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国际医学放射学杂志 2023年第1期46卷 105-106页

作者： G.H.Lee A.Chatterjee I.Karademir r.engelmann A.Yousuf M.Giurcanu 符小花

摘要由于阅片者的经验和对病变特征的主观评价,尽管采用了前列腺影像报告和数据系统(PI-rADS)2.1版,多参数前列腺MrI(mpMrI)的判读和阐述仍存在差异。多维混

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胸部影像学小肺癌:使用骨抑制成像提高检出——与双能量减影胸部成像的对比

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国际医学放射学杂志 2012年第1期 88-88页

作者： r.engelmann L.L.Pesce K.Doi C.E.Metz H.MacMahon 于寰 Department of radiology MC-2026University of Chicago5841 S Maryland AveChicagoIL 60637

目的明确骨抑制成像结合标准的胸片是否比单纯的标准胸片可提高放射学医师对小肺癌检测的能力,以及骨抑制成像的准确性是否与双能量减影片相当。材料与方法研究获机构审查委员会批准并符合HIPAA,无需知情同意。

关键词：小肺癌图像双能量减影胸片

Clinical practice guidelines for acute-on-chronic liver failure: are we ready for reaching global consensus?

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Hepatobiliary Surgery and Nutrition 2023年第2期12卷 239-243页

作者： Cornelius engelmann Thomas Berg Department of Hepatology and Gastroenterology CharitéUniversitätsmedizin BerlinBerlinGermany Division of Hepatology Department of Medicine IILeipzig University Medical CenterLeipzigGermany Berlin Institute of Health(BIH) BerlinGermany University College London Institute for Liver and Digestive HealthLondonUK

The concept of acute-on-chronic liver failure(ACLF)has gained increasing awareness during the last *** considers liver cirrhosis as a systemic disease where precipitating events lead to a sudden deterioration,decompensation and extrahepatic organ *** severity is determined by the number and types of organ failures and patients with ACLF have a distinct and worse prognosis than patients with acute decompensation but not fulfilling ACLF criteria(1-3).

关键词： Acute-on-chronic liver failure(ACLF) granulocyte-colony stimulating factor(G-CSF) cirrhosis

Metal Complexes:Novel Chiral Dopants with High Helical Twisting Power in Liquid Crystals

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复旦学报（自然科学版） 2007年第5期46卷 724-725页

作者： Manfred Braun r.Fleischer A.Hahn M.engelmann S.Schlecht Institute of Organic and Macromolecular Chemistry University of DuesseldorfD-40225 DuesseldorfGermany

1 Introduction A particularly efficient and elegant route to chiral mesophases is based on the addition of small amounts of an enantiomerically pure dopant to a nematic phase so that the latter is converted into a cholesteric phase(See Fig.1).Fig.1 A nematic phase is converted into a cholesteric phase Fig.2 Bis-chelated imine-alkoxy-titanium complexes2 ExperimetalBis-chelated imine-alkoxy-titanium complexes like 1 and 2 (Fig.2) have been synthesizedstarting from triphenyl-substituted aminoethanols, T...

关键词： metal complexes novel chiral dopants liguid crystals

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Human rights and Nanotechnologies： Limits and Possibilities Between Technological Innovation and rights of the Human

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Sociology Study 2011年第2期1卷 101-114页

作者： Wilson engelmann University of the Sinos Valley Rio Grande do Sul Brazil

Nanotechnology currently represents one of the most fascinating human discoveries. With creativity, nanotechnology looks for increasingly smaller spaces in nature to meet the needs and interests of the individuals and of the society. Considering that the researches aim to create techniques to move and combine atoms and molecules, a question arises, how will these atoms and molecules behave in the new arrangement. This is the great challenge and this article attempts to bring some benefits to the subiect. It also intends to bring the human sciences, particularly law, to the scenery of this scientific revolution. The lack of regulatory frameworks does not allow humans to search and produce anything without limits. Thus, human rights should be considered an ethical foundation for nanotechnology discoveries, as they represent the ＂rights＂ that, at least, humans should have respected.

关键词： Human rights nanotechnology regulatory frameworks risks environment

Effect of 24-Epibrassinolide on Growth of <i>in Vitro</i>Shoot Tips of Different Yam (<i>Dioscorea</i>Spp.) Species

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American Journal of Plant Sciences 2013年第11期4卷 2271-2274页

作者： Isabelle engelmann-Sylvestre Florent engelmann IrD UMR DIADE Agropolis Montpellier France

In this work we compared the effect of the growth regulator content of the culture medium on the growth of in vitro shoot tips of five yam accessions belonging to four yam species (one Dioscorea alata, one D. rotundata, one D. cayenensis and two D. trifida). Medium S contained 0.6 μM benzyl adenine, 1.07 μM naphthalene acetic acid and 0.23 μM gibberellic acid while medium EBr contained 0.23 μM gibberellic acid and 0.1 μM 24-epibrassinolide. After 2 months of culture, oxidation level was significantly reduced on medium EBr compared to medium S for four of the five accessions tested. By contrast, medium EBr did not have any positive effect on shoot length since length of shoots produced after 2 months of culture on medium S and EBr were similar, except with accession 3-45T, for which shoot length was shorter on medium S compared to medium EBr. These results underline the potential of 24-epibrassinolide to reduce oxidation phenomena during in vitro culture and call for its utilization for regeneration of cryopreserved yam shoot tips, which is often impeded by oxidation phenomena.

关键词： Yam Dioscorea Spp. 24-Epibrassinolide Oxidation Shoot Tip In Vitro Culture Cryopreservation

Improved spontaneous erectile function in men with mild-tomoderate arteriogenic erectile dysfunction treated with a nightly dose of sildenafil for one year： a randomized trial

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Asian Journal of Andrology 2007年第1期9卷 134-141页

作者： Frank Sommer Theodor Klotz Udo engelmann Department of Men＇s Health University Medical Center Hamburg-Eppendorf Hamburg 20214 Germany Department of Urology University Medical Center Hamburg-Eppendorf Hamburg 20214 Germany Department of Urology Klinikum Weiden Weiden 92637 Germany Department of Urology University of Cologne Cologne 50924 Germany

Aim： To test the hypothesis that sildenafil （50 mg nightly for one year） can improve spontaneous erectile function （EF） in men with mild-to-moderate arteriogenic erectile dysfunction （ED） responsive to erectogenic treatment. Methods： In a prospective open-label trial, 112 men with ED were randomized to sildenafil 50 mg nightly or sildenafil 50 or 100 mg as needed for 12 months, followed by one-month and 6-month non-medicated periods. Non-randomized, non-medicated men with ED were also assessed. The EF domain of the International Index of Erectile Function （IIEF EF） and the peak systolic velocity （PSV） of penile cavernous arteries were used to measure the efficacy. results： After sildenafil treatment and a subsequent non-medicated month, IIEF EF was normal in 29 of 48 （60.4%, 95% confidence interval [CI]： 45.3-74.2%） of the nightly group vs. 4 of 49 （8.2%, 95% CI： 2.3-19.6%） of the as-needed group. PSV improved by 11.2 cm/s （95% CI： 4.7-21.4; P = 0.012） in the nightly group but only by 3.4 cm/s （-5.1- 14.7; P = 0.435） in the as-needed group. IIEF EF normalized in 1 of 18 （5.6%, 95% CI： 0.1-27.3%） non-medicated men and the PSV declined slightly. Six months after treatment, the IIEF EF remained normal and PSV was stabilized in most （28/29, 97%） nightly group men who had initially normalized. Conclusion： Sildenafil nightly for one year resulted in ED regression that persisted well beyond the end of treatment, so that spontaneous EF was characterized as normal on the IIEF in most men. The results from this open-label, randomized trial warrant verification under double-blind, placebo-controlled conditions.

关键词： phosphodiesterase sexual dysfunctions psychological sildenafil citrate erectile funcion

role of nuclear factor kappa B in central nervous system regeneration

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Neural regeneration research 2014年第7期9卷 707-711页

作者： Christian engelmann Falk Weih ronny Haenold Leibniz Institute for Age research-Fritz Lipmann Institute

Activation of nuclear factor kappa B （NF-κB） is a hallmark of various central nervous system （CNS） pathologies. Neuron-specific inhibition of its transcriptional activator subunit relA, also referred to as p65, promotes neuronal survival under a range of conditions, i.e., for ischemic or excitotoxic insults. In macro- and microglial cells, post-lesional activation of NF-κB triggers a growth-permissive program which contributes to neural tissue inflammation, scar formation, and the expression of axonal growth inhibitors. Intriguingly, inhibition of such inducible NF-~B in the neuro-glial compartment, i.e., by genetic ablation of relA or overexpression of a trans- dominant negative mutant of its upstream regulator IκBa, significantly enhances functional recovery and promotes axonal regeneration in the mature CNS. By contrast, depletion of the NF-κB subunit p50, which lacks transcriptional activator function and acts as a transcriptional repressor on its own, causes precocious neuronal loss and exacerbates axonal degeneration in the lesioned brain. Collectively, the data imply that NF-κB orchestrates a multicellular pro- gram in which κB-dependent gene expression establishes a growth-repulsive terrain within the post-lesioned brain that limits structural regeneration of neuronal circuits. Considering these subunit-specific functions, interference with the NF-κB pathway might hold clinical potentials to improve functional restoration following traumatic CNS injury.

关键词： nuclear factor kappa B relA p65 p50 central nervous system injury axonal regeneration neural regeneration

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Cautious *** Little Threat From Euro

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当代外语研究 1999年第1期 15-16页

作者： Knut engelmann 沈默

欧元伴随1999年新年钟声而诞生。她在世界各地的国际外汇交易市场的亮相的消息成为新闻传媒的一个亮点。1999年1月4日上海一家大报的头条新闻是:上海金融界“欧元总动员”。打开1999年1月5日清晨的Internet,首先映入眼帘的消息是:欧元... 详细信息

欧元伴随1999年新年钟声而诞生。她在世界各地的国际外汇交易市场的亮相的消息成为新闻传媒的一个亮点。1999年1月4日上海一家大报的头条新闻是:上海金融界“欧元总动员”。打开1999年1月5日清晨的Internet,首先映入眼帘的消息是:欧元闪亮登场,美元不见惊慌。这篇文章写得精彩,信息丰富。美元,在本文称为“the worl’s most sought-after reserve currency”,对于欧元的面世,自然别有一番滋味在心头。这种微妙的心情在本文表现得淋漓尽致。当然,在种种复杂的情绪中,文章披露的两条倒也不无道理: 1....Europe might turn its back on(不理睬)Problems elsewhere in theworld economy as it concentrates on making its unprecedented currency unionwork. 2....the focus on the euro must not deflect(使偏斜)from structuralreforms to reduce sky-high unemployment rates m much of Europe. 美国人的担心(The euro will start to challenge the dollar as the world’slead currency)是否会成为现实,何时会成为现实。国人尚须拭目以待。现在就下结论,未免为时过早。此外,本文有几处措辞极为成功,读者不妨细读慢赏。】

关键词： Cautious U.S.Sees Little Threat From Euro

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Addressing the Negative Self-Concept in Posttraumatic Stress Disorder by a Three-Session Programme of Cognitive restructuring and Imagery Modification (CrIM-PTSD): A Case Study

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Journal of Behavioral and Brain Science 2018年第5期8卷 319-327页

作者： Meike Müller.engelmann Kerstin Hadouch regina Steil Department of Clinical Psychology and Psychotherapy Institute of Psychology Goethe University Frankfurt Main Frankfurt/Main Germany

Background: Cognitive restructuring and imagery modification for posttraumatic stress disorder (CrIM-PTSD) is a new intervention that involves only three sessions and focuses on the self-concept. It combines cognitive restructuring of core trauma-related dysfunctional beliefs and mental imagery. The effectiveness of CrIM-PTSD has recently been demonstrated in a pilot study. Method: This article presents a step-by-step description of the administration of CrIM-PTSD in a female survivor of childhood sexual abuse (CSA) suffering from PTSD and major depressive disorder related to strong self-blame. results: The intervention showed substantial reductions in PTSD symptoms and depression in the patient comparable to those observed in the pilot study. Conclusions: CrIM-PTSD might provide an economical tool for reducing PTSD symptoms when only a short time is available for intervention. Furthermore, this tool could be included in well-established PTSD treatments. In addition to the pilot study, a randomized controlled trial is needed to further explore the feasibility and effectiveness of this short intervention.

关键词： Posttraumatic Stress Disorder Cognitive restructuring Imagery Self-Concept