检索结果-南通市图书馆

UV Assisted Preliminary DNA Binding Studies and Single-crystal X-ray Structure of 4-{(4-Nitrophenyl-sulfonamido)methyl}cyclohexanecarboxylic Acid

引用

Chinese Journal of Structural Chemistry 2017年第5期36卷 745-750页

作者： MUHAMMAD Danish rabia ayub butt MUHAMMAD Nawaz Tahir MUHAMMAD Ashfaq SYEDA Tahira Hafeez Department of Chemistry University of GujratGujrat 50700Pakistan Department of Physics University of SargodhaSargodhaPakistan

A new sulfonamide, 4-{（4-nitrophenylsulfonamido）methyl}cyclohexanecarboxylic acid（C14H18N2O6S）, has been synthesized by the reaction of tranexamic acid and 4-nitrobenzenesulfonyl chloride in basic medium at room temperature. The molecular structure was determined by FT-IR, NMR, elemental analysis and single-crystal X-ray technique. X-ray diffraction shows that the compound crystallizes in the monoclinic system, space group P21/c with a = 13.5980（7）, b = 4.9877（2）, c = 23.3878（13） A, β = 93.254（3）°, Z = 4, V = 1583.67（14） A3, μ = 0.237 mm-1, F（000） = 720, R = 0.0471 and w R = 0.1182. The molecules are related by inversion and paired into dimers via C–H…O interactions. The dimmers are interlinked due to strong N–H…O bonds, where O-atoms are of sulfonyl groups. The molecules are stabilized in the form of infinite two-dimensional network with base vectors [0 1 0] and [0 0 –1] in the plane（1 0 2）. The existence of good intermolecular interactions suggests the biological importance of the synthesized molecule. The compound was screened for its interaction with FS-DNA using UV-visible spectroscopy. UV-visible spectroscopic results depict that the compound interacts with DNA by mixed binding mode intercalation along with hydrogen bonding. Negative values of ΔG（–23.34, –17.79 k J·mol-1） indicate spontaneity of the compound-DNA adduct formation.

关键词： sulfonamide tranexamic acid 4-nitrobenzenesulfonyl chloride XRD FS-DNA,intercalation

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Structure Elucidation and Biological Screening of Bis(4-{[(E)-(2-Hydroxybenzylidene)amino]methyl}-cyclohexane-carboxylato-O)-triaqua-cadmium

引用

Chinese Journal of Structural Chemistry 2018年第6期37卷 871-877页

作者： MUHAMMAD Danish SABA Akbar MUHAMMAD Nawaz Tahir MUHAMMAD Naeem Ahmed rabia ayub butt MUHAMMAD Asam Raza MUHAMMAD Ashfaq Department of Chemistry University of Gujrat Department of Physics University of Sargodha Department of Chemistry University of Azad Jammu and Kashmir

Using a bidentate ligand, a Schiff base 4-（{[（Z）-（2-hydroxyphenyl）methyldene]amino}methyl）cyclohexanecarboxylic acid, complex I（ML2, where M = Cd（Ⅱ）） was synthesized and characterized by IR spectroscopy and X-ray crystallography. It crystallizes in monoclinic system, space group C2/c, M_r = 685.04, 0.34 mm × 0.26 mm × 0.14 mm, a = 54.050（3）, b = 6.1220（3）, c = 9.5081（5） A, β = 90.229（2）°, Z = 4, C_（30） H_（40） CdN_2 O_9 and V = 3146.2（3） A^3. Complex I was screened for its bactericidal activity against four bacterial strains Chromohalobactersalexigens, Chromohalobacterisraelensis, Halomonashalofila and Halomonassalina and fungicidal activity against Aspergillusnigerand Aspergillusflavus. Antimicrobial activity results showed that the synthesized complex displayed good anti-fungal activity against two fungal strains. It was found to be inactive against four different bacterial strains analyzed and was negative for bactericidal effect.

关键词： Schiff base tranexamic acid Cd XRD fungicidal activity bactericidal activity

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

4-((4-Chlorophenylsulfonamido)methyl)cyclohexanecarboxylic Acid： Synthesis, Crystal Structure and Biological Activities

引用

Chinese Journal of Structural Chemistry 2017年第8期36卷 1307-1314页

作者： MUHAMMAD Danish rabia ayub butt MUHAMMAD Nawaz Tahir MUHAMMAD Ashfaq SYEDA Tahira Hafeez MUHAMMAD Naeem Ahmed HALEEMA Qureshi Department of Chemistry University of Gujrat Gujrat 50700 Pakistan Department of Physics University of Sargodha Sargodha Pakistan Department of Chemistry University of Azad Jammu and Kashmir Muzaffarabad 13100 Pakistan

In this study, a novel 4-（（4-chlorophenylsulfonamido）methyl）cyclohexanecarboxylic acid（C（14）H（18）ClNO4S） was synthesized by the reaction of tranexamic acid and 4-chlororbenzene sulfonyl chloride in basic medium at room temperature. The molecular structure was determined by FT-IR, NMR, elemental analysis and single-crystal X-ray analysis. The compound crystallizes in the monoclinic system, space group P21/c with a = 12.3120（11）, b = 16.5987（19）, c = 7.6873（7）？, β = 90.495（6）o, Z = 4 and V = 1570.9（3）？~3, crystal size（mm） = 0.38 × 0.16 × 0.14 and Rint = 0.045. In this compound, the carboxylic acid A（O（1）/C（1）/C（2）） and the sulfonyl B（O（3）/S（1）/O（4）） moieties are of course planar. The molecules are dimerized due to the O–H…O type of H-bonding with the R22（8） ring motifs. The dimmers are interlinked through C–H…O and N–H…O types of H-bonding. The synthesized compound was screened against four bacterial and two fungal strains and inactive against all strains. Antioxidant activity was checked against DPPH. Enzyme inhibition activity was carried out using three different enzymes and the title compound was more potent α-chymotrypsin inhibitor.

关键词： sulfonamide tranexamic acid 4-chlorobenzenesulfonyl chloride XRD biological applications

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Cogent and Energy Efficient Authentication Protocol for WSN in IoT

引用

Computers, Materials & Continua 2021年第8期68卷 1877-1898页

作者： Tariq Mahmood butt rabia Riaz Chinmay Chakraborty Sanam Shahla Rizvi Anand Paul Department of CS&IT University of Azad Jammu and KashmirMuzaffarabad13100Pakistan Birla Institute of Technology MesraJharkhand814142India Raptor Interactive(Pty)Ltd. Eco BoulevardWitch Hazel AveCenturion0157South Africa The School of Computer Science and Engineering Kyungpook National UniversityDaegu41566Korea

Given the accelerating development of Internet of things(IoT),a secure and robust authentication mechanism is urgently required as a critical architectural *** IoT has improved the quality of everyday life for numerous people in many *** to the predominantly wireless nature of the IoT,connected devices are more vulnerable to security threats compared to wired *** authentication is thus of utmost importance in terms of security on the *** authentication protocols have been proposed in recent years,but most prior schemes do not provide sufficient security for these wireless *** overcome the limitations of previous schemes,we propose an efficient and lightweight authentication scheme called the Cogent Biometric-Based Authentication Scheme(COBBAS).The proposed scheme is based on biometric data,and uses lightweight operations to enhance the efficiency of the network in terms of time,storage,and battery consumption.A formal security analysis of COBBAS using Burrows–Abadi–Needham logic proves that the proposed protocol provides secure mutual *** security verification using the Automated Validation of Internet Security Protocols and Applications tool shows that the proposed protocol is safe against man-in-the-middle and replay *** security analysis further shows that COBBAS protects wireless sensor networks against several security attacks such as password guessing,impersonation,stolen verifier attacks,denial-of-service attacks,and errors in biometric *** protocol also provides user anonymity,confidentiality,integrity,and biometric recovery in acceptable time with reasonable computational cost.

关键词： Internet of things wireless sensor networks authentication Burrows-Abadi-Needham logic fuzzy extractor elliptic curve cryptography

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Susceptibility of <i>Culex quinquefasciatus</i>(Diptera: Culicidae) to malathion in Sargodha district, Pakistan

引用

Open Journal of Animal Sciences 2013年第4期3卷 1-4页

作者： Hafiz Muhammad Tahir Kishwar Hussain Azhar Abbas Khan Sajida Naseem Hamza Tanveer Malik Abida butt rabia Yaqoob College of Medicine American University of Antigua New York USA Department of Agricultural Entomology University College of Agriculture University of Sargodha Sargodha Pakistan Department of Biological Sciences University of Sargodha Sargodha Pakistan Department of Biological Sciences University of Sargodha Sargodha Pakistan Department of Zoology University of Punjab Lahore Pakistan

The present study was designed to evaluate the susceptibility of Culex quinquefasciatuns against malathion in Sargodha district of Pakistan. The activities of detoxifying enzymes i.e., β-esterases, GSTs and monooxygenases were also estimated. Our results revealed 100 percent mortality in insecticide treated groups after 24 hours of exposure. There was no difference in the activities of insecticide detoxifying enzymes between control and treated groups. We concluded from our work that malathion is still effective against C. quinquefasciatuns in the area for control of mosquito population.

关键词： C. quinquefasciatuns Susceptibility Esterases Glutathione S-Transfereases Malathion

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：