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多孔材料抑制氢气爆轰实验装置研究

实验技术与管理 2024年第4期41卷 125-131页

作者：高玉坤赵焕娟冯芊康会峰王秋香北京科技大学土木与资源工程学院北京100083 北华航天工业学院航空宇航学院河北廊坊065000

由于氢气具有点火能低、燃烧范围宽的特性,因此其爆轰产生的破坏力巨大,在氢气输送管道中安装多孔材料,可阻碍氢气爆轰产生的爆轰波的传播。该文搭建了预混气爆轰实验系统,在圆形光滑管道中改变初始压力、多孔材料的孔隙度及材料类型,... 详细信息

由于氢气具有点火能低、燃烧范围宽的特性,因此其爆轰产生的破坏力巨大,在氢气输送管道中安装多孔材料,可阻碍氢气爆轰产生的爆轰波的传播。该文搭建了预混气爆轰实验系统,在圆形光滑管道中改变初始压力、多孔材料的孔隙度及材料类型,研究多孔材料抑制氢气爆轰的性能。使用压力传感器、烟膜和数据采集系统采集爆轰波数据,分析爆轰波的传播速度、侧壁烟膜结果、胞格线与传播方向的夹角以及胞格结构等,得到了多孔材料对氢气爆轰抑制作用的规律,对减轻氢气爆炸事故造成的危害具有理论意义和工程应用价值,有助于推动氢能源的大规模利用。

关键词：预混气爆轰多孔材料侧壁烟膜胞格结构

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PI3K、NF-κB p65蛋白在宫颈癌组织中的表达及其临床意义

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实用癌症杂志 2024年第2期39卷 190-193页

作者：王秋香喻春霞夏小飞河南省直第三人民医院 450000

目的探讨磷脂酰肌醇-3-激酶(PI3K)、真核细胞转录因子κB(NF-κB)p65蛋白在宫颈癌组织中的表达及其临床意义。方法选取宫颈癌患者62例作为研究对象,提取宫颈癌组织及癌旁组织,采用免疫组织化学染色法检测PI3K和NF-κB p65蛋白的表达情况... 详细信息

目的探讨磷脂酰肌醇-3-激酶(PI3K)、真核细胞转录因子κB(NF-κB)p65蛋白在宫颈癌组织中的表达及其临床意义。方法选取宫颈癌患者62例作为研究对象,提取宫颈癌组织及癌旁组织,采用免疫组织化学染色法检测PI3K和NF-κB p65蛋白的表达情况,对比宫颈癌组织和癌旁组织中REG4蛋白和Sp1蛋白阳性情况,分析PI3K和NF-κB p65蛋白表达与宫颈癌临床病理参数的相关性。结果宫颈癌组织中PI3K、NF-κB p65蛋白阳性表达率为62.90%和69.35%,癌旁正常组织中无阳性表达,两组比较,P0.05);FIGOⅢ~Ⅳ期患者PI3K和NF-κB p65阳性表达率为76.92%和82.05%,高于FIGOⅠ~Ⅱ期患者的39.13%和47.83%(P<0.05);不同分化程度患者PI3K和NF-κB p65阳性表达率从高到低依次为低分化(83.33%,94.44%)、中分化(61.11%,63.89%)、高分化(25.00%,37.5%)(P<0.05);淋巴结转移患者的PI3K和NF-κB p65阳性表达率分别为86.96%和95.65%,高于无淋巴结转移患者的48.72%和53.85%(P<0.05);相关性分析显示,宫颈癌患者的PI3K和NF-κB p65表达水平与FIGO分期、淋巴结转移呈正相关,与分化程度呈负相关(P<0.05)。结论宫颈癌组织中PI3K、NF-κB p65蛋白阳性表达率均高于癌旁正常组织,并与FIGO分期、淋巴结转移呈正相关,与分化程度呈负相关,对于宫颈癌诊治具有一定的临床意义。

关键词：宫颈癌磷脂酰肌醇-3-激酶真核细胞转录因子κB 临床病理参数

Comprehensive genomic analysis of early and late-onset hepatocellular carcinoma

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Genes & Diseases 2024年第4期11卷 77-81页

作者： Jialin Yang Chao Chen Song wang Yaru Zhang Jiaohui Pang Yajun wang qiuxiang Ou Hao Jiang Juying Liu Department of Radiation Oncology Sichuan Cancer Hospital&InstituteSichuan Cancer CenterSchool of MedicineUniversity of Electronic Science and Technology of ChinaChengduSichuan 610041China Jinling Hospital Department of OncologyNanjing Medical UniversityNanjingJiangsu 210002China Geneseeq Research Institute Nanjing Geneseeq Technology Inc.NanjingJiangsu 210000China Department of Oncology Haian Hospital of Traditional Chinese MedicineHaianJiangsu 226600China Interventional Therapy Department Jiangsu Cancer Hospital&Jiangsu Institute of Cancer Research&The Affiliated Cancer Hospital of Nanjing Medical UniversityNanjingJiangsu 210009China

Hepatocellular carcinoma(HCC)is the major histologic type of primary liver cancer,accounting for approximately 75%of liver cancer cases.'Despite many advancements in its treatment,the prognosis and drug response of HCC patients are ***,there is an unmet clinical need to explore genomic aberrations underlying early-and lateonset HcC,which might facilitate drug discovery and provide personalized biomarker-driven treatment options for these patients.

关键词： patients prognosis cancer

垦造水田防渗层快速构建工艺研究——以韶关与清远为例

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仲恺农业工程学院学报 2024年第2期37卷 53-59,65页

作者：李嘉寅陈平蔡宝昌王秋香李建华徐若怡宋晓张晖仲恺农业工程学院园艺园林学院广东广州510225 广东省土地开发整治中心广东广州510635

本研究以广东韶关南雄与清远清城2种不同地貌的垦造水田项目地为例,通过注水翻耙、原地灌浆、掺加客土等工艺进行防渗层快速构建和土体特征分析.清城项目地通过掺10%的客土可达到55%的保水率,南雄项目地通过注水翻耙即满足保水要求,保... 详细信息

本研究以广东韶关南雄与清远清城2种不同地貌的垦造水田项目地为例,通过注水翻耙、原地灌浆、掺加客土等工艺进行防渗层快速构建和土体特征分析.清城项目地通过掺10%的客土可达到55%的保水率,南雄项目地通过注水翻耙即满足保水要求,保水率在50%以上.防渗层构建后,清城防渗层的土壤容重在1.55~1.72 g/cm^(3),南雄的在1.53~1.61 g/cm^(3);清城防渗层的土壤质地为壤土,南雄则为砂质壤土,但清城防渗层中大于2 mm粒径的砂粒含量是南雄防渗层的2倍;清城防渗层饱和导水率在0.010~0.020 mm/min;南雄防渗层饱和导水率在0.045~0.113 mm/min.研究证明即使砂质壤土也可通过注水翻耙或掺客工艺满足水田保水要求,使土壤兼具防渗层和耕作层的作用,对于土壤的定性也应该进行更全面的分析,特别是对大粒径砂粒和黏粒含量对防渗层保水效果的考虑.

关键词：垦造水田防渗层土壤质地保水犁底层

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A Simple Method to Synthesize Multi-branched Carbon Fibers Using Cupric Chloride Aqueous Solution as Catalyst Precursor

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Journal of Materials Science & Technology 2014年第9期30卷 917-921页

作者： qiuxiang wang Qian Zhang Liping Chen Liyan Yu Lifeng Dong College of Materials Science and Engineering Qingdao University of Science and Technology Yangzhou Polytechnic Institute Department of Physics Astronomy and Materials Science Missouri State UniversitySpringfield MO 65897 USA

Carbon fibers with multi-branched structures were synthesized by chemical vapor deposition method using cupric chloride as catalyst precursor and acetylene as carbon source at different reaction temperatures. Effects of water vapor and reaction temperature on the growth mode of carbon fibers were investigated. Experimental results demonstrate that initial reaction conditions and temperature are key factors for the formation of different carbon materials. Carbon fibers with typical multi-branched structures can be obtained at 450 ℃ when cupric chloride solution was used as catalyst precursor. X-ray diffraction, field emission scanning electron microscopy, and transmission electron microscopy are used to characterize carbon materials, and the growth mechanisms of multi-branched carbon fibers were discussed.

关键词： Amorphous materials Carbon materials Electron microscopy Microstructure

Experimental Study on Heat Transfer and Pressure Drop of Micro-Sized Tube Heat Exchanger

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Transactions of Tianjin University 2014年第1期20卷 21-26页

作者：王秋香戴传山 Key Laboratory of Efficient Utilization of Low and Medium Grade Energy of Ministry of Education Tianjin University

A micro-sized tube heat exchanger(MTHE) was fabricated, and its performance in heat transfer and pressure drop was experimentally studied. The single-phase forced convection heat transfer correlation on the sides of the MTHE tubes was proposed and compared with previous experimental data in the Reynolds number range of 500—1 800. The average deviation of the correlation in calculating the Nusselt number was about 6.59%. The entrance effect in the thermal entrance region was discussed. In the same range of Reynolds number, the pressure drop and friction coefficient were found to be considerably higher than those predicted by the conventional correlations. The product of friction factor and Reynolds number was also a constant, but much higher than the conventional.

关键词：管式换热器实验数据压降传热微米级摩擦系数雷诺数传递关系

A Fast Algorithm for Phase Grating Preparation by Real Space Method

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Journal of Materials Science & Technology 2001年第2期17卷 240-242页

作者： qiuxiang LIU and Yuanming wang Laboratory of Atomic Imaging of Solids, Institute of Metal Research, Chinese Academy of Sciences, Shengyang 110015, China Qibin YANG and Xiaohong YAN Institute of Modern Physics, Xiangtan University, Xiangtan 411105, China Lab. of Atomic Imaging of Solids Inst. of Metal Res. Chinese Acad. of Sci. Shenyang 110015 China

Making use of this expression to calculate the phase grating in high resolution image simulation can greatly reduce the calculating time. In this paper, the derivation of the expression is introduced, and then the computer routine is explained in details. Finally the potential projection map of Mg44Rh7 along [001] direction is shown as an illustration. All operations are carried out in real space, so we call the calculation method as the real space method.

关键词： A Fast Algorithm for Phase Grating Preparation by Real Space Method

Prognostic ability of the neoadjuvant rectal(NAR)score in long-course concurrent chemoradiotherapy for patients with locally advanced rectal cancer:a retrospective cohort study

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Malignancy Spectrum 2024年第1期1卷 53-63页

作者： Siyi Lu Ran Peng Xianan Li Zhaoyu Chen Yi Zhou Ruize Qu Xin Zhou qiuxiang Zhang Yuxia wang Xuemin Li Tao Sun Hao wang Wei Fu Cancer Center Peking University Third HospitalBeijingChina Department of General Surgery Peking University Third HospitalBeijingChina Department of Radiation Oncology Peking University Third HospitalBeijingChina Department of Radiation Oncology Peking University People's HospitalBeijingChina Department of Basic Medical Sciences Peking University Health Science CenterBeijingChina Shenzhen Health Development Research and Data Management Center ShenzhenChina Department of Clinical Nutrition Peking University Third HospitalBeijingChina

Background:The aims of this study were to evaluate the prognostic ability of the neoadjuvant rectal(NAR)score and to develop and validate a nomogram based on the NAR for patients with locally advanced rectal cancer(LARC)treated with neoadjuvant chemoradiotherapy(nCRT).Methods:In total,307 patients,including 230 patients from the primary cohort and 77 from the external cohort,were enrolled across the two *** associations of the NAR score with the tumor response,tumor control,and clinicopathological parameters were *** analysis was performed in the primary and external cohorts using Kaplan‒Meier *** and multivariate analyses were performed to evaluate the prognostic *** NAR-based nomogram was developed in the primary cohort and validated in the external cohort using the concordance index(C-index),calibration plots,and decision curve analyses(DCAs).Results:Kaplan‒Meier survival analysis revealed that the disease-free survival(DFS)and overall survival(OS)of the NAR>16 group were significantly lower than those of the NAR≤16 group(p<0.001).Multivariate Cox regression analysis identified the NAR score as an independent prognostic factor for both DFS(hazard ratio[HR]=2.484,95%confidence interval[CI]:1.159−5.323,p=0.019)and OS(HR=4.633,95%CI:1.076−19.941,p=0.04).Calibration plots and DCAs showed that NARbased nomograms for DFS and OS were consistent and useful in clinical ***,the C-indexes of the NAR-based nomograms were better than those of the other variables in both the primary and external ***:Our study validates the prognostic role of the NAR score for DFS and *** NAR-based nomogram for OS could accurately predict the outcome of LARC patients by stratifying the risk score accordingly.

关键词： NAR score rectal cancer prognosis nomogram

改良版手术患者隐私保护量表在手术室护士中的验证

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护理与康复 2023年第7期22卷 1-5页

作者：王秋香王莺周渝琼浙江中医药大学浙江杭州310006 浙江大学医学院附属第一医院浙江杭州310003

目的对患者隐私保护量表进行改良,并在手术室护士中检验改良版手术患者隐私保护量表的信度、效度及各条目质量。方法项目研究小组通过对11名专家进行函询与小组讨论最终确定改良版手术患者隐私保护量表。2022年6-7月,采用简单随机抽样... 详细信息

目的对患者隐私保护量表进行改良,并在手术室护士中检验改良版手术患者隐私保护量表的信度、效度及各条目质量。方法项目研究小组通过对11名专家进行函询与小组讨论最终确定改良版手术患者隐私保护量表。2022年6-7月,采用简单随机抽样选取浙江省某三级甲等医院的288名手术室护士进行改良版手术患者隐私保护量表的信效度检验。结果原版患者隐私保护量表中的8个条目被剔除,2个条目被修订,最终改良版手术患者隐私保护量表含19个条目。改良版手术患者隐私保护量表内容效度指数是0.87;探索性因子分析提取了3个主因子,累计方差的贡献率为80.36%;3个因子平均方差抽取量值分别为0.80、0.76和0.74,3个因子的组合信度分别为0.82、0.78和0.76;Cronbach’sα系数为0.982。验证性因子分析所得结果支持探索性因子分析量表结构,相关拟合指数均达标。结论改良版手术患者隐私保护量表信效度良好,临床上可作为了解手术室护士对患者隐私保护情况的评定工具。

关键词：手术室隐私保护量表信度效度