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儿童大剂量移植HLA不相合双亲供者的纯化外周血CD34^+祖细胞

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德国医学 2001年第6期18卷 344-346页

作者：王震张玉平李扬秋 r.Handgretinger T.Klingebiel P.Lang M.Schumm S.Neu P.Bader A.Geiselhart P.G.Schlegel j.Greil D.Stachel r.j.herzog D.Niethammer 暨南大学医学院血液病研究所 Department of Pediatric H ematology/Oncology and Blood Bank University of TübingenTübingen Germany

对于许多恶性和非恶性疾病来说,进行清髓性造血祖细胞异基因移植是唯一行之有效的治疗措施,但大多数需要移植的患者无组织相容性的同胞供者.与同胞移植相比,无关供者移植的移植物抗宿主病(GVHD)、移植排斥和感染的发病率及严重程度均增... 详细信息

对于许多恶性和非恶性疾病来说,进行清髓性造血祖细胞异基因移植是唯一行之有效的治疗措施,但大多数需要移植的患者无组织相容性的同胞供者.与同胞移植相比,无关供者移植的移植物抗宿主病(GVHD)、移植排斥和感染的发病率及严重程度均增加,故移植效果较差 . 若能采用不用进行HLA配型的单倍体供者,由于其快捷的可用性,将提供一些优势.几乎所有可能进行异基因移植的患者都将会在一个特定的时间内找到供者.与应用脐血干细胞移植比较,单倍体供者在发生未植活或排斥反应的情况下仍然可以利用.其后如需要进行移植后免疫治疗如供体淋巴细胞输注时,也可以随时加以利用.然而在过去,清除T细胞的单倍体的移植使急慢性GVHD、未植活或移植物排斥的发病率增加以及免疫失调时间延长,这样就增加了致命性感染和淋巴细胞增殖性疾病的危险.

关键词：儿童骨髓移植 HLA配型 CD34^+祖细胞

在腰骶异常过度中髂腰韧带能否作为腰5椎体的一个可靠的标识符?

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国际医学放射学杂志 2014年第6期 612-612页

作者： N.A.Farshad-Amacker B.Lurie r.j.herzog M.Farshad 蒋光耀 MrI Radiology DepartmentHospital for Special Surgery535 East 70th StreetNew York 10021NYUSA

摘要目的足够样本量的研究来明确髂腰韧带(ILL)在腰骶移行(LSTV)中不能作为腰5(L5)椎体的标识点。方法从770例LSTV病例中选取71例作为病例组,从611例L5椎

关键词：椎体标识点髂腰韧带放射科

椎间盘、终板与椎体骨髓是脊柱退变进程的整体单元

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国际医学放射学杂志 2017年第4期 493-493页

作者： N.A.Farshad-Amacker A.Hughes r.j.herzog B.Seifert M.Farshad 孙海涛 MrI Radiology Department Hospital for Special SurgeryNew York NY USA

摘要目的椎间盘退变(DD)与椎体终板退变(EPD)的关系尚不清楚。本研究旨在寻找节段性DD与EPD的风险预测因素,进而揭示椎间盘、终板和骨髓在退变进程中的变化。方法经伦理委员会批准,对MrI随访至少4年的450个腰椎节段进行回顾性分析,按照P...

摘要目的椎间盘退变(DD)与椎体终板退变(EPD)的关系尚不清楚。本研究旨在寻找节段性DD与EPD的风险预测因素,进而揭示椎间盘、终板和骨髓在退变进程中的变化。方法经伦理委员会批准,对MrI随访至少4年的450个腰椎节段进行回顾性分析,按照Pfirrmann(PFG)标准进行DD分级,按照终板评分(EPS)以及Modic改变(MC)的存在、范围和类型对EPD进行分型。巢式病例对照亚型相匹配,并采

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A comparison of lower limb stiffness and mechanical muscle function in ACL-reconstructed,elite,and adolescent alpine ski racers/ski cross athletes

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journal of Sport and Health Science 2018年第4期7卷 416-424页

作者： matthew j.jordan per aagaard walter herzog canadian sport institute calgary Calgary AB T2N 1N4 Canada department of sports science and clinical biomechanics sdu muscle research clusteruniversity of southern denmarkOdense DK-5230Denmark human performance laboratory university of calgaryCalgary AB T2N 1N4Canada

Purpose: The aim of this study was to compare mechanical muscle function in the eccentric/concentric phases of vertical bilateral jumping in anterior cruciate ligament-reconstructed(ACLr), elite(ELITE), and adolescent(ADOL) alpine ski racers and ski cross ***: Alpine ski racers/ski crossers(ACLr: n = 12, age = 26.7 § 3.8 years; ELITE: n = 12, age = 23.9 § 3.0 years; ADOL: n = 12, age = 17.8§ 0.7 years; females: n = 6 per group, males: n = 6 per group) performed 5 maximal countermovement jumps(CMjs) and 5 squat jumps. The ground reaction forces for each limb were analyzed using dual force plate recording to obtain body center of mass(BCM) velocity, displacement,and power. The eccentric deceleration(ECC) and concentric phases were determined from BCM velocity. CMj net concentric and ECC impulses were calculated(body mass normalized) along with the peak and mean BCM power and maximal vertical jump height. CMj lower limb stiffness(LLS) was determined by the slope of the ground reaction forces vs. the BCM displacement curve over the ECC phase. Concentric and ECC asymmetry indices were calculated for each leg, and the left vs. right LLS was compared. Outcome measures(reported as mean § SD) calculated as a 5-jump mean were normalized to body mass and compared using an analysis of ***: No between-group differences were found for peak and mean power or jump heights. There were no group differences for LLS or net concentric phase impulse, but the net ECC impulse was lower in the ADOL group compared with ELITE skiers(ADOL: 1.33 § 0.32 Ns/kg;ELITE: 1.59 § 0.16 Ns/kg; p roup differences were found for ECC asymmetry indices, a group ￡ limb interaction was found for LLS(p r in the right vs. the left limb of ADOL skiers(right: 54.1 § 17.9 N/m/kg; left: 48.7 §15.7 N/m/kg; p rs demonstrated decreased ECC impulse and systematic right limb dominance in LLS compared with A

关键词：运动员滑雪高山肌肉机械僵硬 ACL 青春期

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Improved optical enhancement using double-width plasmonic gratings with nanogaps

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Photonics research 2016年第5期4卷 173-180页

作者： Ahmad A.Darweesh Stephen j.Bauman joseph B.herzog Microelectronics-Photonics Graduate Program University of Arkansas Department of Physics University of Arkansas

Plasmonic grating structures have been shown effective at increasing near-field optical enhancement. A doublewidth plasmonic grating design is introduced, where each period has two alternating metal widths separated by a nanogap. With this new design, analysis has shown that plasmonic resonances couple between each metal section,resulting in even greater optical enhancement compared with single-width gratings. The geometry that gives the greatest optical enhancement has been determined with a computational model. This work demonstrates that the increased enhancement is due to hybridized modes that couple between the two grating segments.

关键词： Improved optical enhancement using double-width plasmonic gratings with nanogaps nm

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Near-infrared metal-semiconductor-metal photodetector based on semi-insulating GaAs and interdigital electrodes

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Photonics research 2015年第1期3卷 1-4页

作者： A.I.Nusir A.M.Hill M.O.Manasreh j.B.herzog Electrical Engineering Department University of Arkansas Department of Physics University of Arkansas

Metal-semiconductor-metal photodetectors on semi-insulating Ga As with interdigital electrodes showed significant enhancement in the spectral response in the near-infrared region as the electrode spacing is reduced. The photocurrent for the device with 5 μm interdigital spacing is five orders of magnitude higher than the dark current, and the room temperature detectivity is on the order of 2.4 × 1012cm Hz1∕2W-1at 5 V bias. Furthermore,the spectral response of this device possesses strong dependence on the polarization of incident light showing potential plasmonic effects with only microscale dimensions. These experimental data were analyzed using optical simulation to confirm the response of the devices.

关键词： Ga As Near-infrared metal-semiconductor-metal photodetector based on semi-insulating GaAs and interdigital electrodes

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巴伐利亚登山救援国家安全及教育中心

城市环境设计 2016年第3期 54-63页

作者： Thomas herzog Hanns j?rg Schrade Verena herzog-Loibl Christoph Stepan herzog+Partner Archiv herzog+Partner

设计任务是为山地救援队设计一个可容纳山地以及空中救援模拟训练设施的透明训练厅,同时也要满足其他团体和机构,例如水上救援队、消防队和警察部队等的使用需求。同时训练厅内还需设置培训教室、技术设备房以及储藏室等侧室。倾斜的场... 详细信息

设计任务是为山地救援队设计一个可容纳山地以及空中救援模拟训练设施的透明训练厅,同时也要满足其他团体和机构,例如水上救援队、消防队和警察部队等的使用需求。同时训练厅内还需设置培训教室、技术设备房以及储藏室等侧室。倾斜的场地使设计可以将所有的功能全部嵌入山坡内,从而得到一个简洁的

关键词：建筑表皮山地利亚平面图图(数学) 救援队

股骨头坏死的诊断磁共振与同位素闪烁摄影、常规X线片的诊断性能之比较

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放射学实践 1988年第4期 152-157页

作者： Von j.herzog 李贵林 radiologische Klinik der Universitat Tubingen Abteilung fur Nuklearmedizin 同济医科大学附属同济医院

特发性股骨头坏死(HKN),30—60岁男性多见(男:女为4:1)。病因不明的股骨头部分供血中断致受累区缺血性坏死。股骨头前、上、外侧部最易受累,双侧受累者可达50％。一般来说,坏死区似一倒置的圆锥形。表面的关节软骨,早期并未被罹及。病... 详细信息

特发性股骨头坏死(HKN),30—60岁男性多见(男:女为4:1)。病因不明的股骨头部分供血中断致受累区缺血性坏死。股骨头前、上、外侧部最易受累,双侧受累者可达50％。一般来说,坏死区似一倒置的圆锥形。表面的关节软骨,早期并未被罹及。病情继续发展,形成软骨下骨坏死溶解,完整的关节软骨在负重情况下发生相应的股骨头畸形。

关键词：磁共振检查坏死区股骨头坏死不要命的癌症关节软骨摄影美术常规同位素

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用于流量计量的光纤涡旋传感器

中国检验检测 1993年第1期 43-45页

作者： j.P.herzog 夏永健

1.前言在许多生产过程中都需要准确测定流量。这种测量通常分成两步进行,先由主装置把流量转换成某一物理量(例如差压或频率),然后用辅助传感器予以检测,转换成电测量信号。

关键词：光纤光导纤维涡旋流量计量热工测量传感器换能器电子技术