检索结果-南通市图书馆

Anti-microtubule activity of the traditional Chinese medicine herb Northern Ban Lan(Isatis tinctoria)leads to glucobrassicin

引用

Journal of Integrative Plant Biology 2021年第12期63卷 2058-2074页

作者： Pingyin Guan Jianning Zhou Sergey Girel Xin Zhu marian Schwab Kunxi Zhang qiyan wang-müller Laurent Bigler Peter Nick molecular Cell Biology Botanical InstituteKarlsruhe Institute of TechnologyFritz-Haber-Weg 4Karlsruhe 76131Germany Department of Chemistry University of ZürichWinterthurerstr.190CH-8057ZurichSwitzerland Research Institute of Organic Agriculture FiBL Ackerstrasse 113CH-5070FrickSwitzerland College of Horticulture China Agricultural UniversityBeijing 100193China Institute of Pharmaceutical Sciences of Western Switzerland University of GenevaRue Michel-Servet 1CH-1211Geneva 4Switzerland Swiss Chinese Herbal medicine and Functional Food Innovation Center Mainaustrasse 21CH-8046ZurichSwitzerland

Traditional Chinese medicine(TCm)belongs to the most elaborate and extensive systems of plant-based *** herb Northern Ban Lan(Isatis tinctoria)is famous for its antiviral and anti-inflammatory *** numerous components isolated from *** have been characterized so far,their modes of action have remained ***,we show that extracts from *** exert antimicrotubular *** time-lapse microscopy in living tobacco BY-2(Nicotiana tabacum ***2)cellsexpressing greenfluorescentprotein-tubulin,weuse activity-guided fractionation to screen out the biologically active compounds of *** 54 fractions obtained from either leaves or roots of *** by methanol(meOH/H_(2)O 8:2),or ethyl acetate extraction,one specific methanolic root fraction was selected,because it efficiently and rapidly eliminated *** combination of further purification with ultrahigh-performance liquid chromatography and high-resolution tandem mass spectrometry most of the bioactivity could be assigned to the glucosinolate compound *** can also affect microtubules and induce apoptosis in HeLa *** the light of these findings,the antiviral activity of Northern Ban Lan is discussed in the context of microtubules being hijacked by many viral pathogens for cell-to-cell spread.

关键词： anti-microtubule activity cytoskeleton glucobrassicin high-performance liquid chromatography(HPLC) high-resolution tandem mass spectrometry(HRmS/mS) Isatis tinctoria Northern Ban Lan traditional Chinese medicine(TCm)

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

生态农业和有机农业的创新

引用

中国生态农业学报（中英文） 2021年第3期29卷 423-430页

作者： Urs Niggli qiyan wang-muller Helga Willer Jacques Fuchs Research Institute of Organic Agriculture(FiBL) Vienna A-1010Austria Research Institute of Organic Agriculture(FiBL) Frick CH-5070Switzerland Swiss Chinese Herbal medicine and Functional Food Innovation Center(SwissHerbs) Zürich CH-8008Switzerland

现代农业系统在明显提高产量、保证粮食安全的同时,也对人类健康和地球的可持续性产生了影响。在持续不断的严重环境破坏和自然资源毁坏的背景下,建立可持续的农业生产方式至关重要。生态农业和有机农业是减少生态可持续性和生产力及社... 详细信息

现代农业系统在明显提高产量、保证粮食安全的同时,也对人类健康和地球的可持续性产生了影响。在持续不断的严重环境破坏和自然资源毁坏的背景下,建立可持续的农业生产方式至关重要。生态农业和有机农业是减少生态可持续性和生产力及社会可持续之间权衡关系的重要方法。这两种农业方法都属生态集约化范畴,均具有减少环境污染的巨大潜力;然而,生态农业和有机农业常导致产量降低。虽然产量降低带来的损失可以通过改变人们的饮食习惯来弥补(如减少食物浪费、减少食用精饲料喂养的肉类),但是,由于全球的发展趋势与之相反,因此本文探讨了通过科学研究寻求新的解决方案前景来提高低投入农业系统作物产量的可能性。为权衡生产力与可持续发展的关系,使生态农业和有机农业有助于粮食安全,我们对未来研究提出5点建议:1)农场和田地的景观设计与复合种植模式、2)数字化技术的应用、3)以农田低投入为目标的作物育种、4)农业废弃物的高质量循环利用和5)非化学作物保护。

关键词：生态农业生产力有机农业系统导向性研究

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Effects of axial gap and nozzle distribution on aerodynamic forces of a supersonic partial-admission turbine

引用

Chinese Journal of Aeronautics 2017年第6期30卷 1844-1853页

作者： Jinpeng JIANG Jiawen LI Guobiao CAI Jue wang qiyan LIN School of Astronautics Beihang University Beijing 100083 China System Engineering Division China Academy of Launch Vehicle Technology Beijing 100076 China Beijing Aerospace Propulsion Institute Beijing 100076 China

The turbine in an LH2/LOX rocket engine is designed as a two-stage supersonic partialadmission turbine. Three-dimensional steady and unsteady simulations were conducted to analyze turbine performance and aerodynamic forces on rotor blades. Different configurations were employed to investigate the effects of the axial gap and nozzle distribution on the predicted performance and aerodynamic forces. Rotor blades experience unsteady aerodynamic forces because of the partial admission. Aerodynamic forces show periodicity in the admission region, and are close to zero after leaving the admission region. The unsteady forces in frequency domain indicate that components exist in a wide frequency region, and the admission passing frequency is *** multiples of the rotational frequency which are multiples of the nozzle number in a fulladmission turbine are notable components. Results show that the turbine efficiency decreases as the axial gap between nozzles and the 1 st stage rotor（rotor 1） increases. Fluctuation of the circumferential aerodynamic force on rotor 1 blades decreases with the axial gap increasing. The turbine efficiency decreases as the circumferential spacing between nozzles increases. Fluctuations of the circumferential and axial aerodynamic forces increase as the circumferential spacing increases. As for the non-equidistant nozzle distribution, it produces similar turbine performance and amplitudefrequency characteristics of forces to those of the normal configuration, when the mean spacing is equal to that of the normal case.

关键词： Aerodynamic force Axial gap Computational fluid dynam-ics (CFD) Nozzle distribution Partial admission Turbine

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Real-time fluorescent quantitative immuno-PCR method for determination of fluoranthene in water samples with a molecular beacon

引用

Journal of Environmental Sciences 2010年第5期22卷 796-800页

作者： qiyan Ye Huisheng Zhuang Chun Zhou Qiong'e wang College of Environmental Science and Engineering Donghua University Shanghai 201620 China School of Environmental Science and Engineering Shanghai Jiao Tong University Shanghai 200240 China College of Chemistry Chemical Engineering and Biotechnology Donghua University Shanhai 201620 China

A reliable and sensitive competitive real-time fluorescent quantitative immuno-PCR （RTFQ-IPCR） assay using a molecular beacon was developed for the determination of trace fluoranthene （FL） in the *** optimized assay conditions,FL can be determined in the concentration range from 1 fg/mL to 100 ng/mL,with y=0.194x ＋ 7.859,and a correlation coefficient of 0.967 was identified,with a detection limit of 0.6 fg/*** water samples were successfully analyzed,recovery was between 90% and 116%,with intra-day relative standard deviation （RSD） of 6.7%-12.8% and inter-day RSD of 8.4%-15.2%.The results obtained from RTFQ-IPCR were confirmed by ELISA,showing good accuracy and suitability to analyze FL in field *** a highly sensitive method,the molecular beacon-based RTFQ-IPCR is acceptable and promising for providing reliable test results to make environmental decisions.

关键词： fluoranthene real-time fluorescent quantitative irnmuno-PCR molecular beacon

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Scene-adaptive crowd counting method based on meta learning with dual-input network DmNet

引用

Frontiers of Computer Science 2023年第1期17卷 91-100页

作者： Haoyu ZHAO Weidong mIN Jianqiang XU Qi wang Yi ZOU qiyan FU School of Information Engineering Nanchang UniversityNanchang 330031China School of Software Nanchang UniversityNanchang 330047China Jiangxi Key Laboratory of Smart City Nanchang 330047China

Crowd counting is recently becoming a hot research topic, which aims to count the number of the people in different crowded scenes. Existing methods are mainly based on training-testing pattern and rely on large data training, which fails to accurately count the crowd in real-world scenes because of the limitation of model’s generalization capability. To alleviate this issue, a scene-adaptive crowd counting method based on meta-learning with Dual-illumination merging Network (DmNet) is proposed in this paper. The proposed method based on learning-to-learn and few-shot learning is able to adapt different scenes which only contain a few labeled images. To generate high quality density map and count the crowd in low-lighting scene, the DmNet is proposed, which contains multi-scale Feature Extraction module and Element-wise Fusion module. The multi-scale Feature Extraction module is used to extract the image feature by multi-scale convolutions, which helps to improve network accuracy. The Element-wise Fusion module fuses the low-lighting feature and illumination-enhanced feature, which supplements the missing illumination in low-lighting environments. Experimental results on benchmarks, WorldExpo’10, DISCO, USCD, and mall, show that the proposed method outperforms the existing state-of-the-art methods in accuracy and gets satisfied results.

关键词： crowd counting meta-learning scene-adaptive Dual-illumination merging Network

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Effective approaches for enhancing the stability of ruthenium-based electrocatalysts towards acidic oxygen evolution reaction

引用

Chinese Chemical Letters 2024年第10期35卷 126-138页

作者： qiyan Wu Ruixin Zhou Zhangyi Yao Tanyuan wang Qing Li State Key Laboratory of materials Processing and Die&mould Technology School of Materials Science and EngineeringHuazhong University of Science and TechnologyWuhan430074China

Water splitting with proton exchange membrane water electrolyzers(PEmWE)is regarded as a promising pathway for sustainable hydrogen ***,oxygen evolution reaction(OER)is considered as the dominant factor during the whole process due to the sluggish *** the catalysts,Rubased catalysts draw special attention because of their excellent activity and relatively low ***,the limited stability impedes their further commercialization and tremendous efforts have been devoted to overcome this *** review firstly introduces the basic mechanisms of *** the evaluation protocols and techniques to investigate the stability of Ru-based catalysts are summarized.A detailed elucidation of the possible degradation mechanisms is also critically ***,effective strategies to design durable Ru-based catalysts for acidic OER are *** as heteroatom doping,phase and facet engineering,heterostructure building and support ***,promises,perspectives and challenges in developing highly durable Ru-based catalysts for acidic OER are outlined.

关键词： Acidic oxygen evolution Ru-based catalysts Stability Degradation mechanisms Optimization strategies

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Growth characteristics and metabonomics analysis of Lactobacillus rhamnosus GG in Ganoderma lucidum aqueous extract medium

引用

Food Bioscience 2023年第3期53卷 564-573页

作者： Yuchen Liu Di Zhang qiyan Ning Jihua wang School of Life Science and Technology Harbin Normal UniversityHarbin150025China Heilongjiang Agricultural Economy Vocational College Mudanjiang157041China

Ganoderma lucidum,with a long history of medicinal use and good nutritional value,is regarded as a health *** *** fruiting body extract has been proposed as a fermentation medium to promote the growth of probiotic organisms such as ***,the effects of *** on the bioactivity and fermentation metabolites of Lactobacillus rhamnosus GG(LGG)require further *** this study,the effects of *** aqueous extract(GLE)on the growth of LGG were *** the 48-h fermentation,lactic acid content increased from 0 to 4.64 mg/ml and the pH was reduced from 5.8 to *** effect of GLE on the key metabolites of LGG was analyzed using non-targeted metabonomics based on LC-mS/*** analysis identified pyrocatechuic acid,taurocholic acid,estradiol and other differential metabolites with clear physiological *** metabolites were significantly enriched over 10 metabolic pathways including pyrimidine metabolism,tyrosine metabolism,alanine,aspartate and glutamate *** metabolites and metabolic pathways propose that LGG has better probiotic effect when fermented with *** findings provide theoretical support for the application of *** extract to improve Lactobacilli probiotic benefits.

关键词： Ganoderma lucidum Fungi Probiotics Lactobacillus rhamnosus GG metabolome analysis

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Predicting for Power Battery SOC Based on Neural Network 36

Predicting for Power Battery SOC Based on Neural Network

引用

第36届中国控制会议

作者： qiyan Yan Yanning wang mechanical and Electrical Engineering Department Guangdong University of Science ＆ Technology

ISBN: (纸本)9781538629185

Energy crisis and environmental pollution stimulate the rapid development of new energy electric *** state of charge（SOC） is a key parameter of power battery in application,so the accurate estimation is extremely *** affecting the battery SOC are many and complicated,scholars have proposed many methods to estimate SOC,but still does not solve the accuracy and practicability of the demand very *** recent years,intelligent scheme has been successfully applied,but the traditional scheme only consider a single mode of learning,when conditions change,estimation error of SOC is *** paper adopts the intelligent scheme based on BP neural network to model and predict power battery *** the same time,genetic algorithm is used to optimize the network parameters in order to improve the predicting accuracy.

关键词： power battery SOC BP neural network genetic algorithm predicting

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

Silencing the gene encoding C/EBP homologous protein lessens acute brain injury following ischemia/reperfusion

引用

Neural Regeneration Research 2012年第31期7卷 2432-2438页

作者： Fengzhang wang Yuan Zhang Chunke He Tingting wang qiyan Piao Qun Liu Department of Neurology Bethune First Hospital Jilin University Changchun 130021 Jilin Province China Department of Neonatology Bethune First Hospital Jilin University Changchun 130021 Jilin Province China Department of Orthopedics Jilin Hospital of Integrated Traditional and Western Medicine Changchun 130021 Jilin Province China Department of Infectious Diseases Zibo First Hospital Zibo 255200 Shandong Province China Department of Cardiology General Hospital of China National Petroleum Corporation in Jilin Jilin 132021 Jilin Province China

C/EBP homologous protein, an important transcription factor during endoplasmic reticulum stress, participates in cell apoptosis mediated by endoplasmic reticulum stress. Previous studies have shown that C/EBP homologous protein mediates nerve injury during Alzheimer＇s disease, subarachnoid hemorrhage and spinal cord trauma. In this study, we introduced C/EBP homologous protein short hairpin RNA into the brains of ischemia/reperfusion rat models via injection of lentiviral vector through the left lateral ventricle. Silencing C/EBP homologous protein gene expression significantly reduced cerebral infarction volume, decreased water content and tumor necrosis factor-α and interleukin-1β mRNA expression in brain tissues following infarction, diminished the number of TUNEL-positive cells in the infarct region, decreased caspase-3 protein content and increased Bcl-2 protein content. These results suggest that silencing C/EBP homologous protein lessens cell apoptosis and inflammatory reactions, thereby protecting nerves.

关键词： C/EBP homologous protein endoplasmic reticulum stress Alzheimer's disease subarachnoid hemorrhage tumor necrosis factor-α ischemia/reperfusion interleukin-1β cerebral infarction neural regeneration

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Fabrication of bimetallic Ag/Fe immobilized on modified biochar for removal of carbon tetrachloride

引用

Journal of Environmental Sciences 2017年第4期29卷 346-357页

作者： Hongwei Wu qiyan Feng School of Environmental Science and Spatial Informatics China University of Mining and Technology Department of Chemistry Zaozhuang University

As an effective conventional absorbent, biochar exhibited limited adsorption ability toward small hydrophobic molecules. To enhance the adsorption capacity, a novel adsorbent was prepared by immobilizing nanoscale zero-valent iron onto modified biochar（mB） and then the elemental silver was attached to the surface of iron（Ag/Fe/mB）. It＇s noted that spherical Ag/Fe nanoparticles with diameter of 51 nm were highly dispersed on the surface of mB. As the typical hydrophobic contaminant, carbon tetrachloride was selected for examining the removal efficiency of the adsorbent. The removal efficiencies of carbon tetrachloride by original biochar（OB）, Ag/Fe, Ag/Fe/OB and Ag/Fe/mB were fully investigated. It＇s found that Ag/Fe/mB showed higher carbon tetrachloride removal efficiency, which is about 5.5 times higher than that of the OB sample due to utilizing the merits of high adsorption and reduction. Thermodynamic parameters revealed that the removal of carbon tetrachloride by Ag/Fe/mB was a spontaneous and exothermic process, which was affected by solution p H, initial carbon tetrachloride concentration and temperature. The novel Ag/Fe/mB composites provided a promising material for carbon tetrachloride removal from effluent.

关键词： Bimetallic Ag/Fe nanoparticles modified biochar Carbon tetrachloride

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：