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A Sharding Scheme Based on Graph Partitioning Algorithm for Public Blockchain

Computer Modeling in Engineering & Sciences 2024年第6期139卷 3311-3327页

作者： Shujiang Xu Ziye Wang Lianhai Wang Miodrag J.Mihaljevi′c Shuhui zhang Wei Shao qizheng Wang Key Laboratory of Computing Power Network and Information Security Ministry of EducationShandong Computer Science CenterQilu University of Technology(Shandong Academy of Sciences)Jinan250014China Shandong Provincial Key Laboratory of Computer Networks Shandong Fundamental Research Center for Computer ScienceJinan250014China Mathematical Institute The Serbian Academy of Sciences and ArtsBelgrade11000Serbia

Blockchain technology,with its attributes of decentralization,immutability,and traceability,has emerged as a powerful catalyst for enhancing traditional industries in terms of optimizing business processes.However,transaction performance and scalability has become the main challenges hindering the widespread adoption of blockchain.Due to its inability to meet the demands of high-frequency trading,blockchain cannot be adopted in many scenarios.To improve the transaction capacity,researchers have proposed some on-chain scaling technologies,including lightning networks,directed acyclic graph technology,state channels,and shardingmechanisms,inwhich sharding emerges as a potential scaling technology.Nevertheless,excessive cross-shard transactions and uneven shard workloads prevent the sharding mechanism from achieving the expected aim.This paper proposes a graphbased sharding scheme for public blockchain to efficiently balance the transaction distribution.Bymitigating crossshard transactions and evening-out workloads among shards,the scheme reduces transaction confirmation latency and enhances the transaction capacity of the blockchain.Therefore,the scheme can achieve a high-frequency transaction as well as a better blockchain scalability.Experiments results show that the scheme effectively reduces the cross-shard transaction ratio to a range of 35%-56%and significantly decreases the transaction confirmation latency to 6 s in a blockchain with no more than 25 shards.

关键词： Blockchain sharding graph partitioning algorithm

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One-cycles on Gushel-Mukai fourfolds and the Beauville-Voisin filtration

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Science China Mathematics 2024年第4期67卷 713-732页

作者： Ruxuan zhang School of Mathematical Sciences Fudan UniversityShanghai 200438China

We prove that the invariant locus of the involution associated with a general double EisenbudPopescu-Walter(EPW)sextic is a constant cycle surface and introduce a filtration on CH1of a Gushel-Mukai fourfold.We verify the sheaf/cycle correspondence for sheaves supported on low-degree rational curves,parallel to the case of cubic fourfolds of Shen-Yin’s work.

关键词： Beauville-Voisin ltration irreducible holomorphic symplectic variety Gushel-Mukai fourfold

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Epidemics,Convergence,and Common Prosperity:Evidence from China

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China & World Economy 2021年第6期29卷 117-138页

作者： Zesen Qian Lingran Yuan Shuo Wang qizheng zhang Binlei Gong School of Economics Zhejiang UniversityChina School of Public Affairs Zhejiang UniversityChina Academy of Social Governance and China Academy for Rural Development Zhejiang UniversityChina

This article investigates the impact of previous epidemics on rural development and convergence,and identifies the impacts mechanism based on convergence tests.Using a balanced panel of 31 provinces,the empirical results from 2002 to 2019 show that epidemics decelerated convergence in rural per capita income.The mechanism analysis shows that the accelerated divergence in wages and the decelerated convergence in business income were the major drivers,which also led to decelerated convergence in rural per capita consumption.Although epidemics have not threatened rural food consumption and the Engel coefficient of rural households,these two indicators of basic living needs have failed to achieve convergence across regions.The overall impact of an epidemic on convergence in rural-urban income disparity has also been insignificant,indicating that epidemics have affected rural and urban development simultaneously.Finally,COVID-19 is likely to decelerate convergence in rural income,rural consumption,and urban income.

关键词： common prosperity epidemics regional disparity rural convergence ruralurban disparity

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基于DPCA的涡旋压缩机主轴故障信号调制特性研究

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机床与液压 2024年第10期52卷 201-206页

作者：马桤政张彤赫宋永兴于跃平李奉誉山东建筑大学热能工程学院山东济南250101 压缩机技术国家重点实验室(压缩机技术安徽省实验室) 安徽合肥230031

为了揭示涡旋压缩机的振动和噪声的机制与调制特性,通过搭建实验平台,模拟主轴磨损故障。利用信号解调方法对振动及噪声信号特性进行讨论,探究此类故障对涡旋压缩机的影响。通过与循环平稳分析方法对比,验证了基于时频分析与主成分分析(... 详细信息

为了揭示涡旋压缩机的振动和噪声的机制与调制特性,通过搭建实验平台,模拟主轴磨损故障。利用信号解调方法对振动及噪声信号特性进行讨论,探究此类故障对涡旋压缩机的影响。通过与循环平稳分析方法对比,验证了基于时频分析与主成分分析(DPCA)的信号解调方法处理涡旋压缩机信号的优越性。利用DPCA方法提取涡旋压缩机的信号调制特征,讨论了不同工况下的信号特性及产生机制。结果表明:周期性变化的电磁力与压力增强了主成分中调制频率的幅值,x和y方向的振动对噪声的变化起主导作用。

关键词：涡旋压缩机信号解调故障诊断

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BP神经网络优化Stearns-Noechel模型的羊毛色纺纱配色

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毛纺科技 2024年第4期52卷 111-117页

作者：史帅杰李启正裘柯槟朱杰张斌纪乐福陈维国浙江理工大学纺织科学与工程学院浙江杭州310018 嘉兴南湖学院浙江嘉兴314001 浙江中鼎纺织科技有限公司浙江嘉兴314511 浙江理工大学桐乡研究院有限公司浙江嘉兴314599

为了提升羊毛色纺纱配色的精确度,通过数理统计方法研究颜色特征中的色相、明度、饱和度与Stearns-Noechel模型参数M值之间的关系,采用BP神经网络对Stearns-Noechel模型参数M值进行优化,并与传统的最优平均M值和波长优化M值等方法进行... 详细信息

为了提升羊毛色纺纱配色的精确度,通过数理统计方法研究颜色特征中的色相、明度、饱和度与Stearns-Noechel模型参数M值之间的关系,采用BP神经网络对Stearns-Noechel模型参数M值进行优化,并与传统的最优平均M值和波长优化M值等方法进行对比。结果表明:采用BP神经网络优化Stearns-Noechel模型的配色方法比其他2种传统优化方法在颜色预测精确度上都有提高。在99个羊毛混色纱试验样本中,BP神经网络优化方法得到的平均色差最小,为1.1773,其中色差小于1的样本占54%,结合颜色特征采用BP神经网络优化的Stearns-Noechel模型参数具有较好的效果,对羊毛色纺纱的颜色预测精确度有较大的提高。

关键词：色纺纱 Stearns-Noechel模型 BP神经网络颜色预测颜色特征

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Dynamically-evolved surface heterojunction in iridium nanocrystals boosting acidic oxygen evolution and overall water splitting

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Journal of Energy Chemistry 2023年第3期78卷 374-380,I0011页

作者： Chenyu Yang Xiuxiu zhang qizheng An Meihuan Liu Wanlin Zhou Yuanli Li Fengchun Hu Qinghua Liu Hui Su National Synchrotron Radiation Laboratory University of Science and Technology of ChinaHefei 230029AnhuiChina College of Chemistry and Chemical Engineering Hunan Normal UniversityChangsha 410081HunanChina Fundamental Science on Nuclear Wastes and Environmental Safety Laboratory Southwest University of Science and TechnologyMianyang 621010SichuanChina

Simultaneously realizing improved activity and stability of acidic oxygen evolution reaction(OER) electrocatalysts is highly promising for developing cost-effective sustainable energy in the splitting of water technique.Herein,we report iridium nanocrystals embedded into 3D conductive clothes(Ir-NCT/CC) as a low iridium electrocatalyst realizing ultrahigh acidic OER activity and robust stability.The well-designed Ir-NCT/CC requires a low overpotential of 202 mV to reach the current density of 10 mA cm^(-2)with a high mass activity of 1754 A g^(-1).Importantly,in acidic overall water splitting,Ir-NCT/CC merely delivers a cell voltage of 1.469 V at a typical current density of 10 mA cm^(-2)and also maintains robust durability under continuous operation.We identify that a low working voltage drives the formation of a highly stable amorphous IrOxactive phase over the surface of Ir nanocrystals(surface heterojunction IrOx/Ir-NCT) during operating conditions,which contributes to an effective and durable OER process.

关键词： Electrocatalyst Surface heterojunction In-situ synchrotron radiation techniques Reaction kinetics Acidic overall water splitting

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High-throughput“read-on-ski”automated imaging and label-free detection system for toxicity screening of compounds using personalised human kidney organoids

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Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2022年第7期23卷 564-577页

作者： qizheng WANG Jun LU Ke FAN Yiwei XU Yucui XIONG Zhiyong SUN Man ZHAI Zhizhong zhang Sheng zhang Yan SONG Jianzhong LUO Mingliang YOU Meijin GUO Xiao zhang State Key Laboratory of Bioreactor Engineering East China University of Science and TechnologyShanghai200237China Guangzhou Institutes of Biomedicine and Health Chinese Academy of SciencesGuangzhou510530China Bioland Laboratory(Guangzhou Regenerative Medicine and Health Guangdong Laboratory) Guangzhou510320China Hangzhou Cancer Institute Key Laboratory of Clinical Cancer Pharmacology and Toxicology Research of Zhejiang ProvinceAffiliated Hangzhou Cancer HospitalZhejiang University School of MedicineHangzhou310002China

Organoid models are used to study kidney physiology,such as the assessment of nephrotoxicity and underlying disease processes.Personalized human pluripotent stem cell-derived kidney organoids are ideal models for compound toxicity studies,but there is a need to accelerate basic and translational research in the field.Here,we developed an automated continuous imaging setup with the“read-on-ski”law of control to maximize temporal resolution with minimum culture plate vibration.High-accuracy performance was achieved:organoid screening and imaging were performed at a spatial resolution of 1.1µm for the entire multi-well plate under 3 min.We used the in-house developed multi-well spinning device and cisplatin-induced nephrotoxicity model to evaluate the toxicity in kidney organoids using this system.The acquired images were processed via machine learning-based classification and segmentation algorithms,and the toxicity in kidney organoids was determined with 95%accuracy.The results obtained by the automated“read-on-ski”imaging device,combined with label-free and non-invasive algorithms for detection,were verified using conventional biological procedures.Taking advantage of the close-to-in vivo-kidney organoid model,this new development opens the door for further application of scaled-up screening using organoids in basic research and drug discovery.

关键词： Kidney organoid High-throughput microscopy Nephrotoxicity Machine learning

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Identification of heptapeptides targeting a lethal bacterial strain in septic mice through an integrative approach

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Signal Transduction and Targeted Therapy 2022年第8期7卷 3054-3068页

作者： Xiaoyan zhang Shan Li Haihua Luo Shuyue He Huangda Yang Lei Li Tian Tian qizheng Han Jiacong Ye Chenyang Huang Aihua Liu Yong Jiang Guangdong Provincial Key Laboratory of Proteomics State Key Laboratory of Organ Failure ResearchDepartment of PathophysiologySchool of Basic Medical SciencesSouthern Medical UniversityGuangzhou 510515China Department of Respiratory and Critical Care Medicine Nanfang HospitalSouthern Medical UniversityGuangzhouChina

Effectively killing pathogenic bacteria is key for the treatment of sepsis.Although various anti-infective drugs have been used for the treatment of sepsis,the therapeutic effect is largely limited by the lack of a specific bacterium-targeting delivery system.This study aimed to develop antibacterial peptides that specifically target pathogenic bacteria for the treatment of sepsis.The lethal bacterial strain Escherichia coli MSI001 was isolated from mice of a cecal ligation and puncture(CLP)model and was used as a target to screen bacterial binding heptapeptides through an integrative bioinformatics approach based on phage display technology and high-throughput sequencing(HTS).Heptapeptides binding to E.coli MSI001 with high affinity were acquired after normalization by the heptapeptide frequency of the library.A representative heptapeptide VTKLGSL(VTK)was selected for fusion with the antibacterial peptide LL-37 to construct the specific-targeting antibacterial peptide VTK-LL37.We found that,in comparison with LL37,VTK-LL37 showed prominent bacteriostatic activity and an inhibitive effect on biofilm formation in vitro.In vivo experiments demonstrated that VTK-LL37 significantly inhibited bacterial growth,reduced HMGB1 expression,alleviated lesions of vital organs and improved the survival of mice subjected to CLP modeling.Furthermore,membrane DEGP and DEGQ were identified as VTKbinding proteins by proteomic methods.This study provides a novel strategy for targeted pathogen killing,which is helpful for the treatment of sepsis in the era of precise medicine.

关键词： inhibited organs strain

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机器人引导下穿刺引流10~30 mL脑内小血肿的临床研究

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中国现代手术学杂志 2024年第2期28卷 115-119页

作者：丘琪政颜华张光宇凌文峰程凤燕陈兵广东医科大学梅州临床医学院广东梅州514021 梅州市人民医院广东梅州514031 广东医科大学附属医院神经外科广东湛江524001

目的探讨机器人引导下穿刺引流10~30 mL脑内小血肿的临床效果。方法采用回顾性病例对照研究。选取2019年1月至2022年12月在梅州市人民医院接受治疗的83例高血压脑出血患者,依据治疗方法不同分为机器人手术组(观察组)39例和保守治疗组(... 详细信息

目的探讨机器人引导下穿刺引流10~30 mL脑内小血肿的临床效果。方法采用回顾性病例对照研究。选取2019年1月至2022年12月在梅州市人民医院接受治疗的83例高血压脑出血患者,依据治疗方法不同分为机器人手术组(观察组)39例和保守治疗组(对照组)44例。比较两组患者临床效果、住院期间并发症发生情况、住院时间及住院费用、出院时及出院3个月时基础性日常生活能力量表(basic activity of daily living scale,BADL)评分及美国国立卫生研究院卒中量表(National Institute of Health stroke scale,NIHSS)评分。结果①入院时两组NIHSS评分和BADL评分无统计学差异(P>0.05);但出院时、出院3个月随访时观察组NIHSS评分更低(P0.05)。结论机器人引导下穿刺引流10~30 mL脑内小血肿的疗效较好,术后并发症少,操作便捷简单,可促进患者术后功能的恢复,有效提高患者的生活质量。

关键词：高血压脑出血脑内小血肿机器人辅助血肿腔穿刺

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Algebraic Solution for the Forward Displacement Analysis of the General 6-6 Stewart Mechanism

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Chinese Journal of Mechanical Engineering 2016年第1期29卷 56-62页

作者： WEI Feng WEI Shimin zhang Ying LIAO qizheng Automation School Beijing University of Posts and Telecommunications School of Mechanical and Power Engineering Henan Polytechnic University

The solution for the forward displacement analysis（FDA） of the general 6-6 Stewart mechanism（i.e., the connection points of the moving and fixed platforms are not restricted to lying in a plane） has been extensively studied, but the efficiency of the solution remains to be effectively addressed. To this end, an algebraic elimination method is proposed for the FDA of the general 6-6 Stewart mechanism. The kinematic constraint equations are built using conformal geometric algebra（CGA）. The kinematic constraint equations are transformed by a substitution of variables into seven equations with seven unknown variables. According to the characteristic of anti-symmetric matrices, the aforementioned seven equations can be further transformed into seven equations with four unknown variables by a substitution of variables using the Grobner basis. Its elimination weight is increased through changing the degree of one variable, and sixteen equations with four unknown variables can be obtained using the Grobner basis. A 40th-degree univariate polynomial equation is derived by constructing a relatively small-sized 9 × 9 Sylvester resultant matrix. Finally, two numerical examples are employed to verify the proposed method. The results indicate that the proposed method can effectively improve the efficiency of solution and reduce the computational burden because of the small-sized resultant matrix.

关键词： general 6-6 Stewart mechanism forward displacement analysis （FDA） conformal geometric algebra （CGA）,Gr6bner basis Sylvester resultant

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