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Search for the doubly charmed baryon ■

Science China(Physics,Mechanics & Astronomy) 2020年第2期63卷 8-22页

作者： r.Aaij C.Abellán Beteta T.Ackernley B.Adeva M.Adinolfi H.Afsharnia C.A.Aidala S.Aiola Z.Ajaltouni S.Akar P.Albicocco J.Albrecht F.Alessio M.Alexander A.Alfonso Albero G.Alkhazov P.Alvarez Cartelle A.A.Alves jr S.Amato Y.Amhis L.An L.Anderlini G.Andreassi M.Andreotti F.Archilli J.Arnau romeu A.Artamonov M.Artuso K.Arzymatov E.Aslanides M.Atzeni B.Audurier S.Bachmann J.J.Back S.Baker V.Balagura W.Baldini A.Baranov r.J.Barlow S.Barsuk W.Barter M.Bartolini F.Baryshnikov G.Bassi V.Batozskaya B.Batsukh A.Battig V.Battista A.Bay M.Becker F.Bedeschi I.Bediaga A.Beiter L.J.Bel V.Belavin S.Belin n.Beliy V.Bellee K.Belous I.Belyaev G.Bencivenni E.Ben-Haim S.Benson S.Beranek A.Berezhnoy *** D.Berninghoff H.C.Bernstein E.Bertholet A.Bertolin C.Betancourt F.Betti M.O.Bettler Ia.Bezshyiko S.Bhasin J.Bhom M.S.Bieker S.Bifani P.Billoir A.Birnkraut A.Bizzeti M.Bjφrn M.P.Blago T.Blake F.Blanc S.Blusk D.Bobulska V.Bocci O.Boente Garcia T.Boettcher A.Boldyrev A.Bondar n.Bondar S.Borghi M.Borisyak M.Borsato J.T.Borsuk T.J.V.Bowcock C.Bozzi S.Braun A.Brea rodriguez M.Brodski J.Brodzicka A.Brossa Gonzalo D.Brundu E.Buchanan A.Buonaura C.Burr A.Bursche J.S.Butter J.Buytaert W.Byczynski S.Cadeddu H.Cai r.Calabrese S.Cali r.Calladine M.Calvi M.Calvo Gomez A.Camboni P.Campana D.H.Campora Perez L.Capriotti A.Carbone G.Carboni r.Cardinale A.Cardini P.Carniti K.Carvalho Akiba A.Casais Vidal G.Casse M.Cattaneo G.Cavallero r.Cenci J.Cerasoli M.G.Chapman M.Charles Ph.Charpentier G.Chatzikonstantinidis M.Chefdeville V.Chekalina C.Chen S.Chen A.Chernov S.-G.Chitic V.Chobanova M.Chrzaszcz A.Chubykin P.Ciambrone M.F.Cicala X.Cid Vidal G.Ciezarek F.Cindolo P.E.L.Clarke M.Clemencic H.V.Cliff J.Closier J.L.Cobbledick V.Coco J.A.B.Coelho J.Cogan E.Cogneras L.Cojocariu P.Collins T.Colombo A.Comerma-Montells A.Contu n.Cooke G.Coombs S.Coquereau G.Corti C.M.Costa Sobral B.Couturier D.C.Craik J.Crkovska A.Crocombe M.Cruz Torres r.Currie C.L.Da Silva E.Dall'Occo J.Dalseno C.D'Ambrosio A.Danilina P.d'Argent A.Davis O.De Aguiar Francisco K.De Bruyn S.De Capua M Centro Brasileiro de Pesquisas Fisicas(CBPF) Rio de JaneiroBrazil Universidade Federal do rio de Janeiro(UFrJ) Rio de JaneiroBrazil Center for High Energy Physics Tsinghua UniversityBeijingChina School of Physics State Key Laboratory of nuclear Physics and Technology Peking UniversityBeijingChina University of Chinese Academy of Sciences BeijingChina Institute Of High Energy Physics(IHEP) BeijingChina Institute of Particle Physics Central China Normal UniversityWuhanHubeiChina Univ.Grenoble Alpes Univ.Savoie Mont BlancCNRSIN2P3-LAPPAnnecyFrance Universite Clermont Auvergne CNRS/IN2P3LPCClermont-FerrandFrance Aix Marseille Univ CNRS/IN2P3CPPMMarseilleFrance LAL Univ.Paris-SudCNRS/IN2P3Universite Paris-SaclayOrsayFrance LPnHE Sorbonne Universite Paris Diderot Sorbonne Paris Cite CNRS/IN2P3ParisFrance I.Physikalisches Institut RWTH Aachen UniversityAachenGermany Fakultat Physik Technische Universitat DortmundDortmundGermany Max-Planck-Institut für Kernphysik(MPIK) HeidelbergGermany Physikalisches Institut Ruprecht-Karls-Universitat HeidelbergHeidelbergGermany School of Physics University College DublinDublinIreland InFn Sezione di Bari BariItaly InFn Sezione di Bologna BolognaItaly InFn Sezione di Ferrara FerraraItaly InFn Sezione di Firenze FirenzeItaly InFn Laboratori nazionali di Frascati FrascatiItaly InFn Sezione di Genova GenovaItaly InFn Sezione di Milano-Bicocca MilanoItaly InFn Sezione di Milano MilanoItaly InFn Sezione di Cagliari MonserratoItaly InFn Sezione di Padova PadovaItaly InFn Sezione di Pisa PisaItaly InFn Sezione di roma Tor Vergata RomaItaly InFn Sezione di roma La Sapienza RomaItaly nikhef national Institute for Subatomic Physics AmsterdamNetherlands nikhef national Institute for Subatomic Physics and VU University Amsterdam AmsterdamNetherlands Henryk niewodniczanski Institute of nuclear Physics Polish Academy of Sciences KrakowPoland AGH-University of Science and Technology Faculty of Physics and Applied Computer ScienceKrakowPoland natio

A search for the doubly charmed baryon ■^+cc is performed through its decay to theΛ^+c K^-π^+ final state,using proton-proton collision data collected with the LHCb detector at centre-of-mass energies of 7,8 and 13 *** data correspond to a total integrated luminosity of 9 fb^-*** significant signal is observed in the mass range from 3.4 to 3.8 GeV/c^*** limits are set at 95%credibility level on the ratio of the ■^+cc production cross-section times the branching fraction to that ofΛ^+c and ■^++cc *** limits are determined as functions of the ■^+cc mass for different lifetime hypotheses,in the rapidity range from 2.0 to 4.5 and the transverse momentum range from 4 to 15 GeV/c.

关键词： charmed baryons limits on production of particles charmed quarks experimental tests

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导致成人与儿童患者30天脑室腹腔分流失败的原因分析（英文）

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中华神经外科疾病研究杂志 2018年第3期17卷 253-253页

作者： Anderson IA Saukila LF robins JMW Akhunbay-Fudge CY Goodden jr Tyagi AK Phillips n Chumas PD Department of neurosurgery Leeds General Infirmary

OBJECTIVE The aim of this study was to provide a comprehensive benchmark of 30-day ventriculoperitoneal(VP)shunt failure rates for a single institution over a 5-year study period for both adult and pediatric patients,to compare this with the results in previously published literature,and to establish factors associated with shunt *** A retrospective database search was undertaken to identify all VP shunt operations performed in a single,regional neurosurgical unit during a 5-year *** were collected regarding patient age,sex,origin of hydrocephalus,and whether the shunt was a primary or secondary *** notes were used to ascertain the type of valve inserted,which components of the shunt were adjusted/replaced(in revision cases),level of seniority of the most senior surgeon who participated in the operation,and number of surgeons involved in the *** appropriate and where available,postoperative imaging was assessed for grade of shunt placement,using a recognized grading *** and multivariate models were used to establish factors associated with early(30-day)shunt *** Six hundred eighty-three VP shunt operations were performed,of which 321 were pediatric and 362 were *** median duration of postoperative follow-up for nonfailed shunts(excluding deaths)was 1263 days(range 525-2226 days).The pediatric 30-day shunt failure rates in the authors'institution were 8.8%for primary shunts and 23.4%for *** adults,the 30-day shunt failure rates are 17.7%for primary shunts and 25.6%for *** pediatric procedures,the number of surgeons involved in the operating theater was significantly associated with shunt failure *** adults,the origin of hydrocephalus was a statistically significant *** shunts lasted longer than revision shunts,irrespective of patient *** A benchmark of 30-day failures is presented and is consistent with current national databases and previously p

关键词： Factors associated ventriculoperitoneal shunt failure

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alvimopan对接受简单腹式全子宫切除术患者安全性的一项双盲、随机、安慰剂对照Ⅲ期临床研究

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世界核心医学期刊文摘（妇产科学分册） 2006年第12期2卷 7-7页

作者： Herzog T.J. Coleman r.L. Guerrieri jr. J.P. 翁梨驹 Columbia University New YorkNYUnited States Dr.

Objective:The purpose of this study was to investigate the safety and efficacy of alvimopan,a novel peripherally acting mu-opioid receptor antagonist,in patients who undergo simple total abdominal hysterectomy. Study design:Women (n = 519)-were randomized (4:1) to receive alvimopan 12 mg (n = 413) or placebo (n = 106)≥2 hours before the operation then twice daily for 7 days (hospital and home). Adverse events were monitored up to 30 days after the last dose of study drug was administered. Efficacy was assessed for 7 postoperative days. results:Overall,the most common adverse events were nausea,vomiting,and constipation; nts discontinued use because of adverse events. Alvimopan significantly accelerated the time to first bowel movement (hazard ratio,2.33; P rage time to first bowel movement was reduced by 22 hours,with more frequent bowel movement and better bowel movement quality found in the treatment cohort. Conclusion:Alvimopan has a safety profile that is similar to that of placebo and provides significantly improved lower gastrointestinal recovery in women who undergo simple total abdominal hysterectomy.

关键词： alvimopan 安慰剂对照阿片受体拮抗剂排粪于术不良反应消化道功能研究设计随机分配

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Measurement of Ξcc++ production in pp collisions at s1/2=13 TeV

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Chinese Physics C 2020年第2期44卷 13-23页

作者： r.Aaij C.Abellán Beteta T.Ackernley B.Adeva M.Adinolfi H.Afsharnia C.A.Aidala S.Aiola Z.Ajaltouni S.Akar P.Albicocco J.Albrecht F.Alessio M.Alexander A.Alfonso Albero G.Alkhazov P.Alvarez Cartelle A.A.Alves jr S.Amato Y.Amhis L.An L.Anderlini G.Andreassi M.Andreotti F.Archilli A.Artamonov M.Artuso K.Arzymatov E.Aslanides M.Atzeni B.Audurier S.Bachmann J.J.Back S.Baker V.Balagura W.Baldini A.Baranov r.J.Barlow S.Barsuk W.Barter M.Bartolini F.Baryshnikov J.M.Basels G.Bassi V.Batozskaya B.Batsukh A.Battig A.Bay M.Becker F.Bedeschi I.Bediaga A.Beiter L.J.Bel V.Belavin S.Belin V.Bellee K.Belous I.Belyaev G.Bencivenni E.Ben-Haim S.Benson S.Beranek A.Berezhnoy *** D.Berninghoff H.C.Bernstein C.Bertella E.Bertholet A.Bertolin C.Betancourt F.Betti M.O.Bettler Ia.Bezshyiko S.Bhasin J.Bhom M.S.Bieker S.Bifani P.Billoir A.Bizzeti M.Bjørn M.P.Blago T.Blake F.Blanc S.Blusk D.Bobulska V.Bocci O.Boente Garcia T.Boettcher A.Boldyrev A.Bondar n.Bondar S.Borghi M.Borisyak M.Borsato J.T.Borsuk T.J.V.Bowcock C.Bozzi M.J.Bradley S.Braun A.Brea rodriguez M.Brodski J.Brodzicka A.Brossa Gonzalo D.Brundu E.Buchanan A.Buonaura C.Burr A.Bursche A.Butkevich J.S.Butter J.Buytaert W.Byczynski S.Cadeddu H.Cai r.Calabrese L.Calero Diaz S.Cali r.Calladine M.Calvi M.Calvo Gomez P.Camargo Magalhaes A.Camboni P.Campana D.H.Campora Perez A.F.Campoverde Quezada L.Capriotti A.Carbone G.Carboni r.Cardinale A.Cardini I.Carli P.Carniti K.Carvalho Akiba A.Casais Vidal G.Casse M.Cattaneo G.Cavallero S.Celani r.Cenci J.Cerasoli M.G.Chapman M.Charles Ph.Charpentier G.Chatzikonstantinidis M.Chefdeville V.Chekalina C.Chen S.Chen A.Chernov S.-G.Chitic V.Chobanova S.Cholak M.Chrzaszcz A.Chubykin P.Ciambrone M.F.Cicala X.Cid Vidal G.Ciezarek F.Cindolo P.E.L.Clarke M.Clemencic H.V.Cliff J.Closier J.L.Cobbledick V.Coco J.A.B.Coelho J.Cogan E.Cogneras L.Cojocariu P.Collins T.Colombo A.Comerma-Montells A.Contu n.Cooke G.Coombs S.Coquereau G.Corti C.M.Costa Sobral B.Couturier D.C.Craik J.Crkovska A.Crocombe M.Cruz Torres r.Currie C.L.Da Silva E.Dall'Occo J.Dalseno C.D' Centro Brasileiro de Pesquisas Físicas(CBPF) Rio de JaneiroBrazil Universidade Federal do rio de Janeiro(UFrJ) Rio de JaneiroBrazil Center for High Energy Physics Tsinghua UniversityBeijingChina School of Physics State Key Laboratory of nuclear Physics and Technology Peking UniversityBeijingChina University of Chinese Academy of Sciences BeijingChina Institute Of High Energy Physics(IHEP) BeijingChina Institute of Particle Physics Central China Normal UniversityWuhanHubeiChina Univ.Grenoble Alpes Univ.Savoie Mont BlancCNRSIN2P3-LAPPAnnecyFrance UniversitéClermont Auvergne CNRS/IN2P3LPCClermont-FerrandFrance Aix Marseille Univ CNRS/IN2P3CPPMMarseilleFrance LAL Univ.Paris-SudCNRS/IN2P3UniversitéParis-SaclayOrsayFrance LPnHE Sorbonne UniversitéParis Diderot Sorbonne Paris CitéCNRS/IN2P3ParisFrance I.Physikalisches Institut RWTH Aachen UniversityAachenGermany Fakultät Physik Technische Universität DortmundDortmundGermany Max-Planck-Institut für Kernphysik(MPIK) HeidelbergGermany Physikalisches Institut Ruprecht-Karls-Universität HeidelbergHeidelbergGermany School of Physics University College DublinDublinIreland InFn Sezione di Bari BariItaly InFn Sezione di Bologna BolognaItaly InFn Sezione di Ferrara FerraraItaly InFn Sezione di Firenze FirenzeItaly InFn Laboratori nazionali di Frascati FrascatiItaly InFn Sezione di Genova GenovaItaly InFn Sezione di Milano-Bicocca MilanoItaly InFn Sezione di Milano MilanoItaly InFn Sezione di Cagliari MonserratoItaly InFn Sezione di Padova PadovaItaly InFn Sezione di Pisa PisaItaly InFn Sezione di roma Tor Vergata RomaItaly InFn Sezione di roma La Sapienza RomaItaly nikhef national Institute for Subatomic Physics AmsterdamNetherlands nikhef national Institute for Subatomic Physics and VU University Amsterdam AmsterdamNetherlands Henryk niewodniczanski Institute of nuclear Physics Polish Academy of Sciences KrakówPoland AGH-University of Science and Technology Faculty of Physics and Applied Computer ScienceKrakówPoland nationa

The production of ■baryons in proton-proton collisions at a centre-of-mass energy of √s = 13 TeV is measured in the transverse-momentum range 4nd the rapidity range2.0n this measurement correspond to an integrated luminosity of 1.7fb^-1,recorded by the LHCb experiment during *** ratio of the ■ production cross-section times the branching fraction of the■→∧^+cK^-π^+ π^+decay relative to the prompt ∧^+c production cross-section is found to be(2.22±0.27±0.29)×10^-4,assuming the central value of the measured lifetime,where the first uncertainty is statistical and the second systematic.

关键词： doubly charmed baryons hadron production QCD

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强化降压治疗对糖尿病患者左心室肥厚的影响

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中华高血压杂志 2015年第9期23卷 899-899页

作者： Soliman EZ Byington rP Bigger JT Evans G Okin PM Goff DC jr Chen H 赵狄练桂丽

该研究纳入参加随机对照试验——＂控制糖尿病患者心血管风险行动＂试验中的4331例糖尿病患者,比较强化治疗（收缩压〈120 mm Hg,1 mm Hg=0.133kPa）与标准治疗（收缩压〈140 mm Hg）的作用,探讨降压治疗对左心室肥厚（left ventricular... 详细信息

该研究纳入参加随机对照试验——＂控制糖尿病患者心血管风险行动＂试验中的4331例糖尿病患者,比较强化治疗（收缩压〈120 mm Hg,1 mm Hg=0.133kPa）与标准治疗（收缩压〈140 mm Hg）的作用,探讨降压治疗对左心室肥厚（left ventricular hypertrophy,LVH）风险的影响。采用Cornell电压（二分类变量）及平均Cornell指数（连续变量）评估心电图LVH。基线时强化治疗组（n=2154）与标准治疗组（n=2177）的LVH发生率（5.3%比5.4%,

关键词：强化降压治疗左心室肥厚糖尿病患者 Cornell指数随机对照试验心血管风险标准治疗

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高结晶度羟基磷灰石涂层牙科种植体:5年前瞻性临床研究

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中国口腔种植学杂志 2012年第4期17卷 196-203页

作者： Todd Thierer John P.Davliakos J.Daulton Keith jr John J.Sanders Dennis P.Tarnow James A.rivers 王小容刘朴张艳纽约州罗彻斯特市罗彻斯特大学医疗中心南卡罗来纳州查尔斯顿市南卡罗来纳医科大学医学院南卡罗来纳州查尔斯顿市南卡罗来纳医科大学牙周学研究生院纽约州纽约市纽约大学牙科学院牙周学和牙科种植学系南卡罗来纳州查尔斯顿市南卡罗来纳医科大学修复牙科学系四川大学华西口腔医院成都市第一人民医院口腔科中国杰美公司

提高HA涂层的晶体含量能够使得它们在体内的耐降解能力比低结晶度的HA涂层高很多,但更高的结晶度也降低了表面可浸润性,这可能对组织附着和长期临床结果有不利的影响。本前瞻性研究的开展是为了确定在之前报道的浸润性降低的前提下,是... 详细信息

提高HA涂层的晶体含量能够使得它们在体内的耐降解能力比低结晶度的HA涂层高很多,但更高的结晶度也降低了表面可浸润性,这可能对组织附着和长期临床结果有不利的影响。本前瞻性研究的开展是为了确定在之前报道的浸润性降低的前提下,是否高结晶度HA涂层种植体能够符合最低85%的5年种植体成功率标准。研究对象是在3家大学牙科诊所和1家私人牙科诊所就诊,上颌和/或下颌有1或多个缺失牙齿的连续病人,共有120位病人按方案进行了治疗并且成功的用种植体支持修复体进行了修复。3位病人的4个种植体失败并从此研究中排除。没有出现其他无法解决的不良事件。5年时的累积成功率是97%(n=88位病人的184个种植体),超过了5年临床使用后种植体成功率85%的标准。

关键词：羟基磷灰石 HA 牙种植体结晶度浸润性

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Occurrence of Anguilla luzonensis in the Tributaries along the Lagonoy Gulf,Philippines

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Journal of Fisheries Science 2021年第1期3卷 8-16页

作者： Katrina L.Canon Plutomeo M.nieves Antonino B.Mendoza jr John Christopher C.nolial niño C.Celestial ronie O.Mediario raul G.Bradecina Teresa n.Avila Satoshi Kubota Graduate School of Integrated Arts and Sciences Kochi UniversityKohasuOkoNankokuKochi 783-8505Japan Bicol University Tabaco Campus Tabaco City 4511AlbayPhilippines Partido State University Goa 4422Camarines SurPhilippines

Anguillids areаvaluable fish commodity *** Anguilla luzonensis have been abundantly found in the northern Philippines and collected for trade,no available records show that it recruited in the mid-part where Lagonoy Gulf,Bicol is *** this study,we investigated the occurrence of *** in the tributaries along the Lagonoy Gulf,Philippines using molecular *** eel specimens were collected in 2018-2019 from the Comun river,Albay;the Lagonoy river,Camarines Sur;and the Bato river,*** luzonensis was first reported in Lagonoy Gulf using molecular *** was the second most abundant species in the Comun and Lagonoy rivers(9.5 and 22.4%,respectively).Anguilla luzonensis collected from the Comun and Lagonoy rivers did not show a significant difference(FST=0.00825,p>0.05).Anguilla marmorata was the most dominant species in all tributaries(71.1-98.0%).In the Comun and Lagonoy rivers,*** pacifica was the third most abundant species(7.7 and 6.5%,respectively).In addition,Anguilla celebesensis was only found rarely in the Comun river(0.9%).This study provides important information for sustainable resource management and effective utilization of the eel species in these regions.

关键词： Anguilla Glass eels Species composition PCr-rFLP DnA sequencing Diversity

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西罗莫司洗脱支架与血管内近距离放射疗法治疗裸金属支架内再狭窄的疗效比较:SISr随机试验

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世界核心医学期刊文摘（心脏病学分册） 2006年第8期2卷 6-6页

作者： Holmes jr. D. r. Teirstein P. Satler L. 马超(译) 杜媛(校) Mayo Clinic Division of Cardiovascular Diseases 200 First St SW Rochester MN 55905 United States 不详

Context: Although vascular brachytherapy is the only approved therapy for restenosis following bare-metal stent implantation, drug-eluting stents are now being used. Data on the relative merits of each are limited. Objective: To determine the safety and efficacy of the sirolimus-eluting stent compared with vascular brachytherapy for the treatment of patients with restenosis within a bare metal stent. Design, Setting, and Patients: Prospective, multicenter, randomized trial of 384 patients with in-stent restenosis who were enrolled between February 2003 and July 2004 at 26 academic and community medical centers. Data presented represent all follow-up as of June 30, 2005. Interventions: Vascular brachytherapy(n=125) or the sirolimus-eluting stent(n=259). Main Outcome Measure: Target vessel failure(cardiac death, myocardial infarction, or target vessel revascularization)at 9 months postprocedure. results: Baseline patient characteristics were well matched. Lesion length was similar between vascular brachytherapy and sirolimus-eluting stent patients(mean [SD], 16.76 [8.55] mm vs 17.22 [7.97] mm, respectively; P=.61). Procedural success was 99.2% (124/125) in the vascular brachytherapy group and 97.3% (250/257) in the sirolimus-eluting stent group(P=.28). The rate of target vessel failure was 21.6% (27/125) with vascular brachytherapy and 12.4% (32/259) with the sirolimus-eluting stent(relative risk [rr], 1.7; 95% confidence interval [CI], 1.1-2.8; P=.02). Target lesion revascularization was required in 19.2% (24/125) of the vascular brachytherapy group and 8.5% (22/259) of the sirolimus-eluting stent group(rr, 2.3 [95% CI, 1.3-3.9]; P=.004). At follow-up angiography, the rate of binary angiographic restenosis for the analysis segment was 29.5% (31/105) for the vascular brachytherapy group and 19.8% (45/227) for the sirolimus-eluting stent group(rr, 1.5 [95% CI, 1.0-2.2]; P=.07). Compared with the vascular brachytherapy group, minimal lumen diameter was larger in the sir

关键词：血管内放射治疗支架内再狭窄药物洗脱支架金属支架随机试验西罗莫司近距离放射疗法疗效比较社区医疗中心支架治疗

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不稳定型心绞痛和PTCA术后患者血小板和白细胞的黏附和激活

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世界核心医学期刊文摘（心脏病学分册） 2005年第9期1卷 50-50页

作者： Serrano jr. C.V. rocha Giraldez r. De Lara Fernandes J. 孙凯 Heart Institute(InCor) Univ. of S. Paulo Medical School Av. Dr. E. de Carvalho Aguiar 44 So Paulo SP-05403-000 Brazil

Background: Unstable atherosclerotic plaques activate blood cells which may adhere to the coronary endothelium causing vessel occlusion. However, it is unknown if different clinical syndromes associated with plaque rupture induce similar blood cell activation and adhesion to the endothelium. Methods: We studied changes in adhesion molecule expression of platelets(GPIIb/IIIa), neutrophils -CD18, CD11b and L-selectin -and monocytes(CD14) after interaction with active lesions of patients with stable angina subjected to PTCA and patients with unstable angina(UA). Generation of superoxide(SO) radicals from PMns and PMn sequestration in the coronary circulation were also assessed. Blood samples were collected from the aorta(Ao) and coronary sinus(CS) before and 15 min after PTCA(n=13) and within the first 48 h of UA(n=12). results: PTCA induced a marked up-regulation of CD18, CD11b, CD14 and GPIIb/IIIa with L-selectin shedding and reduced SO formation, whereas only minor L-selectin down-regulation and decreased SO production indicated activation in UA. However, a significant decrease in neutrophil count in the CS compared to the Ao was only observed in UA. Conclusions: The magnitude of cellular activation depends on the underlying clinical setting and just partially contributes to cell adhesion to the endothelium which might be modulated by different extent of vascular occlusion and shear forces.

关键词：不稳定型心绞痛 PTCA术选择素冠状动脉循环稳定斑块斑块破裂黏附分子冠状窦临床综合征中性粒细胞

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Impaired swallowing mechanics of post radiation therapy head and neck cancer patients: A retrospective videofluoroscopic study

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World Journal of radiology 2016年第2期8卷 192-199页

作者： William G Pearson jr Alisa A Davidoff Zachary M Smith Dorothy E Adams Susan E Langmore Department of Cellular Biology and Ana-tomy Medical College of Georgia at Georgia Regents University Department of Otolaryngology Medical College of Georgia at Georgia Regents University Sargent College Boston University Department of Otolaryngology Head and neck Surgery Boston University School of Medicine

AIM: To determine swallowing outcomes and hyolaryngeal mechanics associated with post radiation therapy head and neck cancer(rt HnC) patients using videofluoroscopic swallow studies. METHODS: In this retrospective cohort study, video-fluoroscopic images of rt HnC patients(n = 21) were compared with age and gender matched controls(n = 21). Penetration-aspiration of the bolus and bolus residue were measured as swallowing outcome variables. Timing and displacement measurements of the anterior and posterior muscular slings elevating the hyolaryngeal complex were acquired. Coordinate data of anatomical landmarks mapping the action of the anterior muscles(suprahyoid muscles) and posterior muscles(long pharyngeal muscles) were used to calculate the distance measurements, and slice numbers were used to calculate time intervals. Canonical variate analysis with post-hoc discriminant function analysis was performed on coordinate data to determine multivariate mechanics of swallowing associated with treatment. Pharyngeal constriction ratio(PCr) was also measured to determine if weak pharyngeal constriction is associated with post radiation ***: The rt HnC group was characterized by poor swallowing outcomes compared to the control group in regards to: Penetration-aspiration scale(P normalized residue ratio scale(nrrS) for the valleculae(P = 0.002) and nrrS for the piriform sinuses(P = 0.003). Timing and distance measurements of the anterior muscular sling were not significantly different in the two groups, whereas for the PMS time of displacement was abbreviated(P = 0.002) and distance of excursion was reduced(P = 0.02) in the rt HnC group. A canonical variate analysis shows a significant reduction in pharyngeal mechanics in the rt HnC group(P r was significantly higher in the test group than the control group(P = 0.0001) indicating reduced efficiency in pharyngeal clearance. COnCLUSIOn: Using videofluoroscopy, this study shows rt HnC pati

关键词： Swallow mechanics Post radiation Head and neck cancer Fluoroscopy Anatomy

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