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Percutaneous embolization by direct puncture for the treatment of high-flow priapism

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Asian Journal of Urology 2023年第2期10卷 208-209页

作者： quentin Holay Michael Baboudjian Eric Lechevallier Marc Andre Pierre-Henri Savoie Department of Radiology Conception Academic HospitalMarseilleFrance Department of Urology Conception Academic HospitalMarseilleFrance Department of Urology Sainte Anne HospitalToulonFrance

Dear Editor,High-flow priapism is a persistent erection,usually caused by blunt perineal trauma,resulting in pathologically increased arterial inflow to the corpora cavernosa[1].The therapeutic strategy of high-flow priapism,although codified,leaves room for a wide choice of techniques,ranging from conservative management,selective arterial embolization to surgical management[2].The aim of this letter was to report an alternative approach of percutaneous embolization by direct puncture for the treatment of high-flow priapism.

关键词： embolization puncture arterial

Actual and Potential InfiniteⅡ:A Newly Revealed Paradox

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西安翻译学院学报 2014年第2期21卷 67-73页

作者：林益 Bangyan Wen quentin Panger Department of Mathematics Pennsylvania State System of Higher Education at Slippery RockSlippery RockPA 16057USA Innovation Center for Economics and Logic Tianjin University of CommerceTianjinPR China Alana Drive SaxonburgPA 16056

DeregulationBenefits and Disadvantages

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DeregulationBenefits and Disadvantages

STAT5 promotes PD-L1 expression by facilitating histone lactylation to drive immunosuppression in acute myeloid leukemia

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作者： quentin J.Kilian egional Manager Regulatory Affairs Asia Pacific

＜正＞ The Need For A Good Regulatory EnvironmentAn open and transparent system is vital for *** of procedures Open Market Access Level Playing Field

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Signal Transduction and Targeted Therapy 2023年第10期8卷 5106-5118页

作者： Ze-Wei Huang Xue-Ning Zhang Ling Zhang Ling-Ling Liu Jing-Wen Zhang Yu-Xiang Sun Jue-Qiong Xu quentin Liu Zi-Jie Long Department of Hematology The Third Affiliated HospitalSun Yat-sen UniversityInstitute of HematologySun Yat-sen UniversityGuangzhouChina Department of Nephrology The Third Affiliated Hospitalun Yat-sen UniversityGuangzhouChina Sun Yat-sen University Cancer Center State Key Laboratory of Oncology in South ChinaSun Yat-sen UniversityGuangzhouChina

Immunotherapy is a revolutionized therapeutic strategy for tumor treatment attributing to the rapid development of genomics and immunology,and immune checkpoint inhibitors have successfully achieved responses in numbers of tumor types,including hematopoietic ***,acute myeloid leukemia(AML)is a heterogeneous disease and there is stll a lack of systematic demonstration to apply immunotherapy in AML based on PD-1/PD-L1 blockage.

关键词： myeloid acute leukemia

Latest development of double perovskite electrode materials for solid oxide fuel cells:a review

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Frontiers in Energy 2019年第4期13卷 770-797页

作者： Shammya AFROZE AfizulHakem KARIM quentin CHEOK Sten ERIKSSON Abul K.AZAD Faculty of Integrated Technologies Universiti Brunei DarussalamJalan Tunku LinkGadong BE 1410Brunei Darussalam Department of Chemistry and Chemical Enineering Energy and MaterialsEnvironmental Inorganic ChemistryChalmers University of TechnologyGoteborg SE 41296Sweden

Recently,the development and fabrication of electrode component of the solid oxide fuel cell(SOFC)have gained a significant importance,especially after the advent of electrode supported *** function of the electrode involves the facilitation of fuel gas diffusion,oxidation of the fuel,transport of electrons,and transport of the byproduct of the electrochemical *** progress has been made in the development of alternative electrode materials with mixed conducting properties and a few of the other composite *** the operation of a SOFC,it is necessary to avoid carburization and sulfidation *** present review focuses on the various aspects pertaining to a potential electrode material,the double perovskite,as an anode and cathode in the *** than 150 SOFCs electrode compositions which had been investigated in the literature have been *** evaluation has been performed in terms of phase,structure,diffraction pattern,electrical conductivity,and power *** methods adopted to determine the quality of electrode component have been provided in *** review comprises the literature values to suggest possible direction for future research.

关键词： double perovskites electrode materials hydrocarbon fuel solid oxide fuel cells

法国和中国之间的食品和饮料业务：进化的障碍

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法国和中国之间的食品和饮料业务：进化的障碍

作者： DUMAS quentin 上海外国语大学

学位级别：硕士

本论文旨在通过对目前公司使用的低效趋势和方法的分析和批评,在经济和互利的基础上,开发出两国新交易和未来利润交易量和结果改善向量,之前将这些方法与适用于法国和中国目前的社会经济的未利用或新经济指标挂钩。该分析的产出将被用... 详细信息

本论文旨在通过对目前公司使用的低效趋势和方法的分析和批评,在经济和互利的基础上,开发出两国新交易和未来利润交易量和结果改善向量,之前将这些方法与适用于法国和中国目前的社会经济的未利用或新经济指标挂钩。该分析的产出将被用作在商业和贸易导向方法领域的进一步发展的基础,并且在实际的方面,建立更一致的贸易战略以供FnB公司使用,也由其他。

关键词：口味适应趋势演变文化障碍进口转换

Nuclear Aurora kinase A triggers programmed death-ligand 1-mediated immune suppression by activating MYC transcription in triple-negative breast cancer

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Cancer Communications 2021年第9期41卷 851-866页

作者： Shulan Sun Wei Zhou Xiaoxi Li Fei Peng Min Yan Yajing Zhan Fan An Xiaoyan Li Yunyong Liu quentin Liu Haozhe Piao Central Laboratory Cancer Hospital of China Medical UniversityDalian Medical University Clinical Oncology CollegeLiaoning Cancer Hospital&InstituteShenyangLiaoning 110042P.R.China Institute of Cancer Stem Cell Dalian Medical UniversityDalianLiaoning 116044P.R.China State Key Laboratory of Oncology in South China Sun Yat-sen University Cancer CenterGuangzhouGuangdong 510060P.R.China Department of Pathology Cancer Hospital of China Medical UniversityLiaoning Cancer Hospital and instituteShenyangLiaoning 110042P.R.China Department of Cancer Prevention and Treatment Cancer Hospital of China Medical UniversityLiaoning Cancer Hospital&InstituteShenyangLiaoning 110042P.R.China Department of Neurosurgery Cancer Hospital of China Medical UniversityLiaoning Cancer Hospital&InstituteShenyangLiaoning 110042P.R.China

Background:Increasing studies have reported that oncogenes regulate components of the immune system,suggesting that this is a mechanism for *** kinase A(AURKA),a serine/threonine kinase,is involved in cell mitosis and is essential for tumor cell proliferation,metastasis,and drug ***,the mechanism by which AURKA is involved in immune response regulation is ***,this study aimed to investigate the role of AURKA in immune regulation in triple-negative breast cancer(TNBC).Methods:Peripheral blood mononuclear cells(PBMCs)were co-cultured with TNBC *** xCELLigence Real-Time Cell Analyzer-MP system was used to detect the killing efficiency of immune cells on TNBC *** expression of immune effector molecules was tested by quantitative real-time polymerase chain reaction(qRT-PCR)to evaluate immune ***,to validate AURKA-regulated immune response in vivo,4T1 murine breast cancer cell line with AURKA overexpression or downregulation was engrafted into BALB/c *** distribution and proportion of immune cells in tumors were further evaluated by immunohistochemistry and flow ***:Downregulation of AURKA in TNBC cells increased immune response by activating CD8^(+)T cell proliferation and *** rather than cytoplasmic AURKA-derived programmed death-ligand 1(PD-L1)expression was independent of its kinase *** investigations showed that nuclear AURKA increased PD-L1 expression via an MYC-dependent ***-L1 overexpression mostly reversed AURKA silencing-induced expression of immune effector molecules,including interleukin-(IL-2),interferon-γ(IFN-γ),and ***,AURKA expression was negatively correlated with the enrichment and activity of tumor-infiltrating CD8^(+)T cells in 4T1 engrafted BALB/c mouse ***:Nuclear AURKA elevated PD-L1 expression via an MYCdependent pathway and contributed to immune evasion in *** targeting nuclear AU

关键词： Aurora kinase A immune evasion immunotherapy MYC programmed death-ligand 1 triplenegative breast cancer

Geometric optimization model for the solar cavity receiver with helical pipe at different solar radiation

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Frontiers in Energy 2019年第2期13卷 284-295页

作者： Chongzhe ZOU Huayi FENG Yanping ZHANG quentin FALCOZ Cheng ZHANG Wei GAO School of Energy and Power Engineering Huazhong University of Science and TechnologyWuhan 430074China China-EU Institute for Clean and Renewable Energy Huazhong University of Science and TechnologyWuhan 430074China School of Energy and Power Engineering China-EU Institute for Clean and Renewable EnergyHuazhong University of Science and TechnologyWuhan 430074China PROMES-CNRS Laboratory 7 rue du Four Solaire66120 Font-Romeu-Odeillo-viaFrance

In consideration of geometric parameters, several researches have already optimized the thermal efficiency of the cylindrical cavity receiver. However, most of the optimal results have been achieved at a fixed solar radiation. At different direct normal irradiance (DNI), any single optimal result may not be suitable enough for different regions over the world. This study constructed a 3-D numerical model of cylindrical cavity receiver with DNI variation. In the model of a cylindrical cavity receiver containing a helical pipe, the heat losses of the cavity and heat transfer of working medium were also taken into account. The simulation results show that for a particular DNI in the range of 400 W/m2 to 800 W/m2, there exists a best design for achieving a highest thermal efficiency of the cavity receiver. Besides, for a receiver in constant geometric parameters, the total heat losses increases dramatically with the DNI increasing in that range, as well as the temperature of the working medium. The thermal efficiency presented a different variation tendency with the heat losses, which is 2.45% as a minimum decline. In summary, this paper proposed an optimization method in the form of a bunch of fitting curves which could be applied to receiver design in different DNI regions, with comparatively appropriate thermal performances.

关键词： cylindrical cavity receiver 3-D numerical simulation geometric optimization direct normal irradia-tion