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Boundary-lubricated biomaterials with drug delivery for osteoarthritis treatment

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Friction 2024年第10期12卷 2167-2187页

作者： Junyu WU Kaixuan ren Jingbo YIN Department of Polymer Materials School of Materials Science and EngineeringShanghai UniversityShanghai 200444China

The good lubrication ability of articular cartilage holds significant importance in our daily ***(OA),the most prevalent degenerative joint disease,causes cartilage damage,increased friction,and ***,the current clinical treatments for OA exhibit some ***,the sustained drug release systems with lubricating function have attracted considerable attention for treating *** review introduces the lubrication mechanism of cartilage,focusing particularly on the boundary lubrication *** research progress of boundary-lubricated biomaterials with drug delivery,including microcarriers,hydrogels,and nanoparticles in the treatment of OA by improving inter-articular lubrication and relieving inflammation is discussed and *** efficacy and challenges of boundary-lubricated biomaterials with drug delivery in the treatment of OA are summarized,and the prospects are also discussed.

关键词： osteoarthritis joint friction boundary lubrication hydration lubrication drug delivery

一种阴离子交换树脂的制备及其对饮用水原水中硝酸盐的吸附效果

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西安建筑科技大学学报（自然科学版） 2014年第5期46卷 726-730页

作者：任勇翔李梦辕叶媛媛朱菁西安建筑科技大学西北水资源与环境生态教育部重点实验室陕西西安71055 西部建筑科技国家重点实验室(筹) 陕西西安71055

饮用水原水中的硝酸盐污染已引起全球广泛关注.为经济高效地去除饮用水中的硝酸盐,通过1,4-二氯甲氧基丁烷和三乙胺分别对聚苯乙烯交联微球进行氯甲基化和胺化反应,制得了一种大孔型强碱性阴离子交换树脂,并利用傅里叶红外光谱法对其化... 详细信息

饮用水原水中的硝酸盐污染已引起全球广泛关注.为经济高效地去除饮用水中的硝酸盐,通过1,4-二氯甲氧基丁烷和三乙胺分别对聚苯乙烯交联微球进行氯甲基化和胺化反应,制得了一种大孔型强碱性阴离子交换树脂,并利用傅里叶红外光谱法对其化学结构进行了表征.结果表明:制备的离子交换树脂具有良好选择性和再生性,全交换容量为2.4 mmol/g,对硝酸盐静态吸附量为18.34 mg/g,动态吸附量为17.85 mg/g,离子交换柱的穿透时间和泄露时间分别为10 h和12 h,用8%氯化钠反冲再生时间为1 h.

关键词：离子交换树脂合成硝酸盐吸附效果

An effective bimetallic oxide catalyst of RuO_(2)-Co_(3)O_(4) for alkaline overall water splitting

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Nano Research 2024年第5期17卷 3785-3793页

作者： Fangfang ren Jiayu Xu Ligang Feng College of Chemical and Environmental Engineering Yancheng Teachers UniversityYancheng 224007China School of Chemistry and Chemical Engineering Yangzhou UniversityYangzhou 225002China

The rational design of effective bifunctional electrocatalysts is of paramount importance for overall water-splitting technology in sustainable energy ***,bimetallic oxide catalysts(RuO_(2)-Co_(3)O_(4))derived from Ru combined MOF-derivatives(MOF=metal-organic framework)were demonstrated effective for overall water splitting in an alkaline solution,owing to the combined merits such as the two-dimensional interconnected network structure,the synergetic coupling effects and increased chemical *** as-prepared RuO_(2)-Co_(3)O_(4) only requires an overpotential of 260 mV for oxygen evolution and 75 mV for hydrogen evolution at 10 mA/cm^(2) in 1 M KOH solution;a low cell voltage of 1.54 V was required to reach the kinetic current density of 10 mA/cm^(2) for the water electrolysis when supporting on glass carbon electrode,and very good stability for 40 h was *** and theoretical results demonstrated the electronic structure optimization of bimetallic RuO_(2)-Co_(3)O_(4) compared to the individual metal oxide,which promoted interface charges redistribution and the d-band center downshift,resulting in increased activity and stability for water-splitting *** work provides a feasible approach for developing bimetallic oxides for application in energy-relevant electrocatalysis reactions.

关键词： ruthenium dioxide cobalt oxide metal-organic frameworks heterostructures overall water splitting

Supercoiled DNA Minicircles under Double-strand Breaks

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Chinese Journal of Polymer Science 2024年第9期42卷 1353-1359,I0007页

作者： Ye-Peng Qiao Chun-Lai ren National Laboratory of Solid State Microstructures and Department of Physics Collaborative Innovation Center of Advanced MicrostructuresNanjing UniversityNanjing210093China

Understanding how supercoiled DNA releases intramolecular stress is essential for its functional ***,the molecular mechanism underlying the relaxation process remains insufficiently *** we employed MD simulations based on the oxDNA2 model to investigate the relaxation process of a 336-base pair supercoiled minicircular DNA under double-strand breaks with two fixed *** simulations show that the conformational changes in the DNA occur continuously,with intramolecular stress release happening abruptly only when the DNA chain traverses the breakage *** relaxation process is influenced not only by the separation distance between the fixed ends but also their ***,we observe an inhibitory effect on the relaxation characterized by small angles,where short terminal loops impede DNA conformational adjustments,preserving the supercoiled *** findings elucidate the intricate interplay between DNA conformational change,DNA motion and intramolecular stress release,shedding light on the mechanisms governing the relaxation of supercoiled DNA at the molecular level.

关键词： Supercoiled DNA DNA minicircle DNA relaxation oxDNA model MD simulation

A blockchain-based data auditing scheme with key-exposure resistance for IIoT

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Science China(Information Sciences) 2024年第2期67卷 327-328页

作者： Pan YANG Jingli ren Henan Academy of Big Data Zhengzhou University

The Industrial Internet of Things(IIoT) enables enterprises to collect data from end devices and outsource the data to cloud servers for flexible data sharing. Public auditing plays an important role in ensuring the integrity of the *** are blockchain-based public auditing schemes that utilize smart contracts to achieve decentralized verification(such as [1]),

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Viscoelastic inorganic glass as solid-state electrolyte for batteries

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Journal of Materiomics 2024年第3期10卷 707-708页

作者： Yaoyu ren Ce-Wen Nan School of Materials Science and Engineering State Key Lab of New Ceramics and Fine ProcessingTsinghua UniversityBeijing100084China

A most recent exciting research result in the area of solid-state batteries that has been accepted for publication by the journal Nature Energy is *** research designed a new type of inorganic solid electrolyte named“viscoelastic inorganic glass(VIGLAS)”electrolyte with the compositions of LiAlCl_(2.5)O_(0.75)and NaAlCl_(2.5)O_(0.75).The newly developed solid electrolyte material showcases an excep-tional degree of deformability at room temperature,high ionic conductivity(>1 mS/cm at room tem-perature)and high oxidation stability(up to 4.3 V ***^(+)/Li or Na^(+)/Na).Using it as a catholyte enables a facile fabrication and a stable operation under practical stack pressure(<0.1 MPa)of all-solid-state *** represents a new path in the design of promising solid electrolytes for realizing high performance all-solid-state batteries.

关键词： Viscoelastic Inorganic glass Solid electrolyte Lithium battery Sodium battery

Envisioning Water-Resilient Cities Through the Lens of Blue-Green-Grey Solutions

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Engineering 2024年第5期36卷 1-2页

作者： Nan-Qi ren Glen Daigger School of Civil and Environmental Engineering Harbin Institute of Technology(Shenzhen)Shenzhen 518055China State Key Laboratory of Urban Water Resource and Environment Harbin Institute of TechnologyHarbin 150090China Department of Civil and Environmental Engineering University of MichiganAnn ArborMI 48109USA

Cities are dynamic systems,and the urban water systems within them can be evolved to provide water services to both humans and the environment while also enhancing the broader urban *** is done by embracing innovation and technological advancement while focusing on increased service to the human population and the local and broader *** the contemporary era,characterized by the rise of low-carbon and intelligent technologies,the swift pace of socioeconomic expansion highlights the critical need to address issues of urban water security and environmental *** escalating resource and environmental constraints,adopting holistic blue-green-grey strategies becomes imperative for the sustainable governance of urban water *** integrated approach is needed to navigate the intricate challenges of urban water dynamics while fostering enhanced ecological performance and resilience.

关键词： services urban advancement

Improved Simulation of Summer Heavy Rainfall over Beijing and Henan by the YHGSM with Updated Subgrid Orographic Parameters

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Journal of Meteorological Research 2024年第3期38卷 504-529页

作者： Yingjie WANG Jianping WU Kaijun ren College of Computer Science and Technology National University of Defense TechnologyChangsha410600China College of Meteorology and Oceanography National University of Defense TechnologyChangsha410600China

In numerical weather prediction(NWP),the parameterization of orographic drag plays an important role in representing subgrid orographic *** subgrid orographic parameters are the key input to the parameterization of orographic ***,the subgrid orographic parameters in most NWP models were produced based on elevation datasets generated many years ago,with a coarse resolution and low *** this paper,using the latest high-quality elevation data and considering the applicable scale range of the subgrid orographic parameters,we construct the orographic parameters,including the subgrid orographic standard deviation,anisotropy,orientation,and slope,that are required as input to the orographic gravity wave drag(OGWD)***,we introduce the newly constructed orographic parameters into the Yin-He Global Spectral Model(YHGSM),optimize the description of the orographic effect in the model,and improve the simulation of two typical heavy rainfall events in Beijing and Henan.

关键词： subgrid orographic parameters orographic drag heavy rainfall Yin-He Global Spectral Model(YHGSM) parameterization

On entire solutions of some Fermat type differential-difference equations

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Applied Mathematics(A Journal of Chinese Universities) 2024年第1期39卷 69-88页

作者： LONG Jian-ren QIN Da-zhuan School of Mathematical Sciences Guizhou Normal UniversityGuiyang 550025China

On one hand,we study the existence of transcendental entire solutions with finite order of the Fermat type difference *** the other hand,we also investigate the existence and growth of solutions of nonlinear different... 详细信息

关键词： entire solutions differential-difference equations existence finite order