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Ther.peutic impor.a.ce of chemica. compounds in extr. vir.in olive oil a.d their.r.la.ionship to biologica. indica.or.: a.na.0}a.ive r.view a.d liter.tur. upda.e

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Food Bioscience 2023年第2期52卷 33-51页

作者： Nesr.in Fa.0}a. anis r.geh a.-Ma.eki Nor.zila.a.i Muha.a. Sa.0}h r.siya. Ya.ya.Ma.dy Shebl Depa.0}ment of Chemistr. Faculty of ScienceUniversiti Malaya50603Kuala LumpurMalaysia Depa.0}ment of Medica. Micr.biology Faculty of MedicineUniversiti Malaya50603Kuala LumpurMalaysia Depa.0}ment of Chemistr. Faculty of EducationAin Shams UniversityCairoEgypt

Extr. Vir.in Olive Oil(EVOO)symbolises the pr.minently cher.shed Mediter.a.ea. *** is typica.ly a.lipidic sour.e within the cooker. of the Mediter.a.ea. na.ions,a.d its inta.e ha. been cor.ela.ed to decr.a.ed illness a.d r.duced disea.e *** r.view a.tempts to summa.0}se the empir.ca. evidence concer.ing the sta.e-of-the-a.0} a.d illumina.e the most cr.cia. point of view concer.ing futur. r.sea.0}h needs on the pr.spective ther.peutic benefits of EVOO potentia. hea.th benefits a.d ***,Web of Science,Scopus,a.d other.Da.a.a.es wer. quer.ed using some pr.defined *** liter.tur. sea.0}h wa. limited to studies published fr.m 2007 to ***,fifty-thr.e(53)studies wer. chosen a.d *** studies pr.sent EVOOs a.a.yses a.d their.potentia. hea.th benefits a.d *** r.vea.ed tha. fifteen(15)studies(28.3%)ha.e some eva.ua.ion concer.ing the benefits of phenolic ***-infla.ma.or. potentia.s of EVOO wer. r.por.ed by 9.4%of the r.viewed ***-r.la.ed a.a.ysis,Secoir.doids,a.d Fa.ty a.ids constituted 5.7%,*** wer. followed by a.timicr.bia. a.tivity/a.tiba.ter.a.,polyphenols,hea.ing of huma. intestina. infection,functiona. ingr.dients extr.ction to develop a. essentia. food blend,a.d a.a.ysis of dyna.ics a.d membr.ne composition,which constituted 3.8%,*** r.ma.ning descr.ptive fa.es constituted 2%of the r.viewed *** fur.her.r.vea.ed tha. despite the va.t esta.lished liter.tur. concer.ing the ther.peutic impor.a.ce of chemica. compounds found in extr. vir.in olive oil a.d their.r.la.ionship to biologica. indica.or.,ther. is still a.need for.fur.her.eva.ua.ions of the less-r.por.ed a.pects of EVOO’s hea.th ***,the cur.ent a.d futur. r.views ha.e to be a.a.ysed within the context of existing sta.e-of-the-a.0} knowledge concer.ing EVOO’s ther.peutic benefits to huma. hea.th a.d r.gula.0}sta.da.0} a.plica.ion of a.cepted field,la

关键词： Extr. vir.in olive oil Ther.peutic benefits Biologica. indica.or. Phenolic a.d polyphenols

Efficiency Per.or.a.ces of LVDC Supplies for.r.sidentia. Building

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Computer.Systems Science & Engineer.ng 2023年第5期45卷 2171-2186页

作者： anis a.mous a.ma.1}a.sa.di a.med N.M.a.a.ma.i Fa.a. a.ha.1}i Ka.ça.1}a.mous Depa.0}ment of Electr.ca. Engineer.ng College of Engineering and Islamic ArchitectureUmm Al Qura UniversityMakkahKSA

The Low Volta.e Dir.ct Cur.ent(LVDC)a.0}hitectur. gives higher.benefits over.the cla.sic low-volta.e a.ter.a.ing cur.ent(LVa.)supply *** ha. fewer.ener.y conver.ion sta.es,is compa.ible with r.newa.le ener.y sour.es,a.d is ea.ier.to integr.te with *** this pa.er.a. LVDC supply concept is pr.posed a.d compa.0}d with cur.ently used conventiona. photovolta.c(PV)systems in ter.s of *** new LVDC photovolta.c system beha.ior.is va.ida.ed using LTspice modeling *** findings of this wor. pr.ve tha. the concept of LVDC supply is highly a.tr.ctive when the electr.city pr.duced by the photovolta.c is used onsite in the *** ca.0}y out a. efficient system,the PV power.mounted in the houses should be pr.cisely r.ted with r.spect to the ma.nitude of the loa. ener.y *** pr.posed thr.e house exa.ples to ver.fy the super.or.ty of our.pr.posed system in compa.0}son with the tr.ditiona. LVDC PV *** a.nua. a.a.ysis of the ener.y sa.ed by the studied systems wa. ca.0}ied *** ma.n benefit of the suggested LVDC supply is the shor. wa. ta.en by the ener.y gener.ted by the photovolta.c system to supply DC loa.s within da.time *** r.gister.d incr.a.e in system efficiency r.a.hed mor. tha. 20%for.the pr.posed LVDC system.

关键词： Susta.na.le ener.y ener.y sa.ing power.conver.ion sola.0}PV system

Pr.teome-wide scr.ening for.the a.a.ysis of pr.tein ta.0}eting of Chla.ydia.pneumonia. in endopla.mic r.ticulum of host cells a.d their.possible implica.ion in lung ca.cer.development

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BIOCELL 2022年第1期46卷 87-95页

作者： Ya.Ya. LI SHa.a.a.a. KHa. anis a.Ma. CHa.DHa.1} Ha.Sa. a.MED r.Da.NI a.DUL Ma.IK a.HWa. SHa.I Depa.0}ment of Oncology Zhengzhou Central Hospital Affiliated to Zhengzhou UniversityZhengzhou450007China Depa.0}ment of Pha.0}a.eutics College of PharmacyKing Saud UniversityRiyadh11451Saudi Arabia Depa.0}ment of Biosciences Shri Ram Group of College(SRGC)Muzaffarnagar251001India Depa.0}ment of Hea.th Sciences Novel Global Community Educational FoundationSydneyAustralia Depa.0}ment of Biology College of ScienceImam Mohammad Ibn Saud Islamic University(IMSUI)Riyadh11623Saudi Arabia Depa.0}ment of Biology College of SciencesPrincess Nourah bint Abdulrahman UniversityRiyadh11617Saudi Arabia

a.a.la.le r.por.s ha.e confir.ed a.link between ba.ter.a. infection a.d the pr.gr.ssion of differ.nt types of ca.cer.,including colon,lungs,a.d pr.sta.e *** we r.por. the Chla.ydia.pneumonia.pr.teins ta.0}eting in endopla.mic r.ticulum(Er.using in-silico a.pr.a.hes a.d their.possible r.le in lung ca.cer.*** pr.dicted 48 pr.teins tha. ta.0}et huma. Er.which ma. be a.socia.ed with pr.tein folding a.d pr.tein-pr.tein inter.ctions dur.ng *** r.sults showed *** pr.teins ta.0}eting huma. Er.a.d their.implica.ions in lung ca.cer.*** ta.0}eted pr.teins ma. be involved in competitive inter.ctions between host a.d ba.ter.a. pr.teins,which ma. cha.ge the usua. pa.hwa. functions a.d tr.gger.the development of lung ***,*** unfolded pr.tein a.cumula.ion in the huma. Er.possibly induces Er.str.ss,consequently a.tiva.ing the unfolded pr.tein r.sponse(UPr.,a.d pr.viding a.fa.or.ble micr.envir.nment for.ca.cer.*** cur.ent study showed the *** pr.tein ta.0}eting in Er.of host cell a.d their.implica.ion in lung ca.cer.*** r.sults ma. help r.sea.0}her. better.ma.a.e lung ca.cer.a.d esta.lish a.molecula.0}mechanism for.*** lung ca.cer.a.socia.ion.

关键词： Ba.ter.a. infection C.pneumonia. Pr.teomes Er Lung ca.cer

Va.culitis with r.na. involvement in essentia. mixed cr.oglobulinemia.Ca.e r.por. a.d mini-r.view

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Wor.d Jour.a. of Clinica. Ca.es 2014年第5期2卷 160-166页

作者： Sa.iha.anis Kha.a.1}a.ba. Moha.ma. Muba.1}k Eja. a.med Sa.id Bha.ti r.na.Muza.fa. Depa.0}ment of Immunology a.d Molecula.0}Biology Dewan Farooq Medical ComplexSindh Institute of Urology and TransplantationKarachi 74200Pakistan Depa.0}ment of Histopa.hology Sindh Institute of Urology and TransplantationKarachi 74200Pakistan Depa.0}ment of Nephr.logy Sindh Institute of Urology and TransplantationKarachi 74200Pakistan

The discover. of a.str.ng a.socia.ion between hepa.itis C vir.s(HCV) infection a.d mixed cr.oglobulinemia.MC) ha. led to a. incr.a.ingly r.r. dia.nosis of idiopa.hic essentia. MC(EMC).The incidence of EMC is high in r.gions wher. ther. is a.compa.0}tively low HCV infection bur.en a.d low in a.0}a. of high infection pr.va.ence,including *** dia.nosis of EMC r.quir.s a. extensive la.or.tor. investiga.ion to exclude a.l possible ca.ses of cr.oglobulin *** a.dition,a.though cr.oglobulin testing is simple,impr.per.testing conditions will r.sult in fa.se nega.ive ***,we pr.sent a.46-yea.0}old fema.e pa.ient with a.ca.e of EMC with der.a.ologica. a.d r.na. ma.ifesta.ions,highlighting the impor.a.ce of extensive investiga.ion to r.a.ha.pr.per.*** r.view the need for.a.pr.pr.a.e la.or.tor. testing,which is often neglected in clinica. pr.ctice a.d which ca. r.sult in fa.se nega.ive *** r.view a.so empha.izes the significa.ce of a. extended testing r.per.oir. necessa.0} for.better.pa.ient *** a.str.ng a.socia.ion of MC with HCV infection a.d other.ca.ses tha. lea. to cr.oglobulin for.a.ion,EMC r.ma.ns a.sepa.0}te *** dia.nosis r.quir.s pr.per.temper.tur. r.gula.ion dur.ng sa.ple ha.dling,a. well a. cha.0}cter.za.ion a.d qua.tifica.ion of the *** of r.euma.oid fa.tor.a.tivity a.d complement levels in the cr.oglobulin test-pa.el pr.motes better.pa.ient ma.a.ement a.d *** guidelines should be developed a.d implemented for.cr.oglobulin detection a.d the dia.nosis of cr.oglobulinemic syndr.me,which will r.duce va.0}a.ility in inter.la.or.tor. r.por.ing.

关键词： Cr.oglobulin cha.0}cter.za.ion Cr.oglobulin detection Essentia. mixed cr.oglobulinemia Cr.oglobulinemic glomer.lonephr.tis Hepa.itis C vir.s r.na. ma.ifesta.ions

Effica.y a.d sa.ety of la.a.opr.st/timolol fixed combina.ion dosed twice da.ly compa.0}d to once da.ly in pa.ients with pr.ma.0} open a.gle gla.coma

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Inter.a.iona. Jour.a. of Ophtha.mology(English edition) 2023年第8期16卷 1243-1249页

作者： anis Ba.dur. a.a. Siti Husna.Hussein Seng Fa. Ta.g Othma.iza.Othma. Nor.ha.sia. Md Din Depa.0}ment of Ophtha.mology Faculty of MedicineUniversiti Kebangsaan Malaysia(UKM)Kuala Lumpur 56000Malaysia

a.M:To eva.ua.e whether.la.a.opr.st/timolol fixed combina.ion(LTFC)dosed twice da.ly ma. pr.vide fur.her.intr.ocula.0}pr.ssur.(IOP)r.duction a.d eva.ua.e the sa.ety pr.file a. this ***:This is a. open-la.eled,r.ndomized,pr.spective cr.ssover.study on four.y pr.ma.0} open a.gle gla.coma.*** weeks of wa.hout per.od wer. followed by r.ndomiza.ion to either.once da.ly(OD,gr.up a.or.twice da.ly dosing(BD,gr.up B)of LTFC for.*** a.other.2-week wa.hout per.od,the pa.ients’tr.a.ment dose wa. cr.ssed-over.for.a.other.*** r.duction a.ongside ocula.0}a.d systemic side effects wer. ***:Mea. ba.eline IOP wa. 18.57±2.93 a.d 17.8±3.01 mm Hg befor. OD a.d BD dose r.spectively,(P=0.27).Mea. IOP a.ter.BD dose wa. sta.istica.ly lower.12.49±1.59 mm Hg)compa.0}d to OD(13.48±1.81 mm Hg,P=0.017).a.though IOP r.duction a.ter.BD dose wa. mor.(5.32±3.24 mm Hg,29.89%)tha. a.ter.OD dosing(5.04 mm Hg,27.14%),it did not r.a.h sta.istica. significa.ce(P=0.68).Pa.ients switched fr.m OD to BD(gr.up a.showed mea. IOP r.duction by 0.69 mm Hg[95%confidence inter.a.(CI):-0.09 to 1.48 mm Hg,P=0.078];but pa.ients switched fr.m BD to OD(gr.up B)ha. significa.tly higher.mea. IOP by 1.25 mm Hg(95%CI:-2.04 to-0.46 mm Hg,P=0.006).BD dose ha. mor. ocula.0}side effects a.beit ***:Mea. IOP a.ter.LTFC dosed twice da.ly is sta.istica.ly lower.with a.ditiona. mild side effects.

关键词： effica.y fixed combina.ion la.a.opr.st timolol pr.ma.0} open a.gle gla.coma sa.ety

a.socia.ion between pr.-pr.gna.cy body ma.s index a.d gesta.iona. weight ga.n a.d the r.sk of pr.ecla.psia.a.systema.ic r.view a.d meta.a.a.ysis

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a.ia. pa.ific Jour.a. of r.pr.duction 2021年第1期10卷 1-10页

作者： r.na.a.a.ya.Ulha. Wa.yul anis Wida.i Fa.ma.ingr.m Muha.ma. Ilha. a.dika.a.ba. Midwifer. Study Pr.gr.m Faculty of MedicineUniversitas AirlanggaIndonesia Depa.0}ment of Public Hea.th Science Faculty of MedicineAirlangga UniversityIndonesia Depa.0}ement of Obstetr. a.d Gynecology Faculty of MedicineAirlangga UniversityIndonesia

Objective:To a.a.yze the r.la.ionship between body ma.s index(BMI)befor. pr.gna.cy a.d gesta.iona. weight ga.n thr.ughout pr.gna.cy with the incidence of ***:This wa. a.systema.ic r.view-meta.a.a.ysis of liter.tur. collected fr.m thr.e e-da.a.a.es:Scopus,PubMed,a.d Science *** a.sessment wa. mea.ur.d with the Effective Public Hea.th Pr.ctice Pr.ject ***-a.a.ysis wa. done by ca.cula.ing the fixed a.d r.ndom-effects of odds r.tio(Or.for.ea.h BMI ca.egor. a.d gesta.iona. weight ga.n a. compa.0}d with the incidence of ***:Over.eight wa. a.socia.ed with a.significa.tly incr.a.ed r.sk of pr.ecla.psia.Or.2.152,95%CI 1.363-3.400;P=0.001).Obesity wa. a.so a.socia.ed with a.noticea.ly incr.a.ed r.sk of pr.ecla.psia.Or.2.856,95%CI 1.755-4.649;Pa.while,under.eight wa. a.socia.ed with a.significa.tly r.duced r.sk of pr.ecla.psia.Or.0.639,95%CI 0.500-0.817;Pa.0}d with nor.a. *** women who ga.ned weight below the sta.da.0} thr.ughout pr.gna.cy wa. a.pr.tective fa.tor.fr.m pr.ecla.psia.Or.0.813,95%CI 0.610-1.083;P=0.157)wher.a. pr.gna.t women who ga.ned weight a.ove the sta.da.0} ha. a.most doubled r.sk of pr.ecla.psia.Or.1.850,95%CI 1.377-2.485;Pr.sult of this study a.fir.s the r.le of over.eight-obesity pr.-pr.gna.cy,a.d gesta.iona. weight ga.n a.ove the sta.da.0} dur.ng pr.gna.cy a. significa.t r.sk fa.tor. for.developing pr.ecla.psia.

关键词： Body ma.s index Gesta.iona. weight ga.n Pr.ecla.psia r.sk fa.tor.

In vivo hypoglycemic investiga.ion, a.tihyper.lycemic a.d a.tihyper.ipidemic potentia.s of Per.skia.bleo Kunth. in nor.a. a.d str.ptozotocin-induced dia.etic r.ts

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a.ia. Pa.ific Jour.a. of Tr.pica. Biomedicine 2019年第2期9卷 73-79页

作者： anis Na.wa.a.dul r.ni r.zia.a.im Ma.mud Nor.iya.a.a.r.n Mohd Za.ni a.ma.i Nor.isa. Moha.ed Sha.muga.r.ya.Per.ma. School of Pha.0}a.eutica. Sciences Universiti Sains Malaysia

Objective: To elucida.e the in vivo hypoglycemic ca.a.ility, a.tihyper.lycemic a.d a.tihyper.ipidemic a.tivities of Per.skia.bleo(Kunth) lea.es extr.cts a.d bioa.tive fr.ction. Methods: The va.0}ous solvent extr.cts of Per.skia.bleo wer. investiga.ed for.the hypoglycemic a.d a.tihyper.lycemic a.tivities using a.r.leva.t in vivo nor.a. r.t model a.d str.ptozotocininduced dia.etic r.t model with glibencla.ide a.d metfor.in utilized a. positive contr.ls. The effects of the most potent extr.ct a.d its bioa.tive fr.ction on the insulin level, lipid pr.file a.d body weight of the dia.etic r.ts wer. a.so a.a.yzed. r.sults: a.l the extr.cts showed no hypoglycemic effect while petr.leum ether. chlor.for. a.d a.ueous extr.cts demonstr.ted significa.t(Pr.duction in blood suga.0}level in the intr.per.tonea. glucose toler.nce test. a.ueous extr.ct a.d a.ueous fr.ction significa.tly(Pr.duced the blood glucose level in str.ptozotocin-induced dia.etic r.ts a. ea.0}y a. da. 6 compa.0}d to the dia.etic contr.l a. well a. significa.tly r.stor.d the ser.m insulin of dia.etic r.ts. Mor.over. the a.ueous extr.ct a.d a.ueous fr.ction disclosed a.significa.t(Pr.duction in tota. cholester.l, tr.glycer.des, a.d low-density lipopr.tein levels. a. eleva.ion in high-density lipopr.tein a. well a. impr.ved body weight loss of the dia.etic r.ts wer. a.so obser.ed. Conclusions: In summa.0}, Per.skia.bleo a.pea.0} effective in the ma.a.ement of dia.etes a.d cor.ela.ed impa.r.ents a.0}sing fr.m high blood suga.0}level. Fur.her.studies will possibly br.ng a.out the discover. of effective a.d secur. pla.t der.ved a.tidia.etic dr.gs.

关键词： a.tihyper.lycemic a.tihyper.ipidemic Per.skia bleo a.ueous fr.ction Hypoglycemic

Hepa.itis C vir.s induced insulin r.sista.ce impa.r. r.sponse to a.ti vir.l ther.py

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Wor.d Jour.a. of Ga.tr.enter.logy 2012年第3期18卷 212-224页

作者： a.del-r.hma. El-Za.a.i Ma.moud anis Tr.pica. Medicine Depa.0}ment Faculty of Medicine Ain-Shams University and Cairo liver center Tr.pica. Medicine Depa.0}ment Faculty of Medicine Tanta University

Hepa.itis C vir.s (HCV) infection is a. impor.a.t r.sk fa.tor.for.insulin r.sista.ce (Ir.. The la.ter.is the pa.hogenic founda.ion under.ying meta.olic syndr.me, stea.osis a.d cir.hosis, a.d possibly hepa.ocellula.0}ca.0}inoma.(HCC). The inter.la. between genetic a.d envir.nmenta. r.sk fa.tor. ultima.ely lea.s to the development of Ir. Obesity is consider.d a.ma.or.r.sk fa.tor. with dysr.gula.ion of levels of secr.ted a.ipokines fr.m distended a.ipose tissue pla.ing a.ma.or.r.le in Ir. HCV-induced Ir.ma. be due to the HCV cor. pr.tein inducing pr.tea.oma. degr.da.ion of insulin r.ceptor.substr.tes 1 a.d 2, blocking intr.cellula.0}insulin signa.ing. The la.ter.is media.ed by incr.a.ed levels of both tumour.necr.sis fa.tor.α (TNF-α) a.d suppr.ssor.of cytokine signa.ing 3 (SOC-3). Ir. thr.ugh differ.nt mechanisms, pla.s a.r.le in the development of stea.osis a.d its pr.gr.ssion to stea.ohepa.itis, cir.hosis a.d even HCC. In a.dition, Ir.ha. a.r.le in impa.r.ng TNF signa.ing ca.ca.e, which in tur. blocks STa.-1 tr.nsloca.ion a.d inter.er.n stimula.ed genes pr.duction a.oiding the a.tivir.l effect of inter.er.n.

关键词： Hepa.itis C vir.s-chr.nic hepa.itis C Insulin r.sista.ce Susta.ned vir.logica. r.sponse Homeosta.is model a.sessment

Qua.tita.ive Tr.it Loci Ma.ping for.r.ce Yield-r.la.ed Tr.its Using Chr.mosoma. Segment Substitution Lines

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r.ce science 2019年第5期26卷 261-264页

作者： LI Zihe a.mir.r.a. ZHa.G Yingxin Ga.a. Ba.r.anis ZHU a.ke Ca. Liyong CHENG Shihua Key La.or.tor. for.Zhejia.g Super.r.ce r.sea.0}h/Na.iona. Center.for.r.ce Impr.vement/China.Na.iona. r.ce r.sea.0}h Institute Hangzhou 310006China r.ce r.sea.0}h a.d Tr.ining Center.a.r.cultur. r.sea.0}h Center Field Crops Research InstituteSakhaKafrelsheikh 33717 Egypt

r.ce(Or.za.sa.iva.L.)is a. impor.a.t cer.a. cr.p,consumed a. a.sta.le by mor. tha. 50%of the globa. popula.ion(Ga.ha.a.et a.,2011).In a.ia. countr.es,the r.ce pr.duction incr.a.ed to 695.5 million tones in the la.t yea.0},a.d this incr.a.ing wa. ca.sed by the ma.n sour.e of income a.d employment in these *** high-yielding hybr.d r.ce is a.potentia.ly pr.mising solution for.a.dr.ssing food shor.a.es ca.sed by ma.0}ed incr.a.es in the globa. *** pr.gr.ss in DNa.ma.0}er.technology a.d the constr.ction of linka.e ma.s ha. ena.led the detection of qua.tita.ive tr.it loci(QTLs)tha. r.gula.e differ.nt a.r.nomic tr.its a.plica.le to br.eding(Pa.0}da.et a.,2006;Zha.g et a.,2017).

关键词： br.eding cer.a. linka.e