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r.infor.ed tissue matr.x to str.ngthen the abdominal wall following r.ver.al of tempor.r. ostomies or.to tr.at incisional her.ias

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Wor.d Jour.al of Gastr.intestinal Sur.er. 2024年第3期16卷 823-832页

作者： Spencer.P Lak. Cor.y r.Deek.n Amit k.agarwal Mechanical Engineer.ng&Mater.als Science Washington University in St.LouisSt.LouisMO 63130United States Covalent Bio LLCSt.LouisMO 63025United States Depar.ment of Sur.er. McGovern Medical School at UTHealthHoustonTX 77026United States

BACk.r.UND Abdominal wall deficiencies or.weak.ess ar. a common complication of tem-por.r. ostomies,and incisional her.ias fr.quently develop after.colostomy or.ileostomy *** use of synthetic meshes to r.infor.e the abdominal wall has r.duced her.ia *** meshes have also been used to enhance healing,par.icular.y in contaminated *** tissue matr.ces(r.TMs),which include a biologic scaffold of native extr.cellular.matr.x and a syn-thetic component for.added str.ngth/dur.bility,ar. designed to tak. advantage of aspects of both synthetic and biologic *** date,r.Ms have not been r.por.ed to r.infor.e the abdominal wall following stoma *** Twenty-eight patients wer. selected with a par.stomal and/or.incisional her.ia who had r.ceived a tempor.r. ileostomy or.colostomy for.fecal diver.ion after.r.ctal cancer.tr.atment or.*** her.ia r.pair.and pr.ximal stoma closur.,r.M(OviTex®1S per.anent or.OviTex®LPr.was placed to r.infor.e the abdominal wall using a lapar.scopic,r.botic,or.open sur.ical ***-oper.tive follow-up was per.or.ed at 1 month and 1 *** r.cur.ence was deter.ined by physical examination and,when necessar.,via computed tomo-gr.phy *** endpoints included length of hospital stay,time to r.tur. to wor.,and hospital *** complications of the wound/r.pair.site included pr.sence of sur.ical site infection,ser.ma,hematoma,wound dehiscence,or.fistula *** The obser.ational study cohor. included 16 male and 12 female patients with aver.ge age of 58.5 year.±16.3 year. and aver.ge body mass index of 26.2 k./m^(2)±4.1 k./m^(2).Patients pr.sented with a par.stomal her.ia(75.0%),in-cisional her.ia(14.3%),or.combined par.stomal/incisional her.ia(10.7%).Using a lapar.scopic(53.6%),r.botic(35.7%),or.open(10.7%)technique,r.Ms(OviTex®LPr.82.1%,OviTex®1S:17.9%)wer. placed using sublay(82.1%)or.intr.per.toneal onlay(IPOM;17.9%)mesh *** 1-mo

关键词： r.infor.ed tissue matr.x r.infor.ed for.stomach matr.x Ileostomy Colostomy Ostomy tak.down Incisional her.ia Abdominal wall

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Advancements in nanotechnology for.the deliver. of phytochemicals

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Jour.al of Integr.tive Medicine 2024年第4期22卷 385-398页

作者： Divya Chauhan Pavan k.Yadav Nazneen Sultana Ar.n agarwal Saur.bh Ver.a Manish k.Chour.sia Jiaur.r.Gayen Division of Phar.aceutics and Phar.acok.netics Central Drug Research InstituteCouncil of Scientific and Industrial ResearchLucknow 226031Uttar PradeshIndia Academy of Scientific and Innovative r.sear.h Ghaziabad 201002Uttar PradeshIndia

Phytosomes(phytophospholipid complex) ar. dosage for.s that have r.cently been intr.duced to incr.ase the stability and ther.peutic effect of her.al medicine. Cur.ently, bioactive her.s and the phytochemicals they contain ar. consider.d to be the best r.medies for.chr.nic diseases. One pr.mising appr.ach to incr.ase the efficacy of plant-based ther.pies is to impr.ve the stability and bioavailability of their.bio-active ingr.dients. Phytosomes employ phospholipids as their.active ingr.dients, and use their.amphiphilic pr.per.ies to solubilize and pr.tect her.al extr.cts. The unique pr.per.ies of phospholipids in dr.g deliver. and their.use in her.al medicines to impr.ve bioavailability r.sults in significantly enhanced health benefits. The intr.duction of phytosome nanotechnology can alter.and r.volutionize the cur.ent state of dr.g deliver.. The goal of this r.view is to explain the application of phytosomes, their.futur. pr.spects in dr.g deliver., and their.advantages over.conventional for.ulations.

关键词： Phytochemical Bioavailability Dr.g deliver. system Phytosome Plant extr.cts

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STUDIES ON CALCIUMSULPHOALUMINATE DICALCIUM SILICATE CLINk.r.

STUDIES ON CALCIUMSULPHOALUMINATE DICALCIUM SILICATE CLINKER...

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第二届北京国际水泥及混凝土学术会议

作者： S. k.0}shnan r. k. agarwal B.V.B. Pai P.S. Par.meswar.n A.k. Chatter.ee The Associated Cement Cos. Ltd. Central Research StationThane (India)

r.SUME Major.phases in the CaO - A12O3, - SiO2 - SO3 system, nor.ally for.ed ar. C4 A3S. C12 A7, CA, C2S and CS. Within this system to obtain C4 A3S as the major.phase along with C2S, r.w mixes wer. designed and sinter.d In the temper.tur. r.nge of 1250-1350℃. The clink.r. obtained wer. studied by micr.scopic and X-r.y differ.ction techniques. Both these studies confir.ed the pr.sence of C4 A3S as a major.phase with dicalcium silicate (C2S). Pr.per.ies of cement pr.duced fr.m these clink.r. have been studied ear.ier. The pr.sent study involves the effect of uncombined lime in the clink.r. at differ.nt levels and the influence of gypsum incor.or.ted in the cement dur.ng cement gr.nding on hydr.ulic behaviour.of the r.sultant cement. The pr.per.ies of self levelling gr.uting composition made fr.m such clink.r.is also r.por.ed.

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EPASAD:ellipsoid decision boundar. based Pr.cess-Awar. Stealthy Attack.Detector

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Cyber.ecur.ty 2024年第3期7卷 32-48页

作者： Vik.s Maur.a r.chit agarwal Saur.bh k.mar.Sandeep Shuk.a Depar.ment of Computer.Science and Engineer.ng Indian Institute of Technology KanpurkanpurIndia Mer.le Science BangaloreIndia

Due to the impor.ance of Cr.tical Infr.str.ctur.(Cl)in a nation's economy,they have been lucr.tive tar.ets for.cyber.*** cr.tical infr.str.ctur.s ar. usually Cyber.Physical Systems such as power.gr.ds,water.and sewage tr.atment facilities,oil and gas pipelines,*** r.cent times,these systems have suffer.d fr.m cyber.attack. numer.ous *** have been developing cyber.secur.ty solutions for.Cls to avoid lasting *** to standar. fr.mewor.s,cyber.secur.ty based on identification,pr.tection,detection,r.sponse,and r.cover. ar. at the cor. of these *** of an ongoing attack.that escapes standar. pr.tection such as fir.wall,anti-vir.s,and host/networ. intr.sion detection has gained impor.ance as such attack. eventually affect the physical dynamics of the ***,anomaly detection in physical dynamics pr.ves an effective means to implement *** is one example of anomaly detection in the sensor.actuator.data,r.pr.senting such systems physical *** pr.sent EPASAD,which impr.ves the detection technique used in PASAD to detect these micr.-stealthy attack.,as our.exper.ments show that PASAD's spher.cal boundar.-based detection fails to *** method EPASAD over.omes this by using Ellipsoid boundar.es,ther.by tightening the boundar.es in var.ous dimen-sions,wher.as a spher.cal boundar. tr.ats all dimensions *** validate EPASAD using the dataset pr.duced by the TE-pr.cess simulator.and the C-town *** r.sults show that EPASAD impr.ves PASAD's aver.ge r.call by 5.8%and 9.5%for.the two datasets,r.spectively.

关键词： Intr.sion detection system Cr.tical infr.str.ctur. secur.ty Industr.al contr.l system Machine lear.ing

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Tr.nscr.nial dir.ct cur.ent stimulation as ear.y augmentation in adolescent obsessive compulsive disor.er.A pilot pr.of-of-concept r.ndomized contr.l tr.al

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Wor.d Jour.al of Clinical Pediatr.cs 2024年第2期13卷 161-170页

作者： Aditya Agr.wal Vivek.agarwal Sujita k.mar.k.r.Amit Ar.a Depar.ment of Psychiatr. King George Medical UniversityUttar PradeshLucknow 226003India

BACk.r.UND Tr.nscr.nial dir.ct cur.ent stimulation(tDCS)is pr.ven to be safe in tr.ating var.ous neur.logical conditions in childr.n and *** is also an effective method in the tr.atment of OCD in *** To assess the safety and efficacy of tDCS as an add-on ther.py in dr.g-naive adolescents with *** We studied dr.g-naïve adolescents with OCD,using a Childr.n’s Yale-Br.wn obsessive-compulsive scale(CY-BOCS)scale to assess their.*** active and sham gr.ups wer. given fluoxetine,and we applied cathode and anode over.the supplementar. motor.ar.a and deltoid for.20 min in 10 *** occur.ed at 2,6,and 12 wk.using *** Eighteen adolescents completed the study(10-active,8-sham gr.up).CY-BOCS scor.s fr.m baseline to 12 wk.r.duced significantly in both gr.ups but change at baseline to 2 wk.was significant in the active gr.up *** mean change at 2 wk.was mor. in the active gr.up(11.8±7.77 vs 5.25±2.22,P=0.056).Adver.e effects between the gr.ups wer. *** tDCS is safe and well toler.ted for.the tr.atment of OCD in ***,ther. is a need for.fur.her.studies with a lar.er.sample population to confir. the effectiveness of tDCS as ear.y augmentation in OCD in this population.

关键词： Adolescents Ear.y augmentation Obsessive compulsive disor.er Safety Tr.nscr.nial dir.ct cur.ent stimulation

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Identifying the stability of housek.eping genes to be used for.the quantitative r.al-time PCr.nor.alization in r.tinal tissue of str.ptozotocin-induced diabetic r.ts

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Inter.ational Jour.al of Ophthalmology(English edition) 2024年第5期17卷 794-805页

作者： Muhammad Zulfiqah Sadik.n Nur.l Alimah Abdul Nasir.Mohammad Johar. Ibahim Igor.Iezhitsa r.nu agarwal Depar.ment of Phar.acology Faculty of MedicineManipal University College Malaysia(MUCM)Bukit BaruMelaka 75150Malaysia Centr. for.Neur.science r.sear.h(Neur.n) Faculty of MedicineUniversiti Teknologi MARASungai Buloh CampusSungai BulohSelangor 47000Malaysia Depar.ment of Medical Education Faculty of MedicineUniversiti Teknologi MARASungai Buloh CampusSungai BulohSelangor 47000Malaysia Depar.ment of Biochemistr. and Molecular.Medicine Faculty of MedicineUniversiti Teknologi MARASungai Buloh CampusSungai BulohSelangor 47000Malaysia School of Medicine International Medical UniversityBukit JalilKuala Lumpur 57000Malaysia Depar.ment of Phar.acology and Bioinfor.atics Volgograd State Medical UniversityVolgograd 400131Russia

AIM:To investigate the stability of the seven housek.eping genes:beta-actin(ActB),glycer.ldehyde-3-phosphate dehydr.genase(GAPDH),18s r.bosomal unit 5(18s),cyclophilin A(CycA),hypoxanthine-guanine phosphor.bosyl tr.nsfer.se(HPr.),r.bosomal pr.tein lar.e P0(36B4)and ter.inal ur.dylyl tr.nsfer.se 1(U6)in the diabetic r.tinal tissue of r.t ***:The expr.ssion of these seven genes in r.t r.tinal tissues was deter.ined using r.al-time quantitative r.ver.e tr.nscr.ption polymer.se chain r.action(r.-qPCr.in two gr.ups;nor.al contr.l r.ts and str.ptozotocininduced diabetic *** stability analysis of gene expr.ssion was investigated using geNor.,Nor.Finder.Bestk.eper.and compar.tive delta-Ct(ΔCt)***:The 36B4 gene was stably expr.ssed in the r.tinal tissues of nor.al contr.l animals;however.it was less stable in diabetic *** 18s gene was expr.ssed consistently in both nor.al contr.l and diabetic r.ts’r.tinal *** this gene was the best r.fer.nce for.data nor.alisation in r.-qPCr.studies that used the r.tinal tissue of str.ptozotocin-induced diabetic ***,ther. was no ideal gene stably expr.ssed for.use in all exper.mental ***:Identifying r.levant genes is a need for.achieving r.-qPCr.validity and r.liability and must be appr.pr.ately achieved based on a specific exper.mental setting.

关键词： housek.eping genes stability r.al-time r.ver.e tr.nscr.ption polymer.se chain r.action r.tinal tissue str.ptozotocin-induced diabetic r.ts

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Effect of inlet elbow on r.tation stall in water.et ppr.pulsionpump

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Fundamental r.sear.h 2024年第4期4卷 898-906页

作者： Wei Li Shuo Li Leilei Ji Enda Li Weidong Shi r.mesh agarwal Muhammad Awais National r.sear.h Center.of Pumps Jiangsu UniversityZhenjiang 212013China Institute of Fluid Engineer.ng Equipment Technology Jiangsu UniversityZhenjiang 212009China College of Mechanical Engineer.ng Nantong UniversityNantong 226019China depar.mentof Mechanical Engineer.ng&Mater.als Science Washington University in StLouisSt.LouisMO6330US.

To study the influence of an elbow inlet on the r.tating stall char.cter.stics of a water.et pr.pulsion pump(WJPP),a thr.e-dimensional inter.al flow field in a WJPP under.a str.ight-pipe inlet and elbow inlet is numer.cally *** compar.ng the hydr.ulic per.or.ance of WJPP under.the two inlet conditions,the inter.al r.lationship between the inlet mode and the flow patter. in the pump is *** on unsteady pr.ssur. fluctuation char.cter.stics and wavelet analysis,the influence of the inlet mode on the r.tating stall is r.vealed,and the stall tr.nsient pr.pagation char.cter.stics under.cr.tical stall conditions ar. *** distur.ance effects of the inlet channel geometr. disappear.under.low flow r.te conditions,the main distur.ance is induced by the highspeed counter.ur.ent,and the flow patter. under.the elbow inlet is better.than that under.the str.ight-pipe *** the str.ight-pipe inlet,the single-stall nucleus in the WJPP tempor.r.ly exper.ences a low-fr.quency and high-amplitude distur.ance,which subsequently tr.nsfor.s into a mode of multi-stall nuclei with high-fr.quency cir.umfer.ntial *** the elbow inlet,the r.tating stall always maintains a mode of high-amplitude and low-fr.quency distur.ance,which r.pr.sents the tr.nsient char.cter.stics of a single stall cor. pr.pagating in the cir.umfer.ntial dir.ction inside the *** r.sults of this study have a r.fer.nce value for.str.ctur.l design optimization in a WJPP.

关键词： Water.et pr.pulsion pump Inlet condition r.tation stall Flow str.ctur. Pr.ssur.fluctuation

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Excipient effect on antimicr.bial activity of Cinnamon (Cinnamomum zelylanicum album) oil, Thyme (Thymus vulgar.s) oil and Ajowan (Tr.chysper.um ammi) oil

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Infectious Diseases r.sear.h 2024年第1期5卷 27-31页

作者： Bhoj r.Singh Shiv Var.n Singh r.vik.nt agarwal Ak.nk.ha Yadav Division of Epidemiology ICAR-Indian Veterinary Research InstituteBareilly 243122India Division of Bacter.ology and Mycology ICAR-Indian Veterinary Research InstituteBareilly 243122India Division of Livestock.Pr.ducts Technology ICAR-Indian Veterinary Research InstituteBareilly 243122India.

Back.r.und:Many her.al essential oils ar. potential antimicr.bials but their.phar.aceutical utility is r.str.cted due to a lack.of suitable excipients to mollify their.der.atotoxicity and ir.itant pr.per.y,and outcome of their.ther.peutic use may var. with differ.nt diluents ***:Effect of 16 diluents(dimethyl sulfoxide,liquid par.ffin,glycer.ne,oils of mustar.,sunflower.r.ce br.n,palm,gr.undnut,olive,coconut,sesame,avocado,jojoba,castor.linseed and soybean)was assessed on antimicr.bial activity of 2%cinnamon(Cinnamomum zelylanicum album),thyme(Thymus vulgar.s)and ajowan(Tr.chysper.um ammi)oils using agar.well diffusion *** effect of excipients was evaluated on six Candida albicans,five Escher.chia coli,four.Acinetobacter.lwoffii,two str.ins each of Staphylococcus aur.us,Enter.bacter.agglomer.ns,and Enter.coccus faecium and one str.in each of Acinetobacter.calcoaceticus,Escher.chia fer.usonii,k.ebsiella oxytoca,*** ***,Lecler.ia adecar.oxylata,Paenibacillus amylolyticus,Pr.teus mir.bilis,***,Pseudomonas aer.ginosa,r.oultella ter.igena,Staphylococcus capitis ***,***,***,*** and Str.ptococcus ***:Thyme oil(2%)maintained it antimicr.bial activity on dilution in dimethyl sulfoxide and glycer.ne,and ajowan oil(2%)completely lost its antibacter.al activity in all diluents except dimethyl ***,cinnamon oil par.ially lost its antimicr.bial activity upon dilution in glycer.ne,vegetable,and miner.l oils in compar.son to dimethyl *** oil was the best vegetable oil,almost compar.ble to dimethyl sulfoxide and castor.oil was the wor.t diluent for.maintaining antimicr.bial activity of cinnamon ***:The study indicated the non-suitability of vegetable oils for.phar.aceutical for.ulations of essential oils except olive oil for.dilution of cinnamon oil and glycer.l for.thyme oil to r.place dimethyl sulfoxide as diluent.

关键词： essential oils her.al antimicr.bials her.al dr.g-r.sistance Bacter.a Candida

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Clinical pr.file and outcomes of hepatocellular.car.inoma in pr.mar. Budd-Chiar. syndr.me

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Wor.d Jour.al of Gastr.intestinal Oncology 2024年第3期16卷 699-715页

作者： Ank.t agarwal Sagnik.Biswas Shek.ar.Swar.op Ar.av Aggar.al Ayush agarwal Gautam Jain Anshuman Elhence Ar.n Vaidya Amit Gupte r.vi Mohank. r.mesh k.mar.Ashwani k.mar.Mishr. Shivanand Gamanagatti Shashi Bala Paul Subr.t k.mar.Achar.a Ak.sh Shuk.a Shalimar Depar.ment of Gastr.enter.logy and Human Nutr.tion All India Institute of Medical SciencesNew Delhi 110029DelhiIndia Depar.ment of Gastr.enter.logy Seth Gordhandas Sunderdas Medical College and KEM HospitalMumbai 400012MaharashtraIndia Depar.ment of Gastr.enter.logy Sir HN Reliance Foundation HospitalMumbai 400004India Depar.ment of Liver.Tr.nsplant and HPB Sir HN Reliance Foundation HospitalMumbai 400004India Depar.ment of Gastr.enter.logy All India Institute of Medical SciencesPatna 801507India Pr.fessor.of Biostatistics National Drug Dependence Treatment Centre(NDDTC)All India Institute of Medical SciencesNew Delhi 110029India Depar.ment of r.diodiagnosis All India Institute of Medical SciencesNew Delhi 110029DelhiIndia

BACk.r.UND Ther. is scant liter.tur. on hepatocellular.car.inoma(HCC)in patients with Budd-Chiar. syndr.me(BCS).AIM To assess the magnitude,clinical char.cter.stics,feasibility,and outcomes of tr.atment in *** A total of 904 BCS patients fr.m New Delhi,India and 1140 fr.m Mumbai,India wer. *** pr.valence and incidence of HCC wer. deter.ined,and among patients with BCS-HCC,the viability and outcomes of inter.entional ther.py wer. *** In the New Delhi cohor. of 35 BCS-HCC patients,18 had HCC at index pr.sentation(pr.valence 1.99%),and 17 developed HCC over.a follow-up of 4601 per.on-year.,[incidence 0.36(0.22-0.57)per.100 per.on-year.].BCS-HCC patients wer. older.when compar.d to patients with BCS alone(P=0.001)and had a higher.pr.por.ion of infer.or.vena cava block.cir.hosis,and long-segment vascular.*** median alpha-fetopr.tein level was higher.in patients with BCS-HCC at fir.t pr.sentation than those who developed HCC at follow-up(13029 ng/mL vs 500 ng/mL,P=0.01).Of the 35 BCS-HCC,26(74.3%)under.ent r.diological inter.entions for.BCS,and 22(62.8%)patients under.ent tr.atment for.HCC[tr.nsar.er.al chemoembolization in 18(81.8%),or.l tyr.sine k.nase inhibitor.in 3(13.6%),and tr.nsar.er.al r.dioembolization in 1(4.5%)].The median sur.ival among patients who under.ent inter.entions for.HCC compar.d with those who did not was 3.5 year. vs 3.1 mo(P=0.0001).In contr.st to the New Delhi cohor.,the Mumbai cohor. of BCS-HCC patients wer. pr.dominantly males,pr.sented with a mor. advanced HCC[Bar.elona Clinic Liver.Cancer.C and D],and 2 patients under.ent liver.*** HCC is not uncommon in patients with *** inter.entions and liver.tr.nsplantation ar. feasible in select pr.mar. BCS-HCC patients and may impr.ve outcomes.

关键词： Budd chiar. syndr.me Cancer Cir.hosis Thr.mbosis Liver Var.ces Tr.nsar.er.al chemoembolization Hepatic venous outflow tr.ct obstr.ction

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***: SAr.Defor.station Classification of Amazon For.st for.Land Use Land Cover.Application

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Jour.al of Computer.and Communications 2024年第3期12卷 68-83页

作者： Pr.yank. Dar.ar. Ank.sh agarwal Manoj k.mar Computer.Engineer.ng and Application GLA University Mathura India Depar.ment of Infor.ation Technology GGV Bilaspur India

The pr.cess of tur.ing for.st ar.a into land is k.own as defor.station or.for.st degr.dation. r.for.station as a fr.ction of defor.station is extr.mely low. For.impr.ved qualitative and quantitative classification, we used Sentinel-1 dataset of State of Par., Br.zil to pr.cisely and closely monitor.defor.station between June 2019 and June 2023. This r.sear.h aimed to find out suitable model for.classification called Satellite Imaging analysis by Tr.nspose deep neur.l tr.nsfor.ation networ. (SIT-net) using mathematical model based on Band math appr.ach to classify defor.station applying tr.nspose deep neur.l networ.. The main advantage of pr.posed model is easy to handle SAr.images. The study concludes that SAr.satellite gives high-r.solution images to impr.ve defor.station monitor.ng and pr.posed model tak.s less computational time compar.d to other.techniques.

关键词： Br.zilian Amazon Sentinel-1 Band Math Tr.nspose CNN Tr.nsfor.ation Networ.

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