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研制生态安全的固体火箭推进剂的可能途径

含能材料 1995年第2期3卷 9-19页

作者： Manilis G b(Institute of Chemical Physics in Cherogolovka,Russian Academy of Sciences)

本文叙述了常规火箭推进剂燃烧时产生大量污染环境，危及人类生存的有害物质，如一氧化碳和含氯化合物等致癌物。为研制生态安全的推进剂，如果不首先考虑推进剂的能量高、化学安定性和燃烧特性俱佳的氧化剂，企图进一步解决其它问题就... 详细信息

本文叙述了常规火箭推进剂燃烧时产生大量污染环境，危及人类生存的有害物质，如一氧化碳和含氯化合物等致癌物。为研制生态安全的推进剂，如果不首先考虑推进剂的能量高、化学安定性和燃烧特性俱佳的氧化剂，企图进一步解决其它问题就无意义。当然成本、工艺性和力学性能因素亦很重要。在探索研制配方时，可考虑选用硝酸铵、硝酸肼、二硝酰胺、硝仿肼等氧化剂取代ＮＨ＿４Ｃ１Ｏ＿４和ＨＭＸ。为此，本文着重介绍了由七种对化剂组成的配方并进行了热力学计算，结果表明以ＮＨ＿４Ｎ（ＮＯ＿２）：及Ｎ＿２Ｈ＿５Ｃ（ＮＯ＿２）３为基的配方的能量均高，而其燃烧室和喷管温度则分别低于以ＮＨ＿４Ｃ１Ｏ＿４和ＨＭＸ为氧化剂的推进剂燃烧产生的高温。就上述氧化剂热分解参数而言，在２０℃下，热分解０．１％所需时间，以Ｎａ－Ｃ１Ｏ＿４的为最长，以ＮＨ＿４Ｎ（ＮＯ＿２）＿２的为最短。其顺序为：Ｎ＿ａＣ１ｏ＿４＞ＮＨ＿４Ｎ）＿３＞β－ＨＭＸ＞Ｎ＿２Ｈ＿５ＮＯ＿３＞ＮＨ＿４Ｃ１Ｏ＿４＞Ｎ＿２Ｈ＿５Ｃ（ＮＯ＿２）：＞ＮＨ＿４Ｎ（ＮＯ＿２）＿２。文中对上述氧化剂的燃烧速率、压力指数和温度系数分别进行了实测和计算，除ＨＭＸ外，所得两值均较一致；还介绍了燃烧速率与氧化剂产物分解比?

关键词：火箭排出物环境污染固体推进剂热力学

Study of one-step and two-step neutron transfer in the reaction ^(6)Li+^(9)be

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Chinese Physics C 2024年第11期48卷 96-105页

作者： A.K.Azhibekov S.M.Lukyanov Yu.E.Penionzhkevich b.A.Urazbekov M.A.naumenko V.V.Samarin T.Issatayev V.A.Maslov K.Mendibayev D.Aznabayev T.K.Zholdybayev A.Temirzhanov Joint Institute for nuclear Research DubnaRussia Korkyt Ata Kyzylorda University KyzylordaKazakhstan national Research nuclear University MEPhI MoscowRussia L.n.Gumilyov Eurasian national University AstanaKazakhstan Dubna State University DubnaRussia Institute of nuclear Physics AlmatyKazakhstan Satbayev University AlmatyKazakhstan

This paper presents the results of experiments conducted to measure the cross-sections for elastic scattering and nucleon transfer channels in the ^(6)Li+^(9)be reaction at an incident energy of 68 MeV:^(9)be(^(6)Li,^(6)Li)^(9)be,^(9)be(^(6)Li,7Li)8be,^(9)be(^(6)Li,7Li)^(8)be_(2+),^(9)be(^(6)Li,^(8)Li)^(7)be,and ^(9)be(^(6)Li,^(7)be)^(8)*** objective of the study is to elucidate the manifestation of the cluster structure of ^(9)*** analysis of the contributions of the one-step and two-step neutron transfer mechanisms is performed using the distorted wave born approximation method with the Fresco *** agreement between the calculations and the experimental data is obtained for the channels of elastic scattering ^(9)be(^(6)Li,^(6)Li)^(9)be,neutron ^(9)be(^(6)Li,^(7)Li)^(8)be,and proton transfer ^(9)be(^(6)Li,^(7)be)^(8)Li,as well as for the transfer of two neutrons ^(9)be(^(6)Li,^(8)Li)^(7)*** dineutron cluster transfer mechanism makes a dominant contribution to the ^(9)be(^(6)Li,^(8)Li)^(7)be reaction channel at forward angles.

关键词： elastic scattering neutron and proton transfer reaction mechanisms DWbA Fresco code

Independent effects of diet and exercise training on fat oxidation in non-alcoholic fatty liver disease

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World Journal of Hepatology 2016年第27期8卷 1137-1148页

作者： Ilaria Croci nuala M byrne Veronique S Chachay Andrew P Hills Andrew D Clouston Trisha M O'Moore-Sullivan Johannes b Prins Graeme A Macdonald Ingrid J Hickman School of Human Movement and nutrition Sciences University of Queensland Translational Research Institute the University of Queensland Diamantina Institute b.n. Institute of Health and Sport Bond University Institute of Health and biomedical Innovation Queensland University of Technology School of Health Sciences University of Tasmania Mater Research Institute University of Queensland School of Medi-cine the University of Queensland Department of Gastroenterology and Hepatology Princess Alexandra Hospital Translational Research Institute Department of nutrition and Dietetics Princess Alexandra Hospital

AIM To investigate the independent effects of 6-mo of dietary energy restriction or exercise training on wholebody and hepatic fat oxidation of patients with nonalcoholic fatty liver disease(nAFLD).METHODS Participants were randomised into either circuit exercise training(EX;n = 13;3 h/wk without changes in dietary habits),or dietary energy restriction(ER) without changes in structured physical activity(ER;n = 8).Respiratory quotient(RQ) and whole-body fat oxidation rates(Fatox) were determined by indirect calorimetry under basal,insulin-stimulated and exercise *** of disease and steatosis was determined by liver histology;hepatic Fatox was estimated from plasma β-hydroxybutyrate ***;cardiorespiratory fitness was expressed as VO2 ***-case analysis was performed(EX:n = 10;ER:n = 6).RESULTS Hepatic steatosis and nAFLD activity score decreased with ER but not with EX.β-hydroxybutyrate concentrations increased significantly in response to ER(0.08 ± 0.02 mmol/L vs 0.12 ± 0.04 mmol/L,P = 0.03) but remained unchanged in response to EX(0.10 ± 0.03 mmol/L vs 0.11 ± 0.07 mmol/L,P = 0.39).basal RQ decreased(P = 0.05) in *** EX,while this change was not significant after ER(P = 0.38).VO_(2peak)(P nd maximal Fa_(tox) during aerobic exercise(P = 0.03) improved with EX but not with ER(P > 0.05).The increase in β-hydroxybutyrate concentrations was correlated with the reduction in hepatic steatosis(r =-0.56,P = 0.04).COnCLUSIOn ER and EX lead to specific b.n.fits on fat metabolism of patients with *** hepatic Fat_(ox) in response to ER could be one mechanism through which the ER group achieved reduction in steatosis.

关键词： non-alcoholic steatohepatitis Steatosis Fat and carbohydrate oxidation Exercise Fitness beta-hydroxybutyrate Ketone bodies Fatty acid oxidation

nonlinear optical characterization of single β-barium-borate nanocrystals using second-harmonic confocal microscopy

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Chinese Optics Letters 2018年第4期16卷 81-85页

作者： Rodrigo G.dos Santos Lauro J.Q.Maia Cid b.de Araújo Leonardo de S.Menezes Departamento de Fisica Universidade Federal de PernambucoRecife-PE 50670-901Brazil Instituto de Fisica Universidade Federal de CoiasCoiania-CO 74001-970Brazil

The confocal microscopy technique was applied for nonlinear optical characterization of single β-barium-borate（β-bbO） nanocrystals. The experimental setup allows measurements of the laser polarization-selective secondharmonic（SH） generation, and the results can be used to determine the nanocrystals＇ c-axis orientation, as well as to obtain information about their second-order susceptibility χ^（2）. The dependence of the SH signal on the laser polarization allowed the discrimination of individual particles from aggregates. The data were fitted using a model that takes into account the bbO properties and the experimental setup characteristics considering（i） the electrostatic approximation,（ii） the effects of the microscope objective used to focus the light on the sample in an epi-geometry configuration, and（iii） the symmetry of χ^（2） for the β-bbO nanocrystals. A signal at the third-harmonic frequency was also detected, but it was too weak to be studied in detail.

关键词： SH bbO HR barium-borate nanocrystals using second-harmonic confocal microscopy nonlinear optical characterization of single

HnCO与CX(X=F,Cl,br)自由基反应机理的密度泛函理论研究

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化学学报 2002年第11期60卷 1941-1945页

作者：刘朋军 b潘秀梅赵岷孙昊苏忠民王荣顺东北师范大学化学学院功能材料化学研究所

用量子化学密度泛函理论的b3LYP方法 ,在 6 31+G 水平上按bERnY能量梯度解析全参数优化了HnCO与CX (X =F ,Cl,br)反应势能面上各驻点的几何构型 ,通过振动频率分析确认了中间体和过渡态 ,内禀反应坐标(IRC)对反应物、中间体、过渡态和... 详细信息

用量子化学密度泛函理论的b3LYP方法 ,在 6 31+G 水平上按bERnY能量梯度解析全参数优化了HnCO与CX (X =F ,Cl,br)反应势能面上各驻点的几何构型 ,通过振动频率分析确认了中间体和过渡态 ,内禀反应坐标(IRC)对反应物、中间体、过渡态和产物的相关性予以证实 ,对各驻点进行了零点能校正 (ZPE) ,在此基础上计算了反应能垒 .研究结果表明 ,与HnCO和其它小分子自由基反应不同 ,HnCO与CX自由基反应首先发生分子间H原子迁移 ,随后n与CX的C(1)原子相互靠近成键并生成较稳定的中间体 ,再发生n—C(2 )键的断裂 ,完成n向C(1)上的迁移并进一步解离为产物 .反应按反应物→TS1→IM→TS2→产物通道进行 .反应为放热反应 .

关键词： HnCO CX 异氰酸碳卤自由基反应机理密度泛函理论量子化学

Sialyl Lewis X-dependent Lung Colonization of b16 Melanoma Cells Through a Selectin-like Endothelial Receptor Distinct from E- or P-Selectin

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Sialyl Lewis X-dependent Lung Colonization of B16 Melanoma C...

Review of pharmacologic and immunologic agents in the management of COVID-19

第八届全国复合糖生物化学与分子生物学学术会议

作者： Jun nakayama Chikara Ohyama Masami Suzuki Atsushi Suzuki Minoru Fukuda Michiko n.Fukuda DepartmentofUrology AkitaUniversitySchoolofMedicineAkita010-8543Japan GlycobiologyPrograln CancerResearchCenterTheBurnhamInstituteLaJolla、California92037.USA GlycobiologyProgram CancerResearchCenterTheBurnhamInstituteLaJolla、California92037.USA TheInstituteofOrgallTransplants ReconstructiveMedicineandTissueEngineeringShinshuUniversityGraduateSchoolofMedicineMatsumoto390-8621Japan

Endothelial carbohydrate b.n.ing proteins,E-and P-selectins,are thought to mediate sialyl Lewis A/X-dependent hematogenous cancer *** tested this hypothesis using sialyl Lewis X-dependen

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biosafety and Health 2021年第3期3卷 148-155页

作者： Marzuq A.Ungogo Mustapha Mohammed bala n.Umar Auwal A.bala Garba M.Khalid Department of Veterinary Pharmacology and Toxicology Ahmadu Bello UniversityZaria 810107Kaduna StateNigeria Institute of Infection Immunity and InflammationCollege of MedicalVeterinary and Life SciencesUniversity of GlasgowGlasgow G128TAUnited Kingdom School of Pharmaceutical Sciences Universiti Sains Malaysi1Penang City 11800Pulau Pinang StateMalaysia Department of Clinical Pharmacy and Pharmacy Practice Ahmadu Bello UniversityZaria 810107Kaduna StateNigeria Department of Veterinary Microbiology Faculty of Veterinary MedicineAhmadu Bello UniversityZaria 810107Kaduna StateNigeria Department of Pharmacology College of Medicine and Health SciencesFederal UniversityDutse 720231Jigawa StateNigeria Faculty of Pharmaceutical Sciences Bayero UniversityKano P.M.B.3011Kano StateNigeria Department of Pharmaceutical Sciences UniversitàDegli Studi di MilanoVia G.Colombo71Milano 20133Italy

The novel coronavirus disease 2019(COVID-19)is the third coronavirus outbreak in the last two *** and re-emerging infections like COVID-19 pose serious challenges of the paucity of information and lack of specific cure or *** leaves utilisation of existing scientific data on related viral infections and repurposing relevant aetiologic and supportive therapies as the best control approach while novel strategies are developed and *** promising antiviral agents including lopinavir,ritonavir,remdesivir,umifenovir,darunavir,and oseltamivir have been repurposed and are currently trialled for the care for COVID-19 *** therapies for the management of symptoms and to provide support especially in severe and critically ill patients have also been *** review provides an appraisal of the current evidence for the rational use of frontline therapeutics in the management of *** also includes updates regarding COVID-19 immunotherapy and vaccine development.

关键词： SAR-CoV-2 COVID-19 Respiratory Drug repurposing Antiviral Supportive therapy Immunotherapy

以腺病毒为载体的基因治疗对急性肺损伤治疗效果的影响及其意义

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中华医学杂志 2008年第26期88卷 1841-1845页

作者：王燕陆权滕国良 Feistein S. Sheldon Micheal F. beers Aron b. Fisher 上海交通大学附属儿童医院呼吸科 200040 上海交通大学附属儿童医院急救中心 200040 the Institute of Environmental Medicine the Center of Lung Biology University of Pennsylvania Philadelphia PA USA Department of Pulmonary andCritical Care Medicine University of Pennsylvania Philadelphia PA USA

目的评价腺病毒自身的致炎作用在以其为载体的基因治疗中，对小鼠急性肺损伤（ALI）治疗效果的影响及意义。方法C57／b6雄性小鼠随机分为4组：（1）以腺病毒为载体的靶基因LacZ治疗组（AdLacZ组）：43只；（2）3个对照组：①O2吸入前组... 详细信息

目的评价腺病毒自身的致炎作用在以其为载体的基因治疗中，对小鼠急性肺损伤（ALI）治疗效果的影响及意义。方法C57／b6雄性小鼠随机分为4组：（1）以腺病毒为载体的靶基因LacZ治疗组（AdLacZ组）：43只；（2）3个对照组：①O2吸入前组（Con组）：26只；②O2吸入后组：TbS＋磷酸盐缓冲液（PbS）治疗组（PbS组）36只；③无治疗对照组（无治疗组）：33只。100％O2吸入诱导小鼠高氧性ALI动物模型；在100％O2吸入前48h经鼻腔通道给予装载LacZ DnA的腺病毒质粒感染小鼠，并观察小鼠的死亡率。β-半乳糖酶活性测定法用于确定转染的LacZ基因在肺脏的蛋白活性的表达水平；肺的干／湿重比、支气管-肺泡灌洗液内的蛋白浓度和细胞分类分析用于评价肺炎症反应的程度。结果经鼻腔通路的以腺病毒为载体的基因治疗，可造成转染基因LacZ的蛋白表达活性在肺脏持续有效地高表达，而且其表达水平在O2吸入72h后仍可维持为O2吸入前的2倍以上（3．688U／mg vs 1．589U／mg）；该组小鼠对高氧吸入敏感性高于各对照组，50％的小鼠生存时间短于PbS组[（86±3）h vs （94±7）h]；同时，该组小鼠的支气管-肺泡内炎症细胞的渗出在100％O2吸入48h后明显高于各对照组，继续O2吸入24h后明显下降约50％；肺干／湿重比和支气管-肺泡灌洗液内蛋白浓度无明显下降。结论腺病毒自身的致炎作用对ALI基因治疗效果的影响是轻度和暂时的，但需在评价治疗效果时加以重视。

关键词：腺病毒科基因疗法呼吸窘迫综合征,成人

Families of Sordariomycetes

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Fungal Diversity 2016年第4期79卷 1-317页

作者： Sajeewa S.n.Maharachchikumbura Kevin D.Hyde E.b.Gareth Jones E.H.C.McKenzie Jayarama D.bhat Monika C.Dayarathne Shi-Ke Huang Chada norphanphoun Indunil C.Senanayake Rekhani H.Perera Qiu-Ju Shang Yuanpin Xiao Melvina J.D’souza Sinang Hongsanan Ruvishika S.Jayawardena Dinushani A.Daranagama Sirinapa Konta Ishani D.Goonasekara Wen-Ying Zhuang Rajesh Jeewon Alan J.L.Phillips Mohamed A.Abdel-Wahab Abdullah M.Al-Sadi Ali H.bahkali Saranyaphat boonmee nattawut boonyuen Ratchadawan Cheewangkoon Asha J.Dissanayake Jichuan Kang Qi-Rui Li Jian Kui Liu Xing Zhong Liu Zuo-Yi Liu JJennifer Luangsa-ard Ka-Lai Pang Rungtiwa Phookamsak Itthayakorn Promputtha Satinee Suetrong Marc Stadler Tingchi Wen nalin n.Wijayawardene Guizhou Key Laboratory of Agricultural biotechnology Guizhou Academy of Agricultural SciencesGuiyang 550006GuizhouChina Center of Excellence in Fungal Research and School of ScienceMae Fah Luang UniversityChiang Rai 57100Thailand Department of Crop Sciences College of Agricultural and Marine SciencesSultan Qaboos UniversityP.O.Box 34Al-Khod 123Oman Department of botany and Microbiology College of ScienceKing Saud UniversityP.O.Box 2455Riyadh 11451Kingdom of Saudi Arabia Manaaki Whenua Landcare Research Private Bag 92170AucklandNew Zealand no.128/1-J Azad Housing SocietyCurcaP.O.Goa Velha403108 GoaIndia Department of botany Goa UniversityGoa 403206India Engineering Research Center of Southwest bio-Pharmaceutical Resources Ministry of EducationGuizhou UniversityGuiyang 550025Guizhou ProvinceChina Institute of Plant and Environment Protection Beijing Academy of Agriculture and Forestry SciencesNo 9 of ShuGuangHuaYuanZhangLuHaidian District Beijing 100097China State Key Laboratory of Mycology Institute of MicrobiologyChinese Academy of SciencesBeijing 100101China Department of Health Sciences Faculty of ScienceUniversity of MauritiusReduitMauritius Faculty of Sciences Biosystems and Integrative Sciences Institute(BioISI)University of LisbonCampo Grande1749-016 LisbonPortugal Department of botany Faculty of ScienceSohag UniversitySohagEgypt Fungal biodiversity Laboratory BIOTECNational Science and Technology Development Agency(NSTDA)113 Thailand Science ParkThanon PhahonyothinTombon Khlong NuengAmphoe Khlong LuangPathum Thani 12120Thailand Department of Plant Pathology Faculty of AgricultureChiang Mai UniversityChiang Mai 50200Thailand Department of Pharmacy Guiyang Medical UniversityGuiyangGuizhou 550025China Microbe Interaction Laboratory BIOTECNational Science and Technology Development Agency(NSTDA)113 Thailand Science ParkThanon PhahonyothinTombon Khlong NuengAmphoe Khlong LuangPathum Thani 12120Thailand Institute of Marine biology and Center of Excell

Sordariomycetes is one of the largest classes of Ascomycota that comprises a highly diverse range of fungi characterized mainly by perithecial ascomata and inoperculate unitunicate *** class includes many important plant pathogens,as well as endophytes,saprobes,epiphytes,coprophilous and fungicolous,lichenized or lichenicolous *** occur in terrestrial,freshwater and marine habitats *** paper reviews the 107 families of the class Sordariomycetes and provides a modified backb.n. tree based on phylogenetic analysis of four comb.n.d loci,with a maximum five representative taxa from each family,where *** paper brings together for the first time,since barrs’1990 Prodromus,descriptions,notes on the history,and plates or illustrations of type or representative taxa of each family,a list of accepted genera,including asexual genera and a key to these taxa of *** of taxa is supported where possible by molecular *** outline is based on literature to the end of 2015 and the Sordariomycetes now comprises six subclasses,32 orders,105 families and 1331 *** family Obryzaceae and Pleurotremataceae are excluded from the class.

关键词： Amplistromatales Annulatascales boliniales Calosphaeriales Chaetosphaeriales Coniochaetales Conioscyphales Cordanales Coronophorales Diaporthales Falcocladiales Glomerellales Hypocreales Jobellisiales Koralionastetales Lulworthiales Magnaporthales Melanosporales Meliolales Microascales Ophiostomatales Phylogeny Phyllachorales Pisorisporiales Pleurotheciales Sordariales Savoryellales Tirisporellales Togniniales Torpedosporales Trichosphaeriales Taxonomy Trichosphaeriales Type species Xylariales