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Tissue engineering using mesenchymal stem cells with periosteal wrap for bone defect repair in rabbits

Plastic and Aesthetic Research 2015年第1期2卷 340-345页

作者： Trung-Hau LêThua Dang-Nhat Pham Khanh-Linh Lê Minh-Tuan Lê quang-ton-quyen nguyen Phan-Huy nguyen Ngoc-Vu Tran Ngoc-Luong nguyen Willy Boeckx Albert Demey Department of Plastic Reconstructive and Hand SurgeryCenter of Orthopaedic and Plastic SurgeryHue Central HospitalHue City 531120Vietnam Department of Hematology Hue Central HospitalHue City 531120Vietnam Department of Biology College of SciencesHue UniversityHue City 521120Vietnam Department of Plastic Surgery Brugmann University HospitalUniversitélibre de Bruxelles1020 BrusselsBelgium

Aim:Mesenchymal stem cells(MSCs)are an excellent potential source of cells for bone tissue engineering due to their excellent renewal ability and osteogenic differentiation *** study was designed to evaluate the bone formation properties of a demineralized cancellous bone scaffold seeded with MSCs,with or without periosteum,in a critical size bone defect model in ***:Rabbit culture-expanded bone marrow(BM)-MSCs were seeded onto a human demineralized cancellous bone(HDCB)*** defects measuring 15 mm in length were created in each radius.A total of 56 bone defects in 28 rabbits were randomly assigned to one of the 4 groups for scaffold implantation:Group 1:HDCB graft only;Group 2:periosteum-wrapped HDCB graft;Group 3:HDCB graft seeded with BM-MSCs and Group 4:periosteum-wrapped HDCB graft seeded with *** rabbits were sacrificed 12 weeks after surgery for gross observation,radiological assessment,histological analyses and biomechanical ***:New bone(NB)formation and bone healing were successfully achieved,both radiologically and histologically,on demineralized cancellous bone graft seeded with *** were improved when BM-MSCs were associated with ***:This study demonstrates that repair of bone defects in a rabbit model can be achieved through bone grafting using BM-MSCs,implanted on a demineralized cancellous bone *** formation of NB was optimized when combined with the preservation of periosteum at the site of injury.

关键词： Bone defects bone marrow bone tissue engineering mesenchymal stem cells periosteum

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Scouring of a granular bed by dam break: Experimental study and numerical simulation by a VOF-LPT coupling

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International Journal of Sediment Research 2023年第3期38卷 432-445页

作者： quyen Thi Le nguyen Viet Dung nguyen Patrice Coorevits EPROAD Research Unit University of Picardie Jules Verne IUT of Aisne Hanoi University of Civil Engineering

The first part of the research reported here consists of an experimental campaign to study the scouring of a granular bed(glass beads, sand) induced by a dam break in an open channel. Two configurations are considered: with and without cylinders. In the second part of this study, the volume of fluid method coupled with the shear stress transport turbulent model and the lagrangian particle tracking method is used to simulate the local scour processes. The four-way coupling is realized by considering the drag force and collisions between particles. Using a vortex map and velocity profiles, the flow dynamics and scour pattern can be studied. The current research also focuses on the profiles of the erodible particle bed and the sediment transport rate to study the effects of a cylinder on local scour. The presence of the cylinder increases the experimental erosion depth by up to 42%. It was found that for relatively close particle diameters(2 and 3 mm), a granular bed with larger porosity(larger diameter) erodes the *** and numerically it was found that the center of the granular bed experiences more erosion compared to the channel sides. In the last part of the research, comparisons between the numerical results and the experimental data allowed risk areas to be identified and the roles of porosity,sediment density, and flow dynamics on erosion to be identified.

关键词： Volume of fluid Lagrangian particle tracking Scour Granular bed Cylinder Dam break

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Facile synthesis of FeFe2O4 magnetic nanomaterial for removing methylene blue from aqueous solution

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Progress in Natural Science:Materials International 2019年第6期29卷 648-654页

作者： Van-Phuc Dinh Ngoc quyen Tran nguyen-Que-Tran Le quang-Huy Tran Trinh Duy nguyen Gr EEN), nguyen Tat Thanh University Van Tan Le Future Materials and Devices Laboratory Institute of Fundamental and Applied Sciences Duy Tan University Institute of Applied Materials Science VAST Graduate University of Science and Technology VAST Le Quy Don–LBT Highschool Bien Hoa City Dong Nai province Center of Excellence for Green Energy and Environmental Nanomaterials (CE Industrial University of Ho Chi Minh City

A facile and simple chemical precipitation method was utilized to synthesize FeFe2O4magnetic nanomaterial for removing methylene blue（MB） from aqueous solution. Characterizations of this material were examined by using XRD, SEM, FT-IR, TGA-DTG and BET methods. Factors affecting the uptake of methylene blue, including p H, adsorption time, and MB initial concentration were also studied. The measured data were fitted by using four isotherm models including Langmuir, Freundlich, Sips and Temkin. Results showed that the Sips model offers the best fit to the data. In addition, the monolayer MB adsorption capacity obtained from the Langmuir model was 42.35 mg g-1under the optimal conditions of p H = 10 and adsorption time = 80 min. In particular, the uptake of MB onto FeFe2O4magnetic nanomaterial obtained from the kinetic and mechanism studies of the adsorption was in good agreement with prediction of the pseudo-first-order model, whereas the electrostatic interaction was found to play a primary mechanism.

关键词： FeFe2O4 magnetic nanomaterial Adsorption Methylene blue Adsorption mechanism

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EARLY NEOLITHIC SKULLS IN QUYNH VAN NGHE AN NORTH VIETNAM

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古脊椎动物学报(中英文） 1966年第1期 49-57页

作者： nguyen DUY nguyen quang quyen Section of Anthropology Institute of Archaeology Vietnam Section of Anatomy Faculty of Medicine Vietnam

In the beginning of 1964,our archaeologists excavated the old cemetery in Quynh van,and found 30 graves,in which 2 calva were rather well *** calva “Q.V.M.15”was exhumed with a mandible,2 very simple ceramics and 3 flakes,in the *** calva “Q.V.M.17”was exhumed in the grave *** to the Vietnamese Institute of Archaeology it is an ancient cemetery ina kjokkenmoding,in Quynh Van,Ngh

关键词： very than EARLY NEOLITHIC SKULLS IN QUYNH VAN NGHE AN NORTH VIETNAM

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Development of deep neural network model to predict the compressive strength of FRCM confined columns

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Frontiers of Structural and Civil Engineering 2022年第10期16卷 1213-1232页

作者： Khuong LE-nguyen quyen Cao MINH Afaq AHMAD Lanh Si HO Department of Civil Engineering University of Transport TechnologyHanoi 100000Vietnam Faculty of Arts and Design University of CanberraBruce ACT 2617Australia Department of Civil Engineering University of Engineering and TechnologyTaxila 47080Pakistan Graduate School of Advanced Science and Engineering Hiroshima UniversityHiroshima 739-8527Japan

The present study describes a reliability analysis of the strength model for predicting concrete columns confinement influence with Fabric-Reinforced Cementitious Matrix(FRCM).through both physical models and Deep Neural Network model(artificial neural network(ANN)with double and triple hidden layers).The database of 330 samples collected for the training model contains many important parameters,i.e.,section type(circle or square),corner radius rc,unconfined concrete strength fco,thickness nt,the elastic modulus of fiber Ef,the elastic modulus of mortar *** results revealed that the proposed ANN models well predicted the compressive strength of FRCM with high prediction *** ANN model with double hidden layers(APDL-1)was shown to be the best to predict the compressive strength of FRCM confined columns compared with the ACI design code and five physical ***,the results also reveal that the unconfined compressive strength of concrete,type of fiber mesh for FRCM,type of section,and the corner radius ratio,are the most significant input variables in the efficiency of FRCM confinement *** performance of the proposed ANN models(including double and triple hidden layers)had high precision with R higher than 0.93 and RMSE smaller than 0.13,as compared with other models from the literature available.

关键词： FRCM deep neural networks confinement effect strength model confined concrete

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Novel Soft ComputingModel for Predicting Blast-Induced Ground Vibration in Open-Pit Mines Based on the Bagging and Sibling of Extra Trees Models

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Computer Modeling in Engineering & Sciences 2023年第3期134卷 2227-2246页

作者： quang-Hieu Tran Hoang nguyen Xuan-Nam Bui Department of Surface Mining Mining FacultyHanoi University of Mining and GeologyHanoi100000Vietnam Innovations for Sustainable and Responsible Mining(ISRM)Research Group Hanoi University of Mining and GeologyHanoi100000Vietnam

This study considered and predicted blast-induced ground vibration(PPV)in open-pit mines using bagging and sibling techniques under the rigorous combination of machine learning ***,four machine learning algorithms,including support vector regression(SVR),extra trees(ExTree),K-nearest neighbors(KNN),and decision tree regression(DTR),were used as the base models for the purposes of combination and PPV initial *** bagging regressor(BA)was then applied to combine these base models with the efforts of variance reduction,overfitting elimination,and generating more robust predictive models,abbreviated as BA-ExTree,BAKNN,BA-SVR,and *** is emphasized that the ExTree model has not been considered for predicting blastinduced ground vibration before,and the bagging of ExTree is an innovation aiming to improve the accuracy of the inherently ExTree model,as *** addition,two empirical models(i.e.,USBM and Ambraseys)were also treated and compared with the bagging models to gain a comprehensive *** this aim,we collected 300 blasting events with different parameters at the Sin quyen copper mine(Vietnam),and the produced PPV values were also *** were then compiled as the dataset to develop the PPV predictive *** results revealed that the bagging models provided better performance than the empirical models,except for the BA-DTR *** those,the BA-ExTree is the best model with the highest accuracy(i.e.,88.8%).Whereas,the empirical models only provided the accuracy from 73.6%–76%.The details of comparisons and assessments were also presented in this study.

关键词： Mine blasting blast-induced ground vibration environmentally friendly blasting peak particle velocity bagging extra trees

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Effect of land use change on water discharge in Srepok watershed,Central Highland,Viet Nam

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International Soil and Water Conservation Research 2014年第3期2卷 74-86页

作者： nguyen Thi Ngoc quyen nguyen Duy Liem nguyen Kim Loi Tay nguyen University Viet Nam.567 Le Duan streetBuon Ma Thuot CityDak Lak Province Nong Lam University Viet Nam.Linh Trung WardThu Duc districtHo Chi Minh City

Srepok watershed plays an important role in Central Highland in Viet *** impacts to developing social-economic ***,it is necessary to research elements which impact to natural resources in this *** Soil and Water Assessment Tool(SWAT)model and Geography Information System(GIS)were used to simulate water discharge in the Srepok *** objectives of the research were to apply GIS and SWAT model for simulation water discharge and then,we assessed land use change which impacted on water discharge in the *** observed stream flow data from Ban Don Stream gauge station was used to calibrate for the period from 1981 to 2000 and then validate for the period from 2001 to *** using SWAT-CUP software to calibration,NSI reached 0.63 and R square value achieved 0.64 from 2004 to 2008 in calibration and NSI gained good level at 0.74 and R square got 0.75 from 2009 to 2012 in validation step at Ban Don *** that,land cover in 2010 was processed like land cover in 2000 and set up SWAT model *** simulated water discharge in scenario 1(land use 2000)was compared with scenario 2(land use 2010),the simulation result was not significant difference between two scenarios because the change of area of land use was not much enough to affect the fluctuation of water ***,the effect of land cover on water resource could be seen clearly via total water *** percentage of surface flow in 2000 was twice times more than in 2010;retard and base flow in 2000 was slightly more than in ***,decreased surface flow,increased infiltration capacity of water and enriched base flow resulted in the growth of land cover.

关键词： Water discharge Land use change GIS SWAT model Simulations

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Data driven discovery of conjugated polyelectrolytes for optoelectronic and photocatalytic applications

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npj Computational Materials 2021年第1期7卷 641-649页

作者： Yangyang Wan Fernando Ramirez Xu Zhang Thuc-quyen nguyen Guillermo C.Bazan Gang Lu Department of Physics and Astronomy California State University NorthridgeNorthridgeCaliforniaUSA Department of Chemistry and Biochemistry University of CaliforniaSanta BarbaraCaliforniaUSA

Conjugated polyelectrolytes(CPEs),comprised of conjugated backbones and pendant ionic functionalities,are versatile organic materials with diverse ***,the myriad of possible molecular structures of CPEs render traditional,trial-and-error materials discovery strategy ***,we tackle this problem using a data-centric approach by incorporating machine learning with high-throughput first-principles *** systematically examine how key materials properties depend on individual structural components of CPEs and from which the structure–property relationships are *** means of machine learning,we uncover structural features crucial to the CPE properties,and these features are then used as descriptors in the machine learning to predict the properties of unknown ***,we discover promising CPEs as hole transport materials in halide perovskite-based optoelectronic devices and as photocatalysts for water *** work could accelerate the discovery of CPEs for optoelectronic and photocatalytic applications.

关键词： conjugated backbone photocatalytic

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Spectral contrast optical coherence tomography angiography enables single-scan vessel imaging

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Light(Science & Applications) 2019年第1期8卷 1108-1116页

作者： James A.Winkelmann Aya Eid Graham Spicer Luay M.Almassalha The-quyen nguyen Vadim Backman Department of Biomedical Engineering Northwestern UniversityEvanstonIL 60208USA Department of Chemical and Biological Engineering Northwestern UniversityEvanstonIL 60208USA

Optical coherence tomography angiography relies on motion for contrast and requires at least two data acquisitions per pointwise scanning *** present a method termed spectral contrast optical coherence tomography angiography using visible light that relies on the spectral signatures of blood for angiography from a single scan using endogenous *** demonstrate the molecular sensitivity of this method,which enables lymphatic vessel,blood,and tissue discrimination.

关键词： enable signature spectral

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A Cell-Based Smoothed Finite Element Method for Modal Analysis of Non-Woven Fabrics

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Computers, Materials & Continua 2021年第6期67卷 2765-2795页

作者： nguyen T.quyen N.Dourado A.J.P.Gomes F.B.N.Ferreira C2T—Centro de Ciência e Tecnologia Têxtil Departamento de Engenharia TêxtilUniversidade do MinhoCampus de AzurémGuimarães4804-533Portugal CMEMS-UMinho Departamento de Engenharia MecânicaUniversidade do MinhoCampus de AzurémGuimarães4804-533Portugal Department of Computer Science Universidade da Beira InteriorConvento de Sto.AntónioCovilhã6201-001Portugal Instituto de Telecomunicações R.Marquês deÁvila e BolamaCovilhã6201-001Portugal

The combination of a 4-node quadrilateral mixed interpolation of tensorial components element(MITC4)and the cell-based smoothed finite element method(CSFEM)was formulated and implemented in this work for the analysis of free vibration and unidirectional buckling of shell *** formulation was applied to numerous numerical examples of non-woven *** CSFEM schemes do not require coordinate transformation,spurious modes and numerical instabilities are prevented using bilinear quadrilateral element subdivided into two,three and four smoothing *** improvement of the original CSFEM formulation was made regarding the calculation of outward unit normal vectors,which allowed to remove the integral operator in the strain smoothing *** procedure conducted both to the simplification of the developed formulation and the reduction of computational cost.A wide range of values for the thickness-to-length ratio and edge boundary conditions were *** developed numerical model proved to overcome the shear locking phenomenon with success,revealing both reduced implementation effort and computational cost in comparison to the conventional FEM *** cell-based strain smoothing technique used in this work yields accurate results and generally attains higher convergence rate in energy at low computational cost.

关键词： Mindlin-Reissner theory of plates shear-locking gradient/strain smoothing technique non-woven fabric

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