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水科学进展 2000年第4期11卷 463-469页

作者：任立良刘新仁河海大学水文水资源及环境学院江苏南京210098

回顾了数字高程模型 ( DEM)数据的信息提取方法 ,阐述了由 DEM提取的信息在水文水资源领域应用的现状。

关键词：数字化数字高程模型地理信息系统水文模型

Allergy march of Chinese children with infantile allergic symptoms: a prospective multi-center study

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World Journal of Pediatrics 2017年第4期13卷 335-340页

作者： Qi Gao Yi-xin ren Yong-Ge Liu Lin Ma Xiao-Hong Gu Wei-Xi Zhang Li Liu Xiao-Jia Zhai Li Xiang Kun-Ling Shen Allergy Department Beijing Children's HospitalCapital Medical University Dermatology Department Beijing Children's HospitalCapital Medical University Pediatric Department People's Hospital of Wuxi CityJiangsu Province Respiratory Medicine Department Yuying Children's Hospital Affiliated to Wenzhou Medical College Pediatric Department the First Hospital of Jilin University Pediatric Department Xinhua Hospital Affiliated to Medicine School of Shanghai Jiaotong University National Clinical Medical Research Center for Respiratory Diseases China

Background:Allergy march refers to progression of allergic diseases from infantile food allergy to the development of asthma and allergic rhinitis (AR).Evidence come mostly from studies in European *** study aimed to investigate allergy march in Chinese children with infantile food protein allergy (FPA) with a special focus on the effect of different formula ***:From 2008 to 2010,153 infants diagnosed with FPA were recruited in five tertiary hospitals across *** were randomly treated with amino-acid-based formula or soy-protein-based formula for a period of 3 ***-term follow-up was performed when they reached early school age,using questionnaires,physical examinations,and serum-specific immunoglobulin ***:The overall follow-up rate was 73.20%.In patients who reached their early school years,the prevalence of physician-diagnosed AR and asthma were 43.75% and 23.21%,*** 40% of the subjects remained positive for food sensitizations upon ***-six subjects receiving aeroallergen screening tests in infancy all proved negative,but upon follow-up,65.57% were sensitized to aeroallergens (P=0.005).No significant difference between the effects of amino-acid-based formula and soy-protein-based formula on children's allergy march was ***:A high proportion (47.32%) of Chinese infants with early allergic symptoms developed respiratory allergies by their early school *** food-sensitized infants outgrew their condition several years later,but then aeroallergen sensitization often ***-acid-based formula showed no advantages over soy protein-based formula with respect to arresting the allergy march.

关键词： allergic rhinitis allergy march asthma atopic dermatitis infant

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企业竞合行为选择与得益关系的对局模拟研究

系统工程理论与实践 2007年第7期27卷 34-40页

作者：项保华任新建复旦大学管理学院上海200433

为了探索企业间竞合行为的不同选择,对于它们最终得益的影响,通过有实际经理人参与的重复囚徒困境对局实验,模拟企业多次重复博弈行为,发现企业竞合博弈对局后期,由于缺乏后续报复手段,导致得益显著降低;"一报还一报(TFT)"策略的对局得... 详细信息

为了探索企业间竞合行为的不同选择,对于它们最终得益的影响,通过有实际经理人参与的重复囚徒困境对局实验,模拟企业多次重复博弈行为,发现企业竞合博弈对局后期,由于缺乏后续报复手段,导致得益显著降低;"一报还一报(TFT)"策略的对局得益明显高于其他策略;背叛行为,无论是单方背叛还是双方背叛,都会对最终得益产生消极影响;最终得益与对局稳定性、对局时间表现出了显著的负相关关系,从而证实了企业竞合行为的不同选择,对于最终得益有显著影响.

关键词：竞合行为得益肿策略重复囚徒困境

以地形为基础的流域水文模型——TOPMODEL及其拓宽应用

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水科学进展 2000年第3期11卷 296-301页

作者：郭方刘新仁任立良水利部南京水文水资源研究所江苏南京210024 河海大学江苏南京210098

介绍了 TOPMODEL的基本理论与理论基础及模型利用地形指数的不同空间分布 ,模拟水文响应的特性。由于以往 TOPMODEL的应用只限于山坡尺度范围 ,本文试探将其应用范围拓宽 ,选择淮河流域为例 ,考察其在一般流域上的应用效果 ,并将 TOPMO... 详细信息

介绍了 TOPMODEL的基本理论与理论基础及模型利用地形指数的不同空间分布 ,模拟水文响应的特性。由于以往 TOPMODEL的应用只限于山坡尺度范围 ,本文试探将其应用范围拓宽 ,选择淮河流域为例 ,考察其在一般流域上的应用效果 ,并将 TOPMODEL与新安江模型作了初步分析比较。

关键词： TOPMODEL 流域水文模型地形指数

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公路桥梁车辆荷载截尾分段概率模型及应用

中国公路学报 2017年第6期30卷 260-267页

作者：赵少杰任伟新中南大学土木工程学院湖南长沙410075 湖南省交通规划勘察设计院湖南长沙410008 中南公路建设及养护技术湖南省重点实验室湖南长沙410008 合肥工业大学土木与水利工程学院安徽合肥230009

为了准确描述实际公路桥梁车辆荷载多峰厚尾的分布特征,利用分段函数结合多个高斯分布函数,并采用数据拟合方法,求得了车辆荷载的概率密度函数和概率分布函数表达式,建立了车辆荷载的分段截尾的多重混合高斯概率分布模型,并进一步推导... 详细信息

为了准确描述实际公路桥梁车辆荷载多峰厚尾的分布特征,利用分段函数结合多个高斯分布函数,并采用数据拟合方法,求得了车辆荷载的概率密度函数和概率分布函数表达式,建立了车辆荷载的分段截尾的多重混合高斯概率分布模型,并进一步推导了基于EM算法的多重混合高斯分布模型求解方法。根据中国实测车辆荷载的轴组特征,获得了各典型地区该分段截尾车辆荷载模型的概率分布参数。分析结果表明:该分布函数模型的拟合精度较高,能准确反映荷载分布的多峰厚尾特征;各典型地区车辆荷载轴质量分布呈现不同特点,但各地区单轴质量的首峰分布基本一致,各轴组荷载普遍超载,特别是贵州、湖北和湖南地区超载较严重;各地区双联轴、三联轴的平均轴质量超出汽车国标规定值约2倍,双联轴平均轴质量超出现行公路工程规范标准值的15%以上;实测数据显示三联轴在95%保证率下的平均轴质量约为50t。

关键词：桥梁工程公路桥梁概率分布模型 EM算法车辆荷载高斯分布轴组

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高温高压容器封头安装中螺柱应力试验

核动力工程 2011年第3期32卷 122-126页

作者：谢林君任欣浙江工业大学化工过程机械研究所杭州310014

针对高温高压容器封头法兰连接中,加载后螺柱预紧力分布不均匀问题,提出在螺柱表面粘贴电阻应变片测量螺柱应变变化的测试过程与基本操作方法。采用正弦模型和指数衰减模型预测螺柱应力的变化,以探索适合的预紧方式和制定合理预紧程序... 详细信息

针对高温高压容器封头法兰连接中,加载后螺柱预紧力分布不均匀问题,提出在螺柱表面粘贴电阻应变片测量螺柱应变变化的测试过程与基本操作方法。采用正弦模型和指数衰减模型预测螺柱应力的变化,以探索适合的预紧方式和制定合理预紧程序。对试验数据的分析结果表明,螺柱的应力沿法兰周向成正弦规律变化;单根螺柱应力在预紧过程中满足指数衰减规律。

关键词：预紧方法螺柱应力试验分析数据拟合

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基于递归矩阵奇异熵的损伤识别方法

振动与冲击 2012年第3期31卷 60-63页

作者：杨栋任伟新中南大学土木建筑学院长沙410075 高速铁路建造技术国家工程实验室长沙410075

对递归图方法在土木工程结构损伤检测中的适用性进行研究,对环境激励的结构响应信号采用多变量融合的方法,并扩展到高维相空间中,研究信号在高维空间中临近点的分布规律和运动特点,采用递归图理论,结合奇异熵理论提出一个新的递归量化... 详细信息

对递归图方法在土木工程结构损伤检测中的适用性进行研究,对环境激励的结构响应信号采用多变量融合的方法,并扩展到高维相空间中,研究信号在高维空间中临近点的分布规律和运动特点,采用递归图理论,结合奇异熵理论提出一个新的递归量化指标——递归矩阵的奇异熵,将其作为损伤敏感特征指标,用于结构的损伤识别。数值算例验证了该指标的有效性。

关键词：相空间递归图递归量化分析奇异熵损伤识别

Treponema pallidum-specific antibody expression for the diagnosis of different stages of syphilis

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Chinese Medical Journal 2013年第2期126卷 206-210页

作者： SUN Ran LAI Di-hui ren Rong-xin LIAN Shi ZHANG Hai-ping Department of Dermatology and Venereology Xuanwu HospitalCapital Medical Universitw Beiiing 100053 China Department of Dermatology and Venereology Chinese Academyof Medical Sciences and Peking Union Medical College Beijing100730 China Department of Dermatology and Venereology Capital MedicalUniversity Beijing 100069 China

Background Tp15, Tp17, Tp45, and Tp47 are outer-membrane proteins found in Treponema pallidum, the etiologic agent of syphilis. These proteins are potent antigens and are potential markers for the serological detection of syphilis. The present study analyzed antibodies to these protein antigens （TP-IgM and TP-IgG） in human serum and investigated the expression of these antibodies during different stages of syphilis. Methods Serum samples were collected from 69 subjects （male 45, female 24） diagnosed with syphilis and analyzed by Western blotting for the expression of IgM and IgG against the four protein antigens. Expression levels of the target antibodies were compared during the same stage of syphilis as well as between different stages of this disease. Results In subjects with primary syphilis, the positive rate of Tp45 IgM was higher than that of other TP-IgM. Tp15 IgM was detected only in subjects with tertiary syphilis. Similarly, the seroprevalence of Tp45 IgG in primary syphilis was higher than for other TP-IgG. No target TP-IgM was detected in subjects with latent syphilis. In subjects with secondary syphilis, the expression level of Tp15 IgG （138.73±20.16） was higher than for other target TP-IgG. In subjects with tertiary syphilis, all target TP-IgG were detected. In subjects with tertiary or latent syphilis, the expression levels of Tp45 IgG （121.33±11.04 and 110.10±40.19, respectively） were higher than those of other target TP-IgG. The expression levels of all Tp-lgM were similar before or after anti-syphilis treatment. In comparison, the expression levels of all TP-IgG decreased compared with the pre-treatment levels, and this decrease was statistically significant （both P 〈0.05） for Tp17 IgG and Tp47 IgG. Conclusions After Treponema pallidum infection, Tp45 IgM appeared first and Tp15 IgM occurred during later stages. The positive rates of all TP-IgG increased with the duration of this disease. Anti-syphilis treatment reduced the expression levels of Tp

关键词： Treponema pallidum Western blotting, syphilis

Epigenetic Modification in Oocyte and Preimplantation Embryonic Development

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Reproductive and Developmental Medicine 2017年第1期1卷 13-17页

作者： Yi-xin ren William Chang Jie Qiao Department of Obstetrics and Gynecology Peking University Third HospitalBeijing 100191China Key Laboratory of Assisted Reproduction Ministry of EducationBeijing 100191China Beijing Key Laboratory of Reproductive Endocrinology and Assisted Reproductive Technology Beijing 100191China Beijing Advanced Innovation Center for Genomics Beijing 100871China Peking-Tsinghua Center for Life Sciences Peking UniversityBeijing 100871China

DNA methylation and histone modification are two of the most characterized epigenetic *** advanced detecting techniques,particularly single-cell sequencing,we can dissect epigenomic patterns and their regulatory roles in the growth and differentiation of gametes and early embryos in animals and *** reproductive technology(ART)procedures have been shown to influence the methylation of certain *** epigenetic regulation may cause several developmental disorders and clinical ***,we describe some concepts in epigenetics and review recent researches on DNA methylation and the histone modification profile and their regulatory roles during early embryo *** also summarize the recent progress in understanding the imprinting disorders associated with ART procedures.

关键词： Assisted Reproductive Technology DNA Methylation Early Embryo Development Histone Modification

磁控溅射TiO_2纳米管阵列与其组装的杂化太阳能电池

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功能材料 2014年第22期45卷 22134-22138页

作者：任鑫曹娇施利毅上海大学纳米科学与技术研究中心材料复合及先进分散技术教育部工程研究中心上海200444

采用直流磁控溅射-热处理二步法在多孔阳极氧化铝模板上制备出TiO2纳米管阵列膜。将纳米管阵列膜转移到ITO导电玻璃,并分别与P3HT和P3HT∶PCBM组装成杂化太阳能电池。通过扫描电镜、X射线衍射仪、能谱仪和模拟太阳光光电性能测试系统化... 详细信息

采用直流磁控溅射-热处理二步法在多孔阳极氧化铝模板上制备出TiO2纳米管阵列膜。将纳米管阵列膜转移到ITO导电玻璃,并分别与P3HT和P3HT∶PCBM组装成杂化太阳能电池。通过扫描电镜、X射线衍射仪、能谱仪和模拟太阳光光电性能测试系统化对TiO2纳米管阵列膜和其组装的太阳能电池进行了分析表征。在纳米管阵列膜和ITO玻璃之间加入TiO2结合层的P3HT∶PCBM基杂化太阳能电池表现出最好的转换效率。该方法制备的大面积TiO2纳米管阵列膜,纯度高、工艺稳定,在未来的聚合物太阳能电池商业化应用中具有巨大潜力。

关键词：直流磁控溅射热处理纳米结构杂化太阳能电池阳极氧化铝模板