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Acetabular cup size trends in total hip arthroplasty

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World Journal of Orthopedics 2024年第1期15卷 39-44页

作者： Daniel Patrick McKenna Alex Price Timothy McAleese Darren Dahly Paul McKenna may cleary Department of Trauma and Orthopaedics University Hospital WaterfordWaterford X91 ER8EIreland Department of Epidemiology and Public Health University College CorkCork T12 XF62Ireland

BAcKGrOUND Total hip arthroplasty(THA)is a common procedure for end stage *** learning curve for THA is complex and *** of the most difficult skills to master is acetabular *** wish to identify if experience in arthroplasty leads to preservation of more bone *** To investigate if increasing surgeon experience will predict an ever decreasing acetabular cup *** A retrospective case series of four attending orthopaedic surgeons was *** uncemented elective total hip arthroplasties since appointment were selected for *** size of acetabular cup used was noted and logistic regression was used to identify if a trend to smaller cups *** A total of 1614 subjects were included with a mean age of 64 *** cups were on average 0.18mm smaller per year(95%confidence interval-0.25 to-0.11,Prgeon trends showed cup sizes to decrease 0.27 mm/year for surgeon A,0.02 mm/year for surgeon B,0.15 mm/year for surgeon c and 0.29 mm/year for surgeon *** of the four surgeons had a more pronounced trend to smaller cups for male subjects than their female *** We found increasing surgeon experience to be associated with an ever-decreasing acetabular cup *** acetabular cup size may act as a surrogate marker of surgical proficiency by virtue of decreased acetabular reaming.

关键词： Hip Arthroplasty Acetabulum cup Learning

cannabinoids and endocannabinoids as therapeutics for nervous system disorders:preclinical models and clinical studies

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Neural regeneration research 2024年第4期19卷 788-799页

作者： r.Scott Duncan Sean M.riordan Matthew c.Gernon Peter Koulen Department of Ophthalmology School of MedicineUniversity of Missouri Department of Biomedical Sciences School of MedicineUniversity of Missouri

cannabinoids are lipophilic substances derived from cannabis sativa that can exert a variety of effects in the human *** have been studied in cellular and animal models as well as in human clinical trials for their therapeutic benefits in several human *** of these include central nervous system(cNS)diseases and dysfunctions such as forms of epilepsy,multiple sclerosis,Parkinson’s disease,pain and neuropsychiatric *** addition,the endogenously produced cannabinoid lipids,endocannabinoids,are critical for normal cNS function,and if controlled or modified,may represent an additional therapeutic avenue for cNS *** review discusses in vitro cellular,ex vivo tissue and in vivo animal model studies on cannabinoids and their utility as therapeutics in multiple cNS *** addition,the review provides an overview on the use of cannabinoids in human clinical trials for a variety of cNS *** and endocannabinoids hold promise for use as disease modifiers and therapeutic agents for the prevention or treatment of neurodegenerative diseases and neurological disorders.

关键词： anandamide cannabidiol cannabinoid endocannabinoid epilepsy multiple sclerosis neurodegeneration neuroprotection tetrahydrocannabinol

Summarizing the evidence for robotic-assisted bladder neck reconstruction: Systematic review of patency and incontinence outcomes

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Asian Journal of Urology 2024年第3期11卷 341-347页

作者： Tenny r.Zhang Ashley Alford Lee c.Zhao Department of Urology NewYork-Presbyterian Hospital/Weill Cornell MedicineNew YorkNYUSA Department of Urology NYU Langone Medical CenterNew YorkNYUSA

Objective:Bladder neck contracture and vesicourethral anastomotic stenosis are difficult to manage endoscopically,and open repair is associated with high rates of *** recent years,there have been increasing reports of robotic-assisted bladder neck reconstruction in the ***,existing studies are small,heterogeneous case *** objective of this study was to perform a systematic review of robotic-assisted bladder neck reconstruction to better evaluate patency and incontinence ***:We performed a systematic review of PubMed from first available date to may 2023 for all studies evaluating robotic-assisted reconstructive surgery of the bladder neck in adult *** in non-English,author replies,editorials,pediatric-based studies,and reviews were *** of interest were patency and incontinence rates,which were pooled when ***:After identifying 158 articles on initial search,we included only ten studies that fit all aforementioned criteria for robotic-assisted bladder neck *** were case series published from March 2018 to March 2022 ranging from six to 32 men,with the median follow-up of 5e23 months.A total of 119 patients were included in our analysis.A variety of etiologies and surgical techniques were *** rates ranged from 50%to 100%,and pooled patency was 80%(95/119).De novo incontinence rates ranged from 0%to 33%,and pooled incontinence was 17%(8/47).Our findings were limited by small sample sizes,relatively short follow-ups,and heterogeneity between studies.

关键词： Bladder neck continence Incontinence Patency Posterior urethra reconstructive surgery robotic surgery Stenosis Stricture Surgical outcome

Adherence to Advisory committee on Immunization Practices in diabetes mellitus patients in Saudi Arabia:A multicenter retrospective study

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World Journal of Diabetes 2024年第3期15卷 440-454页

作者： Saleh Fahad Alqifari Aya K Esmail Dalal M Alarifi Ghalya Y Alsuliman Maram M Alhati may r Mutlaq Mohammed Aldhaeefi Shaden A Alshuaibi Palanisamy Amirthalingam Abrar Abdallah Afaf S Wasel Heba r Hamad Shoroq Alamin Tasneem H Atia Tariq Alqahtani Department of Pharmacy Practice University of TabukTabuk 71491Saudi Arabia Department of clinical Sciences Sulaiman Alrajhi UniversityQassim 52726Saudi Arabia Department of Family Medicine International Medical CenterJeddah 23214Saudi Arabia clinical and Administrative Pharmacy Sciences College of PharmacyHoward UniversityWashingtonDC 20059United States Department of Pharmacology King Saud Bin Abdulaziz University for Health SciencesKing Abdullah International Medical Research CenterRiyadh 11481Saudi Arabia

BAcKGrOUND Patients with diabetes mellitus(DM)are predisposed to an increased risk of infection signifying the importance of vaccination to protect against its potentially severe *** centers for Disease control and Prevention/Advisory committee on Immunization Practices(cDc/AcIP)issued immunization recommendations to protect this patient *** To assess the adherence of patients with DM to the cDc/AcIP immunization recommendations in Saudi Arabia and to identify the factors associated with the vaccine adherence *** An observational retrospective study conducted in 2023 was used to collect data on the vaccination records from 13 diabetes care centers in Saudi Arabia with 1000 eligible patients in phase I with data collected through chart review and 709 patients in phase II through online *** Among participants,10.01%(n=71)had never received any vaccine,while 85.89%(n=609)received at least one dose of the coronavirus disease 2019(cOVID-19)vaccine,and 34.83%(n=247)had received the annual influenza *** 2.96%(n=21),2.11%(n=15),and 1.12%(n=8)received herpes zoster,tetanus,diphtheria,and pertussis(Tdap),and human papillomavirus(HPV)vaccines,*** patients with DM in Saudi Arabia,the rate of vaccination for annual influenza and cOVID-19 vaccines was higher compared to other vaccinations such as herpes zoster,Tdap,pneumococcal,and *** such as vaccine recommendations provided by family physicians or specialists,site of care,income level,DM-related hospitalization history,residency site,hemoglobin A1c(HbA1c)level,and health sector type can significantly influence the vaccination rate in patients with *** non-vaccinated patients with DM,the most reported barriers were lack of knowledge and fear of side *** signifies the need for large-scale research in this area to identify additional factors that might facilitate adherence to cDc/AcIP vaccine recommendations in patients with *** In S

关键词： Diabetes mellitus Vaccine recommendation cOVID-19 vaccine Influenza vaccine Pneumococcal vaccine Immunization retrospective study

Efficacy of nonsolvent flower pollen extracts in healthy women with urinary incontinence:A randomized,double-blind,placebo-controlled,parallel study

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current Urology 2024年第3期18卷 203-211页

作者： Marc Moulin Erin D.Lewis David c.crowley colleen E.may Malkanthi Evans KGK Science Inc. LondonOntarioCanada Graminex L.L.C.SaginawMIUSA

Background Urinary incontinence(UI)is a debilitating and common condition that adversely affects quality of *** and surgical approaches for managing UI symptoms may result in undesirable risks and *** randomized,double-blind,placebo-controlled,parallel study investigated the efficacy of 2 nonsolvent flower pollen extracts on UI in healthy *** and methods One-hundred and fourteen women aged 40–75 years who scored≥5 on the International consultation on Incontinence Questionnaire-Urinary Incontinence Short Form(IcIQ-SF)were randomized to receive either Graminex®rcT Fem™UI,Graminex®PollenBerry®,or placebo for 24 *** primary outcome was the change in the IcIQ-SF score between the trial and placebo groups after 24 weeks of *** secondary outcomes included changes in the frequency of nocturia(recorded in 3-day void diaries)and 24-hour leakage volume(assessed via pad weight)after 6,12,18,and 24 weeks of supplementation and changes in stress-induced urinary leakage volume(after completion of a provocative maneuver challenge)after 24 weeks of *** All the groups demonstrated improvement in IcIQ-SF scores at week 24(prcT Fem™UI group had the greatest improvement in IcIQ-SF scores(−4.07±3.4),followed by the PollenBerry®group(−3.34±2.87)and placebo group(−2.61±3.52).The rcT Fem™UI group had corresponding improvements in 24-hour leakage volume(−17.68±39.84 g)and frequency of nocturia(−0.52±1.26)(p≤0.05).PollenBerry®supplementation significantly improved stress-induced urinary leakage volume(−7.12±15.64 g)at week *** study products demonstrated safe hematological and chemical *** rcT Fem™UI supplementation resulted in significant and clinically meaningful reductions in UI severity,with corresponding improvements in daily urinary leakage volume and frequency of ***®significantly improved stress-induced urinary leakage volume,suggesting that it may be eff

关键词： Urinary incontinence Pollen extract Healthy women Dietary supplement IcIQ-SF Urinary leakage

Prediction and control of cholera outbreak:Study case of

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Infectious Disease Modelling 2024年第3期9卷 892-925页

作者： c.Hameni Nkwayep r.GlèlèKakaï S.Bowong Laboratory of Mathematics Department of Mathematics and Computer ScienceUniversity of DoualaPO Box 24157DoualaCameroon IrD Sorbonne UniversityUMMISCOF-93143BondyFrance Biomathematics and Forest Modeling University of Abomey-CalaviCalaviBenin

This paper deals with the problem of the prediction and control of cholera outbreak using real data of *** first develop and analyze a deterministic model with seasonality for the cholera,the novelty of which lies in the incorporation of undetected *** present the basic properties of the model and compute two explicit threshold parametersr_(0)and r_(0).that bound the effective reproduction number,from below and above,that is r_(0)≤r_(0)≤r_(0).We prove that cholera tends to disappear whenr_(0)≤1,while when r_(0)>1,cholera persists uniformly within the ***,assuming that the cholera transmission rates and the proportions of newly symptomatic are unknown,we develop the EnKf approach to estimate unmeasurable state variables and these unknown parameters using real data of cholera from 2014 to 2022 in *** use this result to estimate the upper and lower bound of the effective reproduction number and reconstructed active asymptomatic and symptomatic cholera cases in cameroon,and give a short-term forecasts of cholera in cameroon until *** simulations show that(i)the transmission rate from free Vibrio cholerae in the environment is more important than the human transmission and begin to be high few week after may and in October,(ii)90%of newly cholera infected cases that present the symptoms of cholera are not diagnosed and(iii)60.36%of asymptomatic are detected at 14%and 86%of them recover *** future trends reveals that an outbreak appeared from July to November 2023 with the number of cases reported monthly peaked in October *** impulsive control strategy is incorporated in the model with the aim to avoid or prevent the cholera *** the first year of monitoring,we observed a reduction of more than 75%of incidences and the disappearance of the peaks when no control are available in cameroon.A second monitoring of control led to a further reduction of around 60%of incidences the following year,showing how

关键词： Vibrio cholerae Mathematical models Ensemble Kalman filterBasic reproduction number Impulsive control

Littoral landforms of Lake Hulun and Lake Buir(china and Mongolia):Wind-driven hydro-sedimentary dynamics and resulting clastics distribution

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Journal of Palaeogeography 2024年第2期13卷 309-326页

作者： Li Wang Mathieu Schuster Shi-Wei Xin Florin Zainescu Xin-Yu Xue Joep Storms Jan-Hendrik may Alexis Nutz Helena van der Vegt Guilherme Bozetti Zai-Xing Jiang School of Energy resources China University of Geosciences(Beijing)Beijing100083China Universite de Strasbourg CNRSENGEESInstitut Terre et Environnement de StrasbourgUMR 70635 Rue DescartesStrasbourgFrance Tamsag Mongolia(XIX)Ltd. PetroChinaDaqing 163000China cErEGE Aix-Marseille UniversitéCNESIRDCollege de FranceINRAAix en ProvenceFrance School of Marine Science Sun Yat-sen UniversityZhuhai 519083China Delft University of Technology Department of Geoscience and EngineeringDelfthe Netherlands School of Geography Earth and Atmospheric SciencesUniversity of Melbourne253 Elgin St.CarltonVIC 3053Australia Deltares Delfthe Netherlands ScMF Faculty of GeographyUniversity of Bucharest1 N.Balcescu Blv.BucharestRomania

Two rectangular-shaped lakes,Lake Hulun and Lake Buir,located at the boundary between china and Mongolia,only c.75 km apart and therefore experiencing similar wind fields,have been studied based on satellite images and field surveys in order to compare their geomorphological and sedimentological *** wind-driven hydrodynamics,which have a significant effect on the development of littoral landforms and on sediment distribution,have been discussed for the two similar lakes that experienced a prevailing wind perpendicular to their long axis.A conceptual model related to wind-driven water bodies and sediment distribution is ***-influenced to wave-dominated deltas,beaches,spits,and eolian dune deposits develop around these two lakes,with a strikingly similar distribution *** features locally inform the longshore drift and help reconstruct the water circulation induced by wind *** the NW prevailing wind regime,the spits developed on the SW coast with a NW—SE extension,which was influenced by the NW—SE longshore *** same influence was observed in the delta extension in the NE *** differences lie in the presence of fan deltas in the NW region of Lake Hulun,but not in Lake ***,the width of the beach and eolian deposits on the downwind coast of Lake Hulun is three times greater than that of Lake Buir which were caused by the differences in sediment supply and wind fetch between the two *** Hulun and Lake Buir provide two reliable examples to understand the relationship among the wind field,provenance,hydrodynamics,landforms,and asymmetrical distribution of clastics in elongated *** also represent relevant modern analogs,which may also be of guiding significance to wind-driven sand body prediction in lacustrine basins.

关键词： Wind-driven lakes Fetch Sedimentary facies Hydrodynamics Geomorphology Spits Shoreline Lake Hulun Lake Buir

观察对比乳腺X线片的变化对大样本社区人群乳腺X线筛检效果的影响

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国际医学放射学杂志 2012年第1期 81-81页

作者： B.c.Yankaskas r.c.may J.Matuszewski J.M.Bowling M.P.Jarman B.F.Schroeder 夏艺 carolina Mammography registry Department of RadiologyUniversity of North Carolina School of MedicineMason Farm RdCB 7515Chapel HillNC 27599-7515

目的评价对比乳腺X线片对乳腺X线筛检准确率、敏感度、特异度、阳性预测值(PPV1)及癌症检出率(cDr)的影响,判定识别对比乳腺X线片变化的作用。材料与方法此前瞻性研究符合HIPAA,经机构审查委员会批准,无需病

关键词：乳腺癌症乳房筛检

Large dinosaur egg accumulations and their significance for understanding nesting behaviour

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Geoscience Frontiers 2024年第5期15卷 467-488页

作者： L.Ezquerro r.coimbra B.Bauluz c.Núñez-Lahuerta T.román-Berdiel M.Moreno-Azanza Departamento de Geodinámica Estratigrafía y PaleontologíaFacultad de Ciencias GeológicasUniversidad Complutense de MadridC/JoséAntonio Novais1228040MadridSpain Aragosaurus-IUcA:recursos Geológicos y Paleoambientales.Departamento de ciencias de la Tierra.Facultad de ciencias Universidad de ZaragozaC/Pedro Cerbuna 1250009 ZaragozaSpain Museu da Lourinha LourinhaPortugal GeoBioTec Department of Earth SciencesNOVA School of Science and TechnologyUniversidade Nova de LisboaCaparicaPortugal GeoBioTec Departamento de GeocienciasUniversidade de AveiroAveiroPortugal Insitut catalàde Paleoecologia Humana i EvolucióSocial(IPHES-cErcA) Zona Educacional 4Campus Sescelades URV(Edifici W3)43007 TarragonaSpain Departament d´Història i Història de l´Art Universitat Rovira i VirgiliAv.Catalunya 3543002 TarragonaSpain Geotransfer IUcA Departamento de Ciencias de La TierraFacultad de CienciasUniversidad de ZaragozaZaragozaSpain

The accurate identification of dinosaur egg accumulations as nests or clutches is crucial for understanding the reproductive behaviour of these extinct ***,existing methods often rely on the presence of complete eggs and embryo remains,and sedimentological criteria that are only applicable to well-structured *** this study,we introduce an innovative approach to characterize egg accumulations in structureless sediments,where traditional nest structures may not be *** methodology employs a unique combination of sedimentological,taphonomic,geochemical,and geophysical proxies for the study of egg *** applied this approach to the egg accumulation from Paimogo(Jurassic,Portugal),traditionally interpreted as a *** findings reveal that the Paimogo egg assemblage is a secondary deposit,resulting from a flooding event in a fluvial plain that dismantled several allosauroid and crocodylomorph *** eggshell vapor conductance results,coupled with sedimentological evidence,suggest that allosauroid dinosaurs buried their eggs in the dry terrain of overbank areas close to a main channel during the breeding season,likely during the dry season to prevent the embryos from *** research underscores the necessity of multidisciplinary approaches in interpreting egg accumulations and offers a novel methodology for studying these accumulations in structureless *** findings provide new insights into the breeding behaviour and nesting preferences of these extinct organisms,contributing to our understanding of dinosaur ecology.

关键词： Breeding behaviour Theropod Taphonomy Stable isotopes Magnetic susceptibility Jurassic