检索结果-南通市图书馆

Biomedical and Environmental Sciences 2022年第12期35卷 1150-1155页

作者： LIANG Zhuo Shuai SHI Ji Kang TIAN Yu yang HU Xin Meng ren ya xuan LIU Sai Nan WANG Yu Jian CHENG Yi LIU ya Wen Department of Epidemiology and Biostatistics School of Public HealthJilin UniversityChangchun 130021JilinChina Institute of Translational Medicine The First Hospital of Jilin UniversityChangchun 130021JilinChina

Approximately two-thirds of patients with type 2 diabetes have hypertension. Moreover, blood pressure(BP) increases with hyperglycemia progression. The nexus between prehypertension or hypertension and diabetes entails pathophysiological mechanisms, such as the involvement of the nitricoxide pathway in insulin resistance and the contribution of hyperinsulinemia to sympathetic activity, sodium-fluid retention.

关键词： hypertension involvement diabetes

大户与宗族:明清山东“门”型系谱流变与实践

在线全文

学校读者我要写书评

暂无评论

史林 2021年第1期 99-110,221页

作者：任雅萱山东大学文化遗产研究院 250100

作为宗族分支的"门"型系谱,并非自然分化的结果,而是人群在不同历史阶段有目的地选择联合的结果。通过解读明清时期山东中部"门"型族谱文本和地方志,说明明代中期赋役大户通过分"门"的方式应对差役,并且根据"门"建立宗族。随着清代前期... 详细信息

作为宗族分支的"门"型系谱,并非自然分化的结果,而是人群在不同历史阶段有目的地选择联合的结果。通过解读明清时期山东中部"门"型族谱文本和地方志,说明明代中期赋役大户通过分"门"的方式应对差役,并且根据"门"建立宗族。随着清代前期税收单位从"里甲"到"村庄"的改变,村庄成为税收主体,"门"的等级高低不再是编审户口的依据,但却作为宗族的内部结构保存至今。明清时期"门"型系谱的形成,说明大户分"门"是山东乃至华北宗族的特征之一。

关键词：明清华北 “门”型系谱大户宗族

在线全文

学校读者我要写书评

暂无评论

快速响应的共面转换型液晶显示器

液晶与显示 2017年第9期32卷 685-691页

作者：付明珠郭玉强任亚璇马红梅孙玉宝河北工业大学应用物理系天津300401 河北工业大学电子信息工程学院天津300401

共面转换液晶显示器(IPS-LCD)由于其具有可视角度大、色彩真实、画质出色等优点,在平板显示器中得到了广泛应用,然而响应速度慢限制了其在高端显示器中的应用。本文中,首先通过采用正性液晶,对IPS类型中的边缘场转换型(FFS)和边缘场共... 详细信息

共面转换液晶显示器(IPS-LCD)由于其具有可视角度大、色彩真实、画质出色等优点,在平板显示器中得到了广泛应用,然而响应速度慢限制了其在高端显示器中的应用。本文中,首先通过采用正性液晶,对IPS类型中的边缘场转换型(FFS)和边缘场共面转换型(FIS)的液晶显示器,不同摩擦角度下的电光特性和响应时间进行了模拟计算。然后从预倾角度、电极尺寸以及弹性常数出发,对FIS液晶盒结构参数进行了优化,提出了一种快速响应的液晶显示器。我们通过计算机模拟发现,在FFS液晶盒中,摩擦角度对工作电压具有较大影响,小摩擦角度可实现高透过率、低工作电压;而在FIS液晶盒中,摩擦角度对响应时间具有较大影响,大于10°时与2°时相比,响应速度可提高82.7%以上。并且,不同摩擦角度下,弹性常数对FIS液晶显示器的响应速度影响不同,摩擦角度为2°时,响应速度与弹性常数K11、K22、K33都有关,而摩擦角度为12°时,响应速度只与K22有关,这个原因导致了12°与2°时相比,响应速度提高了84.2%。

关键词： FIS液晶显示器工作电压快速响应

在线全文

学校读者我要写书评

暂无评论

ACSL4基因的功能及其研究进展

中国牛业科学 2020年第5期46卷 52-58页

作者：张依迪任亚轩周军雷初朝党瑞华西北农林科技大学动物科技学院陕西杨凌712100

长链酯酰辅酶A合成酶(long-chain acyl-CoA synthetase,ACSLs)属于多基因家族编码的酶,是机体内脂肪代谢的关键酶,主要催化12~20个碳链长度的脂肪酸、三磷酸腺苷和辅酶A形成长链酰基辅酶A。ACSL4是ACSL家族中的一员,参与对花生四烯酸和... 详细信息

长链酯酰辅酶A合成酶(long-chain acyl-CoA synthetase,ACSLs)属于多基因家族编码的酶,是机体内脂肪代谢的关键酶,主要催化12~20个碳链长度的脂肪酸、三磷酸腺苷和辅酶A形成长链酰基辅酶A。ACSL4是ACSL家族中的一员,参与对花生四烯酸和二十碳五烯酸的调控。本文结合近年来对ACSL4基因作用的研究,就ACSL4在分子育种、癌症治疗、神经发育等方面的作用做出综述,并对今后ACSL4基因的研究工作进行了展望。

关键词： ACSL4 分子育种研究进展

Synthesis of methyl methacrylate star-branched polymer with divinylbenzene as a linking agent via controlled/living photopolymerization

在线全文

学校读者我要写书评

暂无评论

Chinese Chemical Letters 2012年第8期23卷 985-988页

作者： yan yan Cui ya E ren Xiao xuan Liu Department of Polymer Materials and Engineering Faculty of Materials and EnergyGuangdong University of TechnologyGuangzhou 510006China

HTEMPO-functionalized central cores were formed with divinylbenzene in ＇＇core first＇＇ method,and the four or five arms star polymers were built via controlled/living free radical *** four arms star polymers were also prepared with controlled/living free radical photopolymerization in ＇＇arm first＇＇ *** resulting polymers had been confirmed by GPC and 1 H *** showed that the star polymers had low polydispersities and molecular weight（M n） with the 85,000-560,000 g/mol range.

关键词： Controlled/living photopolymerization H-TEMPO Star polymers DVB MMA

Burden of mental disorders and risk factors in the Western Pacific region from 1990 to 2021

在线全文

学校读者我要写书评

暂无评论

World Journal of Psychiatry 2025年第1期15卷 93-105页

作者： ya-Xin Xu Xiao-xuan Niu Wen-Chang Jia Jing Wen Xue-Lin Cheng yan Han Ming-Hui Peng Jing Zhou yao Liu Sun-Fang Jiang Xiao-Pan Li Department of Health Management Centre Zhongshan HospitalFudan UniversityShanghai 200030China Department of General Practice Zhongshan HospitalFudan UniversityShanghai 200030China Department of Nutrition Zhongshan HospitalFudan UniversityShanghai 200032China School of Public Health Fudan UniversityShanghai 200032China

BACKGROUND The burden of mental disorders(MD)in the Western Pacific Region(WPR)re-mains a critical public health concern,with substantial variations across demogra-phics and *** To analyze the burden of MD in the WPR from 1990 to 2021,along with associated risk factors,to reveal changing trends and emerging *** We used data from the Global Burden of Disease 2021,analyzing prevalence,incidence,and disability-adjusted life years(DALYs)of MD from 1990 to *** methods included age-standardisation and uncertainty analysis to address variations in population structure and data *** Between 1990 and 2021,the prevalence of MD rose from 174.40 million cases[95%uncertainty interval(UI):160.17-189.84]to 234.90 million cases(95%UI:219.04-252.50),with corresponding DALYs increasing from 22.8 million(95%UI:17.22-28.79)to 32.07 million(95%UI:24.50-40.68).During this period,the burden of MD shifted towards older age *** and anxiety disorders were predominant,with females showing higher DALYs for depressive and anxiety disorders,and males more affected by conduct disorders,attention-deficit hyperactivity disorder,and autism spectrum ***,New Zealand,and Malaysia reported the highest burdens,whereas Vietnam,China,and Brunei Darussalam reported the ***,childhood sexual abuse and bullying,and intimate partner violence emerged as significant risk *** This study highlights the significant burden of MD in the WPR,with variations by age,gender,and *** coronavirus disease 2019 pandemic has exacerbated the situation,emphasizing the need for a coordinated response.

关键词： Mental disorders Western pacific region Global Burden of Disease Risk factors Disability-adjusted life years

Mechanism of Ascorbic Acid-induced Reversion Against Malignant Phenotype in Human Gastric Cancer Cells

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Biomedical and Environmental Sciences 2006年第5期19卷 385-391页

作者： ya-xuan SUN QIU-SHENG ZHENC GANG LI DE-AN GUO ZI-ren WANG Life Sciences School of Lanzhou University Lanzhou 730000 Gansu China Key Laboratory of Xinjiang Endemic Phytomedicine Resources Ministry of Education Shihezi 832002 Xinjiang China The State Key Laboratory of Natural and Biomimetic Drugs School of Pharmaceutical Sciences Peking University Beijing 100083 China

Objective To find out the mechanisms of redifferentiation and reversion of malignant human gastric cancer cells induced by ascorbic acid. Methods Human gastric cancer cells grown in the laboratory were used. The Trypan blue dye exclusion method was used to determine the cell doubling time. The electrophoresis rate and colonogenic potential were the indices used to measure the rate of redifferentiation. The content of malondialdehyde （MDA） was measured using the thiobarbituric acid （TBA） method. The activities of superoxide dismutase （SOD）, catalase （CAT） and the content of H2O2 were evaluated by spectrophotography. Results Six mmol/L ascorbic acid was used as a positive control. Human gastric cancer cells were treated with 75 μm hydrogen peroxide, which alleviated many of the malignant characteristics. For example, the cell surface charge obviously decreased and the electrophoresis rate dropped from 2.21 to 1.10 pm·s^-1·cm^-1 The colonogenic potential, a measure of cell differentiation, decreased 90.2%. After treatment with ascorbic acid, there was a concentration- and time-dependent increase in hydrogen peroxide （H2O2） and the activity of superoxide dismutase （SOD）. However, the activity of catalase （CAT） resulted in a concentration- and time-dependent decrease. SOD and 3-amino- 1,2,4-triazole （AT） exhibited some effects, but there were statistically significant differences between the SOD and AT group and the H2O2 group, Conclusions Ascurbic acid induces growth inhibition and redifferentiation of human gastric cancer cells through the production of hydrogen peroxide.

关键词： Aminotriazole Ascorbic acid Catalase Gastric cancer Hydrogen peroxide Redifferentiation Superoxide dismutase

Supersymmetric Sawada-Kotera-Ramani Equation: Bilinear Approach

在线全文

学校读者我要写书评

暂无评论

Communications in Theoretical Physics 2008年第3期49卷 685-688页

作者： YU ya-xuan Department of Mathematics Ningbo University Ningbo 315211 China

In this paper, using the Hirota＇s bilineax method, we consider the N = 1 supersymmetric Sawada-Kotera- Ramani equation and obtain the Bazcklund transformation of it. Its one- and two-supersoliton solutions axe obtain... 详细信息

关键词： N = 1 supersymmetric Sawada-Kotera-Ramani equation Backlund transformation supersoliton solutions

Clinical association between coagulation indicators and bone metastasis in patients with gastric cancer

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastrointestinal Oncology 2023年第7期15卷 1253-1261页

作者： xuan Wang Jing-ya Wang Min Chen Juan ren Xin Zhang Department of Radiotherapy and Oncology The First Affiliated Hospital of Xi'an Jiaotong UniversityXi'an 710061Shaanxi ProvinceChina Department of Gastroenterology Xi'an Children's HospitalShaanxi Research Institute for Pediatric DiseasesThe Affiliated Children's Hospital of Xi'an Jiaotong University and National Regional Medical Center for Children(Northwest)Xi'an 710003Shaanxi ProvinceChina Department of Surgical Oncology The First Affiliated Hospital of Xi'an Jiaotong UniversityXi'an 710061Shaanxi ProvinceChina

BACKGROUND Bones are one of the most common target organs for cancer *** evaluation of bone metastasis(BM)status is clinically *** patients often experience a hypercoagulable *** To evaluate the correlation between coagulation indicators and the burden of BM in gastric cancer(GC).METHODS We conducted a single-center retrospective study and enrolled 454 *** information including routine blood examination and coagulation markers were collected before any *** were grouped according to the status of *** operating characteristic curves were used to assess diagnostic performance and determine the optimal cutoff values of the above *** values,sensitivity and specificity were based on the maximum Youden *** and multivariate logistic regression analyses were used to evaluate the relationships between biomarkers and *** Of the 454 enrolled patients,191 patients were diagnosed with *** receiver operating characteristic curve analysis suggested that prothrombin time(PT)Wang X et *** indicators predict bone metastasis WJGO https://*** 1254 July 15,2023 Volume 15 Issue 7[cutoff:13.25;sensitivity:0.651;specificity:0.709;area under receiver operating characteristic curve(AUC)=0.738],activated partial thromboplastin time(aPTT)(cutoff:35.15;sensitivity:0.640;specificity:0.640;AUC=0.678)and fibrin degradation products(FDP)(cutoff:2.75;sensitivity:0.668;specificity:0.801;AUC=0.768)act as novel predictors for *** on multivariate logistic regression analysis,the results showed the independent correlation between PT[odds ratio(OR):3.16;95%confidence interval(CI):1.612-6.194;P=0.001],aPTT(OR:2.234;95%CI:1.157-4.313;P=0.017)and FDP(OR:3.17;95%CI:1.637-6.139;P=0.001)and BM in patients with ***,age,carcinoembryonic antigen,erythrocyte and globulin were found to be significantly associated with *** Coagulation markers,namely PT,aPTT and FDP,mi

关键词： Gastric cancer Bone metastasis Coagulation markers Risk factor Activated partial thromboplastin time Prothrombin time Fibrin degradation products

New Compacton Solutions and Solitary Pattern Solutions for Modified Nonlinearly Dispersive mK(m,n,a,b) Equation

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Communications in Theoretical Physics 2009年第10期52卷 637-640页

作者： YU ya-xuan Department of Applied Mathematics Ningbo University Ningbo 315211 China

In this paper exact solutions of a new modified nonlinearly dispersive equation （simply called inK（m, n, a, b） Ua Ub equation）, u^m-1 ut ＋ α（ u^n）x ＋β（u^a（u^b）xx）x = 0, is investigated by using some direct algorithms. As a result, abundant new compacton solutions （solitons with the absence of infinite wings） and solitary pattern solutions （having infinite slopes or cusps） are obtained.

关键词： mK(m n a b) equation compacton solution solitary pattern solution