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睫状体厚度随轴性近视加重而增加

世界核心医学期刊文摘(眼科学分册) 2006年第3期 13-14页

作者： Oliveira C Tello C Liebmann J.M ritch r. 杨秀梅 New York Eye and Ear Infirmary 310 East 14th Street New York NY 10003 United StatesDr.

PUrPOSE: To assess the relationship between ciliary body thickness and refractive error. DESIGN: Prospective observational case series. METHODS: We enrolled 75 eyes of 75 patients with no history of intraocular surgery or use of anti-glaucoma medication. Axial length was measured by A-scan ultrasonography. Ciliary body thickness (CBT) was measured by two masked observers on radial-section images of the temporal corneoscleral limbus, acquired with ultrasound biomicroscopy (UBM) at 2 and 3 mm posterior to the scleral spur (CBT2 and CBT3, respectively). rESULTS: refractive error was inversely correlated with CBT2 and CBT3 (r=-0.64 and r=-0.52, Prespectively). Axial length was correlated with CBT (r=0.66 and r=0.57, Pr CBT2 and CBT3, respectively). CONCLUSION: CBT increases with increasing myopia and axial length.

关键词：睫状体葡萄膜厚度 CBT

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高度近视患者房角关闭

世界核心医学期刊文摘（眼科学分册） 2006年第6期2卷 48-49页

作者： Barkana Y. Shihadeh W. Oliveira C. r. ritch 安胜(译) 不详 Glaucoma Service Department of Ophthalmology New York Eye and Ear Infirmary 310 East 14th Street New York NY 10003 United States

Purpose: Patients with angle-closure glaucoma and high myopia are uncommon. We evaluated the clinical characteristics of all patients with angle closure and high myopia in our database and propose possible mechanisms for angle closure in these atypical patients. Design: retrospective noncomparative case series. Participants: Our database of 17938 patients was searched for patients with myopia of spherical equivalent of more than-6.0 diopters and angle closure. Data recorded included age at time of initial consultation,gender,slit-lamp examination results,gonioscopy results,biometric parameters,ultrasound biomicroscopy results (from 1993 onward),clinical diagnosis,and therapy. results: Twenty patients (11 females,9 males) were identified. Mean age at the time of consultation was 52.9± 19.3 years. Angle-closure diagnoses included primary pupillary block (9 patients),pupillary block in an eye with keratoconus (1 patient),pupillary block secondary to a pupillary membrane associated with retinopathy of prematurity (1 patient),plateau iris configuration and syndrome (3 patients),phacomorphic glaucoma in Weill-Marchesani syndrome (2 patients),malignant glaucoma secondary to a scleral buckle (2 patients),miotic-induced angle closure (1 patient),and Marfan syndrome (1 patient). Conclusions: Angle closure can occur in eyes with high myopia. Causes of angle closure other than relative pupillary block are more common than in the general angle-closure glaucoma population. Careful gonioscopy accompanied by biometry and ultrasound biomicroscopy can lead to the correct diagnosis and individualized management in these eyes.

关键词：近视患者房角关闭 Weill-Marchesani综合征超声生物显微镜检查闭角型青光眼早产儿视网膜病瞳孔阻滞临床诊断数据资料平均年龄

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手术治疗症状性、周围性结膜滤过泡

世界核心医学期刊文摘(眼科学分册) 2006年第12期 10-11页

作者： Anis S. ritch r. Shihadeh W. Liebmann J. 宋虎平 Glaucoma Service New York Eye and Ear Infirmary 310 E 14th St New York NY 10003 United StatesDr.

We describe methods and outcomes of surgical reduction of symptomatic, circumferential, filtering blebs after trabeculectomy with antifibrotic agents. The medical records of 15 eyes of 14 patients with symptomatic, circumferential blebs who underwent surgical bleb reduction for bleb dysesthesia under topical anesthesia were reviewed. Each bleb was incised segmentally and the cut edges of the conjunctiva and Tenon capsule were sutured to the underlying sclera. Outcome measures included symptomatic relief, retention of bleb function, and intraocular pressure maintenance. Fourteen eyes had successful reduction of bleb size, symptomatic relief, and cosmetically acceptable appearance. One eye continued to have dysesthesia and 1 had a transient bleb leak that resolved spontaneously. Surgical reduction of circumferential, symptomatic, filtering blebs is a safe and effective technique to reduce bleb dysesthesia and improve cosmesis without loss of bleb function.

关键词：结膜滤过泡症状性周围性手术治疗

正常眼压性青光眼与高眼压性青光眼视神经图像分析的对比研究

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中华眼底病杂志 2002年第2期18卷 109-112页

作者：窦宏亮 Pons Mauricio Mistlberger Andrea Ishikawa Hiroshi Liebmann Jeffrey ritch robert 第二炮兵总医院眼科北京100088 The New York Eye and Ear Infirmary

目的　探讨正常眼压性青光眼 (normal- tension glaucoma,NTG)与高眼压性青光眼 (high-tension glaucoma,HTG)视盘和视神经纤维层 (retinal nerve fiber layer,rNFL )损害的差异。　方法　选择具有青光眼性视神经损害或 rNFL 缺损、相... 详细信息

目的　探讨正常眼压性青光眼 (normal- tension glaucoma,NTG)与高眼压性青光眼 (high-tension glaucoma,HTG)视盘和视神经纤维层 (retinal nerve fiber layer,rNFL )损害的差异。　方法　选择具有青光眼性视神经损害或 rNFL 缺损、相应的视野缺损的青光眼患者 ,NTG至少 2次 2 4 h眼压曲线和多次眼压测量均≤ 2 1mm Hg(1mm Hg=0 .133k Pa) ,HTG的眼压至少 2次测量≥ 2 5 mm Hg。患者进行详细的眼科检查 ,同时用扫描激光偏振仪 (scanning laser polarimetry,SL P)、光学相干断层扫描 (opticalcoherence tomography,OCT)和海德堡视网膜成像仪 (Heidelberg retinal tomography,HrT)定量测定视盘形态和 rNFL厚度。比较两组视盘总体和相同象限测量参数。　结果　 30例 NTG和 19例 HTG (共 4 9只眼 )患者的平均年龄分别为 (5 9.6± 8.6 )岁 (39～ 71岁 )和 (5 9.2± 12 .3)岁 (36～ 75岁 )。两组间视野缺损的平均偏差 (mean deviation,MD)差异不显著 (P>0 .0 5 )。HrT测量的视盘 C/ D面积比 ,除鼻侧象限外 ,NTG者视盘总体和上、下、颞侧 3个象限均显著大于 HTG者 (PrNFL厚度。

关键词：正常眼压性青光眼高眼压性青光眼视神经图像视神经损伤病理生理学视盘损害对比分析 NTG HTG

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一项比较电生理学，心理生理学和青光眼损害结构测量的方法

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美国医学会眼科杂志（中文版） 2005年第2期17卷 125-126页

作者： Vivienne C. Greenstein Phamornsak Thienprasiddhi robert ritch Jeffrey M. Liebmann Donald C. Hood 齐越（译）

目的：开发一种比较将多焦视觉激发电位（mfVEP）反应和用行为判定视野以及视神经乳头结构的方法。

关键词：心理生理学电生理学结构眼损害测量青光视觉激发电位视神经乳头

一种比较青光眼电生理检查、心理物理学检查及形态学检查的方法

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世界核心医学期刊文摘（眼科学分册） 2005年第2期1卷 16-16页

作者： Greenstein V.C. Thienprasiddhi P. ritch r. 张磊 Departm ent of Ophthalmology New York Univ. School of Medicine 550 First Ave New York NY 10016 United States Dr.

Objective: To develop a method for comparing multifocal visual-evoked potenti al (mfVEP) responses and behaviorally determined visual fields with structural m easures of the optic nerve head. Methods: Humphrey 24-2 visual fields and mfVEP s were obtained from each eye of 20 patients with open angle glaucoma. Monocular and interocular analyses were performed to identify locations with abnormal mfV EP responses. Optic discs were assessed with a confocal scanning laser ophthalmo scope (Heidelberg retina Tomograph II). The image of the optic nerve head was di vided into 6 sectors. The rim and disc area measurements for each sector were co mpared with those in a normal database using Moorfields regression analysis. The optic nerve head measurements for the 6 sectors were related to the Humphrey vi sual field locations and the 60 sectors of the mfVEP display. results: Of 240 se ctors tested (40 eyes×6 sectors), 18.8%on Humphrey visual field, 22.1%on mfVE P, and 10.8%on confocal scanning laser ophthalmoscopic testing were significant ly different from those of control subjects. There were no significant deficits in 165 sectors. There was agreement for 86.7%of the sectors when the Humphrey v isual field and mfVEP results were compared. The confocal scanning laser ophthal moscopic results were in agreement for 84.6%of these sectors. Conclusions: The method used allows for a comparison among measures of visual function and a stru ctural measure of the optic nerve head. In general, the results of the functiona l and structural measures showed agreement;however, there were clear examples of disagreements that merit further study.

关键词：电生理检查心理物理学形态学检查视野检查视功能结构测量体层摄影有显著性差异测量结果

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