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neurotransmitter systems in mouse airways

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中国药理学与毒理学杂志 2017年第10期31卷 1015-1016页

作者： Peter w ABEL Cameron M kieffer Ya-ping TU Department of Pharmacology Creighton University School of Medicine

OBJECTIVE The objective of this study was to characterize the neurotransmitter systems that cause constriction of murine *** Murine precision cut lung slices(PCLs)and trachea were prepared,placed into perfusion chambers equipped with platinum electrodes and stimulated transmurally(1.0 ms,50 V,0.1-30 Hz).To measure PCLs constriction,changes in airway luminal area in response to electric field stimulation(EFs)were captured as video images quantified using Image J *** trachea,changes in isometric tension were recorded using Grass force *** response curves were generated in the absence and the presence of the inhibitors magnesium,atropine and capsaicin and responses analyzed and compared using a student's t-test(PrEsULTs EFs caused airway constriction in a frequency-dependent manner that was best fit by a biphasic ***-specific stimulation was verified by Mg^(2+) *** airway constriction to 30 Hz EFs in PCLs was(51.8±3.0)%while tracheal constriction averaged(551±80)***,in PCLs the muscarinic receptor antagonist atropine(10μmol·L^(-1))blocked(99.5±7.2)%of EFs induced constriction at 1 Hz,but only blocked(23.3±3.8)%of EFs induced constriction at 30 Hz and eliminated the first phase but not the second phase of the biphasic EFs *** with capsaicin to deplete sensory neurotransmitters significantly increased EFs constriction supporting the presence of sensory neurotransmitter systems in *** These data are consistent with parasympathetic constriction of airways by acetylcholine at lower EFs frequencies while higher frequencies release sensory dilator *** data provide evidence for multiple nerve types innervating airways which may provide novel targets for treatment of lung disease.

关键词： airways nerve stimulation airway constriction atropine capsaicin

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XUV spectroscopy of subpicosecond Laser Produced Plasmas

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Chinese Physics Letters 1994年第9期11卷 554-557页

作者： JIAnG Zhiming J.C.kieffer M.Chaker On leave from shanghai Institute of Optics and Fine Mechanics Academia SinicaShanghai 201800 Institute national de la recherchèscientifique INRS-énergie et matérauxC.P.1020VarennesQuebecCanada J3X 1S2

The keV and XUV spectra of plasmas produced by the interaction of a laser pulse of various duration and wavelengths with,a solid Al target are compared and *** decrease of the XUV emission from the high ionization states was observed with the shortest pulses(500fs)and the shortest wavelength(0.5μm),which may be due to rapid cooling and quenching of ultrashort-lived and initially ultra-dense plasmas.

关键词： ultrashort shortest picosecond

Effects of plunge pool configuration on downstream passage survival of juvenile blueback herring

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Aquaculture and Fisheries 2021年第2期6卷 135-143页

作者： Theodore Castro-santos Kevin B.Mulligan Micah kieffer Alexander J.Haro u.s.geological survey-leetown science center s.o.conte anadromous fish research centerone migratory wayturners fallsma01376usa

Anadromous alosines are widespread throughout the northern *** of this clade are notoriously fragile animals that are at high risk of injury and death associated with passage at hydroelectric *** turbine mortality is a common concern,conditions encountered when bypassed around these routes may also be *** bypass structures typically discharge into plunge pools,which are highly turbulent and may cause mechanical *** subjected live,actively migrating juvenile blueback herring to a suite of realistic plunge pool conditions(3 m drop,pool depth of 60-180 cm,and discharge of 0.28-1.70 m^(3)/s)and monitored them for≥96 *** was generally higher than expected(>80%in all cases).However,both plunge pool volume and total discharge affected survival with elevated discharge and shallow conditions associated with increased *** was often delayed:rates remained elevated throughout the monitoring period,indicating that survival studies based on shorter periods underestimate total mortality.

关键词： Fish passage river herring Blueback herring Plunge pool survival

Three-Points Modulator Based on DPLL for wideband Polar Modulation

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Communications and network 2013年第3期5卷 140-143页

作者： Julien kieffer sé bastien rieubon Marc Houdebine sé bastien Dedieu Emil novakov IMEP-LAHC University of Grenoble-Alpes Grenoble France sT-Ericsson Grenoble France sTMicroelectronics Crolles France

we present a nonlinear event-driven model of a Digital PLL used in the context of a polar modulation. This modeling has shown that the estimation method of the TDC gain has a big impact on the EVM for wideband modulation and a solution has been proposed which consists to add the modulation on the gain after calibration of the gain offset. This transforms the classical two-points modulator into a three-points modulator. This implementation has been validated for wCDMA standard.

关键词： DPLL Polar Modulation wCDMA TDC

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提高垃圾填埋甲烷回收

提高垃圾填埋甲烷回收

Medium-term mortality after hip fractures and COVID-19:A prospective multicentre UK study

2007国际甲烷市场化大会暨展览会

作者：奥古司登 ramin Yazdani Jeff kieffer Paul Imhoff Morton Barlaz Harold Bentley John Benemann 环境管理学会(IEM有限公司) Yolo城市公共建设工程与规划特拉华州大学北卡罗来纳州立大学 Hydro Geo Chem公司

＜正＞最新评估,美国加利福尼亚大规模测试结果甲烷市场化展览会,中国北京。2007年10月30日-11月1日,由中国国家发展与改革委员会和美国环境保护署共同主办。美国版权属于IEM（有限）公司。按照Creative CommonsAttribution-share Alike...

＜正＞最新评估,美国加利福尼亚大规模测试结果甲烷市场化展览会,中国北京。2007年10月30日-11月1日,由中国国家发展与改革委员会和美国环境保护署共同主办。美国版权属于IEM（有限）公司。按照Creative CommonsAttribution-share Alike 3.0 United states License美利坚合众国规定,可以免费使用。请参见以下网址http://***/licenses/by-sa/3.0/us/

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Chinese Journal of Traumatology 2022年第3期25卷 161-165页

作者： Gareth Chan Ashish narang Arash Aframian Zaid Ali Joseph Bridgeman Alastair Carr Laura Chapman Henry Goodier Catrin Morgan Chang Park sarah sexton Kapil sugand Thomas walton Michael wilson Ajay Belgaumkar Kieran Gallagher Koushik Ghosh Charles Gibbons Joshua Jacob Andrew Keightley Zuhair nawaz Khaled sarraf Christopher wakeling william kieffer Benedict rogers Brighton&sussex University Hospitals nHs Trust Brighton&Sussex Medical SchoolFainter CampusBrighton UK surrey&sussex Healthcare nHs Trust Canada&venueRedhillUK Chelsea&westminster Hospital nHs Foundation Trust LondonUK Ashford&st frier's Hospital NHS Foundation TrustChertseyUK western sussex Hospitals nHs Foundation Trust(sr Richard's Hospital)ChichesterUK Poole General Hospital&the royal Bournemouth Hospital froleUK Imperial College Healthcare nHs Trust LondonUK western sussex Hospitals nHs Foundation Trust(worthing Hospital) WorthingUK royal surrey Hospital nHs Foundation Trust GuildfordUK Frimley Health nHs Foundation Trust FrimleyUK

Purpose:The COVID-19 pandemic has caused 1.4 million deaths globally and is associated with a 3-4 times increase in 30-day mortality after a fragility hip fracture with concurrent COVID-19 ***,death from COVID-19 infection occurs between 15 and 22 days after the onset of symptoms,but this period can extend up to 8 *** study aimed to assess the impact of concurrent COVID-19 infection on 120-day mortality after a fragility hip ***:A multi-centre prospective study across 10 hospitals treating 8%of the annual burden of hip fractures in England between 1st March and 30th April,2020 was *** whose surgical treatment was payable through the national Health service Best Practice Tariff mechanism for"fragility hip fractures"were included in the ***'120-day mortality was assessed relative to their perioperative COVID-19 *** analysis was performed using sPss version ***:A total of 746 patients were included in this study,of which 87(11.7%)were COVID-19 *** rates at 30-and 120-day were significantly higher for COVID-19 positive patients relative to COVID-19 negative patients(pwever,mortality rates between 31 and 120-day were not significantly different(p=0.107),16.1%and 9.4%respectively for COVID-19 positive and negative patients,odds ratio 1.855(95%CI 0.865-3.978).Conclusion:Hip fracture patients with concurrent COVID-19 infection,provided that they are alive at day-31 after injury,have no significant difference in 120-day *** the growing awareness and concern of "long-COVID"and its widespread prevalence,this does not appear to increase mediumterm mortality rates after a hip fracture.

关键词： Hip fractures Femoral fractures COVID-19 Coronavirus Mortality

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印度分盾细蜂总科新种记述(摘要)(英文)

昆虫分类学报 1983年第3期 219-224页

作者： s.K.sharma 印度动物调查所

本文记载3新种: Ceraphron siwalikus, sp. nov. 本种与古北区种类C. spinifer(kieffer)相近似,m脉与r脉之比相同,后背板有一刺,但不同处在于触角柄节长度与以下5节而不是4节之和相等,第2触角节的长度为厚度的3倍而不是2倍。本种亦与C. ... 详细信息

本文记载3新种: Ceraphron siwalikus, sp. nov. 本种与古北区种类C. spinifer(kieffer)相近似,m脉与r脉之比相同,后背板有一刺,但不同处在于触角柄节长度与以下5节而不是4节之和相等,第2触角节的长度为厚度的3倍而不是2倍。本种亦与C. alticola(kieffer)相近,但不同处为复眼不裸出而盖有稠密的毛,体形也较大。 Dendrocerus dalhousieanus, sp. nov. 本种与古北区种类D. fuscipennis(kieffer)相近似,不同处在于触角柄节基部不为淡黄色;翅在翅痣后方不为褐色。 Dendrocerus pykarus, sp. nov. 本种与D. indicus(Mani)不同处在于体长为2.10毫米,而后者为1.29毫米;触角第5索节不为圆柱形,而呈锯齿状;头部刻纹亦不相同。本种与暂时鉴定的D. fuscipes(kieffer)相近似,区别处在于仅只触角7～9节为圆柱形;翅痣位置稍微超过前缘的中部,离翅端不太近。

关键词： length view 触角柄节 body than