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Jour.al of r.r. Ear.hs 2016年第1期34卷 21-29页

作者：廖侹乔刘宏 r. hussin Z. IBr.HIM K. DEr.MAN H.O. LINTANG W.N.W SHAMSUr. Phosphor.r.sear.h Gr.up Department of Physics Faculty of Seience Universiti Teknologi Malaysia Skudai 81310 Johor Malaysia State Key Labor.tor. of Cr.stal Mater.als Shandong University Jinan 250100 China Catalytic Science and Technology r.sear.h Gr.up Ibnu Sina Institute for Fundamental Science Studies Universiti Teknologi Malaysia Skudai 81310 Johor Malaysia

A ser.es of Eu3＋ and Dy3＋ doped/co-doped as well as un-doped BaB2Si2Os phosphor. wer. synthesized via solid state r.action method. The PL r.sult showed typical blue and gr.en emission fr.m Dy3＋ and r.d emission fr.m Eu3＋. The f-f tr.nsitions in- volving the lanthanide ions along with dopant site occupancy wer. discussed thor.ughly. Phonon assisted ener.y tr.nsfer.pr.cess was obser.ed fr.m Eu3＋ to Dy3＋, which enhanced the emissions of Dy3＋. Combinations of the emissions fr.m Eu3＋ and Dy3＋ showed a possible white to r.d tuneable emission on the CIE diagr.m. The white war.th emissions of the phosphor.wer. r.vealed to be ad- justable thr.ugh designing the dopant concentr.tion and excitation wavelengths. An unusual ener.y tr.nsfer.that or.ginated fr.m Eu3＋ to Dy3＋ was also discover.d and the ener.y tr.nsfer.mechanism was discussed. Pr.posed ener.y tr.nsfer.mechanism was investigated using luminescence decay lifetime. All the phosphor.exhibited efficient excitation in the UV r.nge which matched well with the emissions fr.m GaN-based LED chips. This pr.sented the BaB2Si208 phosphor.as a pr.mising candidate for.white LED applications. The effects of doping on the str.ctur.l pr.per.ies and the optical band gap of BaB2Si208 phosphor.wer. also discussed in this study.

关键词： BaB2Si2O8:Eu3+/Dy3+ phosphor ener.y tr.nsfer r.r. ear.hs

Photoluminescence and ther.oluminescence pr.per.ies of SnO_2 nanopar.icles embedded in Li_2O-K_2O-B_2O_3 with Cu-doping

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Chinese Optics Letter. 2013年第9期11卷 1-4页

作者： Haydar.Aboud H. Wagir.n r. hussin Saad Saber.M. A. Saeed Depar.ment of Physics Faculty of ScienceUniversiti Teknologi Malaysia Baghdad College of Economic Sciences Univer.ity

Cu-doped bor.te glass co-doped with SnO2nanopar.icles is fabr.cated by melt *** str.ctur. and mor.hology of the samples ar. examined by X-r.y diffr.ction and field emission scanning electr.n ***-conver.ion enhancement is obser.ed in the photoluminescence（PL） and ther.oluminescence（TL） intensities of the *** emission spectr. ar. identified in the blue and gr.en r.gions,and a four.old incr.ase in emission intensity may be obser.ed in the pr.sence of embedded *** glow cur.e is r.cor.ed at 215 C,and four.old incr.ases in TL intensity ar. obtained by addition of 0.1 mol% SnO2nanopar.icles to the *** TL r.sponses of the samples ar. obser.ed in the ener.y r.nge of 15-100 *** ener.y levels gr.ater.than;.1 MeV,however.flat r.sponses ar. *** activation ener.y and fr.quency factor.of the second-or.er.kinetic r.action ar. calculated by the peak shape method.

关键词： SnO Photoluminescence and ther.oluminescence pr.per.ies of SnO2 nanopar.icles embedded in Li2O-K2O-B2O3 with Cu-doping Cu Li

Coar.e to Fine: The r.le of Sever. Plastic Defor.ation in Advancing Titanium-Based Medical Implants - A Compr.hensive r.view

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Jour.al of Wuhan Univer.ity of Technology(Mater.als Science) 2025年第1期40卷 295-306页

作者： Dr.gana r.Mihajlović Bojan I Međo Ivana Lj Cvijović-Alagić Veljko r.Djokić Faculty of Technology and Metallur.y University of BelgradeKarnegijeva 411120 BelgradeSerbia Vinča Institute of Nuclear.Sci-ences-National Institute of the r.public of Ser.ia University of Belgrade11001BeogradSerbia Innovation Centr. of the Faculty of Technology and Metallur.y Karnegijeva 411120 BelgradeSerbia

This paper.descr.bes sever. plastic defor.ation(SPD)pr.cedur.s,which ar. utilized to for. an ultr.fine-gr.ined str.ctur. in metallic *** the SPD pr.cess,a solid mater.al sample is subjected to ver. high loads without a significant change in sample *** the pr.sent wor.,the high-pr.ssur. tor.ion(HPT)pr.cess,as one of the SPD techniques,which achieves a high degr.e of defor.ation and ensur.s r.finement of the micr.str.ctur.,will be discussed in mor. *** that gr.in size contr.l is accepted as a method to obtain mater.als with desir.d char.cter.stics,an over.iew of the pr.per.ies of ultr.fine-gr.ined titanium-based biomater.als to be used in medicine is ***,par.icular.attention is dedicated to the influences of HPT pr.cess par.meter.,pr.mar.ly hydr.static pr.ssur.,and number.of r.volutions dur.ng tor.ion,on the gr.in size and physical and mechanical char.cter.stics(modulus of elasticity,micr.har.ness,and tensile pr.per.ies),cor.osion r.sistance,and biocompatibility of the titanium-based biomater.als.A r.view of the liter.tur. indicates that titanium-based mater.als obtained by the SPD pr.cess show impr.ved mechanical and physical pr.per.ies without losing biocompatibility and cor.osion r.sistance,which suggests that these methods of obtaining implants ar. something that should be fur.her.developed in the futur..

关键词： high-pr.ssur. tor.ion pr.cess ultr.fine-gr.ined titanium-based mater.als electr.chemical anodization physical pr.per.ies mechanical pr.per.ies

Emer.ing potential of pr.gr.nulin-dependent Sor.S2 signaling in healthy and diseased ner.ous systems

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Neur.l r.gener.tion r.sear.h 2025年第9期20卷 2591-2593页

作者： Alena Salasova Ander. Nykjær Danish r.sear.h Institute of Tr.nslational Neur.science DANDr.TE-Nor.ic EMBL Par.ner.hip for.Molecular.Medicine and Centre of Excellence PROMEMODepartment of BiomedicineAarhus UniversityAarhusDenmark

The for.ation of the mammalian ner.ous system and its matur.tion into sensor.,motor.cognitive,and behavior.l cir.uits is a complex pr.cess that begins dur.ng ear.y embr.ogenesis and lasts until young *** neur.developm... 详细信息

关键词： pr.gr jointly CS2

Effects of Mg substitution on the str.ctur.l and magnetic pr.per.ies of Co0.5Ni（0.5-x）MgxFe2O4 nanopar.icle fer.ites

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Chinese Physics B 2016年第4期25卷 358-364页

作者： r.M r.snan Z Othaman r.hussin Ali A Ati Alir.za Samavati Shadab Dabagh samad Zar. Centr. for.Sustainable Nanomater.als Ibnu Sina Institute for Scientific and Industrial Research Universiti Teknologi Malaysia 81310 Skudai Johor Bahru Malaysia

In this study, nanocr.stalline Co-Ni-Mg fer.ite powder. with composition Coo.5Nio.5-xMgxFe2O4 ar. successfully synthesized by the co-pr.cipitation method. A systematic investigation on the str.ctur.l, mor.hological and magnetic pr.per.ies of un-doped and Mg-doped Co-Ni fer.ite nanopar.icles is car.ied out. The pr.par.d samples ar. char.cter.zed using x-r.y diffr.ction （Xr.） analysis, Four.er.tr.nsfor. infr.r.d spectr.scopy （FTIr., field emission scanning electr.n micr.scopy （FESEM）, and vibr.ting sample magnetometr. （VSM）. The Xr. analyses of the synthesized samples confir. the for.ation of single-phase cubic spinel str.ctur.s with cr.stallite sizes in a r.nge of - 32 nm to - 36 nm. The lat- tice constant incr.ases with incr.asing Mg content. FESEM images show that the synthesized samples ar. homogeneous with a unifor.ly distr.buted gr.in. The r.sults of Ir.spectr.scopy analysis indicate the for.ation of functional gr.ups of spinel fer.ite in the co-pr.cipitation pr.cess. By incr.asing Mg2- substitution, r.om temper.tur. magnetic measur.ment shows that maximum magnetization and coer.ivity incr.ase fr.m - 57.35 emu/g to - 61.49 emu/g and - 603.26 Oe to 684.11 Oe （l Oe = 79.5775 A.m-l）, r.spectively. The higher.values of magnetization Ms and Mr.suggest that the opti- mum composition is Co0.5Ni0.4Mg0.1Fe204 that can be applied to high-density r.cor.ing media and micr.wave devices.

关键词： co-pr.cipitation magnetic mater.als spinel fer.ite magnetic pr.per.ies

Secur.ty Str.tegy of Digital Medical Contents Based on Blockchain in Gener.tive AI Model

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Computer., Mater.als & Continua 2025年第1期82卷 259-278页

作者： Hoon Ko Mar.k r.Ogiela Division of Computer.Science and Engineer.ng Sunmoon UniversityAsan31460Republic of Korea AGH Univer.ity of Kr.kow Cryptography and Cognitive Informatics LaboratoryKrakow30-059Poland

This study pr.sents an innovative appr.ach to enhancing the secur.ty of visual medical data in the gener.tive AI envir.nment thr.ugh the integr.tion of blockchain *** combining the str.ngths of blockchain and gener.tive AI,the r.sear.h team aimed to addr.ss the timely challenge of safeguar.ing visual medical *** par.icipating r.sear.her. conducted a compr.hensive analysis,examining the vulner.bilities of medical AI ser.ices,per.onal infor.ation pr.tection issues,and over.ll secur.ty *** multi faceted explor.tion led to an indepth evaluation of the model’s per.or.ance and ***,the cor.elation between accur.cy,detection r.te,and er.or.r.te was *** analysis r.vealed insights into the model’s str.ngths and limitations,while the consider.tion of standar. deviation shed light on the model’s stability and per.or.ance *** study pr.posed pr.ctical impr.vements,emphasizing the r.duction of false negatives to enhance detection r.te and lever.ging blockchain technology to ensur. visual data integr.ty in medical *** blockchain to gener.tive AI-cr.ated medical content addr.sses key per.onal infor.ation pr.tection *** utilizing the distr.buted ledger.system of blockchain,the r.sear.h team aimed to pr.tect the pr.vacy and integr.ty of medical data especially medical *** appr.ach not only enhances secur.ty but also enables tr.nspar.nt and tamper.r.of ***,the use of gener.tive AI models ensur.s the cr.ation of novel medical content without compr.mising per.onal infor.ation,fur.her.safeguar.ing patient *** conclusion,this study showcases the potential of blockchain-based solutions in the medical field,par.icular.y in secur.ng sensitive medical data and pr.tecting patient *** pr.posed appr.ach,combining blockchain and gener.tive AI,offer. a pr.mising dir.ction towar. mor. r.bust and secur. medical content *** r.sear.h and advancements

关键词： Digitalmedical content medical diagnostic visualization secur.ty analysis gener.tiveAI blockchain vulner.bility patter. r.cognition

Antisense oligonucleotides pr.vide optimism to the ther.peutic landscape for.tauopathies

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Neur.l r.gener.tion r.sear.h 2025年第3期20卷 803-804页

作者： Glenn A.Har.is Laur.n r.Hir.chfeld r.inwater.Char.table Foundation Fort WorthTXUSA

Tauopathies ar. a gr.up of neur.degener.tive diseases char.cter.zed by abnor.al metabolism of the misfolded tau pr.tein. Tau is encoded by the micr.tubule-associated pr.tein tau gene(MAPT) and can be classified as either.3-r.peat(3r. or.4-r.peat(4r. based on the number.of r.peat domains fr.m alter.ative splicing of exon 10 of the MAPT gene.

关键词： tau metabolism diseases

Machine Lear.ing Techniques in Pr.dicting Hot Defor.ation Behavior.of Metallic Mater.als

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Computer.Modeling in Engineer.ng & Sciences 2025年第1期142卷 713-732页

作者： Petr.Opela Josef Walek Jar.mír.Kopecek Depar.ment of Metallur.ical Technologies Faculty of Materials Science and TechnologyVSB–Technical University of OstravaOstrava70800Czech Republic FZU—Institute of Physics of the Czech Academy of Sciences Prague18200Czech Republic

In engineer.ng pr.ctice,it is often necessar. to deter.ine functional r.lationships between dependent and independent *** r.lationships can be highly nonlinear.and classical r.gr.ssion appr.aches cannot always pr.vide sufficiently r.liable ***,Machine Lear.ing(ML)techniques,which offer.advanced r.gr.ssion tools to addr.ss complicated engineer.ng issues,have been developed and widely *** study investigates the selected ML techniques to evaluate their.suitability for.application in the hot defor.ation behavior.of metallic *** ML-based r.gr.ssion methods of Ar.ificial Neur.l Networ.s(ANNs),Suppor. Vector.Machine(SVM),Decision Tr.e r.gr.ssion(DTr.,and Gaussian Pr.cess r.gr.ssion(GPr.ar. applied to mathematically descr.be hot flow str.ss cur.e datasets acquir.d exper.mentally for.a medium-car.on *** the GPr.method has not been used for.such a r.gr.ssion task befor.,the r.sults showed that its per.or.ance is the most favor.ble and pr.ctically unr.valed;neither.the ANN method nor.the other.studied ML techniques pr.vide such pr.cise r.sults of the solved r.gr.ssion analysis.

关键词： Machine lear.ing Gaussian pr.cess r.gr.ssion ar.ificial neur.l networ.s suppor. vector.machine hot defor.ation behavior

Heter.geneity of matur. oligodendr.cytes in the centr.l ner.ous system

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Neur.l r.gener.tion r.sear.h 2025年第5期20卷 1336-1349页

作者： Chao Weng Adam M.r.Gr.h Moein Yaqubi Qiao-Ling Cui Jo Anne Str.tton G.r.Wayne Moor. Jack P.Antel Neur.immunology Unit Montreal Neurological Institute-HospitalDepartment of Neurology and NeurosurgeryMcGill UniversityMontrealQCCanada Depar.ment of Neur.logy Renmin Hospital of Wuhan UniversityWuhanHubei ProvinceChina

Matur. oligodendr.cytes for. myelin sheaths that ar. cr.cial for.the insulation of axons and efficient signal tr.nsmission in the centr.l ner.ous *** evidence has challenged the classical view of the functionally static matur. oligodendr.cyte and r.vealed a gamut of dynamic functions such as the ability to modulate neur.nal cir.uitr. and pr.vide metabolic suppor. to *** the r.cognition of potential heter.geneity in matur. oligodendr.cyte function,a compr.hensive summar. of matur. oligodendr.cyte diver.ity is *** delve into ear.y 20th-centur. studies by r.ber.son and r.o-Hor.ega that laid the foundation for.the moder. identification of r.gional and mor.hological heter.geneity in matur. ***,r.cent mor.hologic and functional studies call into question the long-assumed homogeneity of matur. oligodendr.cyte function thr.ugh the identification of distinct subtypes with var.ing myelination ***,moder. molecular.investigations,employing techniques such as single cell/nucleus r.A sequencing,consistently unveil at least six matur. oligodendr.cyte subpopulations in the human centr.l ner.ous system that ar. highly tr.nscr.ptomically diver.e and var. with centr.l ner.ous system *** and disease r.lated matur. oligodendr.cyte var.ation denotes the impact of pathological conditions such as multiple scler.sis,Alzheimer.s disease,and psychiatr.c ***,caution is war.anted when subclassifying matur. oligodendr.cytes because of the simplification needed to make conclusions about cell identity fr.m tempor.lly confined *** studies lever.ging advanced techniques like spatial tr.nscr.ptomics and single-cell pr.teomics pr.mise a mor. nuanced under.tanding of matur. oligodendr.cyte *** r.sear.h avenues that pr.cisely evaluate matur. oligodendr.cyte heter.geneity with car. to under.tand the mitigating influence of species,sex,centr.l ner.ous system r.gion,age,and disease,

关键词： aging centr.l ner.ous system diseases electr.n micr.scopy heter.geneity immunohistochemistr. myelin sheath natur.l histor. neur.glia oligodendr.glia single-cell gene expr.ssion analysis

Spastin and alsin pr.tein inter.ctome analyses begin to r.veal key canonical pathways and suggest novel dr.ggable tar.ets

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Neur.l r.gener.tion r.sear.h 2025年第3期20卷 725-739页

作者： Benjamin r.Helmold Angela Ahr.ns Zachar. Fitzger.ld P.Hande Ozdinler Depar.ment of Neur.logy Feinberg School of MedicineNorthwestern UniversityChicagoILUSA Center.for.Molecular.Innovation and Dr.g Discover. Center for Developmental TherapeuticsChemistry of Life Processes InstituteNorthwestern UniversityEvanstonILUSA Mesulam Center.for.Cognitive Neur.logy and Alzheimer.s Disease Feinberg School of MedicineNorthwestern UniversityChicagoILUSA Feinber. School of Medicine Les Turner ALS Center at Northwestern UniversityChicagoILUSA

Developing effective and long-ter. tr.atment str.tegies for.r.r. and complex neur.degener.tive diseases is challenging. One of the major.r.adblocks is the extensive heter.geneity among patients. This hinder. under.tanding the under.ying disease-causing mechanisms and building solutions that have implications for.a br.ad spectr.m of patients. One potential solution is to develop per.onalized medicine appr.aches based on str.tegies that tar.et the most pr.valent cellular.events that ar. per.ur.ed in patients. Especially in patients with a known genetic mutation, it may be possible to under.tand how these mutations contr.bute to pr.blems that lead to neur.degener.tion. Pr.tein–pr.tein inter.ction analyses offer.gr.at advantages for.r.vealing how pr.teins inter.ct, which cellular.events ar. pr.mar.ly involved in these inter.ctions, and how they become affected when key genes ar. mutated in patients. This line of investigation also suggests novel dr.ggable tar.ets for.patients with differ.nt mutations. Her., we focus on alsin and spastin, two pr.teins that ar. identified as “causative” for.amyotr.phic later.l scler.sis and her.ditar. spastic par.plegia, r.spectively, when mutated. Our.r.view analyzes the pr.tein inter.ctome for.alsin and spastin, the canonical pathways that ar. pr.mar.ly impor.ant for.each pr.tein domain, as well as compounds that ar. either.Food and Dr.g Administr.tion–appr.ved or.ar. in active clinical tr.als concer.ing the affected cellular.pathways. This line of r.sear.h begins to pave the way for.per.onalized medicine appr.aches that ar. desper.tely needed for.r.r. neur.degener.tive diseases that ar. complex and heter.geneous.

关键词： ALS2 alsin amyotr.phic later.l scler.sis her.ditar. spastic par.plegia neur.degener.tive diseases per.onalized medicine pr.cision medicine pr.tein inter.ctome pr.tein-pr.tein inter.ctions SPAST spastin