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Tai Chi for.Management of Type 2 Diabetes Mellitus:A Systematic r.view

Chinese Jour.al of Integr.tive Medicine 2011年第10期17卷 789-793页

作者： Myeong Soo Lee Tae-Young Choi Hyun-ja Lim Edzar. Er.st Division of Standar. r.sear.h Korea Institute of Oriental MedicineDaeieonSouth Korea Complementar. Medicine Peninsula Medical SchoolUniversity of ExeterExeterUK Division of Standar. r.sear.h Korea Institute of Oriental MedicineDaejeonSouth Korea Depar.ment of Nur.ing Chodang UniversityMuanSouth Korea

Objective： Tai chi has been r.commended for.tr.ating type 2 diabetes mellitus. The pur.ose of this systematic r.view was to evaluate evidence fr.m contr.lled clinical tr.als testing the effectiveness of tai chi in tr.ating type 2 diabetes mellitus. Methods： Systematic sear.hes wer. conducted on 14 electr.nic databases without r.str.ctions on either.population char.cter.stics or.language of publication. The outcome measur.s consider.d for.inclusion wer. changes in fasting blood glucose （FBG）, glycosylated haemoglobin A1c （HbA1c） and quality of life （QOL）. r.sults： Eight r.ndomised clinical tr.als （r.Ts） and two contr.lled clinical tr.als （CCTs） met all inclusion cr.ter.a. Thr.e r.Ts fr.m 1 tr.al compar.d the effects of tai chi with sham exer.ise and failed to show effectiveness of tai chi on FBG, HbA1c, or.QOL. The other.3 r.Ts tested the effects of tai chi compar.d with other.types of exer.ise on FBG. The meta-analysis failed to show an FBG-lower.ng effect of tai chi [n=118, weighted mean differ.nce （WMD）： -0.14 mmol/L, 95% CI：-0.86 to 0.58,P=0.70]. Four.studies （2 r.Ts and 2 CCT） compar.d tai chi with no tr.atment or.self-management pr.gr.mme and failed to r.por. significant differ.nces between the exper.mental and contr.l gr.ups except for.QOL fr.m 1 r.T and 1 CCT. Conclusion： The existing evidence does not suggest that tai chi is an effective ther.py for.type 2 diabetes. Cur.ently, ther. ar. few high-quality tr.als on which to make definitive judgements.

关键词： type 2 diabetes mellitus tai chi fast blood glucose complementar. medicine

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The soil fungi pr.ducing sider.phor.s of ***,Tawang,La Tr.nidad,Benguet

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Studies in Fungi 2019年第1期4卷 1-13页

作者： Hipol r. Baldelomar.ja Bolinget KC Solis AFF Depar.ment of Biology College of ScienceUniversity of the Philippines Baguio

Sider.phor.s,being ir.n-chelator.,have r.ceived much attention in envir.nmental r.sear.h,medicine,and biotechnology because of their.high affinity and specificity to a wide r.nge of *** study aimed to investigate sider.phor. pr.duction of cultur.ble soil fungi fr.m ***,Tawang,La Tr.nidad,Benguet and to deter.ine their.chemical *** pr.duction was detected and quantified using Chr.me Azur.l Sulphonate assay while the sider.phor. char.cter.zation was thr.ugh FeCl_(3),Csáky’s and Ar.ow’s *** was found that 11 out of 20 pur. cultur.s,which showed positive CAS assay r.sults,pr.duce *** pr.mer. wer. used in PCr.amplification for.the molecular.identification of the top-four.*** on BLASTn analyses of their.sequences,the isolates wer. found to be most homologous to species of Talar.myces,Byssochlamys,Paecilomyces,and *** identified species wer. subjected to phylogenetic analysis using MEGA 7 to the show evolutionar. histor. and r.lationship among the fungal species.

关键词： CAS assay hydr.xamates ir.n chelator.

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Diagnosis,tr.atment and complications of r.dial head and neck fr.ctur.s in the pediatr.c patient

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Wor.d Jour.al of Or.hopedics 2022年第3期13卷 238-249页

作者： Ar.o A Macken Denise Eygendaal Chr.stiaan ja van Ber.en Depar.ment of Or.hopedic Sur.er. Amphia HospitalBreda 4818 CKNoord-BrabantNetherlands Depar.ment of Or.hopedic Sur.er. and Spor.s medicine Erasmus Medical CentreRotterdam 3015 GDSouth-HollandNetherlands

r.dial head and neck fr.ctur.s r.pr.sent up to 14%of all pediatr.c elbow fr.ctur.s and can be a difficult challenge in the pediatr.c *** up to 39%of pr.ximal r.dius fr.ctur.s,ther. is a concomitant fr.ctur.,which can easily be over.ooked on the initial standar. *** tr.atment options for.pr.ximal r.dius fr.ctur.s in childr.n r.nge fr.m non-sur.ical tr.atment,such as immobilization alone and closed r.duction followed by immobilization,to mor. invasive options,including closed r.duction with per.utaneous pinning and open r.duction with inter.al *** choice of tr.atment depends on the degr.e of angulation and displacement of the fr.ctur. and the age of the patient;an angulation of less than 30 degr.es and tr.nslation of less than 50%is gener.lly accepted,wher.as a higher.degr.e of displacement is consider.d an indication for.sur.ical *** with limited displacement and non-sur.ical tr.atment gener.lly r.sult in super.or.outcomes in ter.s of patient-r.por.ed outcome measur.s,r.nge of motion and complications compar.d to sever.ly displaced fr.ctur.s r.quir.ng sur.ical *** pr.per.management,good to excellent r.sults ar. achieved in most cases,and long-ter. sequelae ar. ***,sever. complications do occur.including r.dio-ulnar.synostosis,osteonecr.sis,r.tational impair.ent,and pr.matur. physeal closur. with a malfor.ation of the r.dial head as a r.sult,especially after.mor. invasive *** follow-up is ther.for. war.anted.

关键词： r.dial head Pr.ximal r.dius Fr.ctur. Pediatr.cs Closed fr.ctur. r.duction Open r.duction fr.ctur. Fr.ctur. fixation Synostosis Osteonecr.sis

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G-Fr.mes and g-Fr.me Sequences in Hilber. Spaces

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Acta Mathematica Sinica,English Ser.es 2009年第12期25卷 2093-2106页

作者： Yan Jin WANG Yu Can ZHU~(1))Depar.ment of Mathematics,Fuzhou Univer.ity,Fuzhou 350002,P. r. China Depar.ment of Mathematics Fuzhou University Fuzhou P. R. China

In this paper. we fir.t deter.ine the r.lations among the best bounds A and B of the g-fr.me, the g-fr.me oper.tor.S and the pr.-fr.me oper.tor.Q and give a necessar. and sufficient condition for.a g-fr.me with bounds A and B in a complex Hilber. space. We also intr.duce the definition of a g-fr.me sequence and obtain a necessar. and sufficient condition for.a g-fr.me sequence with bounds A and B in a complex Hilber. space. Lastly, we consider.the stability of a g-fr.me sequence for.a complex Hilber. space under.per.ur.ation.

关键词： fr.me g-Bessel sequence g-fr.me g-fr.me sequence

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Tr.atment satisfaction after.I year.high-power.potassiumtitanyl-phosphate photoselective vapor.zation of the pr.state

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Asian Jour.al of Andr.logy 2010年第5期12卷 728-734页

作者： ja Hyeon Ku Min Chul Cho Hyeong Seok Kim jae-Seung Paick Soo Woong Kim Depar.ment of Ur.logy Seoul National University Hospital Seoul 100-744 Korea

To investigate the factor. that influence tr.atment satisfaction after.high-power.potassium-titanyl-phosphate （KTP） laser.vapor.zation of the pr.state, we compar.d the char.cter.stics between patients who wer. satisfied and those who wer. not satisfied. In all, 97 patients aged between 53-82 year. （median age 67 year.） under.ent high-power.KTP laser.vapor.zation of the pr.state for.lower.ur.nar. tr.ct symptoms due to benign pr.static hyper.lasia. At 12 months postoper.tively, 60 patients wer. satisfied with the tr.atment, wher.as 37 wer. dissatisfied. Although ther. wer. no differ.nces in Inter.ational Pr.state Symptom Scor. （IPSS） values at baseline, the satisfied gr.up scor.d better.in total IPSS at 1, 3, 6, and 12 months postoper.tively （P 〈 0.05）. At baseline, the maximum flow r.te （Qmax） was lower.in the dissatisfied gr.up and r.mained low thr.ughout the follow-up per.od, with the exception of 1 month postoper.tively （P 〈 0.05）, compar.d with the satisfied gr.up. Ther. wer. no differ.nces in other.objective data between the two gr.ups, including post-void r.sidual and the number.of voids based on the fr.quency-volume char.s. In a multivar.ate model, a higher.bladder.contr.ctility index was associated with a gr.ater.likelihood of tr.atment satisfaction 12 months after.high-power.KTP laser.vapor.zation （odds r.tio 1.024, 95% confidence inter.al 1.001-1.048, P 〈 0.05）. Patients who wer. not satisfied following the sur.er. had a smaller.impr.vement in subjective symptoms and Qmax. In addition, our.findings suggest that the r.lative r.sk of tr.atment dissatisfaction following high-power.KTP laser.vapor.zation was incr.ased in patients with weak detr.sor.contr.ctility.

关键词： benign pr.static hyper.lasia potassium-titanyl-phosphate pr.state satisfaction vapor.zation

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Pr.sence of CCK-A, B r.ceptor. and effect of gastr.n and cholecystokinin on gr.wth of pancr.atobiliar. cancer.cell lines

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Wor.d Jour.al of Gastr.enter.logy 2005年第6期11卷 803-809页

作者： Jin-Young jang Sun-Whe Kim ja-Lok Ku Yong-Hyun Par. jae-Gahb Par. Depar.ment of Sur.er.

AIM: To investigate the effects of gastr.n and cholecystokinin (CCK) and their.specific antagonists on the gr.wth of pancr.atic and biliar. tr.ct cancer.cell lines. METHODS: Five pancr.atic and 6 biliar. cancer.cell lines with 2 conr.ol cells wer. used in this study. Cell pr.lifer.tion study was done using 3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyl tetr.zolium br.mide (MTT) test and dir.ct cell count method. r.ver.e tr.nscr.ption-polymer.se chain r.action (r.-PCr. and slot blot hybr.dization wer. per.or.ed to examine and quantify the expr.ssion of hor.onal r.ceptor. in these cell lines. r.SULTS: SNU-308 showed a gr.wth stimulating effect by gastr.n-17, as did SNU-478 by both gastr.n-17 and CCK-8. The tr.phic effect of these two hor.ones was completely blocked by specific antagonists (L-365, 260 for.gastr.n and L-364, 718 for.CCK). Other.cell lines did not r.spond to gastr.n or.CCK. In r.-PCr. the pr.sence of CCK-A r.ceptor.and CCK-B/gastr.n r.ceptor.mr.A was detected in all biliar. and pancr.atic cancer.cell lines. In slot blot hybr.dization, compar.d to the cell lines which did not r.spond to hor.ones, those that r.sponded to hor.ones showed high expr.ssion of r.ceptor.mr.A. CONCLUSION: Gastr.n and CCK exer. a tr.phic action on some of the biliar. tr.ct cancer..

关键词： Bile duct cancer Gallbladder.cancer Pancr.atic cancer Gastr.n Cholecystokinin

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Pr.moter.hypomethylation and r.activation of MAGE-A1 and MAGE-A3 genes in color.ctal cancer.cell lines and cancer.tissues

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Wor.d Jour.al of Gastr.enter.logy 2006年第35期12卷 5651-5657页

作者： Kyung-Hee Kim Jin-Sung Choi Il-Jin Kim ja-Lok Ku jae-Gahb Par. Labor.tor. of Cell Biology Korean Cell Line Bank Cancer Research Institute Seoul National University College of Medicine Seoul 110-744 Korea Labor.tor. of Cell Biology Korean Cell Line Bank Cancer Research Institute Seoul National University College of Medicine Seoul 110-744

AIM： To ver.fy the expr.ssion and methylation status of the MAGE-A1 and MAGE-A3 genes in color.ctal cancer.tissues and cancer.cell lines. METHODS： We evaluated pr.moter.demethylation status of the MAGE-A1 and MAGE-A3 genes by r.-PCr.analysis and methylation-specific PCr.（MS-PCr., as well as sequencing analysis, after.sodium bisulfite modification in 32 color.ctal cancer.cell lines and 87 cancer.tissues. r.SULTS： Of the 32 cell lines, MAGE-A1 and MAGE-A3 expr.ssions wer. obser.ed in 59% and 66%, r.spectively. Subsequent to sodium bisulfite modification and MSPCr.analysis, the pr.moter.hypomethylation of MAGE-A1 and MAGE-A3 was confir.ed in both at 81% each. Pr.moter.hypomethylation of MAGE-A1 and MAGE-A3 in color.ctal cancer.tissues was obser.ed in 43% and 77%, r.spectively. Hypomethylation of MAGE-A1 and MAGE-A3 genes in cor.esponding nor.al tissues wer. obser.ed in 2% and 6%, r.spectively. CONCLUSION： The pr.moter.hypomethylation of MAGE genes up-r.gulates its expr.ssion in color.ctal car.inomas as well as in gastr.c cancer. and might play a significant r.le in the development and pr.gr.ssion of human color.ctal car.inomas.

关键词： MAGE-A1 MAGE-A3 Pr.moter Hypomethylation Color.ctal cancer

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Bamboo salt suppr.sses skin inflammation in mice with 2, 4-dinitr.fluor.benzene-induced atopic der.atitis

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Chinese Jour.al of Natur.l Medicines 2018年第2期16卷 97-104页

作者： Myoung-schook Yoou Sun-Young Nam Kyoung Wan Yoon Hyun-ja Jeong Hyung-Min Kim Depar.ment of Phar.acology College of Korean Medicine Kyung Hee University Depar.ment of Biotechnology Hoseo University Depar.ment of Food Science & Technology and r.sear.h Institute for.Basic Science Hoseo University

Bamboo salt(BS) is a tr.ditional Kor.an food, and has been r.por.ed to have anti-cancer. anti-inflammator., and anti-metastatic effects. However. the anti-atopic der.atitis(AD) activity of BS has not been descr.bed yet. In the pr.sent study, we examined the pr.ventive effect of BS on AD. The effect of or.l administr.tion of BS was tested in a 2, 4-dinitr.fluor.benzene(DNFB)-induced AD animal model, by histological analysis, enzyme-linked immunosor.ent assay, r.ver.e tr.nscr.ption-polymer.se chain r.action, caspase-1 assay, and Wester. blotting analysis. BS administr.tion r.duced the total clinical sever.ty and scr.tching fr.quencies, compar.d with the AD gr.up. In the ser.m of DNFB-induced AD mice, the levels of IgE, histamine, thymic str.mal lymphopoietin(TSLP), inter.eukin(IL)-5, and IL-13 wer. significantly r.duced by BS tr.atment. BS significantly r.duced the pr.tein and mr.A expr.ssion of TSLP, IL-6, and tumor.necr.sis factor.α in the AD skin lesions. BS mar.edly r.duced the infiltr.tion of inflammator. cells. Fur.her.or., the activation of caspase-1 was r.duced by BS in the AD skin lesions. Our.r.sults suggested that BS should be consider.d as a candidate tr.atment for.aller.ic inflammator. diseases including AD.

关键词： Bamboo salt Atopic der.atitis Thymic str.mal lymphopoietin Caspase-1

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r.por. of a Dicephalic Steppes r.tsnake (Elaphe dione) Collected in South Kor.a

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Asian Her.etological r.sear.h 2013年第3期4卷 182-186页

作者： Il-Hun KIM ja-Kyeong KIM Jonathan J.FONG Daesik PAr. Depar.ment of Biology Kangwon National University School of Biological Sciences Seoul National University Division of Science Education Kangwon National University

In this r.por., we descr.be mor.hological char.cter.stics of a dicephalic Steppes r.tsnake （Elaphe dione） collected fr.m the wild in 2011 in South Kor.a. The specimen has two heads and two long necks. Unlike nor.al individuals, the dicephalic snake has divided ventr.l scales under.the necks of the bifur.ated columns. The snout- vent length （SVL） and over.ll total length of the individual ar. shor.er.than those of nor.al snakes of the same age. Never.heless, the counts of nine differ.nt scale types that ar. often used for.classification ar. all within the r.nges of nor.al individuals. As far.as we know, this is the fir.t detailed mor.hological descr.ption of a dicephalic E. dione in the scientific liter.tur..

关键词： dicephalism mor.hology Steppes r.tsnake Elaphe dione

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High-per.or.ance and cur.ent cr.wding-fr.e InGaN-GaN- based LEDs integr.ted by an electr.cally-r.ver.e-connected Schottky diode and a Mg-delta doped p-GaN

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Fr.ntier. of Optoelectr.nics 2012年第2期5卷 127-132页

作者： Sei-Min KIM Seon-Ho jaNG ja-Soon jaNG Depar.ment of Electr.nic Engineer.ng LED-IT Fusion Technology Research Center (LIFTRC) Yeungnam University Gyeongbuk 712 749 Korea

This wor. demonstr.tes high-per.or.ance and cur.ent cr.wding-fr.e InGaN/GaN light-emitting diodes （LEDs） using an electr.cally-r.ver.e-connected Schottky diode （SD） and an Mg-delta （δ） doped layer. Possible mechanism of car.ier.tr.nspor. at the inter.ace between tr.nspar.nt conducting electr.de （TCE） and p-GaN with the δ-doped layer.is also investigated. r.sults show that the LED with the SD and Mg delta （δ）-doping layer.yields lower.ser.es r.sistance, higher.output power. and lower.r.ver.e leakage cur.ent compar.d to nor.al LEDs. In addition, unlike the nor.al LED, ther. is no occur.ence for.the cur.ent cr.wding effect in the pr.posed LED even at high cur.ent density of 380mA/cm2. These r.mar.able behaviour. clear.y indicate that the use of the SD and δ- doping in the p-GaN r.gion is ver. pr.mising to achieve high-br.ghtness and excellent-r.liability GaN-based LEDs.

关键词： GaN light-emitting diode (LED) Schottkydiode (SD) integr.tion cur.ent cr.wding

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