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Infectious Disease Modelling 2024年第2期9卷 634-643页

作者： Joshua Ladau Eoin L.Brodie Nicola Falco Ishan Bansal Elijah B.Hoffman Marcin P.Joachimiak Ana M.Mora Angelica M.Walker Haruko M.Wainwright Yulun Wu Mirko Pavicic Daniel jacobson Matthias Hess James B.Brown Katrina Abuabara Departments of Computational Precision Health and Der.a.ology University of CaliforniaSan FranciscoCA94115USA Ar.a.Intelligence Inc.Salt Lake CityUT84101USA Computational Biosciences Group Lawrence Berkeley National LaboratoryBerkeleyCA94720USA Earth and Environmental Sciences Area Lawrence Berkeley National LaboratoryBerkeleyCA94720USA Graduate Group in Biostatistics University of CaliforniaBerkeleyCA94720USA Biosystems Data Science Environmental Genomics and Systems BiologyLawrence Berkeley National LaboratoryBerkeleyCA94720USA Center for Environmental research and Community Health(CErCH) School of Public HealthUniversity of CaliforniaBerkeleyCA94720USA Bredesen Center for Interdisciplinary research and Graduate Education University of TennesseeKnoxvilleTN37996USA Department of Nuclear Science and Engineering Massachusetts Institute of TechnologyBostonMA02139USA Biosciences Oak Ridge National LaboratoryOak RidgeTN37830USA University of California DavisCA95616USA Statistics Department University of CaliforniaBerkeleyCA94720USA Division of Epidemiology and Biostatistics University of California Berkeley School of Public Health2121 Berkeley WayBerkeleyCA94720USA

Objectives We aim to estimate geographic var.a.ility in total numbers of infections and infection fatality ratios(IFr;the number of deaths caused by an infection per 1,000 infected people)when the availability and quality of data on disease burden are limited during an *** We develop a noncentral hypergeometric framework that accounts for differential probabilities of positive tests and reflects the fact that symptomatic people are more likely to seek *** demonstrate the robustness,accuracy,and precision of this framework,and apply it to the United States(U.S.)COVID-19 pandemic to estimate county-level SArS-CoV-2 *** The estimators for the numbers of infections and IFrs showed high accuracy and precision;for instance,when applied to simulated validation data sets,across counties,Pearson correlation coefficients between estimator means and true values were 0.996 and 0.928,respectively,and they showed strong robustness to model *** the county-level estimators to the r.a.,unsimulated COVID-19 data spanning April 1,2020 to September 30,2020 from across the U.S.,we found that IFrs varied from 0 to 44.69,with a standard deviation of 3.55 and a median of *** The proposed estimation framework can be used to identify geographic var.a.ion in IFrs across settings.

关键词： Infection fatality ratio Infection fatality rate Noncentral hypergeometric distribution COVID-19 SArS-CoV-2

Evaluation of natural goethite on the removal of arsenate and selenite from water

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Jour.a. of Environmental Sciences 2019年第2期31卷 133-141页

作者： Andrew T.jacobson Maohong Fan Department of Chemical Engineering University of Wyoming

Elevated arsenic and selenium concentrations in water cause health problems to both humans and wildlife. Natural and anthropogenic activities have caused contamination of these elements in waters worldwide, making the development of efficient cost-effective methods in their removal essential. In this work, removal of arsenate and selenite from water by adsorption onto a natural goethite(α-FeO OH) sample was studied at varying conditions. The data was then compared with other.a.senate, selenite/goethite adsorption systems as much of literature shows discrepancies due to varying adsorption conditions. Characterization of the goethite was completed using inductively coupled plasma mass spectrometry, X-ray diffraction, Fouriertransform infrared spectroscopy, scanning electron microscopy, and Brunauer–Emmett–Teller sur.a.e ar.a.analysis. Pseudo-first order(PFO) and pseudo-second order(PSO) kinetic models were applied; including comparisons of different regression methods. Various adsorption isotherm models were applied to determine the best fitting model and to compare adsorption capacitates with other works. Desorption/leaching of arsenate and selenite was studied though the addition of phosphate and hydroxyl ions. Langmuir isotherm modeling resulted in maximum adsorption capacities of 6.204 and 7.740 mg/g for.a.senate and selenite adsorption,respectively. The PSO model applied with a non-linear regression resulted in the best kinetic fits for both adsorption and desorption of arsenate and selenite. Adsorption decr.a.ed with incr.a.ing pH. Phosphate induced desorption resulted in the highest percentage of arsenate and selenite desorbed, while hydroxide induced resulted in the fastest desorption kinetics.

关键词： Arsenic Selenium Adsorption Desorption FeOOH Water tr.a.ment

Synthesis and Structures of A Series of Novel rare Earth Transition Metal Sulfates

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Jour.a. of rare Earths 2006年第6期24卷 659-662页

作者：王希渠刘鲁美 Allan J.jacobson Department of Chemistry and Texas Center for Superconductivity University of Houston Houston TX 77204-5003USA

Seven new rare earth transition metal sulfates were synthesized by hydrother.a. r.a.tions under conditions slightly above the critical point of water. Their crystal structures were determined from single crystal X-ray data. The compositions of the new compounds can be represented by two general formulae ： rEM （OH） 3 （SO4） and rE2M （OH） 3 （SO4） 2F （H2O） with rE = Gd, Tb, Dy ; M = Ni, Cu. Three different crystal structure types were found for the formula rEM （OH） 3 （SO4）. The structures of the new compounds all feature infinite chains of rEOn coordination polyhedra, which are connected to chains of CuO6 or NiO6 octabedra. The limited size range of the rare earth cations observed in these compounds is most likely because of interactions between the octabedral chains and the chains of rEOn polyhedra. The new compounds are closely related to the known yttrium transition metal sulfates.

关键词： rare earth sulfate transition metal sulfate hydrother.a. synthesis crystal structure

Analysis of genetic diversity in banana cultivars(Musa cvs.) from the South of Oman using AFLP markers and classification by phylogenetic,hierarchical clustering and principal component analyses

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Jour.a. of Zhejiang University-Science B(Biomedicine & Biotechnology) 2010年第5期11卷 332-341页

作者： Umezuruike Linus OPArA Dan jacobson Nadiya Abubakar.a.-SAADY Department of Horticultural Science Faculty of AgricSciencesUniversity of Stellenbosch Department of Viticulture and Oenology Institute of Wine BiotechnologyFaculty of AgricSciencesUniversity of Stellenbosch Department of Crop Sciences College of Agricultural and Marine SciencesSultan Qaboos University

Banana is an impor.a.t crop grown in Oman and there is a dearth of infor.a.ion on its genetic diversity to assist in crop breeding and improvement *** study employed amplified fragment length polymorphism(AFLP) to investigate the genetic var.a.ion in local banana cultivars from the southern region of *** 12 primer combinations,a total of 1094 bands were scored,of which 1012 were ***-two unique markers were identified,which revealed the distinct separation of the seven *** results obtained show that AFLP can be used to differentiate the banana *** classification by phylogenetic,hierarchical clustering and principal component analyses showed significant differences between the clusters found with molecular markers and those clusters cr.a.ed by previous studies using morphological *** on the analytical results,a consensus dendrogram of the banana cultivars is presented.

关键词： Musa Genetic diversity Amplified fragment length polymorphism(AFLP) Phylogenetics Principal component analysis(PCA) Hierarchical clustering analysis(HCA) Oman

recovery rates of persistent post-COVID-19 olfactory dysfunction using psychophysical assessment:A longitudinal cohort study

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World Jour.a. of Otorhinolaryngology-Head and Neck Surgery 2024年第2期10卷 79-87页

作者： Jeremy P.Tervo Patricia T.jacobson Brandon J.Vilarello Tiana M.Saak Francesco F.Car.a.a Liam W.Gallagher Joseph B.Gary David A.Gudis Paule V.Joseph D.P.Devanand Terry E.Goldberg Jonathan B.Overdevest Columbia University Vagelos College of Physicians and Surgeons New YorkNew YorkUSA Department of Otolaryngology-Head and Neck Surgery New York-Presbyterian/Columbia University Irving Medical CenterNew YorkNew YorkUSA Department of Otolaryngology-Head and Neck Surgery University of PittsburghPittsburghPennsylvaniaUSA Department of Otolaryngology-Head and Neck Surgery University of MinnesotaMinneapolisMinnesotaUSA National Institute of Alcohol Abuse and Alcoholism Section of Sensory Science and Metabolism&National Institute of Nursing ResearchBethesdaMarylandUSA New York-Presbyter.a./Columbia University Irving Medical Center New YorkNew YorkUSA

Objectives:Persistent olfactory dysfunction(OD)following loss of smell associated with SArS-CoV-2 infection is a major feature of long *** on the prevalence of persistent OD predominantly rely on self-reported olfactory *** studies have tracked longitudinal rates of recovery using psychophysical assessment among patients presenting for evaluation of persistent OD beyond a window of acute *** anchored in standardized testing methods are needed to counsel patients who fail to acutely regain their sense of *** study aims to quantify the degree of persistent OD in post-COVID-19 patients who experience subjective and psychophysical ***:We grouped participants presenting for OD evaluation into cohorts based on both subjective and psychophysical olfactory status at a baseline assessment and assessed their olfactory abilities with a visual analogue scale and the Sniffin'Sticks extended test at baseline and 1-year time *** had confirmed a history of COVID-19 by lab evaluation or clinical diagnosis if lab evaluation was not ***:Baseline olfactory evaluation was completed by 122 participants,53 of whom completed the 1-year follow-up *** participants presenting with perceived OD,74.5%had confirmed psychophysical OD at baseline,with 55.1%at 1-year *** had reliable trends in self-rated versus psychophysically tested olfactory function at both time *** total threshold,discrimination,and identification(TDI)score improved by+3.25 points in the cohort with psychophysical OD(p=0.0005),with this improvement largely attributable to an incr.a.e in median threshold scores(+2.75 points;p=0.0004).Conclusions:OD persists in a significant number of patients who fail to acutely recovery their sense of smell after COVID-19,with many demonstrating lingering deficits at *** in threshold,but not discrimination or identification,most significantly mediate improvement

关键词： long COVID olfaction post-COVID condition smell dysfunction

Or.a.izational Changes Needed in Disasters and Public Health Emergencies:A Qualitative Study among Managers at a Major Hospital

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Inter.a.ional Jour.a. of Disaster risk Science 2022年第4期13卷 481-494页

作者： Ingela Wennman Catharina jacobson Eric Carlström Anders Hyltander.a.ir Khor.a.‑Manesh Institute of Health and Care Sciences Sahlgrenska AcademyGothenburg University41346GothenburgSweden Preparedness Unit Sahlgrenska University Hospital41305 GothenburgSweden Institute of Clinical Sciences Department of SurgerySahlgrenska AcademyGothenburg University41345GothenburgSweden

Most hospitals have a contingency plan,based on all-risks and all-hazards assessment ***,emerging thr.a.s and risks often necessitate a flexible appr.a.h to emergency management at several levels of a disaster response system,for example,in ***,and possibly other countries,has limited possibilities of surge capacity in the management of large-scale disasters and emergencies,which necessitates a local/national partnership and a flexible local disaster.a.d contingency *** study evaluates the opinions of a selected manager.a. group,both at operative and strategic levels,regarding possible changes in a major hospital's contingency plan during the ongoing COVID-19 *** interviews were conducted to explore the elements of surge capacity and an operational tool,consisting of command and control,safety,communication,assessment,tr.a.e,tr.a.ment,and *** results show a need to cr.a.e feasible management methods that can be evaluated,establish clear leadership,put preparedness as a constant point on the highest manager.a. agenda,improve exter.a. monitoring,and cr.a.e a regional coordinating ***,the results emphasize the significant role played by the incident command system and qualified leadership to facilitate competent and crucial medical decision making,as well as to provide reliable communication,collaboration,and coordination in a multi-agency response system during dynamic and unexpected *** steps enable a constant connection between r.a.tive contingency plans and the pr.a.tivity in continuous risk assessment and enhance the flexibility of the contingency plans.

关键词： Disaster risks Or.a.izational changes Public health emergencies Sweden

Environmental temperatures,physiology and behavior limit the range expansion of invasive Burmese pythons in southeastern USA

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Integrative Zoology 2012年第3期7卷 271-285页

作者： Elliott r.jacobson David G.BArKEr Tracy M.BArKEr richard MAULDIN Michael L.AVErY richard ENGEMAN Stephen SECOr College of Veterinary Medicine University of FloridaGainesvilleFlorida Vida Preciosa Inter.a.ional(VPI) BoerneTexas US Department of Agriculture Wildlife ServicesNational Wildlife Research CenterFort CollinsColorado US Department of Agriculture Wildlife ServicesNational Wildlife Research CenterGainesvilleFlorida Department of Biological Sciences University of AlabamaTuscaloosaAlabamaUSA

A well-established population of Burmese pythons resides in the Everglades of southern *** in part by a report that identified much of southern USA as suitable habitat for expansion or establishment of the Burmese python,we examined the plausibility of this snake to survive winters at sites north of the *** integrated daily low and high temperatures recorded from October to Febr.a.y from 2005-2011 at Homestead,Or.a.do and Gainesville,Florida;and Aiken,South Carolina,with minimum temperatures projected for python digestion(16℃),activity(5℃)and survival(0℃).Mean low and high temperatures decr.a.ed northward from Homestead to Aiken and the number of days of freezing temperatures incr.a.ed *** was impaired or inhibited for 2 months in the Everglades and up to at least 5 months in Aiken,and activity was incr.a.ingly limited northward during these *** of overwinter survivorship document that a single bout of low and freezing temperatures results in python *** capacity for Burmese pythons to successfully overwinter in more temperate regions of the USA is seemingly prohibited because they lack the behaviors to seek refuge from,and the physiology to tolerate,cold *** tropical Southeast Asia is the source of the Everglades Burmese pythons,we predict it is unlikely that they will be able to successfully expand to or colonize more temperate ar.a. of Florida and adjoining states due to their lack of behavioral and physiological traits to seek refuge from cold temperatures.

关键词： ambient temperature Burmese python invasion snake ther.a. tolerance

The aggressive invasion of exotic reptiles in Florida with a focus on prominent species： A review

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Current Zoology 2011年第5期57卷 599-612页

作者： richard ENGEMAN Elliott jacobson Michael L. AVErY Walter E. MESHAKA, Jr. USDA/APHIS/Wildlife Services/National Wildlife research Ctr 4101 LaPorte Ave. Fort Collins CO 80521-2154 USA College of Veterinary Medicine University of Florida Gainesville FL 32610 USA USDA/APHIS/Wildlife Services/National Wildlife research Ctr 2820 East University Ave. Gainesville FL 32641 USA The State Museum of Pennsylvania 300 North Street Harrisburg Pennsylvania 17120 USA

Florida, along with Hawaii, has among the two worst invasive species problems in the USA, and the state is espe-cially susceptible to establishment by alien reptiles. Besides the large numbers of established non-native reptile species in Florida, many of these species present novel difficulties for management, or have other characteristics making effective management ex-tremely challenging. Moreover, initiation of management action requires more than recognition by experts that a potentially harmful species has become established. It also requires the political will along with concomitant resources and appropr.a.e per-sonnel to develop effective methods and apply them. We review the situation in Florida, including assessment of risk for estab- lishment, and we use a subset of prominent species to illustrate in more detail the ar.a. of invasive reptile species circumstances in Florida, including routes of introduction, impacts, and potential and implemented management actions. These examples not only highlight the severity of the invasive reptile problems in the state, but they also show the diversity in resolve and response towards them and the motivating factors [Current Zoology 57 （5）： 599-612, 2011].

关键词： Argentine black and white tegus Biophysical ecology Burmese pythons Control Green and spiny-tailed iguanas,Invasive species Nile monitors Northern curlytail lizards

Fundamentals of machine elements / Ber.a.d J. Hamrock, Bo O. jacobson, Steven r. Schmid.

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