检索结果-南通市图书馆

structural effects induced by dialysis-based purification of carbon nanomaterials

Nano Materials science 2024年第4期6卷 475-483页

作者： A.D.Veloso A.M.Ferraria A.M.Botelho do rego A.s.Viana A.J.s.Fernandes A.J.Fielding r.A.Videira M.C.Oliveira CQ-Vr and Chemistry Department University of Trás-os-Montes e Alto Douro BsIrG iBB-Institute for Bioengineering and BiosciencesDepartment of Chemical Engineeringand Associate Laboratory i4HB-Institute for Health and BioeconomyInstituto Superior TécnicoUniversidade de Lisboa Centro de Química Estrutural Institute of Molecular SciencesDepartamento de Química e BioquímicaFaculdade de CiênciasUniversidade de Lisboa I3N and Physics Department University of AveiroCampus de Santiago Faculty of science Pharmacy and Biomolecular SchoolLiverpool John Moores University rEQUIMTE/LAQV Laborat orio de FarmacognosiaDepartamento de QuímicaFaculdade de Farm aciaUniversidade do Porto

Dialysis plays a crucial role in the purification of nanomaterials but its impact on the structural properties of carbon nanomaterials was never ***,a carbon-based nanomaterial generated electrochemically in potassium phosphate buffer,was characterized before and after dialysis against pure *** is shown that dialysis affects the size of the carbon domains,structural organization,surface functionalization,oxidation degree of carbon,and grade of ***,dialysis drives the nanomaterial organization from discrete roundish carbon domains,with sizes ranging from 70 to 160 nm,towards linear stacking structures of small nanoparticles （rallel,alcohol and ether （epoxide） surface groups evolve into more oxidized carbon groups （e.g.,ketone and ester groups）.Investigation of the as-prepared nanomaterial by electron paramagnetic resonance （EPr） revealed a resonance signal consistent with carbon-oxygen centred ***,this study brings to light the selective affinity of the carbon nanomaterial under study to capture Na+ions,a property greatly enhanced by the dialysis process,and its high ability to trap oxygen,particularly before *** findings open new perspectives for the application of carbon-based nanomaterials and raise awareness of the importance of structural changes that can occur during the purification of carbon-based nanomaterials.

关键词： Nanocarbon surface functionalization NMr XPs Hydrophilic carbon Paramagnetic

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Multidimensional images and aberrations in sTEM

引用

Chinese Physics B 2024年第9期33卷 68-74页

作者： Eric r.Hoglund Andrew r.Lupini Center for Nanophase Materials sciences Oak Ridge National LaboratoryOak RidgeTN 37831United States

recent advances in scanning transmission electron microscopy(sTEM)have led to increased development of multidimensional sTEM imaging modalities and novel image reconstruction *** interest arises because the main electron lens in a modern transmission electron microscope usually has a diffraction-space information limit that is significantly better than the real-space resolution of the same *** state-of-affairs is sometimes shared by other scattering methods in modern physics and contributes to a broader excitement surrounding multidimensional techniques that scan a probe while recording diffraction-space images,such as ptychography and scanning nano-beam ***,the contrasting resolution in the two spaces raises the question as to what is limiting their effective ***,we examine this paradox by considering the effects of aberrations in both image and diffraction planes,and likewise separate the contributions of pre-and post-sample *** consideration provides insight into aberration-measurement techniques and might also indicate improvements for super-resolution techniques.

关键词： scanning transmission electron microscopy (sTEM) aberrations

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

The autophagy protein Atg9 functions in glia and contributes to parkinsonian symptoms in a Drosophila model of Parkinson’s disease

引用

Neural regeneration research 2024年第5期19卷 1150-1155页

作者： shuanglong Yi Linfang Wang Margaret s.Ho shiping Zhang school of Life science and Technology ShanghaiTech UniversityShanghaiChina College of Life sciences University of Chinese Academy of SciencesBeijingChina

Parkinson’s disease is a progressive neurodegenerative disease characterized by motor deficits,dopaminergic neuron loss,and brain accumulation ofα-synuclein aggregates called Lewy *** in protein degradation pathways,such as autophagy,has been demonstrated in neurons as a critical mechanism for eliminating protein aggregates in Parkinson’s ***,it is less well understood how protein aggregates are eliminated in glia,the other cell type in the *** the present study,we show that autophagy-related gene 9(Atg9),the only transmembrane protein in the autophagy machinery,is highly expressed in Drosophila glia from adult *** from immunostaining and live cell imaging analysis reveal that a portion of Atg9 localizes to the trans-Golgi network,autophagosomes,and lysosomes in ***9 is persistently in contact with these *** glial atg9 reduces the number of omegasomes and autophagosomes,and impairs autophagic substrate *** suggests that glial Atg9 participates in the early steps of autophagy,and hence the control of autophagic ***,loss of glial atg9 induces parkinsonian symptoms in Drosophila including progressive loss of dopaminergic neurons,locomotion deficits,and glial *** findings identify a functional role of Atg9 in glial autophagy and establish a potential link between glial autophagy and Parkinson’s *** results may provide new insights on the underlying mechanism of Parkinson’s disease.

关键词： Atg9 autophagy glia Parkinson’s disease

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Characterization of early maturing elite genotypes based on MTsI and MGIDI indexes:an illustration in upland cotton(Gossypium hirsutum L.)

引用

Journal of Cotton research 2024年第3期7卷 253-265页

作者： D s rAJ supritha PATIL rajesh s. PATIL Bhuvaneshwara r. NAYAK spurthi N. PAWAr Kasu N. Department of Genetics and Plant Breeding College of AgricultureUniversity of Agricultural SciencesDharwad 580005India Agricultural research station Dharwad 580005India Department of Biotechnology College of AgricultureUniversity of Agricultural SciencesDharwad 580005India Department of Crop Physiology College of AgricultureUniversity of Agricultural SciencesDharwad 580005India

Background Globally,the cultivation of cotton is constrained by its tendency for extended periods of *** maturity plays a potential role in rainfed-based multiple cropping system especially in the current era of climate *** the current study,a set of 20 diverse Gossypium hirsutum genotypes were evaluated in two crop seasons with three planting densities and assessed for 11 morphological traits related to early *** study aimed to identify genotype(s)that mature rapidly and accomplish well under diverse environmental conditions based on the two robust multivariate techniques called multi-trait stability index(MTsI)and multi-trait genotype-ideotype distance index(MGIDI).results MTsI analysis revealed that out of the 20 genotypes,three genotypes,viz.,NNDC-30,A-2,and s-32 accomplished well in terms of early maturity traits in two ***,three genotypes were selected using MGIDI method for each planting densities with a selection intensity of 15%.The strengths and weaknesses of the genotypes selected based on MGIDI method highlighted that the breeders could focus on developing early-maturing genotypes with specific traits such as days to first flower and boll *** selected genotypes exhibited positive genetic gains for traits related to earliness and a successful harvest during the first and second ***,there were negative gains for traits related to flowering and boll *** The study identified three genotypes exhibiting early maturity and accomplished well under different planting *** multivariate methods(MTsI and MGIDI)serve as novel approaches for selecting desired genotypes in plant breeding programs,especially across various growing *** methods offer exclusive benefits and can easily construe and minimize multicollinearity issues.

关键词： Cotton MTsI MGIDI Genotype environment interaction Early maturity Multi-trait Multi-environment

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Prevalence and Characterization of Pathogens responsible for Enteric Fever and Assessment of Their Antibiotic susceptibility Pattern in Bangladesh

引用

Pharmacology & Pharmacy 2024年第9期15卷 303-313页

作者： saima Mollick Md. Jabir Hasnain Md. saiful islam Tumpa Dasgupta Pharmaceutical sciences research Division BCSIR Laboratories Dhaka Bangladesh Council of Scientific and Industrial Research (BCSIR) Dhaka Bangladesh Directorate General of Drug Administration Dhaka Bangladesh Department of Clinical Pharmacy and Pharmacology Faculty of Pharmacy University of Dhaka Dhaka Bangladesh

In Bangladesh, Enteric fever is a persistent health issue throughout the year, occasionally reaching epidemic levels. The growing antibiotic resistance makes treatment increasingly challenging. Therefore, studying the antibiotic resistance patterns within the population is crucial to ensure a more effective treatment strategy. This study was designed to determine the prevalence, antimicrobial susceptibility profile, and factors associated with salmonella spp. infections among clinically suspected Enteric fever patients in Bangladesh. This study also aimed to investigate whether there has been a re-emergence in the susceptibility of bacterial strains to conventional drugs. Data were collected from February 2024 to July 2024, from patients suspected Enteric fever (fever less than seven days duration) in a Private Diagnostic Center of Bangladesh. A total of 195 blood samples were cultured, where 53.85% came out positive, among which 79.05% salmonella typhi and 20.95% salmonella paratyphi A were found. Prevalence of Typhoid fever was observed high among the school-going age group (0 - 15 years) patients. Both these organisms were susceptible to ceftazidime, cefixime, ceftriaxone and cefepime but resistant to nalidixic acid, ciprofloxacin and levofloxacin. Nalidixic Acid is resistant to all s. paratyphi A and sensitive to few s. typhi. Ciprofloxacin and levofloxacin showed delayed response (36.14% and 22.72% sensitive to s. typhi and s. paratyphi A, respectively) and resistance (63.85% and 77.27% resistant to s. typhi and s. paratyphi A, respectively). In case of s. typhi, the resistance was found against ampicillin (32.53%), chloramphenicol (27.71%), cotrimoxazole (24.09%) and the resistance of s. paratyphi A found against ampicillin (4.54%), chloramphenicol (0%) and cotrimoxazole (0%). This study will provide clinicians with alternative drug options and facilitate the effective treatment of Enteric fever.

关键词： Typhoid salmonella Nalidixic Acid Ciprofloxacin Chloramphenicol Cotrimoxazole

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

The Ca^(2+)-sensing receptor and the pocketome:comparing nature's complexity with human intervention in receptor modulation

引用

signal Transduction and Targeted Therapy 2024年第8期9卷 3153-3154页

作者： Edda s.F.Matthees Carsten Hoffmann Institut fur Molekulare Zellbiologie CMB-Center for Molecular BiomedicineUniversitatsklinikum JenaHans-Knoll StraBe 2D-07745 JenaGermany Friedrich-schiller-Universitat Jena Hans-KnollStraBe2D-07745 JenaGermany

In a recent paper published in Nature,the relatively understudied Ca^(2+)-sensing,receptor(Casr)within the Gprotein-coupled receptor(GPCr)family C,gained attention due to pioneering research led by Georgios skiniotis ... 详细信息

关键词： stanford gained skin

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

AutoML: A systematic review on automated machine learning with neural architecture search

引用

Journal of Information and Intelligence 2024年第1期2卷 52-81页

作者： Imrus salehin Md.shamiul islam Pritom saha s.M.Noman Azra Tuni Md.Mehedi Hasan Md.Abu Baten Department of Computer Engineering Dongseo University47 Jurye-roSasang-guBusan 47011Republic of Korea Department of Computer science and Engineering Daffodil International UniversityDhaka 1216Bangladesh Department of Computer science and Engineering Bangladesh University of Business and TechnologyDhaka 1216Bangladesh Faculty of Computer science and Engineering Frankfurt University of Applied SciencesFrankfurt 60318Germany Department of Computer science and Engineering University of Asia PacificDhaka 1205Bangladesh Department of Computer science and Engineering Ahsanullah University of Science and TechnologyDhaka 1208Bangladesh Department of Computer science and Engineering Northern University BangladeshDhaka 1215Bangladesh

AutoML(Automated Machine Learning)is an emerging field that aims to automate the process of building machine learning *** emerged to increase productivity and efficiency by automating as much as possible the inefficient work that occurs while repeating this process whenever machine learning is *** particular,research has been conducted for a long time on technologies that can effectively develop high-quality models by minimizing the intervention of model developers in the process from data preprocessing to algorithm selection and *** this semantic review research,we summarize the data processing requirements for AutoML approaches and provide a detailed *** place greater emphasis on neural architecture search(NAs)as it currently represents a highly popular sub-topic within the field of *** methods use machine learning algorithms to search through a large space of possible architectures and find the one that performs best on a given *** provide a summary of the performance achieved by representative NAs algorithms on the CIFAr-10,CIFAr-100,ImageNet and wellknown benchmark ***,we delve into several noteworthy research directions in NAs methods including one/two-stage NAs,one-shot NAs and joint hyperparameter with architecture *** discussed how the search space size and complexity in NAs can vary depending on the specific problem being *** conclude,we examine several open problems(sOTA problems)within current AutoML methods that assure further investigation in future research.

关键词： AutoML Neural architecture search Advance machine learning search space Hyperparameter optimization

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

C19MC mirNA-520G induces sP100 antiviral gene transcription and inhibits melanin production in skin cutaneous melanoma

引用

Genes & Diseases 2024年第1期11卷 60-63页

作者： Goodwin G.Jinesh Marian T.smallin Nino Mtchedlidze Isha Godwin Marco Napoli Nicole Hackel Manali s.Phadke Avani A.Deshpande Xiaobo Li John H.Lockhart Jaden r.Baldwin suehelay Acevedo-Acevedo Yifeng Gao Michelle A.reiser Keiran s.M.smalley Elsa r.Flores Andrew s.Brohl Department of Molecular Oncology H.Lee Moffitt Cancer Center&Research InstituteTampaFL 33612USA Molecular Medicine Program H.Lee Moffitt Cancer Center&Research InstituteTampaFL 33612USA saveetha Medical College ChennaiTamil Nadu 602105India Tumor Biology Department H.Lee Moffitt Cancer Center&Research InstituteTampaFL 33612USA sarcoma Department H.Lee Moffitt Cancer Center&Research InstituteTampaFL 33612USA

sP100 is an antiviral protein that restricts the productive stage of human papillomavirus(HPV)and multiple other viruses,and viruses in turn block sUMO-1-mediated stabilization of sP100 and promotes its degradation(Table s1).Interferon(IFN)signaling could still produce more sP100 through transcription to counteract viruses.1 Viruses also disable the transcriptional up-regulation of sP100 to achieve persistent infection in hosts.

关键词： sP100 melanoma stabilization

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Effect of proton irradiation on the optical properties of thermal control coating based on polystyrene with silica filler

引用

Propulsion and Power research 2024年第1期13卷 1-11页

作者： N.I.Cherkashina V.I.Pavlenko M.M.Mikhailov A.N.Lapin s.A.Yuriev r.V.sidelnikov D.s.romanyuk Belgorod state Technological University named after V.G.shoukhov Kostyukov Str.46Belgorod 308012Russia Tomsk state University of Control systems and radioelectronics 40Prospect LeninaTomsk 634050Russia

This paper presents the results of studying the surface properties changes of a ther-moregulating coating based on polystyrene and silicaﬁller after proton irradiation with an en-ergy of 50 keV at afluence of 3�1015 cm�*** proton irradiation,the values of the contact angle of wetting with water increase by 3.5%and 14.9%for polystyrene and the coating,*** free surface energy(energy of the surface layer)of polystyrene and the coat-ings before and after proton irradiation was calculated using the Owens-Wendt-rabel-Kaelble *** was a signiﬁcant increase in the polarity of the polystyrene surface(gp increased by a factor of 2.2)after proton *** the coating,an increase in gp by a factor of 3.89 was observed after proton *** changes in the coating were presented by Ir Fourier spectroscopy.A slight decrease in the absorption intensity of all characteristic bands compared to the unirradiated sample was *** was found that the irradiation of the coating with protons led to the formation of macromolecules with hydroxyl,carbonyl,and carboxyl bonds,as well as the formation of dimeric and oligomeric siloxane *** was also found that after irradiation of a pure polystyrene sample with protons,the value of the solar absorption as increased by only 4.2%;whereas for the coating with silicaﬁller,the value of as increased by 28.6%.

关键词： Thermal control coating Proton irradiation Hydrophobicity Free surface energy radiation crosslinking

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

sleep-based neuronal oscillations as a physiological biomarker for Alzheimer's disease:is night time the right time?

引用

Neural regeneration research 2024年第7期19卷 1417-1418页

作者： Jonathan Witton Erica s.Brady Michael T.Craig Department of Clinical and Biomedical sciences Faculty of Health and Life SciencesUniversity of ExeterExeterEnglandUK Gladstone Institute for Neurological Disease San FranciscoCAUSA school of Psychology and Neuroscience College of MedicalVeterinary and Life SciencesUniversity of GlasgowGlasgowScotlandUK

Dementia is a devastating syndrome characterized by memory problems,confusion,and behavior changes that prevent people from performing everyday *** is the leading cause of dependency and disability amongst older people,resulting in a global economic cost of ~$1.3 *** 58 million people are currently afflicted by dementia worldwide,with Alzheimer s disease(AD) causing most(60-70%) of these cases.

关键词： Alzheimer everyday performing

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：