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侧流层析试纸在生物及食品安全检测中的研究进展

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国际生物医学工程杂志 2017年第5期40卷 315-322页

作者：李巧凤任舒悦吕全军高志贤军事医学科学院卫生学环境医学研究所天津市环境与食品安全风险监控技术重点实验室天津300050 郑州大学公共卫生学院 450001

侧流层析试纸分析是一种新兴的快速检测传感技术,与耗费高、操作复杂、检测环境要求高的理化检测方法相比,该方法成本低廉、便捷快速,更能满足质量安全监督与现场快速筛查的需求.介绍了侧流层析试纸的检测方法、标记材料的分类及其在各... 详细信息

侧流层析试纸分析是一种新兴的快速检测传感技术,与耗费高、操作复杂、检测环境要求高的理化检测方法相比,该方法成本低廉、便捷快速,更能满足质量安全监督与现场快速筛查的需求.介绍了侧流层析试纸的检测方法、标记材料的分类及其在各领域的实际应用;着重对侧流层析试纸应用于生物及食品安全检测方面的研究进展进行了综述,其中列举了该技术目前的研究现状和优势,也剖析了其存在的瓶颈及未来的发展方向,为今后对试纸条快检技术的深入研究和普遍应用提供了参考价值.

关键词：侧流层析试纸生物检测食品安全

BMI诊断某社区汉族老年人肌肉衰减综合征的价值

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郑州大学学报（医学版） 2017年第2期52卷 201-204页

作者：游杰薄亚聪王萌萌吉喆杨瑞红段丹丹朱艺伟崔晗吕全军郑州大学公共卫生学院营养与食品卫生学教研室郑州450001 郑州市济源路社区卫生服务中心郑州450041

目的:评价体重指数(BMI)作为筛检老年人肌肉衰减综合征指标的应用价值。方法:参照肌肉衰减综合征亚洲工作组制定的诊断标准对郑州市上街区1 287例60岁以上汉族老年人进行肌肉衰减综合征的临床诊断,并依此分为患病组和未患病组。使用受... 详细信息

目的:评价体重指数(BMI)作为筛检老年人肌肉衰减综合征指标的应用价值。方法:参照肌肉衰减综合征亚洲工作组制定的诊断标准对郑州市上街区1 287例60岁以上汉族老年人进行肌肉衰减综合征的临床诊断,并依此分为患病组和未患病组。使用受试者工作特征(ROC)曲线对BMI诊断郑州市上街区汉族老年人肌肉衰减综合征的价值进行评价。结果:未患病组老年男、女的BMI值分别为(25.94±3.10)和(26.44±3.43)kg/m2,患病组老年男、女的BMI值分别为(22.06±2.56)和(22.74±2.77)kg/m2。患病组老年人的BMI明显低于未患病组(P<0.001)。BMI用于诊断老年男、女肌肉衰减综合征的ROC曲线下面积(AUC)分别为0.834(0.769~0.899)和0.804(0.757~0.850),此时的灵敏度和特异度分别为73.2%、82.2%和78.2%、73.1%,对应的切点值则分别为23.0、24.3 kg/m2。结论:BMI测量简单易行,可以用于汉族老年人肌肉衰减综合征的快速筛检。

关键词： BMI 肌肉衰减综合征生物电阻抗法 ROC曲线

四种炎症标志物对HBV相关原发性肝癌术后预后的预测价值

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郑州大学学报（医学版） 2018年第1期53卷 93-97页

作者：崔晗朱艺伟游杰姚明解薄亚聪张玲赵二江崔玲玲吕全军郑州大学公共卫生学院营养与食品卫生学教研室郑州450001 北京大学基础医学院病原生物学系北京100191 郑州大学附属肿瘤医院肝胆外科郑州450003 郑州大学附属肿瘤医院病案室郑州450003

目的:探讨术前外周血中性粒细胞与淋巴细胞比值(NLR)、血小板与淋巴细胞比值(PLR)、单核细胞与淋巴细胞比值(MLR)、预后营养指数(PNI)等炎症标志物与乙肝病毒(HBV)相关原发性肝癌患者根治性切除术后预后的关系。方法:回顾性分析接受根... 详细信息

目的:探讨术前外周血中性粒细胞与淋巴细胞比值(NLR)、血小板与淋巴细胞比值(PLR)、单核细胞与淋巴细胞比值(MLR)、预后营养指数(PNI)等炎症标志物与乙肝病毒(HBV)相关原发性肝癌患者根治性切除术后预后的关系。方法:回顾性分析接受根治性切除术的331例HBV相关原发性肝癌患者的临床及随访资料,计算NLR、PLR、MLR、PNI值。采用Kaplan-Meier法和Cox回归分析影响患者生存的因素。结果:NLR、PLR、MLR、PNI的界值分别为2.41、106.80、0.24、45。根据界值将患者分为高低两组。多因素分析显示,门静脉癌栓、术前AFP、AST、肝内播散及NLR是影响HBV相关原发性肝癌患者根治术后生存的独立危险因素,HR(95%CI)分别为2.652(1.863~3.776)、1.476(1.027~2.120)、1.437(1.047~1.972)、1.596(1.065~2.390)和1.563(1.077~2.268),PNI是此类患者术后生存的保护因素,HR(95%CI)为0.657(0.468~0.922)(P均<0.05)。结论:术前NLR及PNI与HBV相关原发性肝癌患者术后生存有关,低NLR及高PNI的患者预后较好。

关键词：炎症原发性肝癌预后

基于Fine-Gray竞争风险模型预测老年肺结核结核特异死亡的列线图的构建

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郑州大学学报（医学版） 2023年第3期58卷 367-372页

作者：谷若画吕全军任鹏飞王重建毛振兴霍文倩牛恺琳陈裕李琳琳郑州大学公共卫生学院卫生统计学教研室郑州450001 郑州大学第一附属医院营养科郑州450052 郑州市第六人民医院结核病科郑州450015 郑州大学公共卫生学院流行病学教研室郑州450001 郑州大学公共卫生学院环境卫生学教研室郑州450001

目的:建立预测老年肺结核结核特异性死亡的列线图模型。方法:选取2015年1月至2021年2月在河南省14家传染病医院确诊肺结核的544例老年(≥65岁)患者,随机分为训练集(n=435)和验证集(n=109)。在训练集中,利用累积发生函数(CIF)评估患者结... 详细信息

目的:建立预测老年肺结核结核特异性死亡的列线图模型。方法:选取2015年1月至2021年2月在河南省14家传染病医院确诊肺结核的544例老年(≥65岁)患者,随机分为训练集(n=435)和验证集(n=109)。在训练集中,利用累积发生函数(CIF)评估患者结核特异性死亡3 a和5 a的累积发生率。以结核特异性死亡为研究终点,采用Fine-Gray竞争风险模型筛选预后预测因素。绘制列线图,采用一致性指数(C指数)和校准曲线在训练集与验证集数据中评估模型预测性能。结果:训练集数据中结核特异性死亡3 a和5 a的累积发生率分别为9.0%、9.7%。Fine-Gray竞争风险模型分析结果显示年龄、治疗类型、胸片空洞和血清白蛋白水平是老年肺结核患者结核特异性死亡的预测因素,由此构建的列线图在训练集和验证集中,预测的C指数(95%CI)分别为0.815(0.798~0.832)和0.851(0.805~0.897),校准曲线显示预测的3 a和5 a死亡率与实际死亡率有着较好的一致性。结论:Fine-Gray竞争风险模型能有效识别老年肺结核结核特异性死亡的影响因素,以此为依据构建的列线图模型能有效预测患者预后。

关键词：肺结核结核特异性死亡竞争风险模型列线图

Carbon dots-based nanocomposites for heterogeneous photocatalysis

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Journal of Materials Science & Technology 2024年第8期175卷 244-257页

作者： Zhihan Yu Fang Li quanjun Xiang State Key Laboratory of Electronic Thin Film and Integrated Devices School of Electronic Science and EngineeringUniversity of Electronic Science and Technology of ChinaChengdu 610054China Yangtze Delta Region Institute(Huzhou) University of Electronic Science and Technology of ChinaHuzhou 313001China

Carbon dots(CDs),as a class of promising and multifunctional carbon nanomaterials,have become a research hotspot in the field of photocatalysis owning to strong absorption of visible light,favorable photoelectric properties,and tunable energy-level *** numerous efforts have been made to improve photocatalytic performance by combining CDs with other semiconductors in recent years,the summary of enhancement mechanisms for this emerging technology is few *** understanding the synergistic effect of CDs and nanomaterials in photocatalytic applications is extremely important for the further development of photocatalysis in the ***,the photocatalytic mechanism of carbon dots/nanomaterial system is *** typical carbon dots-synergistic enhancement effects are highlighted,namely,energy band regulation,local electric construction,active site engineering,and multiple carrier ***,the recent progress of carbon dots-based nanocomposites in efficient solar energy conversion is reviewed and examples are ***,the future research development direction and challenges are emphasized on this basis.

关键词： Carbon dots Carbon dots-based nanocomposites Synergistic effect Photocatalytic enhancement mechanism Photocatalytic application

Ag_(2)S Quantum Dots Decorated on Porous Cubic-CdS Nanosheets-assembled Flowers for Photocatalytic CO_(2)Reduction

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Chinese Journal of Structural Chemistry 2022年第6期41卷 39-47页

作者： Wei Fu Jiajie Fan quanjun Xiang State Key Laboratory of Electronic Thin Film and Integrated Devices School of Electronic Science and EngineeringUniversity of Electronic Science and Technology of ChinaChengdu 610054China School of Materials Science and Engineering Zhengzhou UniversityZhengzhou 450001China

The production of renewable fossil fuels such as CH_(4) and CO by photocatalytic CO_(2)reduction has attracted more and more ***,single photocatalyst is less efficient for photocatalytic reduction of CO_(2)due to the fast recombination of photogenerated electron ***,we successfully prepare CdS-Ag_(2)S composite by assembling the Ag_(2)S QDs cocatalyst on the surface of CdS nanosheet-assembled flower through oil-bath solvothermal *** composite is prepared through a simple self-assembly strategy using cadmium chloride,ammonia and thiourea as precursors of the CdS nanosheet-assembled flower and silver nitrate and 3-mercaptopropionic acid as the precursors of Ag_(2)S *** average diameter of Ag_(2)S QDs is apparently 6.0 *** light absorption edge of the composite is at around 560 nm,with the corresponding band gap at 2.14 *** CdS-Ag_(2)S QDs composite with 5 wt%Ag_(2)S QDs loaded achieves CO evolution rate of 16.6μmol·g^(-1)·h^(-1)without noble-metal *** strengthened photocatalytic performance and photocatalytic stability were attributed to the energy band broadening of Ag_(2)S QDs caused by quantum size effect and the large specific surface area due to the assembled *** mechanism underlying the enhanced photocatalytic CO_(2)reduction activity is further *** study demonstrates that semiconductor-based quantum dots are strong candidates for excellent cocatalysts in photocatalysis.

关键词： CdS nanosheet Ag_(2)S quantum dots(QDs) assembled flower structure composite materials photocatalytic CO_(2)reduction

Learning real-time search on c-space GVDs

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Frontiers of Computer Science 2017年第6期11卷 1036-1049页

作者： quanjun YIN Long QIN Yong PENG Wei DUAN College of Information System and Management National University of Defense Technology Changsha 410073 China

In the context of robotics, configuration space （c- space） is widely used for non-circular robots to engage tasks such as path planning, collision check, and motion planning. In many real-time applications, it is important for a robot to give a quick response to the user＇s command. Therefore, a constant bound on planning time per action is severely im- posed. However, existing search algorithms used in c-space gain first move lags which vary with the size of the under- lying problem. Furthermore, applying real-time search algo- rithms on c-space maps often causes the robots being trapped within local minima. In order to solve the above mentioned problems, we extend the learning real-time search （LRTS） algorithm to search on a set of c-space generalized Voronoi diagrams （c-space GVDs）, helping the robots to incremen- tally plan a path, to efficiently avoid local minima, and to ex- ecute fast movement. In our work, an incremental algorithm is firstly proposed to build and represent the c-space maps in Boolean vectors. Then, the method of detecting grid-based GVDs from the c-space maps is further discussed. Based on the c-space GVDs, details of the LRTS and its implemen- tation considerations are studied. The resulting experiments and analysis show that, using LRTS to search on the c-space GVDs can 1） gain smaller and constant first move lags which is independent of the problem size; 2） gain maximal clear- ance from obstacles so that collision checks are much re- duced; 3） avoid local minima and thus prevent the robot from visually unrealistic scratching.

关键词： generalized Voronoi diagrams real-time search,robotics configuration space incremental algorithms

Design and application of active sites in g-C_(3)N_(4)-based photocatalysts

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Journal of Materials Science & Technology 2020年第21期56卷 69-88页

作者： Yang Li Xin Li Huaiwu Zhang Jiajie Fan quanjun Xiang State Key Laboratory of Electronic Thin Film and Integrated Devices School of Electronic Science and EngineeringUniversity of Electronic Science and Technology of ChinaChengdu610054China College of Resources and Environment Huazhong Agricultural UniversityWuhan430070China College of Forestry and Landscape Architecture Key Laboratory of Energy Plants Resource and UtilizationMinistry of AgricultureKey Laboratory of Biomass Energy of Guangdong Regular Higher Education InstitutionsSouth China Agricultural UniversityGuangzhou510642China School of Materials Science and Engineering Zhengzhou UniversityZhengzhou450002China

With the development in photocatalysis field,photocatalysts have received increasing attention due to their important role in environmental pollution and energy *** a nonmetallic photocatalyst,graphitic carbon nitride(g-C3N4)has been widely recognized because of its excellent optical properties,low cost,and environment *** the g-C3N4 intrinsic frameworks,carbon atom tends to be the reducing active site,while nitrogen atom tends to be the oxidizing active site and reducing active site according to the difference of ***,the quantity and quality of these active sites are affected by many factors,including C N covalent bonds,surface properties,*** sites play an important role in photocatalysis;however,this role is not detailed in most *** this review,we proposed the following possible mechanisms of active sites in improving the photocatalytic activity of traditional g-C_(3)N_(4) based on its intrinsic:morphology regulation,carrier migration,surface active treatment,and substrate *** following factors affecting the active sites of g-C_(3)N_(4),including basal engineering and hybrid engineering,were also *** roles of these active sites in improving the photocatalytic activity of g-C_(3)N_(4)-based photocatalytic materials,including morphology regulation,surface treatment,heteroatom doping,and interfacial interaction,were also *** challenges and future development of g-C_(3)N_(4)-based photocatalysts that are rich in active surface sites were also *** review provides an in-depth understanding of g-C_(3)N_(4)-based photocatalysts.

关键词： Graphitic carbon nitride Active sites Photocatalyst Solar fuels

Recent advances in crystalline carbon nitride for photocatalysis

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Journal of Materials Science & Technology 2021年第32期91卷 224-240页

作者： Jingjun Liu Wei Fu Yulong Liao Jiajie Fan quanjun Xiang Yangtze Delta Region Institute(Huzhou)&School of Electronic Science and Engineering University of Electronic Science and Technology of ChinaHuzhou 313001China School of Materials Science and Engineering Zhengzhou UniversityZhengzhou 450002China

Semiconductor photocatalytic technology has become one of the most important means to solve the current energy shortage and environmental pollution. Compared with the traditional photocatalysts, graphite carbon nitride has a wider range of light-harvesting and more stable physical and chemical properties. However, traditional thermally induced polymerization of nitrogen-containing precursors produces the melon-based carbon nitride solids with an amorphous or semi-crystalline structure, resulting in low conductivity and moderate photocatalytic activity. Recently, crystalline carbon nitride has attracted more and more attention in improving photocatalytic performance. Some significant progress regarding crystalline carbon nitride for the preparation of solar-fuel and environmental purification has also been *** review describes the recent advances in the design and synthesis of crystalline carbon nitride photocatalysts. A brief description of the unique physical and chemical properties of crystalline carbon nitride was given. Later, the synthetic and modification strategies are being introduced. Then, the photocatalytic application of crystalline carbon nitride was discussed, mainly including photocatalytic H2 production,photocatalytic CO2 reduction, and photocatalytic degradation of pollutants. Finally, the challenges and future directions of crystalline carbon nitride photocatalysts are briefly introduced.

关键词： Crystalline carbon nitride Design and synthesis Photocatalytic H_(2)production CO_(2)reduction Photocatalytic degradation