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New insights on premature ejaculation： a review of ：lefinition, classification, prevalence and treatmeni

丛书名： PDQ series

2005年

作者： Cassileth Barrie r.

来源：畅想之星图书光盘版（南... 评论

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Asian Journal of Andrology 2012年第6期14卷 822-829页

作者： Ege C Serefoglu Theodore r Saitz Tulane University School of Medicine Department of Urology New Orleans LA 70112 USA

There are ongoing debates about the definition, classification and prevalence of premature ejaculation （PE）. The first evidence-based definition of PE was limited to heterosexual men with lifelong PE who engage in vaginal intercourse. Unfortunately, many patients with the complaint of PE do not meet these criteria. However, these men can be diagnosed as one of the PE subtypes, namely acquired PE, natural variable PE or premature-like ejaculatory dysfunction. Nevertheless, the validity of these subtypes has not yet been supported by evidence. The absence of a universally accepted PE definition and lack of standards for data acquisition have resulted in prevalence studies that have reported conflicting rates. The very high prevalence of 20%-30% is probably due to the vague terminology used in the definitions at the time when such surveys were conducted. Although many men may complain of PE when questioned for a population-based prevalence study, only a few of them will actively seek treatment for their complaint, even though most of these patients would define symptoms congruent with PE. The complaints of acquired PE patients may be more severe, whereas complaints of patients experiencing premature-like ejaculatory dysfunction seem to be least severe among men with various forms of PE. Although numerous treatment modalities have been proposed for management of PE, only antidepressants and topical anaesthetic creams have currently been proven to be effective. However, as none of the treatment modalities have been approved by the regulatory agencies, further studies must be carried to develop a beneficial treatment strategy for PE.

关键词： definition ejaculatory disorders epidemiology premature ejaculation sexual dysfunction treatment

Prediction of blast-induced flyrock in Indian limestone mines using neural networks

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Journal of rock Mechanics and Geotechnical Engineering 2014年第5期6卷 447-454页

作者： r.Trivedi T.N.Singh A.K.raina Central Institute of Mining and Fuel research Council of Scientific and Industrial Research (CSIR)DhanbadIndia Department of Earth Sciences Indian Institute of Technology BombayPowaiMumbai 400076India Central Institute of Mining and Fuel research Council of Scientific and Industrial Research (CSIR)Regional CentreNagpurIndia

Frequency and scale of the blasting events are increasing to boost limestone production. Mines areapproaching close to inhabited areas due to growing population and limited availability of land resourceswhich has challenged the management to go for safe blasts with special reference to opencast *** study aims to predict the distance covered by the flyrock induced by blasting using artificial neuralnetwork （ANN） and multi-variate regression analysis （MVrA） for better assessment. Blast design andgeotechnical parameters, such as linear charge concentration, burden, stemming length, specific charge,unconfined compressive strength （UCS）, and rock quality designation （rQD）, have been selected as inputparameters and flyrock distance used as output parameter. ANN has been trained using 95 datasets ofexperimental blasts conducted in 4 opencast limestone mines in India. Thirty datasets have been used fortesting and validation of trained neural network. Flyrock distances have been predicted by ANN, MVrA,as well as further calculated using motion analysis of flyrock projectiles and compared with the observeddata. Back propagation neural network （BPNN） has been proven to be a superior predictive tool whencompared with MVrA. 2014 Institute of rock and Soil Mechanics, Chinese Academy of Sciences. Production and hosting byElsevier B.V. All rights reserved.

关键词： Artificial neural network(ANN) Blasting Opencast mining Burden Stemming Specific charge Flyrock

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Author Guidelines

世界耳鼻咽喉头颈外科杂志(英文) 2023年第3期9卷 262-269页

作者： razavi, Christopher r. Wang, Tom Icahn Sch Med Mt Sinai Dept Otolaryngol Head & Neck Surg Div Facil Plast & Reconstruct Surg New York NY 10029 USA Oregon Hlth & Sci Univ Dept Otolaryngol Head & Neck Surg Div Facil Plast & Reconstruct Surg Portland OR 97201 USA

*** Thank you for your interest in World Journal of Otorhinolaryngology-Head&Neck Surgery(WJOHNS).Note that submission implies that the content has not been published or submitted for publication elsewhere except as a... 详细信息

关键词： implies content Surgery

3D random Voronoi grain-based models for simulation of brittle rock damage and fabric-guided micro-fracturing

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Journal of rock Mechanics and Geotechnical Engineering 2014年第6期6卷 506-521页

作者： E.Ghazvinian M.S.Diederichs r.Quey Geo Engineering Centre Queen's UniversityKingston ON Canada Ecole Nationale Supérieure des Mines de Saint-Etienne CNRS UMR 5307 France

A grain-based distinct element model featuring three-dimensional （3D） Voronoi tessellations （randompoly-crystals） is proposed for simulation of crack damage development in brittle rocks. The grainboundaries in poly-crystal structure produced by Voronoi tessellations can represent flaws in intact rockand allow for numerical replication of crack damage progression through initiation and propagation ofmicro-fractures along grain boundaries. The Voronoi modelling scheme has been used widely in the pastfor brittle fracture simulation of rock materials. However the difficulty of generating 3D Voronoi modelshas limited its application to two-dimensional （2D） codes. The proposed approach is implemented inNeper, an open-source engine for generation of 3D Voronoi grains, to generate block geometry files thatcan be read directly into 3DEC. A series of Unconfined Compressive Strength （UCS） tests are simulated in3DEC to verify the proposed methodology for 3D simulation of brittle fractures and to investigate therelationship between each micro-parameter and the model＇s macro-response. The possibility of numericalreplication of the classical U-shape strength curve for anisotropic rocks is also investigated innumerical UCS tests by using complex-shaped （elongated） grains that are cemented to one another alongtheir adjoining sides. A micro-parameter calibration procedure is established for 3D Voronoi models foraccurate replication of the mechanical behaviour of isotropic and anisotropic （containing a fabric） rocks. 2014 Institute of rock and Soil Mechanics, Chinese Academy of Sciences. Production and hosting byElsevier B.V. All rights reserved.

关键词： Numerical modelling 3D Voronoi tessellation Discrete element method Grain-based model Crack damage thresholds Fabric-guided micro-fracturing Anisotropy

SEMILEPTONIC BOTTOM HADrON DECAYS AND THE DETErMINATION OF Ycb AND Vub

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Chinese Physics C 2016年第10期40卷 770-784页

作者： r. Kowalewski T. Mannel Univ. of Victoria Canada Univ. of Siegen Germany

INTrODUCTION Precision determinations of ｜Vub｜ and ｜Vcb｜ are central to testing the CKM sector of the Standard Model, and complement the measurements of CP asymmetries in B decays. The length of the side of the unitarity triangle opposite the well-measured angle β is proportional to the ratio ｜ Vub｜/｜Ycb｜; its determination is a high priority of the heavy-flavor physics program.

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GENErATION AND MAINTENANCE OF A FIELD rEVErSED CONFIGUrATION BY MEANS OF A rOTATING MAGNETIC FIELD

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Chinese Physics Letters 1987年第10期4卷 461-464页

作者： A.Knight WU Cheng I.r.Jones School of Physical Sciences The Flinders University of South AustraliaBedford ParkS.A.5042

An experiment in which a rotating magnetic field was used to drive current in a cylindrical device was *** driven current was of sufficient size to reverse the applied axial *** an equilibrium could equally well be termed a field reversed configuration(FrC).In this experiment the FrC lifetime appeared to be limited by the duration of the rotating field pulse(40ms)with no evidence of gross instabilities.

关键词： field rotating reversed

Acetaminophen-induced Liver Injury: from Animal Models to Humans

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Journal of Clinical and Translational Hepatology 2014年第3期2卷 153-161页

作者： Hartmut Jaeschke Yuchao Xie Mitchell r.McGill Department of Pharmacology Toxicology & Therapeutics University of Kansas Medical Center Kansas City KS USA

Drug-induced liver injury is an important clinical problem and a challenge for drug *** progress in understanding rare and unpredictable (idiosyncratic) drug hepatotoxicity is severely hampered by the lack of relevant animal models,enormous insight has been gained in the area of predictable hepatotoxins,in particular acetaminopheninduced liver injury,from a broad range of experimental ***,mechanisms of toxicity obtained with certain experimental systems,such as in vivo mouse models,primary mouse hepatocytes,and metabolically competent cell lines,are being confirmed in translational studies in patients and in primary human *** this progress,suboptimal models are still being used and experimental data can be confusing,leading to controversial ***,this review attempts to discuss mechanisms of drug hepatotoxicity using the most studied drug acetaminophen as an *** compare the various experimental models that are used to investigate mechanisms of acetaminophen hepatotoxicity,discuss controversial topics in the mechanisms,and assess how these experimental findings can be translated to the *** success with acetaminophen in demonstrating the clinical relevance of experimental findings could serve as an example for the study of other drug toxicities.

关键词： Drug hepatotoxicity Translational studies Necrosis,Sterile inflammation

Woody species composition,diversity and structure of riparian forests of four watercourses types in Burkina Faso

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Journal of Forestry research 2011年第2期22卷 145-158页

作者： Oumarou Sambaré Fidèle Bognounou rüdiger Wittig Adjima Thiombiano Laboratoire de Biologie et Ecologie végétales UFR/SVTUniversité de OuagadougouBP 7021 Ouagadougou 03 Burkina Faso Botanical Institute J. W. Goethe-University Frankfurt/M. Germany

riparian forests are classified as endangered ecosystems in general,particularly in sahelian countries like Burkina Faso because of human-induced alterations and civil engineering *** modification of this important habitat is continuing,with little attention being paid to the ecological or human consequences of these *** objective of this study is to describe the variation of woody species diversity and dynamic in riparian forests on different type of watercourse banks along phytogeographical gradient in Burkina *** woody species were systematically measured in 90 sample plots with sides of 50 m × 20 ***,dominance,frequency and species and family importance values were computed to characterize the species *** diver-sity indices were calculated to examine the heterogeneity of riparian forests.A total of 196 species representing 139 genera and 51 families were recorded in the overall riparian *** species richness of individuals with dbh ≥ 5cm increased significantly from the North to the South along the phytogeographical gradient and varied significantly between the different types of riparian *** in tree species composition between riparian forests was low,which indicates high beta diversity and reflects differences in habitat conditions and *** structural characteristics varied significantly along the phyto-geographical gradient and between the different types of riparian *** diameter class distribution of trees in all riparian forests showed a reverse ＂J＂ shaped curve except riparian forest of stream indicating vegetation dominated by juvenile *** the ecological importance of riparian forest,there is a need to delineate and classify them along watercourses throughout the country.

关键词： biodiversity dynamic species richness rivers streams phytogeographical gradient.

Extra-hepatic manifestations associated with hepatitis E virus infection:a comprehensive review of the literature

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Gastroenterology report 2016年第1期4卷 1-15,I0001页

作者： Fateh Bazerbachi Samir Haffar Sushil K Garg John r Lake Division of Gastroenterology and Hepatology University of MinnesotaMinneapolisMN 55455USA Department of Gastroenterology and Hepatology University of DamascusDamascusSyrian Arab Republic

Background and aims:Hepatitis E virus(HEV)infection is a significant public health problem that afflicts almost 20 million individuals annually and causes acute liver injury in 3.5 million,with approximately 56000 *** with other viral hepatitides,extra-hepatic manifestations could represent an important aspect of this *** spectrum of these manifestations is still *** pancreatitis and neurological,musculoskeletal,hematological,renal,and other immune-mediated manifestations have been *** aim of this article is to comprehensively review the published literature of extra-hepatic manifestations associated with HEV *** sources:We searched the PubMed database using the MeSH term“hepatitis E”and each of the extra-hepaticmanifestations associated with HEV *** language or date restrictions were set in these *** retrieving articles with non-A,non-B hepatitis were *** articles were identified through the reference lists of included ***:Several extra-hepatic manifestations associated with HEV infection have been *** temporal association between some extra-hepatic manifestations and HEV infection and the exclusion of other possible etiologies suggests that HEV infection could have caused some of *** to the available data,HEV infection appears to be strongly associated with acute pancreatitis,neurological disorders(with primarily dominant peripheral nerve involvement,most commonly manifested as Guillain-Barre´syndrome,followed by neuralgic amyotrophy),hematological diseases(hemolytic anemia due to glucose phosphate dehydrogenase deficiency,and severe thrombocytopenia),glomerulonephritis,and mixed *** data are needed to clarify whether an association exists with musculoskeletal or other immunemediated ***:HEV infection should be considered in patients with acute pancreatitis,Guillain-Barre´syndrome,neuralgic amyotrophy,hem

关键词： hepatitis E virus viral hepatitis extra-hepatic manifestations vaccine primary prevention