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Clinical Outcome of Internal Fixation and Fusion in the Treatment of Spinal Fractures by Paraspinal Muscular Space Approach

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Journal of Clinical and Nursing Research 2024年第7期8卷 10-15页

作者： Yafei Zhao qiushuang ma Meng Zhang Shengwang Li Yannan Li Chenguang Tian Baoding No.1 Hospital of TCM Baoding 071000Hebei ProvinceChina Baoding No.1 Central Hospital Baoding 071000Hebei ProvinceChina

Objective:To explore the clinical effect of internal fixation and fusion with the paraspinal muscle gap approach in the treatment of spinal fracture ***:104 spinal fracture patients admitted to Central Hospital of TCM from October 2022 to April 2024 were selected as the study subjects and were randomly divided into the control group(n=52)and the observation group(n=52)according to the random number table *** control group was treated with the conventional approach of internal fixation surgery,and the observation group was treated with the paraspinal muscular interspace approach of internal fixation *** two groups’general data,surgical indexes,pain,lumbar spine function,and postoperative complications were ***:The baseline data of the two groups of patients were not statistically significant(all P>0.05)while the intraoperative bleeding,the first postoperative time getting up from bed,and the length of hospital stay of the patients in the observation group were shorter than that of the control group(all P=0.000matic,postoperative lumbar spine function recovery is faster,and can reduce the incidence of postoperative complications.

关键词： Paraspinal muscular interspace approach Fixation and fusion Spinal fracture

Regularized automatic frequency response function acquisition of a milling robot operating in a high-dimensional workspace

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Science China(Technological Sciences) 2024年第6期67卷 1783-1797页

作者： LUO WenLong TANG XiaoWei ma Tao GUO qiushuang XU YanYan YUAN Xing ZHANG Lei maO XinYong School of Mechanical Science and Engineering Huazhong University of Science and TechnologyWuhan430074China State Key Laboratory of Smart manufacturing for Special Vehicles and Transmission System Baotou014030China Wuhan Heavy Duty machine Tool Group Corporation Wuhan430205China

Because robotic milling has become an important means for machining significant large parts,obtaining the structural frequency response function(FRF)of a milling robot is an important basis for machining process ***,because of its articulated serial structure,a milling robot has an enormous number of operating postures,and its dynamics are affected by the motion *** accurately obtain the FRF in the operating state of a milling robot,this paper proposes a method based on the structural modification *** the traditional excitation method,the proposed method uses robot joint motion excitation instead of hammering excitation to realize *** address the problem of the lack of information brought by motion excitation,which leads to inaccurate FRF amplitudes,this paper derives the milling robot regularization theory based on the sensitivity of structural modification,establishes the modal regularization factor,and calibrates the FRF *** to the commonly used manual hammering experiments,the proposed method has high accuracy and reliability when the milling robot is in different *** the measurement can be performed directly and automatically in the operation state,and the problem of inaccurate amplitudes is solved,the proposed method provides a basis for optimizing the machining posture of a milling robot and improving machining efficiency.

关键词： milling robot structural dynamics frequency response function automatic identification modal regularization factor high-dimensional workspace

椎间孔镜靶向单通道髓核摘除术对腰椎融合术后相邻节段椎间盘突出症的临床运用分析

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西部医学 2024年第4期36卷 534-538页

作者：赵亚飞田斌武马秋双张猛田晨光李亚楠李生旺保定市第一中医院骨科河北保定071000 保定市第一中心医院病理科河北保定071000

目的探讨椎间孔镜靶向单通道髓核摘除术(TO-PTED)对腰椎融合术后相邻节段椎间盘突出症(LDH)的临床运用。方法选取2018年1月—2021年3月在我院行TO-PTED的45例腰椎融合术后相邻节段LDH患者为观察组,另随机选取同期在我院行椎板间开窗髓... 详细信息

目的探讨椎间孔镜靶向单通道髓核摘除术(TO-PTED)对腰椎融合术后相邻节段椎间盘突出症(LDH)的临床运用。方法选取2018年1月—2021年3月在我院行TO-PTED的45例腰椎融合术后相邻节段LDH患者为观察组,另随机选取同期在我院行椎板间开窗髓核摘除术的45例腰椎融合术后相邻节段LDH患者为对照组。比较两组患者的围手术期临床资料、手术前后的视觉模拟评分(VAS)、日本骨科协会评分(JOA)、影像学资料,采用改良macNab标准来进行疗效的评价。结果观察组患者的手术时长、术中失血量、住院天数均显著低于对照组,术中X线透视次数、临床优良率显著高于对照组(P0.05)。结论TO-PTED能明显缓解腰椎融合术后相邻节段LDH患者的疼痛状况,促进腰椎功能的恢复,具有创伤小、术中失血量少、术后恢复快等优点,疗效优于传统的椎板间开窗髓核摘除术,可在临床推广应用。

关键词：椎间盘突出症椎间孔镜靶向单通道髓核摘除术临床疗效

Application Experience of Quality Feedback in Standardized Practical Skills Training for Clinicopathology Residents

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Journal of Contemporary Educational Research 2022年第8期6卷 91-95页

作者： qiushuang ma Bingjuan Zhou Jirui Sun Wenming Zhao Jinmei Li Haizhi Qiao Jinku Zhang Department of Pathology Baoding First Central HospitalBaoding 071000Hebei ProvinceChina

In recent years,there are increasingly more standardized trainings for doctors based on the standardized training outline that is suitable for different *** training has gradually formed a relatively sound training *** reflecting students’learning effect,there is a need for an ideal quality feedback system in the standardized practical skills training for clinical pathology *** feedback system can help students achieve the training objectives through understanding and grasping the learning content.

关键词： Quality feedback Clinicopathology Residents Standardized practical skills training

Cotton ethylene response factor Gh ERF91 is involved in the defense against Verticillium dahliae

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Journal of Integrative Agriculture 2024年第10期23卷 3328-3342页

作者： Nurimanguli Aini Yuanlong Wu Zhenyuan Pan Yizan ma qiushuang An Guangling Shui Panxia Shao Dingyi Yang Hairong Lin Binghui Tang Xin Wei Chunyuan You Longfu Zhu Dawei Zhang Zhongxu Lin Xinhui Nie Key Laboratory of Oasis Eco-agriculture Xinjiang Production and Construction Group/Agricultural CollegeShihezi UniversityShihezi 832003China National Key Laboratory of Crop Genetic Improvement/College of Plant Sciences&Technology Huazhong AgriculturalUniversityWuhan 430070China Cotton Research Institute Shihezi Academy of Agricultural ScienceShihezi 832011China Institute of Economic Crops Xinjiang Academy of Agricultural SciencesUrumqi 830091China

Verticillium dahliae causes significant losses in cotton *** reveal the mechanism of the defense response to *** in cotton,transcriptomic analyses were performed using cotton cultivars M138(***-resistant)and P2(***-susceptible).The results revealed 11,076 and 6,640 differentially expressed genes(DEGs)in response to ***,*** weighted gene co-expression network analysis of 4,633 transcription factors(TFs)indicated a“MEblue”module containing 654 TFs that strongly correlate with resistance to *** these TFs,the ethylene response factor Ghi_A05G10166(GhERF91)was identified as a putative hub gene with a defense response against ***.A virus-induced gene silencing assay and exogenous application of ethephon showed that GhERF91 is activated by ethylene and positively regulates the response to *** exposure in *** study provides fundamental transcriptome data and a putative causal gene(GhERF91)associated with resistance to ***,as well as genetic resources for breeding ***-resistant cotton.

关键词： cotton Verticillium wilt RNA-sequencing GhERF91 virus-induced gene silencing

紫荆关流域分布式HEC-HMS水文模型构建及洪水模拟

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灌溉排水学报 2019年第4期38卷 108-115页

作者：康彦付李建柱马秋爽河北省邢台水文水资源勘测局河北邢台054000 天津大学水利工程仿真与安全国家重点实验室天津300350

国内外学者利用HEC-HMS水文模型模拟流域降雨径流过程,发现该模型有良好的适用性。【目的】提高紫荆关流域洪水模拟精度。【方法】采用紫荆关流域水文气象及下垫面资料,将流域划分为11个子流域,通过选择产流和汇流计算方法,构建了该流... 详细信息

国内外学者利用HEC-HMS水文模型模拟流域降雨径流过程,发现该模型有良好的适用性。【目的】提高紫荆关流域洪水模拟精度。【方法】采用紫荆关流域水文气象及下垫面资料,将流域划分为11个子流域,通过选择产流和汇流计算方法,构建了该流域分布式HEC-HMS水文模型,并从历史实测暴雨洪水事件中选择14场洪水对构建的HEC-HMS水文模型进行了参数率定和模型验证。【结果】率定的各子流域产流参数基本相同,由于各子流域面积不同导致汇流参数也不同。模拟的洪峰流量和洪量相对误差均在20%以内,纳什效率系数为0.51～0.95,模拟与实测的洪水过程线吻合较好,模型模拟精度较高。【结论】构建的水文模型能反映紫荆关流域实际的产汇流过程,可用于该流域洪水过程模拟和洪水预报。

关键词：紫荆关流域模型洪水模拟

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泊沙康唑晶型制备及甲醇-水体系中相图测定

中国现代应用药学 2022年第14期39卷 1863-1867页

作者：李宏名张娇吴转马秋爽王天明四川科伦药物研究院有限公司成都611138 随州市中心医院湖北随州441300

目的制备泊沙康唑工艺相关的Form Ⅰ、Form Ⅲ、Form Ⅳ、Form S 4种晶型,研究上述晶型在甲醇-水体系中相互稳定性关系,并绘制相图。方法采用溶液结晶法控制结晶溶剂、温度等析晶条件进行制备,并采用XRPD、DSC、TGA等方法表征4种晶型... 详细信息

目的制备泊沙康唑工艺相关的Form Ⅰ、Form Ⅲ、Form Ⅳ、Form S 4种晶型,研究上述晶型在甲醇-水体系中相互稳定性关系,并绘制相图。方法采用溶液结晶法控制结晶溶剂、温度等析晶条件进行制备,并采用XRPD、DSC、TGA等方法表征4种晶型,采用晶型竞争试验的方法研究晶型在甲醇-水体系中的相对稳定性。结果在甲醇-水体系中,泊沙康唑的晶型与水活度及温度密切相关。高水活度和低温更易于形成Form Ⅳ;高浓度甲醇和低温更易于形成Form Ⅲ;高水活度和高温更易于形成Form S;低水活度和高温更易于形成Form Ⅰ。结论泊沙康唑在原料药结晶工艺及制剂处方工艺过程中存在转晶风险,制剂处方工艺中采用湿法造粒风险较高,因此在结晶工艺过程中确定析晶和洗涤时的甲醇优选范围对原料药和制剂生产过程中的晶型控制具有较强的指导意义。

关键词：泊沙康唑多晶型相图

Detection and Clinical Significance of Peripheral Blood CTC, CA125, CA153, and CEA Levels in Patients with Ductal Carcinoma in situ

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Proceedings of Anticancer Research 2023年第5期7卷 89-94页

作者： Jirui Sun qiushuang ma Hong Chen Xing Zhou Jinku Zhang Baoding First Central Hospital Baoding 071000Hebei ProvinceChina

Objective:To explore the detection and clinical significance of peripheral blood CTC,CA125,CA153,and CEA levels in patients with ***:210 patients who received surgical treatment for breast cancer in our hospital from January 2019 to December 2022 were selected as the research *** to the postoperative pathology,100 cases were divided into breast cancer and 110 benign breast tumor *** hundred ten healthy patients undergoing physical examination during the same period were selected as the control ***153,CA125,and CEA levels were observed in the three ***:The levels of CA153,CA125,and CEA in the breast cancer group were significantly higher than those in the benign breast tumor group and the control group(Pmarkers,CA153 has the highest sensitivity at 39.00%,CA125 has the second highest sensitivity at 18.00%,and CEA has the lowest sensitivity at 17.00%;The sensitivity of the two joint tests of CA153+CA125,CA153+CEA,and CA125+CEA for the diagnosis of breast cancer were 50.00%,48.00%,and 26.00%respectively;the sensitivity of the three joint tests is the highest,reaching 53.00%,while the specificity of the joint tests was lower than the individual ***:Detection of peripheral blood CTC,CA125,CA153,and CEA levels has specific reference significance for the treatment and prognosis of DCIS patients.

关键词： Ductal carcinoma in situ CTC CA125 CA153

Expression of MxA Protein in Triple Negative Breast Cancer and its Relationship with Prognosis

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Proceedings of Anticancer Research 2020年第3期4卷 1-3页

作者： Jinmei Li Jirui Sun Hong Chen qiushuang ma Jinku Zhang Department of Pathology Baoding No.1 Central HospitalBaodingHebei ProvinceChina

Objective:To explore the expression of human myxovirus resistance protein A(MxA)in triple negative breast cancer(TNBC)and its relationship with ***:144 cases of TNBC confirmed by pathology before or after surgery from January 2014 to January 2017 in the First Central Hospital of Baoding City were retrospectively *** blotting was used to detect the expression of MxA protein in TNBC and adjacent breast *** to the expression of MxA protein,144 TNBC patients were divided into low MxA protein expression group(n=91)and MxA protein high expression group(n=53)for subsequent comparison of prognosis of patients in between these two ***:The expression of MxA protein in TNBC tissue was lower than that of adjacent breast tissue,and the difference was statistically significant(P<0.05).The patients in high MxA expression group had higher loco-regional recurrence-free rate,disease-free survival(DFS)rate,and overall survival(OS)rate than those in low MxA expression group for 3 *** the other hand,the distant metastasis rate was lower in the high expression group compared to that in the low MxA expression group,and the difference was statistically significant(P<0.05).Conclusion:In triple-negative breast cancer,high MxA expression is a potential predictor of TNBC prognosis.

关键词： Triple negative breast cancer Human myxovirus resistance protein A Prognosis