Department of Anatomical Pathology INOR La Habana Cuba Department of Imaging INOR La Habana Cuba Clinical Research Section INOR La Habana Cuba Department of Onco-Psychology INOR La Habana Cuba Clinical Laboratory Department INOR La Habana Cuba Clinical Trials Pharmacy Department INOR La Habana Cuba Department of Biostatistics CENCEC La Habana Cuba Scientific Department CATALYSIS Madrid Spain

Background: 70% of ovarian cancer cases are diagnosed at an advanced stage (III or IV) of the disease and, in turn, with a high prevalence of peritoneal carcinosis and ascites, which leads to progressive malnutrition in patients, with the consequent deterioration of their general condition. There is a very important relationship between nutritional status, quality of life, survival, and the ability to tolerate multidisciplinary treatment of peritoneal carcinosis. Methods: A phase II, open-label, single-center, non-randomised clinical trial was conducted that included 36 patients with advanced disease who were administered the nutritional supplement Ocoxin, 30 ml twice a day, beginning one week before chemotherapy (CT) based on carboplatin/paclitaxel, of which they receive three cycles with neoadjuvant intent. Ocoxin treatment was continued during chemotherapy and for three weeks after completion of the last cycle, as well as during any periods for which this treatment was discontinued due to toxicity. The effect of Ocoxin on the quality of life was assessed through the QLQ C30 and QLQ OV28 questionnaires from the start of treatment until the end of the follow-up period. In addition, the Karnofsky Index and nutritional parameters were assessed. Results: There were no significant differences between adverse events versus baseline values, except in leukocytes, lymphocytes, neutrophils, ALT, and AST. There was no deterioration of the QoL scales, except for those related to the effects of chemotherapy and alopecia. Conclusions: Ocoxin as an adjuvant to chemotherapy appears to improve better tolerance to chemotherapy, showed a good safety profile, and improved quality of life. For further information on Ocoxin neoadjuvant therapy benefits, a phase III clinical trial will be needed.

关键词： Chemotherapy Radiotherapy Ovarian Cancer Oncology Quality of Life Ad-juvant Therapy Supportive Care

尼美舒利及其他非甾体类抗炎药物肝毒性的队列研究

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英国医学杂志中文版 2004年第3期7卷 190-190页

作者： Giuseppe Traversa Clara Bianchi roberto Da Cas Iosief Abraha Francesca Menniti-Ippolito Mauro Venegoni 李伟

目的:与其他非甾体类抗炎药物相比较,评价尼美舒利(nimesulide)急性肝毒性的危险性。设计:回顾性队列研究和巢式病例对照研究。地点:意大利翁布里亚地区(Umbria region)。参与者:1997年1月～2001年12月31日间400000例当前、近期或者... 详细信息

目的:与其他非甾体类抗炎药物相比较,评价尼美舒利(nimesulide)急性肝毒性的危险性。设计:回顾性队列研究和巢式病例对照研究。地点:意大利翁布里亚地区(Umbria region)。参与者:1997年1月～2001年12月31日间400000例当前、近期或者过去应用过非甾体类抗炎药物者(近2百万个处方)。

关键词：尼美舒利非甾体类抗炎药药物毒性肝损伤

长期交通相关空气污染暴露与亚临床动脉粥样硬化的关联:REGICOR研究

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环境与职业医学 2013年第5期30卷 387-387页

作者： Marcela Rivera Xavier Basagaa Inmaculada Aguilera Maria Foraster David Agis Eric de Groot Laura Perez Michelle A.Mendez Laura Bouso Jaume Targa Rafael Ramos Joan Sala Jaume Marrugat roberto Elosua Nino Künzli

[背景]长期空气污染暴露对动脉粥样硬化形成慢性过程影响的流行病学证据并不多。[目的]通过测量颈动脉内膜中层厚度（IMT）和踝臂指数（ABI），探讨长期交通相关空气污染暴露与亚临床动脉粥样硬化的关联。[方法]采用REGICOR（RegistreGi... 详细信息

[背景]长期空气污染暴露对动脉粥样硬化形成慢性过程影响的流行病学证据并不多。[目的]通过测量颈动脉内膜中层厚度（IMT）和踝臂指数（ABI），探讨长期交通相关空气污染暴露与亚临床动脉粥样硬化的关联。[方法]采用REGICOR（RegistreGironidelCor：赫罗纳心脏病注册）研究中2780名参加者复检期间（2007--2010年）的数据进行横断面分析，REGICOR是在西班牙赫罗纳进行的、以人群为基础的前瞻性队列研究。

关键词：亚临床动脉粥样硬化空气污染交通颈动脉内膜中层厚度动脉粥样硬化形成前瞻性队列研究踝臂指数横断面分析

ERp44-peroxiredoxin 4复合物晶体结构揭示巯基介导蛋白质内质网滞留的分子机制

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科学新闻 2017年第4期 182-182页

作者： Kai Yang De-Feng Li Xi'e Wang Jinzhao Liang roberto Sitia 王志珍王曦中国科学院生物物理研究所中国科学院第三世界科学院

文章简介真核细胞中,分泌蛋白和膜蛋白的折叠组装和转运受到质量控制系统严谨的调控。分子伴侣ERp44能够在早期分泌途径中与多种蛋白形成分子间二硫键实现后者在内质网腔的滞留。ERp44如何识别其滞留的目标蛋白以及形成分子间二硫键的... 详细信息

文章简介真核细胞中,分泌蛋白和膜蛋白的折叠组装和转运受到质量控制系统严谨的调控。分子伴侣ERp44能够在早期分泌途径中与多种蛋白形成分子间二硫键实现后者在内质网腔的滞留。ERp44如何识别其滞留的目标蛋白以及形成分子间二硫键的氧化力来源尚不清楚。本研究解析了ERp44与peroxiredoxin 4(Prx4)复

关键词：蛋白质 ERp44-peroxiredoxin 4 中国科学院生物物理研究所生物大分子国家重点实验室复合物晶体结构结晶构造固体结构分子机制内质网介导巯基

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瑞吉欧学校

现代装饰 2023年第2期 86-91页

作者： Andrés Jaque roberto Gonzalez Garcia Luis Gonzalez Cabrera Alberto Heras Ismael Medina Manzano Jesus Meseguer Cortés Paola Pardo-Castillo Rajvi Anandpara Juan David Barreto Ines Barros Ludovica Battista Shubhankar Bhajekar Elise Durand Drishti Gandhi Maria Karagianni Bansi Mehta Alessandro Peja Meeerati Rana Mishti Shah Saumil Shanghavi JoséHevia(摄影) 范嘉苑(编译) 不详

瑞吉欧学校(Reggio School)的设计理念是通过建筑环境来激发孩子们的探索和求知欲。因此,该建筑被视作一个复杂的生态系统,让孩子们在通过自我驱动的集体实验过程中引导自身教育,这也遵循了罗里斯·马拉古奇(Loris Malaguzzi)和意大利... 详细信息

瑞吉欧学校(Reggio School)的设计理念是通过建筑环境来激发孩子们的探索和求知欲。因此,该建筑被视作一个复杂的生态系统,让孩子们在通过自我驱动的集体实验过程中引导自身教育,这也遵循了罗里斯·马拉古奇(Loris Malaguzzi)和意大利吉欧·艾米利亚市当地家长共同提出的教育理念,旨在增强孩子们应对不可预测挑战和潜在风险的能力。从该建筑的设计、建造到使用,都旨在超越可持续的范式,并将生态作为一种路径,继而将环境影响、多种群类别、物质动态化、集体治理以及教学方法通过建筑相交汇。

关键词：瑞吉欧艾米利亚环境影响教学方法生态系统不可预测教育理念自我驱动