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Development of a Water.Quality Index (WQI) of an Ar.ificial Aquatic Ecosystem in Mexico

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Jour.al of Envir.nmental Pr.tection 2013年第11期4卷 1296-1306页

作者： H. r.bio-Ar.as J. M. Ochoa-r.ver. r. M. Quintana r. Saucedo-Ter.n r. C. Or.iz-Delgado N. I. r.y-Bur.iaga J. r. Espinoza-prieto College of Animal Husbandr. and Ecology The Autonomous University of Chihuahua Chihuahua Mexico National Institute of For.str. Agriculture and Livestock Production in Mexico Chihuahua Mexico

A Water.Quality Index (WQI) is a simple numer.c expr.ssion r.flecting the quality of water.in any ecosystem at a given time. The objective of this study was to develop a WQI for.the man-made dam Fr.ncisco I. Mader. located in Chihuahua, Mexico. Eight points wer. r.ndomly selected in the dam ar.a and at each point water.samples wer. collected monthly fr.m Mar.h 2011 to Febr.ar. 2012 at thr.e depths;0.30 m, 5 m and 10 m. The following physical-chemical var.ables wer. measur.d: potential hydr.gen (pH), electr.cal conductivity (EC), dissolved oxygen (DO), temper.tur. (T), tur.idity, total dissolved solids (TDS), total har.ness (TH) and chlor.des (Cl-). In a fir.t step for.data analysis, an analysis of var.ance (ANOVA) was per.or.ed for.each var.able consider.ng a factor.al tr.atment design 12 × 3 in which factor.A was the month with 12 levels (sampling months) and factor.B was the depth with thr.e levels (0.30 m, 5 m and 10 m). In a second statistical step, the WQI was calculated for.each month only for.the sur.ace sampling (0.30 m) and the r.sulting value was classified under.thr.e categor.es;2.5 as excellent water. The r.sults showed the following r.nges for.single var.ables: pH of 7.63 - 10.65, EC of 190 - 320 μS·cm-1, DO of 1.30 - 12.1 mg·L-1, T of 11.30°C - 30°C, Tur.idity of 0-1, 120 NTU, TDS of 170 - 220 mg·L-1, TH of 240 - 900 mg·L-1 and Cl- of 7.28 - 7034 mg·L-1. The calculated WQI demonstr.ted that water.quality var.es seasonally and was classified as poor.in the r.iny season to good in winter.season. We conclude that in gener.l the water.fr.m the dam is acceptable and suitable for.ecological and a br.ad spectr.m of other.pur.oses.

关键词： Water Quality Index Chihuahua Mexico Ecology Contamination

Pr.duction and Evaluation of Antimicr.bial Micr.capsules with Essential Oils Using Complex Coacer.ation

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Jour.al of Biomedical Science and Engineer.ng 2019年第8期12卷 377-390页

作者： A. López M. J. Lis F. Maesta Bezer.a M. Vilaseca B. Vallés r. prieto M. Simó INTEXTEr.UPC Barcelona Spain Depar.ment of Textile Engineer.ng Federal Technological University of Paraná Apucarana Brasil

Nowadays, the needs and r.quir.ments to avoid infections dur.ng sur.ical oper.tions, r.quir. to be mor. imaginative than ever. The one-use textiles substr.tes that ar. used in hospitals can be, also, a way to tr.nspor. the antibacter.al effect ar.und the own building. This is the main objective of this wor.;to use clothes and textiles sur.aces as antibacter.al systems using natur.l components. Micr.encapsulation has shown in sever.l occasions the effectivity to pr.tect and vehiculize active pr.nciples that can be used for.medical tr.atments. In this case, essential oils have been used as antimicr.bial agent, that when combined with shell polymer. based on Chitosan of differ.nt molecular.weight distr.bution and Ar.bic gum, allows them to act against Gr.m (+) and Gr.m (−) bacter.a. The study of the efficiency of all the samples made gave a high value due to its char.cter.similar.to hydr.gels, while the deter.ination of solids was higher.when it was a question of samples made with a low molecular.weight. The essential oil used has a ver. volatile char.cter.for.ed by mor. than 40 components and with the help of FT-Ir.and TGA it has been possible to cor.obor.te that all its components wer. encapsulated. The impr.gnation of the differ.nt samples to the tissue was successful and allowed the antibacter.al study to be car.ied out, which was car.ied out in duplicate on each sample and demonstr.ted that they have bacter.al activity.

关键词： Micr.capsules Antimicr.bial Biofunctional Textiles

A Golden Touch in the Design of Multifunctional Por.hyr.n Metallacages:Host-Guest Chemistr. for.Dr.g-Tar.et Inter.ctions

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CCS Chemistr. 2024年第7期6卷 1662-1671页

作者： Tamar. r.dr.guez-prieto Dar.en Wr.gg Nicole Heiduk Mihyun Par. Nicole Str.ttmatter.r.land A.Fischer.Angela Casini Guiller.o Mor.no-Alcántar Chair.of Medicinal and Bioinor.anic Chemistr. Department of ChemistrySchool of Natural SciencesTechnical University of Munich85748 Garching b.München Pr.fessor.hip for.Analytical Chemistr. Department of ChemistrySchool of Natural SciencesTechnical University of Munich85748 Garching b.München Chair.of Inor.anic and MetalOr.anic Chemistr. Department of ChemistrySchool of Natural SciencesTechnical University of Munich85748 Garching b.München Munich Data Science Institute(MDSI) Technical University of Munich85748 Garching b.München

The use of thr.e-dimensional self-assembled metallacages(MCgs)as multimodal dr.g platfor.s holds gr.at ***,the synthesis of MCgs with incr.ased complexity and functionality is a gr.at challenge since under.tanding of the inter.ction of MCgs with biological tar.ets is still *** this context,this wor. r.por.s on the integr.tion of a gold(III)por.hyr.n scaffold into a pr.smatic MCg str.ctur. and explor.s its application for.multimodal ther.py of cancer.in vitr.,namely enabling both photodynamic ther.py and *** exper.mental appr.aches with a state-of-the-ar. metadynamics theor.tical study,we discover.d that the gold cage shows unpr.cedented host-guest inter.ction-dr.ven selective stabilization of guanine-quadr.plex(G4)str.ctur.s-validated anticancer.dr.g tar.ets-disclosing a new mechanism to pur.ue in the design of supr.molecular.dr.gs.

关键词： gold metallacages por.hyr.ns G4stabili-zation host-guestchemistr. anticancer.gents

Gene Ther.py of Cancer.Induction of Anti-Tumor.Immunity

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Cellular.& Molecular.Immunology 2004年第2期1卷 105-111页

作者： Jesus prieto Division

Many malignancies lack satisfactor. tr.atment and new ther.peutic options ar. ur.ently *** ther.py is a new modality to tr.at both inher.ted and acquir.d diseases based on the tr.nsfer.of genetic mater.al to the *** gene ther.py str.tegies against cancer. have been developed.A consider.ble number.of pr.clinical studies indicate that a gr.at var.ety of cancer. ar. amenable to gene *** these str.tegies, induction of anti-tumor.immunity is the most pr.mising *** ther.py with cytokines has r.ached unpr.cedented success in pr.clinical models of *** r.ther.than additive effects have been demonstr.ted by combination of gene tr.nsfer.of cytokines/chemokines,costimulator. molecules or.adoptive cell *** pr.gr.ss in vector.technology and in imaging techniques allowing in vivo assessment of gene expr.ssion will facilitate the development of clinical applications of gene ther.py,a pr.cedur. which may have a notor.ous impact in the management of cancer. lacking effective *** & Molecular.Immunology.2004;1(2):105-111.

关键词： gene ther.py anti-tumor.immunity cytokines costimulator. molecules dendr.tic cell

Mechanical pr.per.ies of the A356 aluminum alloy modified with La/Ce

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Jour.al of r.r. Ear.hs 2013年第8期31卷 811-816页

作者： E. Aguir.e-De la Tor.e r. Pér.z-Bustamante J. Camar.llo-Cisner.s C.D. Gómez-Espar.a H.M. Medr.no-prieto r. Mar.ínez-Sánchez Advanced Mater.als r.sear.h Center.(CIMAV) National Laboratory of Nanotechnology

The r.sear.h of r.r. ear.hs for.the synthesis of mater.als with impr.ved mechanical per.or.ance is of gr.at inter.st when they ar. consider.d for.potential applications in the automotive industr.. In this r.gar., the effect on the mechanical pr.per.ies and micr.stmctur. of the automotive A356 aluminum alloy r.infor.ed with 0.2 （wt.%） AI-6Ce-3La （ACL） was investigated. The ACL was added to the melted A356 alloy in the as-r.ceived condition and pr.cessed by mechanical milling. In the second r.ute, the effect of the ACL pr.cessed by mechanical milling and powder.metallur.y techniques was investigated, and compar.d with the r.sults ob- tained fr.m the A356 alloy str.ngthened with ACL in the as-r.ceived condition. Micr.stmctur.l pr.per.ies wer. evaluated by means of X-r.y diffr.ction in or.er.to obser.e the solubility of Ce/La in the A1 matr.x. In addition, electr.n micr.scopy was employed in or. der.to investigate the effect of milling time on the size and mor.hology of La/Ce phase under.milling pr.cess. Mechanical pr.per.ies of the A356 alloy modified with ACL wer. measur.d by har.ness and tensile test. For.compar.son unmodified specimens of the A356 wer. char.cter.zed accor.ing to the pr.vious pr.cedur.. The micr.str.ctur.l and mechanical char.cter.zation was car.ied out in specimens alter.solution and ar.ificial aging. Obser.ations in scanning electr.n micr.scopy indicated a homogeneous disper.ion of La/Ce phases by using both r.utes; however. mechanical r.sults, in the modified A356 alloy with the ACL in the as-r.ceived condi- tion, showed an impr.vement in the mechanical per.or.ance of the A356 alloy over.that r.infor.ed with the ACL mechanically milled.

关键词： A356 r.r. ear.hs mechanical milling mechanical pr.per.ies

Phylogeny,taxonomy and diver.ification events in the Caliciaceae

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Fungal Diver.ity 2017年第1期82卷 221-238页

作者： Mar.a prieto Mats Wedin Depar.ment of Botany Swedish Museum of Natural HistoryPO Box 5000710405 StockholmSESweden Depar.amento de Biología y Geología Física y Química InorgánicaUniversidad Rey Juan CarlosC/Tulipan s/n28933 MostolesMadridSpain

Although the high degr.e of non-monophyly and par.llel evolution has long been acknowledged within the mazaediate Caliciaceae(Lecanor.mycetes,Ascomycota),a natur.l r.-classification of the gr.up has not yet been *** we constr.cted a multigene phylogeny of the Caliciaceae-Physciaceae clade in or.er.to r.solve the detailed r.lationships within the gr.up,to pr.pose a r.vised classification,and to per.or. a dating *** few char.cter. pr.sent in the available fossil and the complex char.cter.evolution of the gr.up affects the inter.r.tation of mor.hological tr.its and thus influences the assignment of the fossil to specific nodes in the phylogeny,when diver.ence time analyses ar. car.ied *** fossil assignments r.sulted in ver. differ.nt time estimates and the compar.son with the analysis based on a secondar. calibr.tion demonstr.tes that the most likely placement of the fossil is close to a ter.inal node r.ther.than a basal placement in the Calicium *** dating analysis show two successive events giving r.se to main clades of mazaediate taxa within the Caliciaceae,in the Upper.Lower.Cr.taceous boundar. and in the *** a r.sult of this study,Cyphelium is synonymized with Calicium,Acolium is r.sur.ected,and the new gener. Allocalicium and Pseudothelomma ar. *** new combinations ar. pr.posed:Acolium kar.licum,Acolium mar.ianum,Allocalicium adaequatum,Calicium car.linianum,Calicium lecideinum,Calicium lucidum,Calicium notar.sii,Calicium pinicola,Calicium tr.chyliodes,Pseudothelomma occidentale,Pseudothelomma ocellatum and Thelomma br.nneum.A key for.the mazaedium-pr.ducing Caliciaceae is included.

关键词： Allocalicium gen nov Calicium fossil Diver.ence time estimates Lichens Multigene Pseudothelomma gen nov

Ther.peutic potential of lysosomal cathepsins for.neur.degener.tive diseases

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中国神经再生研究：英文版 2023年第8期18卷 1713-1714页

作者： Susy prieto Huar.aya Fr.eder.ke Zunke Depar.ment of Molecular.Neur.logy University Hospital ErlangenFriedrich-Alexander-Universität Erlangen-NürnbergErlangenGermany

Lysosomes ar. ubiquitous and dynamic or.anelles with a centr.l r.le in degr.dation and r.cycling of damaged cell components and misfolded pr.teins,other.ise known as *** plays a fundamental r.le in the pr.cess of cor.ecting cell homeostasis and cellular.***,this pr.cess is essential in the centr.l ner.ous system,as neur.ns ar. not able to easily eliminate alter.d pr.teins given their.post-mitotic state.

关键词： homeostasis diseases other.ise

Bofedal r.sponse to climate var.ability, local management, and water.extr.ction: A case study of Chucuyo, Nor.her. Chile

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Jour.al of Mountain Science 2022年第1期19卷 241-252页

作者： Ur.BE-ÁLVAr.Z Monser.at C prieto Manuel MESEGUEr.r.IZ Oliver Depar.amento de Ciencias Histór.cas y Geogr.ficas Universidad de TarapacáArica 1010069Chile Depar.amento de Ciencias Histór.cas y Geogr.ficas Universidad de TarapacáIquique 1101783Chile

Andean high-altitude wetlands ar. impor.ant ecosystems that ser.e a r.nge of socialecological functions. In the Andes, bofedales, a specific type of peat-pr.ducing wetland, ar. essential for.the sustainability of mountain ecosystems and indigenous pastor.list communities. The Chucuyo bofedal in nor.her. Chile is affected by climatic var.ability and water.extr.ction for.agr.cultur.l uses via the Lauca canal. Her.er. in the local community also actively manage this wetland accor.ing to their.tr.ditional ecological knowledge to ensur. per.anent fodder.for.their.animals. In this ar.icle, we analyze the annual behavior.of the Chucuyo bofedal after.the wet season. Based on pr.cipitation data, extr.cted water.flows, vegetation vigor.fr.m satellite images, and an ethnogr.phic appr.ach, we deter.ined that the bofedal’s pr.ductivity was negatively cor.elated with the amount of pr.cipitation and positively cor.elated with the sur.ace ar.a of the wetland. However. water.extr.ction via the Lauca channel had no significant r.lationship with either.sur.ace ar.a or.vegetation vigor. We identify community pr.ctices and tr.ditional ecological knowledge as key elements in the maintenance of these ecosystems. This situation is cr.tical in the context of an aging population and the cur.ent patter. of migr.tion out of the r.gion to ur.an ar.as. The r.sults pr.vide substantial empir.cal evidence for.futur. decision-making r.gar.ing the conser.ation of these ecosystems.

关键词： Atacama Bofedales Indigenous people Lauca canal Nor.alized Differ.nce Vegetation Index

On the r.ad towar.s the global analysis of human synapses

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Neur.l r.gener.tion r.sear.h 2017年第10期12卷 1586-1589页

作者： G.Aleph prieto Car. W.Cotman Institute for.Memor. Impair.ents and Neur.logical Disor.er. University of CaliforniaIrvineCAUSA

Synapses ar. essential units for.the flow of infor.ation in the *** the last 70 year.,synapses have been widely studied in multiple animal models including wor.s,fr.it flies,and *** compar.son,the study of human synapses has evolved significantly slower.mainly because of technical ***,thr.e novel methods allowing the analysis of molecular.mor.hological,and functional pr.per.ies of human synapses may expand our.knowledge of the human ***,we br.efly descr.be these methods,and evaluate how the infor.ation pr.vided by each unique appr.ach may contr.bute to the functional and anatomical analysis of the synaptic component of human br.in *** par.icular.using tissue fr.m cr.opr.ser.ed human br.ins,synaptic plasticity can be studied in isolated synaptosomes by fluor.scence analysis of single-synapse long-ter. potentiation（FASS-LTP）,and subpopulations of synapses can be thor.ughly assessed in the r.bbons of br.in tissue by ar.ay tomogr.phy（AT）.Cur.ently,it is also possible to quantify synaptic density in the living human br.in by positr.n emission tomogr.phy（PET）,using a novel synaptic ***,data pr.vided by FASS-LTP,AT,and PET may significantly contr.bute to the global under.tanding of synaptic str.ctur. and function in both healthy and diseased human br.ins,thus dir.ctly impacting tr.nslational r.sear.h.

关键词： fluor.scence analysis of single-synapse long-ter. potentiation ar.ay tomogr.phy positr.n emission tomogr.phy synaptosomes flow cytometr. micr.scopy [11C]UCB-J[(r.-1-((3-(11C-methyl-11C)pyr.din-4-yl)methyl)-4-(3 4 5-tr.fluor.phenyl)pyr.olidin-2-one]