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A Hybrid Approach for COVID-19 Detection Using Biogeography-Based Optimization and Deep Learning

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Computers, Materials & Continua 2022年第2期70卷 3717-3732页

作者： k.Venkatachalam Siuly Siuly M.Vinoth kumar Praveen lalwani Manas kumar Mishra Enamul kabir Department of Computer Science and Engineering CHRIST(Deemed to be University)Bangalore560074India Institute for Sustainable Industries&Liveable Cities Victoria UniversityMelbourne14428Australia Department of Computer Science and Engineering Anna UniversityUniversity College of EngineeringDindigul624622India School of Sciences University of Southern QueenslandToowoombaDarling Heights4350Australia

The COVID-19 pandemic has created a major challenge for countries all over the world and has placed tremendous pressure on their public health care *** early diagnosis of COVID-19 may reduce the impact of the *** achieve this objective,modern computation methods,such as deep learning,may be *** this study,a computational model involving deep learning and biogeography-based optimization(BBO)for early detection and management of COVID-19 is ***,BBO is used for the layer selection process in the proposed convolutional neural network(CNN).The computational model accepts images,such as CT scans,X-rays,positron emission tomography,lung ultrasound,and magnetic resonance imaging,as *** the comparative analysis,the proposed deep learning model CNNis compared with other existingmodels,namely,VGG16,InceptionV3,resNet50,and *** the fitness function formation,classification accuracy is considered to enhance the prediction capability of the proposed *** results demonstrate that the proposed model outperforms InceptionV3 and resNet50.

关键词： Covid-19 biogeography-based optimization deep learning convolutional neural network computer vision

Efficient discrete firefly algorithm for Ctrie based caching of multiple sequence alignment on optimally scheduled parallel machines

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CAAI Transactions on Intelligence Technology 2019年第2期4卷 92-100页

作者： Soniya lalwani Harish Sharma Abhay Verma rajesh kumar Department of Computer Science & Engineering Rajasthan Technical University Kota India Department of Electrical Engineering Malaviya National Institute of Technology Jaipur India

This study introduces a two-level strategy for efficient execution of multiple sequence alignment (MSA) of complex heterogeneous sequences. The two levels of the proposed technique are comprised of: designing the discrete firefly algorithm (DFFA) for the formation and implementation of makespan minimisation on parallel machines, followed by performing Ctrie-based caching for pairwise alignment to reduce the load on the data servers for handling multiple queries. The proposed strategy addresses a multi-client problem that aims to acquire the full advantage of the computational power of parallel connected machines. Further, it is shown that the inclusion of Ctrie as caching mechanism successively improves the performance of the system with accretion in several sequences. Performance of proposed DFFA is also compared with discrete versions of four swarm intelligence based algorithms at the criteria of makespan minimisation and the rate of convergence on two kinds of complex and diverse datasets. The work is unique in this sense: it is the first swarm-intelligence-based implementation for the addressed problem;it is so far the first approach for Ctrie based caching of the MSA on the scheduled parallel machines;hybridisation of DFFA with Ctrie for caching the MSA results is also a novel implementation.

关键词： strategy execution machines

Preparation and evaluation of transnasal microemulsion of carbamazepine

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Asian Journal of Pharmaceutical Sciences 2013年第1期8卷 64-70页

作者： Sheetal Porecha Acharya k.Pundarikakshudu Aashish Panchal Anita lalwani l.10.institute of pharmacy and research centre ahmedabadgujarat 382210india kadi sarva vishwavidyalaya sector 15/23gandhinagargujaratindia

The objective of this study was to develop novel transanasl microemulsion containing carbamazepine for treatment of *** acid was selected as oil while Tween 80 and propylene glycol were selected as surfactant and cosurfactant respectively based on solubility *** ratio of Tween 80:propylene glycol was selected after developing pseudoternary phase diagrams for different ratio and microemulsions were *** prepared microemulsions were evaluated for globule size,viscosity,pH,conductivity and%*** diffusion study for optimized microemulsion was performed through sheep nasal mucosa wherein diffusion flux and permeability coefficients were *** pharmacodynamic performance was evaluated in rats by electrically induced *** was found that optimized microemulsion was stable and transparent with average globule size of 190 nm and diffusion flux of 75.77 mg cm2 min1 and showed no toxicity during histopathological evaluation on sheep nasal *** evaluation also indicated lesser intensity of seizures in rats treated with optimized formulation in comparison to rats treated with oral carbamazepine microemulsion and nasal carbamazepine solution which suggested carbamazepine transnasal delivery system as an effective alternate therapy for treatment of epilepsy.

关键词： Carbamazepine Epilepsy Intranasal Microemulsion

Identification and Classification of Multiple Power Quality Disturbances Using a Parallel Algorithm and Decision rules

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Energy Engineering 2022年第2期119卷 473-497页

作者： Nagendra kumar Swarnkar Om Prakash Mahela Baseem khan Mahendra lalwani Department of Electrical Engineering Rajasthan Technical UniversityKotaIndia Power System Planning Division Rajasthan Rajya Vidyut Prasaran Nigam LimitedJaipurIndia Department of Electrical and Computer Engineering Hawassa UniversityAwassaEthiopia

A multiple power quality(MPQ)disturbance has two or more power quality(PQ)disturbances superimposed on a voltage signal.A compact and robust technique is required to identify and classify the MPQ *** manuscript investigated a hybrid algorithm which is designed using parallel processing of voltage with multiple power quality(MPQ)disturbance using stockwell transform(ST)and hilbert transform(HT).This will reduce the computational time to identify theMPQdisturbances,whichmakes the algorithm fast.A MPQ identification index(IPI)is computed using statistical features extracted from the voltage signal using the ST and *** has different patterns for various types of MPQ disturbances which effectively identify the MPQ disturbances.A MPQ time location index(IPL)is computed using the features extracted from the voltage signal using ST and *** effectively identifies the initiation and end of PQ disturbances and thereby locates the MPQ events with respect to *** of MPQ disturbances is performed using decision rules in both the noise-free and noisy environments with a 20 dB noise to signal ratio(SNr).The performance of the proposed hybrid algorithm using ST and HT with rule-based decision tree(rBDT)is better compared to the ST and rBDT techniques in terms of accuracy of classification of MPQ *** software is used to perform the study.

关键词： Decision rules hilbert transform multiple PQ disturbance power quality stockwell transform

Comparative study of CEA and CA19-9 in esophageal,gastric and colon cancers individually and in combination(rOC curve analysis)

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Cancer Biology & Medicine 2013年第3期10卷 148-157页

作者： Bhawna Bagaria Sadhna Sood rameshwaram Sharma Soniya lalwani Department of Biochemistry S.M.S.Medical College & Hospital Department of radiotherapy and Oncology S.M.S.Medical College & Hospital Advanced Bioinformatics Centre Birla Institute of Scientific Research

Objective： To determine the clinical serum levels of carcinoembryonic antigen （CEA） and carbohydrate antigen 19-9 （CA19-9）, individually and in combination, for the diagnosis of 50 healthy subjects and 150 cases of esophageal, gastric, and colon cancers. Methods： The sensitivities of the two markers were compared individually and in combination, with specificity set at 100%. receiver operating characteristic （rOC） curves were plotted. results： Serum CEA levels were significantly higher in cancer patients than in the control group. The sensitivity of CEA was determined： in esophageal cancer, sensitivity=28%, negative predictive value （NPV）=61.72%, and AUC=0.742 （SE=0.05）, with a significance level of P〈0.0001; in gastric cancer, sensitivity=30%, NPV=58.82%, and AUC=0.734 （SE=0.0S）, with a significance level of P〈0.0001; in colon cancer, sensitivity=74%, NPV=79.36%, and AUC=0.856 （SE=0.04）, with a significance level of P〈0.0001. The sensitivity of CA19-9 was also evaluated： in esophageal cancer, sensitivity=18%, NPV=54.94%, and AUC=0.573 （SE=0.05）, with a significance level of P=0.2054. In gastric cancer, sensitivity=42%, NPV=63.29%, and AUC=0.679 （SE=0.05）, with a significance level of P〈0.0011. In colon cancer, sensitivity=26%, NPV=57.47%, and AUC=0.S80 （SE=0.05）, with a significance level ofP=0.1670. The following were the sensitivities of CEA/CA19-9 combined： in esophageal cancer, sensitivity=42%, NPV=63.29%, SE=0.078 （95% CI： 0.0159-0.322）; gastric cancer, sensitivity=S8%, NPV=70.42%, SE=0.072 （9$% CI： -0.0866-0.198）; and colon cancer, sensitivity=72%, NPV=78.12%, SE=0.070 （9S% CI： 0.137-0.415）. Conclusion： CEA exhibited the highest sensitivity for colon cancer, and CA19-9 exhibited the highest sensitivity for gastric cancer. Combined analysis indicated an increase in diagnostic sensitivity in esophageal and gastric cancer compared with that in colon cancer.

关键词： Carcinoembryonic antigen carbohydrate antigen 19-9, human receiver operating characteristic curve sensitivity andspecificity

Successful resection in a Case of Hepatocellular Carcinoma Masquerading as Hilar Cholangiocarcinoma: A Case report

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Journal of Clinical and Translational Hepatology 2018年第4期6卷 442-446页

作者： Prakriti Gupta Shashi Dhawan Vivek Mangla Siddharth Mehrotra Shailendra lalwani Naimish N Mehta Samiran Nundy Department of Pathology Sir Ganga Ram HospitalNew DelhiIndia Department of Surgical Gastroenterology and Liver Transplantation Sir Ganga Ram HospitalNew DelhiIndia

Obstructive jaundice in the setting of a hilar mass raises strong suspicion of a cholangiocarcinoma,with diagnosis usually made on ***,when present in patients with hepatocellular carcinoma,is mostly related to underlying liver disease(***)and only rarely to diffuse tumor infiltration of liver parenchyma or hilar *** report here the good outcome of a 67 year-old patient who presented with obstructive jaundice,underwent surgery and was given a diagnosis of hepatocellular carcinoma,which was made only at histopathological examination of resected specimen.

关键词： Obstructive jaundice Hepatocellular carcinoma Cholangiocarcinoma

Proximal Femoral Nail in reverse Trochanteric Femoral Fractures: An Analysis of 53 Cases at One Year Follow-Up

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Surgical Science 2016年第7期7卷 300-308页

作者： Yogesh Salphale Wasudeo Mahadeo Gadegone Alankar ramteke Nirbhay karandikar raviraj Shinde Prakash lalwani Department of Orthopaedics & Traumatology Chandrapur Multispeciality Hospital Chandrapur India

Treatment of reverse oblique trochanteric femoral fractures poses a lot of challenges. There have been proponents of intramedullary devices as well as extramedullary devices. We present the results of proximal femoral nailing surgery performed for reverse obliquity intertrochanteric fractures using two proximal lag screws and a nail of 250 mm. There is prospective study of fifty three patients with AO/OTA 31 A-A3 fractures being treated by proximal femoral nailing in our institute after seeking approval from the Hospital ethics board. The quality of the reduction, the operative time, complications and the functional status of the patients were the parameters on which the results were evaluated. The mean Harris hip score was 76.66 (range 70 - 93) and the mean Barthel activity score was 16.21 (range 12 - 20). The average surgical time was 50 minutes and the mean consolidation time was 11.5 weeks. Intramedullary nailing with proximal femoral nails seems to be a good option in the treatment of reverse obliquity intertrochanteric fractures as against the various existing options available for the management.

关键词： Proximal Femoral Nailing reverse Obliquity Intertrochanteric Fractures Intramedullary Nailing PFN Cephalomedullary Nail Hip Fracture

Parosteal Lipoma of Femur—A Case report

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Surgical Science 2015年第12期6卷 549-554页

作者： Yogesh S. Salphale Prakash lalwani Wasudeo M. Gadegone Ajay Mehra ravi Alurwar Department of Orthopaedic & Traumatology Chandrapur Multispeciality Hospital Chandrapur India

A case of 16 yrs male patient with parosteal lipoma affecting the lower metaphyseal end of the left femur is presented. Clinical suspicion, plain radiographs, CT (Plain and 3 D) as well as MrI suggested a diagnosis of parosteal lipoma. Lipomas may be defined as benign lesions of mature adipose tissue without evidence of cellular atypia [1]. Lipomas are the most common soft tissue lesions and surprisingly are among the rarest bone neoplasias. The most frequent complaints are a tumoral convexity presenting as a visible or palpable mass or a mild-intensity, dull pain. The parosteal type is a rare tumor accounting for 0.3% of all lipomas [2] and is usually asymptomatic. It is seen commonly affecting adults aged over 40 [3]. The present article describes a rare case of parosteal lipoma located in the femur, with extensive hyperostosis visible on plain xray and confirmed by imaging studies (CT and MrI). Unlike the parosteal lipomas reported in adults over 40 yrs in this case it presented in a much younger age group.

关键词： Parosteal Lipoma Nonpulsatile Mass Tumoral Mass

Proximal Femoral Nailing: Getting the Trajectory right

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Surgical Science 2016年第5期7卷 235-238页

作者： Yogesh Salphale Prakash lalwani Bhaskaran Shivashankar Wasudeo Mahadeo Gadegone kiran Janwe Satyajeet Jagtap Department of Orthopaedics & Traumatology Chandrapur Multispeciality Hospital Chandrapur India

Getting the trajectory of the proximal femoral nail in the right direction is essential to achieve a good result in the technically demanding surgery of proximal femoral fracture. Either an inappropriate starting point or a failure to match the chosen implant’s lateral entry angle may cause coronal plane deformity after trochanteric entry nailing. The lateral view is the critical view for localization of the proper starting point. For the right execution of the surgery, getting the trajectoy right is fully under the control of the surgeon and should always be attempted.

关键词： PFN Proximal Femoral Fracture Unstable Pertrochanteric Fracture Nail Trajectory