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AnALYSIS OF nAnOBrIDGE TESTS

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Acta Mechanica Solida Sinica 2010年第4期23卷 283-296页

作者： Wing Kin Chan Jianrong Li Yong Wang Shengyao Zhang Tongyi Zhang (Department of Mechanical Engineering, Hong Kong University of Science and Technology, Clear Water.bay, Kowloon, Hong Kong, China) Department of Mechanical Engineering Hong Kong University of Science and Technology Kowloon Hong Kong China

This paper analyzes nanobridge tests with consideration of adhesive contact deformation, which occurs between a probe tip and a tested nanobeam, and deformation of a substrate or template that supports the tested *** displacement-load relation, including adhesive contact deformation and substrate deformation, is presented here for small deformation of *** analytic results are confirmed by finite element *** adhesive contact deformation and substrate deformation are not considered in the analysis of nanobridge test data, they might lead to lower values of Young＇s modulus of tested nanobeams.

关键词： nanobridge tests size-dependency adhesion contact compliance surface effect substrate effect finite element

The metabolite, alpha-ketoglutarate inhibits non-alcoholic fatty liver disease progression by targeting lipid metabolism

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Liver research 2020年第2期4卷 94-100页

作者： Katsuya nagaoka Joud Mulla Kevin Cao Zhixiang Cheng Dan Liu William Mueller Amalia bay Grace Hildebrand Shaolei Lu Chiung-Kuei Huang Liver research Center Division of Gastroenterology&Liver Research CenterWarren Alpert Medical School of Brown University and Rhode Island HospitalProvidenceRIUSA Department of Pathology and Laboratory Medicine Warren Alpert Medical School of Brown UniversityRhode Island HospitalProvidenceRIUSA

Background:non-alcoholic liver disease is of increased concern and contributing to economic burdens not only in developing countries but in developed countries as *** the biomarker of early diagnosis and early intervention approaches for non-alcoholic liver disease is unmet and required further *** the alpha-ketoglutarate(a-KG)is recently proposed to be a potential biomarker in differentiating patients with obesity from those with non-alcoholic liver disease,how a-ketoglutatate is involved in the fatty liver progression is not ***:A high-fat diet(HFD)feeding animal model,liver functional assays,and molecular approaches were adopted to clarify the impact of a-KG in fatty liver ***:In the current study,it was found that dietary a-KG would inhibit weight gain in male and female mice fed with a normal chew or *** feeding caused fatty liver in male mice,but a-KG treatment could substantially inhibit hepatic steatosis *** studies revealed the possible linkage of a-KG protective functions to lipid *** analysis identified the important role of peroxisome proliferator-activated receptors in beneficial a-KG-mediated effects on fatty liver ***:The current study demonstrates the therapeutic potential of a-KG and how it may be used,via dietary supplementation,as a preventive intervention for non-alcoholic liver disease in obese patients.

关键词： Peroxisome proliferator-activated receptor gamma(PPArγ) Steatosis non-alcoholic fatty liver disease(nAFLD) non-alcoholic steatohepatitis(nASH) Alpha-ketoglutarate(a-KG) Gender difference C57BL/6 mouse

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经营者指引

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青年男性病人的腹股沟疝修补:用补片还是单纯缝合?

1984年

作者： Timothy bay 王孔正译

来源：汇雅图书（南通市图书馆... 评论

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中国实用外科杂志 2011年第8期31卷 752-755页

作者： Bisgaard T bay-nielsen M Kehlet H Department of Surgery KΦge SygehusKΦgeDen-mark Department of Surgical Gastroenterology Hvidovre University HospitalHvidovreDenmark Section for Surgical Pathophysiology 4074Rigshospitalet Copenhagen UniversityCopenhagenDen-mark

目的目前还没有治疗青年男性腹股沟疝病人的最佳修补方法的大宗病例报道。该文分析了丹麦全国青年男性病人接受Lichtenstein术或传统非补片修补术后复发再手术的风险。方法在丹麦国家疝数据库内前瞻性地记录了1998-01-01至2005-12-31所... 详细信息

目的目前还没有治疗青年男性腹股沟疝病人的最佳修补方法的大宗病例报道。该文分析了丹麦全国青年男性病人接受Lichtenstein术或传统非补片修补术后复发再手术的风险。方法在丹麦国家疝数据库内前瞻性地记录了1998-01-01至2005-12-31所有接受手术治疗的腹股沟疝病例,以复发再次接受手术作为判定复发的标准。该研究的入组标准为数据库中年龄在18～30岁之间的原发性腹股沟斜疝并在研究阶段内接受了第一次修补手术的病例。结果在纳入该研究的3181例病人中,1120例(中位年龄23岁,范围18～30岁)接受了单纯的缝合修补术,2061例(中位年龄24岁,范围18～30岁)接受了Lichtenstein术。单纯缝合组的中位随访时间为62(0～96)个月,Lichtenstein组的中位随访时间为41(0～96)个月。两组的5年累积复发再手术率分别为1.6%(Lichtenstein组)和3.9%(单纯缝合组),单纯缝合组的术后总复发再手术率(39例,3.5%)为Lichtenstein组(24例,1.2%)的将近3倍(P=0.003)。结论与传统单纯缝合修补术相比,在18～30岁的青年腹股沟斜疝病人中应用Lichtenstein术可以大大降低术后复发的风险。但是,在治疗青年男性病人中应用补片时必须衡量术后可能发生的慢性疼痛的风险。

关键词：疝复发青年修补术

Boron Isotopic Fractionation and Trace Element Incorporation in Various Species of Modern Corals in Sanya bay, South China Sea

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Journal of Earth Science 2014年第3期25卷 431-444页

作者： Haizhen Wei Shaoyong Jiang Yingkai Xiao n Gary Hemming State Key Laboratory for Mineral Deposits research Department of Earth Sciences Nanjing University State Key Laboratory of Geological Processes and Mineral resources Faculty of Earth ResourcesChina University of Geosciences Wuhan Qinghai Institute of Salt Lakes Chinese Academy of Sciences Lamont-Doherty Earth Observatory of Columbia University Queens College School of Earth and Environmental Sciences

The boron isotope paleo-pH proxy has been extensively studied due to its potential for understanding past climate change, and further calibrations were considered for accurate applications of the proxy because of significant variability related to biocarbonate microstructure. In this work, we studied the boron isotopic fractionation between modern marine corals and their coexisting seawater collected along shallow area in Sanya bay, South China Sea. The apparent partition coefficient of boron（KD） ranged from 0.83×10-3 to 1.69×10-3, which are in good agreement with previous studies. As the analyzed coral skeleton（~5 g） spanned the growth time period of 1–2 years, we discussed the boron isotopic fractionation between pristine corals and modern seawater using the annual mean seawater pH of 8.12 in this sea area. Without taking the vital effect into account,（11B/10B）coral values of all living corals spread over the curves of（11B/10B）borate vs.（11B/10B）sw with the α4-3 values ranging from 0.974 to 0.982. After calibrating the biological effect on the calcifying fluid pH, the field-based calcification on calcifying fluid pH（i.e., Δ（pHbiol-pHsw）） for coral species of Acropora, Pavona, Pocillopora, Faviidae, and others including Proites are 0.42, 0.33, 0.36, 0.19, respectively, and it is necessary to be validated by coral culturing experiment in the future. Correlations in B/Ca vs. Sr/Ca and B/Ca vs. pHbiol approve temperature and calcifying fluid pH influence on skeletal B/Ca. Fundamental understanding of the thermodynamic basis of the boron isotopes in marine carbonates and seawater will strengthen the confidence in the use of paleo-pH proxy as a powerful tool to monitor atmospheric CO2 variations in the past.

关键词： boron isotope paleo-pH proxy boron isotopic fractionation trace element modern coral.

THE MArInE ECO TYPE OF SOTALIA FLUVIATILIS （CETACEA: DELPHInIDAE） In MAnZAnILLO bay, PArIA PEnInSULA, VEnEZUELA

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THE MARINE ECO TYPE OF SOTALIA FLUVIATILIS （CETACEA: DELPHI...

Synthesis and optical limiting in copolymers of C_(60) and 1-phenyl-1-butyne

第十九届国际动物学大会

作者： L.Oviedo r.Acevedo n.Silva Working Group Proyecto Golfo de la Ballena Biotropica: Center for Research and Conservation of Tropical Biodiversity. Caracas Venezuela Working Group Proyecto Golfo de la Ballena Biotropica: Center for Research and Conservation of Tropical Biodiversity. Caracas Venezuela Peking University China Working Group Proyecto Golfo de la Ballena Biotropica: Center for Research and Conservation of Tropical Biodiversity. Caracas Venezuela

＜正＞Sotalia fluviatilis is referenced as a continental marine mammal among with Inia geoffrensis, by its occurrence in major inland water bodies as the Orinoco and Maracaibo Lake. In a recent study based on coastal communities’ knowledge, tu-cuxi prevailed as the dominant dolphin species in the Paria Gulf. Manzanillo bay is compound by 5 coves within a military protected area, where wilderness remains intact. The aim of this investigation is to document by preliminary observations the habitat use and behavioral patterns of a potential resident population of S . fluviatilis in the Paria Peninsula. Cetacean surveys were carried out using land based platforms. Three different observation points were identified and used, the geographical location of these observation points allowed a view field that covers both the east coves and the west ones. Three observers participate in dolphin watching sessions, equipped with Tasco 10×50 wide angle binoculars each, 6 hours of sunlight were spent in the survey at Beauford sea state of 2. Preliminary ethological data were gathered through ad libitum sampling. A group of twenty individuals of Sotalia fluviatilis including two calves were sighted during the survey. nine different behaviors were recorded: front roll, tail slapping, front leap, spy hopping, traveling, logging, diving, speed burst, and feeding splash. Behavior patterns differed depending on the Cove where they fed. There are clear evidences of non-homogeneous habitat utilization, strongly associates with prey distribution. Sotalia in Manzanillo bay might be a relict population that requires conservation measurements.

关键词： Tucuxi Feeding behavior habitat use Military protected area

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Chinese Chemical Letters 2000年第1期11卷 21-22页

作者： Hong Yao XU Shan Yi GUAnG Ben Zhong TAnG (Department of Chemistry, Anhui University, Hefei 230039 Department of Chemistry, Hong Kong University of Science & Technology, Clear Water.bay, Kowloon, Hong Kong) Department of Chemistry Anhui University Hefei 230039 China Department of Chemistry Hong Kong Univ. of Sci. and Technol. Clear Water Bay Kowloon Hong Kong

While WC_16-Ph_4Sn is a poor catalyst for the polymerization of l-phenyl-butyne (PB) at room temperature, it effectively polymerizes PB in the presence of C_(60), giving high molecular weight polymers in high yields. The polymer is soluble in THF and chloroform and spectroscopic analysis reveals that Coo has copolymerized with PB. Thus, C_(60) plays dual roles of comonomer and cocatalyst in the acetylene polymerization. The copolymers strongly attenuate 532-nm laser pulses, whose limiting performance is superior to that of parent C_(60)

关键词： C_(60) polyacetylene fullerene polymer.

Treatment of Budd-Chiari syndrome with a focus on transjugular intrahepatic portosystemic shunt

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World Journal of Hepatology 2013年第1期5卷 38-42页

作者： Anders bay neumann Stine Degn Andersen Dennis Tφnner nielsen Peter Holland-Fischer Hendrik Vilstrup Henning Grφnbk Department of Medicine V (Gastroenterology and Hepatology) Aarhus University HospitalDK-8000 Aarhus CDenmark Department of radiology r Aarhus University HospitalDK-8000 Aarhus CDenmark

AIM:To evaluate long-term complications and survival in patients with Budd-Chiari syndrome (BCS) referred to a Danish transjugular intrahepatic portosystemic shunt (TIPS) ***:Twenty-one consecutive patients from 1997-2008 were retrospectively included [15 women and 6 men,median age 40 years (range 17-66 years)].Eighteen Danish patients came from the 1.8 million catchment population of Aarhus University Hospital and three patients were referred from Scandinavian *** consisted of tests for underlying haematological,endocrinological,or hypercoagulative disorders parallel to initiation of specific treatment of ***:BCS was mainly caused by thrombophilic (33%) or myeloproliferative (19%) *** percents had symptoms for less than one week with ascites as the most prevalent *** (67%) were treated with TIPS and 7 (33%) were manageable with treatment of the underlying condition and *** median follow-up time for the TIPS-treated patients was 50 mo (range 15-117 mo),and none required subsequent liver *** control was achieved in all TIPS patients with a marked reduction in the dose of diuretics.A total of 14 TIPS revisions were needed,mostly of uncovered *** died during follow-up:One non-TIPS patient worsened after 6 mo and died in relation to transplantation,and one TIPS patient died 4 years after the TIPS-procedure,unrelated to ***:In our BCS cohort TIPS-treated patients have near-complete survival,reduced need for diuretics and compared to historical data a reduced need for liver transplantation.

关键词： Ascites Budd-Chiari syndrome Myeloproliferative disorder Thrombophilia Thrombosis Transjugular intrahepatic portosystemic shunt

莫桑比克天然气行业动态与经济增长的影响研究

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莫桑比克天然气行业动态与经济增长的影响研究

作者： Abdul Gafur nazordine Mahomed bay 江西财经大学

学位级别：硕士

在莫桑比克,天然气首次大规模商业化生产是在2004年。近期,罗瓦马盆地天然气的发现,使得莫桑比克成为世界天然气储量最高的十大国家之一。莫桑比克人对此表现出高度的期待,因为这将有助于莫桑比克的社会经济发展,缓解莫桑比克的经济困难... 详细信息

在莫桑比克,天然气首次大规模商业化生产是在2004年。近期,罗瓦马盆地天然气的发现,使得莫桑比克成为世界天然气储量最高的十大国家之一。莫桑比克人对此表现出高度的期待,因为这将有助于莫桑比克的社会经济发展,缓解莫桑比克的经济困难,从而提高人民的生活水平。人们对天然气的使用增多,得益于它可以減少二氧化碳排放量和其他污染物,这也符合对温室气体排放的限制政策。本研究调查了1999年至2015年期间天然气工业的动态和莫桑比克的经济增长。数据来自世界银行编制的索引孟迪。本文采用Eviews 7.2软件进行误差校正模型分析。分析显示,从长期来看,天然气工业、出口、劳务与经济增长正相关。在短期的关系中,天然气行业对经济增长有着重要的积极影响,而出口和劳动力则对经济增长的影响较小。同时,研究发现,在另一方面,出口和劳务也会相互影响:出口增加导致对整体劳务的增加,反之亦然。这些结果的含义是,政府应该实施天然气行业的增长政策,因为这将刺激经济增长,而经济增长又会促进出口,在国内创造更多的就业机会。在莫桑比克,天然气行业将在2022年开始在罗瓦马盆地生产天然气的过程中发生巨大变化,并将对未来的莫桑比克经济增长起到重要作用。因此,政府在评估天然气行业时应该严格遵守透明度原则;不仅要确保这一自然资源能为经济增长作出重大贡献,而且要确保其勘探是可持续的。与天然气行业相关的招标、许可、谈判、签约,以及签订提取的数据、产品价格和所收取的收入的协议,在所有的评估阶段的程序都必须是透明的。因为它可以防止责任纠纷,从而防止发生內部冲突。对于莫桑比克天然气工业的发展,本文提出以下建议:(i)为天然气行业发展创造有利的环境,增强投资者的信心,包括減少监管障碍;(ii)促进当地中小企业参与罗瓦马盆地天然气项目开发,为他们获得商机创造条件;(iii)完善适用于莫桑比克天然气工业发展的法律和体制机制;(四)支持对可能的腐败行为实行零容忍政策;(五)按照环保规定,促进天然气的可持续勘探。这项研究填补了莫桑比克天然气行业动态和经济增长的文献空白。未来的研究应重点关注天然气的需求和供应、价格监管和利益相关者在罗瓦马盆地天然气项目中的作用。

关键词：天然气工业经济增长罗瓦马盆地天然气误差校正模型莫桑比克