检索结果-南通市图书馆

Pro12Ala polymorphism of the peroxisome proliferator-activated receptor γ2 in patients with fatty liver diseases

World Journal of Gastroenterology 2010年第46期16卷 5830-5837页

作者： Johannes W rey Andrea Noetel Aline Hardt Ali Canbay Hakan Alakus Axel zur Hausen Hans Peter Dienes Uta Drebber Margarete Odenthal Institute for Pathology University Hospital of Freiburg Department of Gastroenterology and Hepatology University Hospital of Essen Department of General Visceral and Cancer SurgeryUniversity Hospital of Cologne

AIM:To test the occurrence of the Pro12Ala mutation of the peroxisome proliferator-activated receptor-γ (PPArγ)2-gene in patients with non-alcoholic fatty liver disease (NAFLD) or alcoholic fatty liver disease (AFLD).METHODS:DNA from a total of 622 specimens including 259 blood samples of healthy blood donors and 363 histologically categorized liver biopsies of patients with NAFLD (n=263) and AFLD (n=100) were analyzed by real-time polymerase chain reaction using allele-specific ***:In the NAFLD and the AFLD collective,3% of the patients showed homozygous occurrence of the Ala12 PPArγ2-allele,differing from only 1.5% cases in the healthy *** NAFLD patients,a high incidence of the Ala12 mutant was not associated with the progression of fatty liver ***,we observed a significantly higher risk (odds ratio=2.50,CI:1.05-5.90,P=0.028) in AFLD patients carrying the mutated Ala12 allele to develop inflammatory *** linkage of the malfunctioning Ala12-positive PPArγ2 isoform to an increased risk in patients with AFLD to develop severe steatohepatitis and fibrosis indicates a more prominent anti-inflammatory impact of PPArγ2 in progression of AFLD than of ***:In AFLD patients,the Pro12Ala single nuclear polymorphism should be studied more extensively in order to serve as a novel candidate in biomarker screening for improved prognosis.

关键词： Single nucleotide polymorphism Peroxisome proliferator-activated receptor γ Non-alcoholic steatohepatitis Alcoholic steatohepatitis Inflammation Fibrosis Hepatitis Steatosis Steatohepatitis

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Enhancing survival, engraftment, and osteogenic potential of mesenchymal stem cells

引用

World Journal of Stem Cells 2019年第10期11卷 748-763页

作者： Daniel García-Sánchez Darío Fernández JoséC rodríguez-rey Flor M Pérez-Campo Department of Molecular Biology Faculty of MedicineUniversity of CantabriaCantabria 39011Spain Laboratorio de Biología Celular y Molecular Facultad de OdontologíaUniversidad Nacional del NordesteCorrientes W3400Argentina Consejo Nacional de Investigaciones científicas y Técnicas Ciudad de CorrientesCorrientes W3400Argentina

Mesenchymal stem cells(MSCs)are promising candidates for bone regeneration therapies due to their plasticity and easiness of ***-based treatments are generally considered a safe procedure,however,the long-term results obtained up to now are far from *** main causes of these therapeutic limitations are inefficient homing,engraftment,and osteogenic *** studies have proposed modifications to improve MSC engraftment and osteogenic differentiation of the transplanted *** strategies are aimed to improve cell resistance to the hostile microenvironment found in the recipient tissue and increase cell survival after *** strategies could range from a simple modification of the culture conditions,known as cell-preconditioning,to the genetic modification of the cells to avoid cellular *** efforts have also been done in order to enhance the osteogenic potential of the transplanted cells and induce bone formation,mainly by the use of bioactive or biomimetic scaffolds,although alternative approaches will also be *** review aims to summarize several of the most recent approaches,providing an up-to-date view of the main developments in MSCbased regenerative techniques.

关键词： Mesenchymal stem cells Bone regeneration Hypoxia Anoikis Preconditioning Bioactive scaffolds Senescence Engraftment Homing Osteogenesis

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

reference penile size measurement and correlation with other anthropometric dimensions:a prospective study in 800 men

引用

Asian Journal of Andrology 2022年第6期24卷 620-623页

作者： Martina Sole Ignacio Tobia Gonzalezi Martin Compagnucci Guadalupe Colucci Marcos Dalvit Bernardo Chiconi Omar A Layus Guillermo Gueglio Gaston rey-Valzacchi Department of Urology at Hospital Italiano Buenos Aires C1199ABBArgentina Department of Urology at Sanatorio Allende Cordoba 5000Argentina Department of Urology at Hospital Privado de la Comunidad Mar del Plata 7600Argentina Department of Urology at Hospital Central Mendoza 5500Argentina

Virility and sexual pleasure have long been associated with penile size and this,in turn,has typically been linked to some anthropometric measurements,such as foot size or height,leading to various misconceptions from both men and *** intention is to estimate penile size parameters in Argentina and evaluate the correlation between penile size and certain anthropometric *** is a cross-sectional,descriptive,multicenter,and observational *** patients who underwent a urological procedure were included in four hospitals located in different regions of the *** anthropometric measurements were obtained:height,weight,penile circumference,flaccid and stretched length,and foot length.A total of 8o0 patients were *** left foot was 26.4 *** flaccid penile length was 11.4(95%confidence interval[CI]:8-14)cm,and mean penile circumference was 10.1(95%CI:8-12)***,mean stretched penis was 15.2(95%CI:11-18.5)*** can confirm that estimates of the average penile measurements in Argentina are flaccid penis length of 11.4 cm,penile circumference of 10.1 cm,and stretching the penis to the maximum in flaccidity of 15.2 *** between flaccid penis length,stretched out,penile circumference,height,weight,and length of the left foot were evaluated,finding low or no correlation between those mentioned,exceptforflaccidand stretched length.

关键词： anthropometric measurements micropenis penile percentile

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Evaporation and CO_(2)fluxes in a coastal reef:an eddy covariance approach

引用

Ecosystem Health and Sustainability 2017年第10期3卷 1-21页

作者： A.Camilo rey-Sánchez Gil Bohrer Timothy H.Morin Dekel Shlomo Golnazalsadat Mirfenderesgi Hezi Gildor Amatzia Genin Department of Civil Environmental and Geodetic EngineeringThe Ohio State UniversityColumbusOHUSA Department of Environmental resources Engineering State University of New York College of Environmental Science and ForestrySyracuseNYUSA The Fredy&Nadine Herrmann Institute of Earth Sciences the Hebrew University of JerusalemJerusalemIsrael The Interuniversity Institute for Marine Sciences of Eilat Coral BeachEilatIsrael department ofDepartment of Ecology Evolution&BehaviorSilverman Institute of Life Sciencesthe Hebrew University of JerusalemEilatIsrael ecologyevolution&behaviorsilverman institute of life sciencesthe hebrew university of jerusalemeilatisrael

Introduction:We conducted season-long observations of evaporation and carbon flux at the Gulf of Aqaba coast,northern red *** used the eddy-covariance method with a two-tower setup to measure evaporation rates over land and sea and the advection between *** a three-dimensional mass balance approach,we calculated total evaporation as the sum of two main components in our site:horizontal advection and turbulent vertical flux,with half-hourly change of water vapor storage and horizontal flux divergence found to be ***:Average evaporation rates were 11.4[mm/day]from April through May(early summer)and 10.5[mm/day]from June through August(summer).The coastal reef was a CO_(2)sink over the period of measurements,significantly higher in June through August than in April through *** main environmental drivers of CO_(2)flux were humidity,water temperature,sensible heat flux,and wind ***:The rates of evaporation near the shore were considerably higher than values reported in other studies typically used to represent the mean for the whole Gulf *** found that evaporation rates computed by common bulk models approximate the mean values of evaporation but have poor representativeness of the intra-daily temporal variation of *** was a significant correlation between CO_(2)flux and evaporation attributed to common environmental drivers of gas diffusion,turbulent fluxes,and horizontal ***:We conclude that observations of fluxes in coastal waters need to use at least a two-tower system to account for the effect of horizontal advection on the total flux.

关键词： Evaporation coral reef carbon flux advection eddy covariance

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

‘reversing’ the Flow of the Ancient Chinese Calendrical Subseasonal Phases Jie Qi in Australia:The Construction of a Chinese Medical & Agricultural Lunisolar Calendar(Northern and Southern Hemispheres)(Continued Part 2)

引用

山西中医学院学报 2008年第1期9卷 2-5页

作者： rey Tiquia Department of History & Philosophy of Science University of MelbourneAustralia

1 The Cyclical Flow of the Sixty-Gan zhi Temporal Units 'Time for the Chinese is forever flowing without beginning or end',noted Thome H. Fang. And'it is customary for Chinese to use the kan-Chih(gan zhi)to mark the passage of *** are ten heavenly stems(gan)and twelve earthly branches(zhi),an alternating and sequential combination of the two makes a cycle of sixty years,months,days and two-hour period shi chen(时辰)in a day'. The sixty gan zhi temporal cycle is very important in the practice of Chinese *** is an important practical temporal tool in the acupuncture practice of 子午流注(zi wu liu zhu)which is a method of choosing and using acupuncture points in dealing with a specific clinical pattern in accordance with the patient's temporal clotting and flowing of his/her Qi and *** addition,the sixty gan-zhi temporal cyclical system is also an important tool in forecasting adverse weather/climactic conditions and the illnesses that comes with them on the basis of the ancient methodology of 'the circulating five elements/phases and the six climactic influences'五运六气.Hence,I have included this gan zhi or celestial stems and earthly branches for each of the days in the Chinese Medical and Agricultural Lunisolar Calendar for the year of rat wu zi nian(wu is the celestial stem while zi is the earthly branch for the year 2008).

关键词：中国传统中医药医疗卫生事业澳大利亚

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

A Joint Optimization Algorithm for renewable Energy System

引用

Intelligent Automation & Soft Computing 2023年第5期36卷 1979-1989页

作者： Imran Khan Firdaus Muhammad-Sukki Jorge Alfredo Ardila rey Abdullahi Abubakar Mas’ud Saud Jazaa Alshammari DagØivind Madsen Department of Electrical Engineering University of Engineering and TechnologyPeshawar814Pakistan School of Engineering&the Built Environment Edinburgh Napier UniversityMerchiston Campus10 Colinton RoadEdinburghEH105DTScotlandUK Department of Electrical Engineering Federico Santa María Technical UniversitySantiago8940000Chile Department of Electrical and Electronics Engineering Jubail Industrial CollegeP O Box 10099Jubail 31961Saudi Arabia University of South-Eastern Norway Bredalsveien143511HønefossNorway

Energy sustainability is a hot topic in both scientiﬁc and political *** date,two alternative approaches to this issue are being *** peo-ple believe that increasing power consumption is necessary for countries’economic and social progress,while others are more concerned with maintaining carbon consumption under set *** establish a secure,sustainable,and economical energy system while mitigating the consequences of climate change,most governments are currently pushing renewable growth *** mar-kets are meant to provide consumers with dependable electricity at the lowest pos-sible cost.A proﬁt-maximization optimal decision model is created in the electric power market with the combined wind,solar units,loads,and energy storage sys-tems,based on the bidding mechanism in the electricity market and operational *** model utterly considers the technological limits of new energy units and storages,as well as the involvement of new energy and electric vehicles in market bidding through power generation strategy and the output arrangement of the virtual power plant’s coordinated *** accuracy and validity of the optimal decision-making model of combined wind,solar units,loads,and energy storage systems are validated using numerical *** multi-operating scenarios,the effects of renewable energy output changes on joint sys-tem bidding techniques are compared.

关键词： renewable energy optimizationalgorithm electricity market decision-making

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Moving With Times

引用

ChinAfrica 2020年第6期12卷 20-21页

作者： Geo rey Kamadi 不详

Kenyan enterprises explore new business opportunities to mitigate the impact of the pandemic The COVID-19 global pandemic continues to wreak havoc around the world in terms of human health,lives and *** is no *** country is estimated to have already lost 30,000 formal jobs,with another 140,000 becoming susceptible to the pandemic,according to Sachen Gudka.

关键词： enterprises Times becoming

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Clinical,radiological and molecular diagnosis correlation in serum samples from patients with osteoarticular tuberculosis

引用

Asian Pacific Journal of Tropical Biomedicine 2014年第7期4卷 581-585页

作者： Guadalupe Garcia-Elorriaga Olga Martinez-Elizondo Guillermo del rey-Pineda Cesar Gonzalez-Bonilla Unidad de Investigacion Medica en Inmunologia e Infectologia Hospital de InfectologiaCentro Medico Nacional La Raza(CMNR).Instituto Mexicano del Seguro Social(IMSS)Mexico City.Mexico(Medical Research Unit in Immunology and Infectious DiseaseHospital for Infectious Disease"La Raza"National Medical Center(CMNR).Mexican Social Security Institute(IMSS)Mexico CityMexico) Hospital de Ortopedia "Dr.Victorio de la Fuente Narvaez" Instituto Mexicano del Seguro Social(IMSS)Mexico CityMexico(Orthopedics Hospital " Dr.Victorio de la Fuente Narvaez"Mexican Social Security Institute(IMSS)Mexico CityMexico) Banco Central de Sangre CMNRIMSSand Departamento de InfectologiaHospital Infantil de Mexico Federico Gomez.Secretaria de Salud(SSA)Mexico CityMexico(Central Blood BankCMNR.IMSS and Department of Infectious Disease "Federico Comez" Children's Hospital.Health Ministry (SSA)Mexico CityMexico)

Objective:To assess the role of polymerase chain reaction(PCr)in serum sauples,in the diagnosis of osteoarticular tuberculosis(OTB)in a setting where only clinical and imaging diagnoses determine the ***:A total of 44 consecutive serum specimens were collected from clinically suspected OTB patients,based on clinical and radiological[X-ray or magnetic resonance imagng/computecl tomography]*** were scrcened by in-house nested *** addition,a few specimens were examined by Gram stain,acid-fast bacilli stain,histand routine bacterial culture.A total of 39 specimens were collected from patients suffering from other bone diseases of nontuberculous origin and included as negative ***:of the 44 clinically suspected OTB patients,in-house nested PCr was positive in 40(91%)cases;PCr was negative in 38(97%)negative *** and specificity of our in—house nested PCr was 90.3%and 97.4%,*** PCr report was available within 48 *** was possible to standardize serum PCr technique and in positive cases,a good n was observed in terms of an adequate treatment ***:Nested PCr in serum samples is a rapid,highly sensitive and specific modality for OTB detection,PCr should be performed in addition to clinical evaluation,imaging studies,acidfast bacilli staining,culture and histopathology diagnosis,if possible.

关键词： Osteoarticular tuberculosis Molecular diagnosis Nested polymerase chain reaction Sensitivity Specificity

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

The Prevalence and Surgical repair of Canine Medial Patellar Luxation in Southern Taiwan

引用

畜牧与兽医 2012年第S2期44卷 59-60页

作者： Chi-Hsien Chien rey-Shyong Chen Pei-Chun Chiu Chih-Chang Peng College of Veterinary Medicine Small Animal Surgery and AcupunctureAnimal Hospital National Pingtung University of Science and Technology

Medial patella luxation(MPL)is most common orthopedic disease in toy and miniature *** breed predisposition in the United States has been reported for the Boston Terrier,Chihuahua,Pomeranian,Miniature Poodle,and Yorkshire Terrier[1].In Japan,beside Pomeranian and toy poodle,the Japanese Chin and Shiba are mostly affected breeds[2].Multiple surgical techniques have been applied successfully to correct such disorders including

关键词： medial Japanese miniature breed correct mostly Taiwan Boston bilateral groove

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Advantages of early cholecystectomy in clinical practice of a terciary care center

引用

Hepatobiliary & Pancreatic Diseases International 2013年第1期12卷 87-93页

作者： Marta Barceló Dulce María Cruz-Santamaría Cristina Alba-López María José Devesa-Medina Manuel Díaz-rubio Enrique rey Health research Institute San Carlos Clinical HospitalDepartment of MedicineSchool of MedicineComplutense University

BACKGrOUND:Despite a number of studies show the superiority of early over delayed cholecystectomy in the treatment of acute cholecystitis,there is still controversy over the time for *** study aimed to assess the use of early versus delayed cholecystectomy for the treatment of acute cholecystitis in terms of complications,conversion to open surgery and mean hospital ***:We collected patients with acute cholecystitis treated at a referral center for a year,and retrospectively analyzed the chosen therapeutic approach,the percentage of conversion of early cholecystectomy to open surgery,appearance of surgical complications,and mean hospital ***:The study included 117 patients,44 women and 73 men,who had a mean age of 67.36±15.74 *** cholecystectomy was chosen in 31(26.5%) and delayed cholecystectomy in 74 patients(63.2%).Of the 74 patients,28(37.8%) required emergency performance of delayed cholecystectomy,and 19(25.7%) had not undergone surgery by the end of the *** no differences were observed between early and delayed cholecystectomy in terms of surgical complications and conversion to open surgery,mean hospital stay was nevertheless significantly shorter in the early versus the delayed cholecystectomy group(8.32±4.98 vs 15.96±8.89 days).CONCLUSION:Under the routine working conditions of a hospital that is neither specially dedicated to the surgical treatment of acute cholecystitis nor provided with specific management guidelines,early cholecystectomy can reduce the hospital stay without increase of the conversion rate or complications.

关键词： acute cholecystitis cholecystectomy complications

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：