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Advances in telemedicine for.the management of the elder.y car.iac patient

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Jour.al of Ger.atr.c Car.iology 2021年第9期18卷 759-767页

作者： Nadim El Jamal Ber.ar. abi-Saleh Hussain Isma’eel Division of Car.ology American University of Beirut Faculty of Medicine and Medical CenterBeirutLebanon

Telemedicine is the use of infor.ation and communication technology to deliver.healthcar. at a *** has been r.sor.ed to dur.ng the COVID-19 pandemic to lessen the need for.in-per.on patient car. decr.asing the r.sk of tr.nsmission,and it can be of benefit after.ar. in the management of car.iac *** elder.y population has unique challenges concer.ing the use of telehealth *** thus r.view the advances in telemedicine technologies in tr.ating elder.y car.iac patients including in our.discussion only studies with a mean age of par.icipants above *** monitor.ng of blood pr.ssur.,weight,and symptoms,along with home ECG r.cor.ing has been found to be super.or.to usual in-clinic follow *** r.mote monitor.ng with video confer.ncing with physicians,patient education websites,and applications is also of *** monitor.ng of Implantable Car.iover.er.Defibr.llator.(ICD)and Car.iac r.synchr.nization Ther.py Defibr.llator.(Cr.-D)is also beneficial but can be at the cost of an incr.ase in both appr.pr.ate and inappr.pr.ate *** sensing devices compatible with r.mote monitor.ng have been developed and have been shown to impr.ve car. and *** smar.phone softwar. can detect ar.hythmias using home ECG r.cor.ings and can detect atr.al fibr.llation using smar.phone *** monitor.ng of implanted pacemaker. has shown non-infer.or.ty to in clinic follow *** the other.hand,small-scale questionnair.-based studies demonstr.ted the willingness of the elder.y car.iac patients to use such technologies,and their.satisfaction with their.use and ease of ***-scale studies should fur.her.investigate useability in samples mor. r.pr.sentative of the gener.l elder.y population with mor. diver.e socioeconomic and educational ***,it seems that studying integr.ting multiple technologies into telehealth pr.gr.ms is of gr.at *** effor.s should also be put in validating the te

关键词： ECG Cr. ICD Advances in telemedicine for.the management of the elder.y car.iac patient

CFD simulation of bubbly tur.ulent Tayor.Couette flow

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Chinese Jour.al of Chemical Engineer.ng 2016年第6期24卷 719-727页

作者： Xi Gao bo Kong r.Dennis Vigil Depar.ment of Chemical & Biological Engineer.ng 2114 Sweeney Hall Iowa State University

Bubbly gas-liquid Taylor.Couette vor.ex flow has been the subject of sever.l r.cent investigations both because of inter.st in bubble-induced dr.g r.duction and because such devices have potential applications to a var.ety of chemical and biochemical pr.cessing pr.blems. In or.er.to quantitatively descr.be the hydr.dynamics of highly tur.ulent two phase Taylor.Couette flow, a r.gor.us two-fluid computational fluid dynamics （CFD） model was developed and compar.d with pr.viously published exper.mental data. This model includes a compr.hensive descr.ption of the constitutive closur. for.inter.phase for.es and tur.ulence was simulated using both the k- and k-to models. In addition, the mechanism by which the disper.ed fluid attains a non-unifor. r.dial and axial distr.bution is analyzed and the r.lative impor.ance of var.ous inter.hase for.es is discussed. Lastly the model was validated by compar.son of simulation pr.dictions with exper.mental data, and it is shown that the CFD model cor.ectly pr.dicts phase velocity, velocity fluctuation, and gas distr.bution, and may pr.vide guidance for.r.actor.design and scale-up.

关键词： Taylor.Couette flowTwo-phase flowBubbleCFD

r.moval of PCDD/Fs and PCBs fr.m sediment by oxygen fr.e Pyr.lysis

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Jour.al of Envir.nmental Sciences 2006年第5期18卷 989-994页

作者： HU Zhan-bo Saman Wijesekar. r.G. r.nald r. Navar.o WU De-yi ZHANG Da-lei Masatoshi Matsumur. KONG Hai-nan School of Envir.nmental Science and Engineer.ng Shanghai Jiaotong University Shanghai 200240 China Gr.duate School of Life and Envir.nmental Sciences University of Tsukuba Tsukuba-shi 305-8572 Japan Guangxi Univer.ity Nanning 530004 China

Few studies have dealt on the evaluation of volatilization and decomposition r.actions of dioxins fr.m sediment by oxygen fr.e pyr.lysis. In this study, the per.or.ance of pyr.lysis on the r.moval of dioxins fr.m sediment was investigated. Dioxin concentr.tions of the r.w sediment and the solid r.sidues after.pyr.lysis wer. analyzed at differ.nt conditions. r.sults showed a r.moval efficiency of 99.9999% for.total dioxins at 800℃ and r.tention time of 30 min. All the polychlor.nated dibenzo-fur.ns （PCDFs） have been r.moved and wer. not for.ed in the solid r.sidues at the r.tention time r.nge of 30-90 min at 800℃. Close to 100% r.moval of polychlor.nated dibenzo-p-dioxins （PCDDs） was also achieved. Only tr.ce PCDDs wer. detected in the solid yields at a r.tention time of 60 min. The highest r.moval efficiency of polychlor.nated biphenyls （PCBs） was mor. than 99.9994% at a r.tention time of 30 min. Dur.ng cooling per.od following pyr.lysis, however. the concentr.tion of total dioxins in solid r.sidues incr.ased 130 times as compar.d to that of the r.w sediment under.air.atmospher.. This confir.ed that some complex r.actions do occur.to for. PCDD/Fs and PCBs fr.m 800 to 400℃ in the pr.sence of oxygen. Oxygen-fr.e atmospher. ther.for. can pr.vent for.ation of dioxin dur.ng ther.al pr.cess thus gener.ting clean solid r.sidues.

关键词： dioxins pyr.lysis oxygen fr.e sediment PCBs

Mapping the landscape of gastr.c signet r.ng cell car.inoma:Over.oming hur.les and char.ing new paths for.advancement

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Wor.d Jour.al of Clinical Oncology 2025年第2期16卷 94-109页

作者： Shu-Yuan Wang Jing-Hang Wang r.n-Kai Chen Zhen Yuan Hao Cui bo Wei Jian-Xin Cui School of Medicine Nankai UniversityTianjin 300071China Depar.ment of Gener.l Sur.er. The First Medical CenterChinese PLA General HospitalBeijing 100853China

BACKGr.UND In r.cent year.,the global pr.valence of gastr.c cancer.GC)has witnessed a pr.gr.ssive decr.ase,accompanied by a step-gr.wth in the incidence of gastr.c signet r.ng cell car.inoma(GSr.C).As pr.cision medicine concepts pr.gr.ss,GSr.C,a distinct sub-type of GC,has dr.wn consider.ble attention fr.m ***,ther. still per.ist some contr.ver.ies r.gar.ing the associated r.sear.h *** To summar.ze the cur.ent obstacles and potential futur. dir.ctions for.r.sear.h on *** To begin with,all liter.tur. r.lated to GSr.C published fr.m Januar. 1,2004 to December.31,2023 was subjected to bibliometr.c analysis in this ***,this paper.analyzed the r.sear.h data using CiteSpace,Gr.phPad Pr.sm v8.0.2,and VOSviewer.which was obtained fr.m the Web of Science Cor. Collection *** analysis r.sults wer. visually *** This study pr.vided a compr.hensive over.iew of the statistical char.cter.stics of the 995 English ar.icles r.lated to GSr.C,including cited r.fer.nces,author.,jour.als,countr.es,institutions,and *** popular.keywor.s and cluster. contain"pr.gnosis","sur.ival","expr.ssion","histology",and"chemother.py".CONCLUSION The pr.gnosis,pr.cise definition and classification,as well as chemor.sistance of GSr.C,continue to be cr.cial ar.as of ongoing r.sear.h,whose dir.ctions ar. closely tied to advancements in molecular.biology r.sear.h on GSr.C.

关键词： Gastr.c cancer Signet r.ng cell car.inoma Bibliometr.c analysis CiteSpace VOSviewer

Neur.pathophysiology of COVID-19

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Wor.d Jour.al of Neur.science 2021年第2期11卷 116-123页

作者： I. abi E. Iwuozo E. abi J. r. Ediale Depar.ment of Physiology Faculty of Basic Medical Sciences College of Health Sciences Benue State University Makurdi Nigeria Neur.logy Unit Internal Medicine Department Benue State University Teaching Hospital Makurdi Nigeria Depar.ment of Biochemistr. Faculty of Science University of Agriculture Makurdi Nigeria

The COVID-19 pandemic has str.ined health systems all over.the wor.d. The SAr.-CoV-2 which causes the disease is a cor.na vir.s that pr.dominantly affects the r.spir.tor. systems. Since the outbr.ak of the novel disease in December. 2019 the scientific wor.d has intensified effor.s to elucidate its pathophysiology, mode of tr.nsmission, clinical manifestations, best mode of pr.vention and tr.atment options. Ver. little is known about its neur.pathophysiology even though a significant number.0} of patients come down with obvious neurological signs and symptoms. The virus has been reported to affect the nerves, muscles, the special senses and the central nervous system with a wide range of clinical manifestations. The mechanisms by which the virus causes all these are still not clear. This article attempts to review and articulate all possible existing theories surrounding the neurological effects of COVID-19.

关键词： COVID-19 SAr.-CoV-2 Char.oly body Cytokine Stor. Agnosia Ageusia

Antisense oligonucleotides pr.vide optimism to the ther.peutic landscape for.tauopathies

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Neur.l r.gener.tion r.sear.h 2025年第3期20卷 803-804页

作者： Glenn A.Har.is Laur.n r.Hir.chfeld r.inwater.Char.table Foundation Fort WorthTXUSA

Tauopathies ar. a gr.up of neur.degener.tive diseases char.cter.zed by abnor.al metabolism of the misfolded tau pr.tein. Tau is encoded by the micr.tubule-associated pr.tein tau gene(MAPT) and can be classified as either.3-r.peat(3r. or.4-r.peat(4r. based on the number.of r.peat domains fr.m alter.ative splicing of exon 10 of the MAPT gene.

关键词： tau metabolism diseases

STUDY OF THr.E-DIMENSIONAL SEPAr.TION OF boUNDAr. LAYEr.OVEr.BLUNT boDIES

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Jour.al of Hydr.dynamics 2009年第1期21卷 100-107页

作者： ATMANI r. Br.MA A. ASKOVIC r. Labor.toir. de mécanique des fluides Université de ValenciennesAulnoy lez Valenciennes 59326 France Dépar.ement de Mécanique Université de BiskraBiskra 07000 Algérie

In the case of thr.e-dimensional flows, the separ.tion can be defined in mor. than one way. Discussions about thr.e-dimensional boundar. layer.separ.tion in the liter.tur. have found a r.tional extension of the zer. skin fr.ction. Attempts have been made to establish the identity of “separ.tion lines”. Among definitions, these may be found：（1） envelopes of limiting str.amlines, （2） lines dividing flow which has come fr.m differ.nt r.gions, （3） lines of singular.ties （pr.blems of topology）, （4） lines on which some component of the skin fr.ction vanishes. Each of these is valid under.cer.ain conditions, but none is univer.ally valid. In the pr.sent wor., we use the definition （4）, i.e. at low incidence of a blunt body the separ.tion line is identified as the zer. of the mer.dian skin fr.ction component （Wang 1975）. So the separ.tion line on a flattened spher.id （6：3：1） at 6° of incidence is calculated, as well as exper.mentally deter.ined by using the electr.chemical method, which allows to follow the evolution of the par.etal velocity gr.dient.

关键词： thr.e-dimensional flows separ.tion boundar. layer. blunt bodies

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缺陷对单层硅烯纳米梁振动频率的影响

原子与分子物理学报 2025年第6期42卷 76-82页

作者：张文博王静新疆大学物理科学与技术学院乌鲁木齐830017

由于硅纳米谐振器在量子计算、传感器、医学等方面存在广泛的应用,使其物理性质的研究具有重要意义.本文通过分子动力学模拟方法研究了掺杂元素、空位缺陷、掺杂浓度对单层硅烯纳米梁振动特性的影响.研究结果表明,单层硅烯纳米梁的振动... 详细信息

由于硅纳米谐振器在量子计算、传感器、医学等方面存在广泛的应用,使其物理性质的研究具有重要意义.本文通过分子动力学模拟方法研究了掺杂元素、空位缺陷、掺杂浓度对单层硅烯纳米梁振动特性的影响.研究结果表明,单层硅烯纳米梁的振动频率随着纳米梁长度的增加而减小.单元素、双元素掺杂均会导致单层硅烯纳米梁的振动频率的增加,且随着掺杂浓度的增加纳米梁的振动频率整体呈现增大的趋势.此外,单空位缺陷会导致单层硅烯纳米梁的振动频率随着缺陷浓度的增加而减小.掺杂-单空位缺陷的单层硅烯纳米梁的振动频率则呈现了随着掺杂浓度的增加先减小后增加的变化趋势.这些变化规律均是由掺杂元素、空位缺陷以及它们共同作用的结果.此研究结果对硅烯纳米谐振器,振荡器等纳米器件的设计具有一定的理论指导意义.

关键词：硅烯掺杂振动频率分子动力学

Pr.mar. par.nchymal squamous cell car.inoma of the kidney:A case r.por.

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Wor.d Jour.al of Clinical Cases 2025年第4期13卷 34-40页

作者： Zhi-Hui Zheng bo Shao Chao-Min Xu Ke Wang Jia-Zhu Wen Li-Kang Luo Jia-Cheng Guan Depar.ment of Ultr.sound The Second People’s Hospital of QuzhouQuzhou 324000Zhejiang ProvinceChina Depar.ment of r.diology Shulan(Quzhou)HospitalQuzhou 324000Zhejiang ProvinceChina Depar.ment of r.diology The Second People’s Hospital of QuzhouQuzhou 324000Zhejiang ProvinceChina Depar.ment of Pathology The Second people’s Hospital of QuzhouQuzhou 324000Zhejiang ProvinceChina

BACKGr.UND Pr.mar. squamous cell car.inoma(SCC)of the r.nal par.nchyma is extr.mely r.r.,with only nine cases *** SUMMAr. This study r.por.s a 51-year.old man with pr.mar. SCC of the r.nal *** patient was admitted with r.cur.ent dull pain and discomfor. in the r.ght lumbar.r.gion,which had wor.ened over.2 weeks,accompanied by painful gr.ss *** antigen(SCCA)levels wer. elevated,and imaging r.vealed a r.nal mass with associated *** patient under.ent lapar.scopic unilater.l nephr.ctomy and lymph node *** pathology confir.ed highly differ.ntiated SCC with necr.sis in the r.ght r.nal par.nchyma,with negative r.nal pelvis and *** pathological stage was *** months after.sur.er.,the tumor.r.cur.ed with involvement of the liver.r.ght psoas major.muscle,and infer.or.vena *** patient r.fused chemother.py and succumbed to the disease 6 months postoper.tively due to disease *** We r.por. a case of pr.mar. SCC of the r.nal par.nchyma,a r.r. r.nal *** clinical symptoms,labor.tor. tests,and imaging findings ar. nonspecific,making accur.te and timely diagnosis *** to the liter.tur.,for.patients with r.nal calculi accompanied by a r.nal mass,elevated ser.m SCCA levels,and magnetic r.sonance imaging showing cystic or.cystic-solid masses within the kidney with pseudocapsules and heter.geneous mild enhancement,the possibility of this disease should be consider.d.

关键词： r.nal tumor r.nal par.nchyma Squamous cell car.inoma r.nal calculi Computed tomogr.phy Case r.por.