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Toxic effects of pesticides on the marine microalga Skeletonema costatum and their biological degradation

Science China Earth Sciences 2023年第3期66卷 663-674页

作者： Zilian ZHANG qiulan chen Bo chen Taojie DONG Meng chen State Key Laboratory of Marine Environmental Science Xiamen UniversityXiamen 361102China Key Laboratory of the Ministry of Education for Coastal and Wetland Ecosystem College of the Environment and EcologyXiamen UniversityXiamen 361102China College of Ocean and Earth Sciences Fujian Key Laboratory of Marine Carbon SequestrationXiamen UniversityXiamen 361102China College of Life Sciences Hebei UniversityBaoding 071000China Quanzhou Environmental Monitoring Center of Fujian Province Quanzhou 362000China

Pesticides are considered to be toxic pollutants that are harmful to the health of humans and animals or dangerous to the *** pesticides chlorpyrifos,acetochlor,and dicofol,representatives of organophosphorus,acyl amide,and organochlorine pesticides,are widely used in agriculture and have been frequently detected in aquatic ***,the toxicity of these pesticides to marine microbes is *** this study,the toxic effects of the three pesticides on a representative marine microalga,the diatom Skeletonema costatum(***),were *** cell density and chlorophyll-a(Chl-a)content were analyzed to investigate the toxic effects after *** was exposed to the three pesticides both individually and in *** N/P ratio in the culture medium and the degradation of the pesticides were also analyzed during *** acute toxicity analysis indicated that the growth of *** was significantly inhibited by acetochlor,followed by the effect of dicofol and *** cell membrane of the microalgae was impaired by *** toxicity analysis indicated that the presence of acetochlor increased the toxicity of dicofol and *** contrast,the presence of dicofol reduced the toxicity of acetochlor and *** N/P ratio in the culture medium was largely increased at late growth stages;however,it was significantly lowered when the microalgae were exposed to chlorpyrifos compared to acetochlor and *** degradation of the pesticides was promoted by microalgae,suggesting that microalgae might contribute to the removal of these pesticides from the marine *** toxic mechanism of the pesticides on the marine microalgae and the fates of pesticides in the ocean need to be further studied.

关键词： Microalgae Pesticide Toxicity Degradation Skeletonema costatum

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Accelerate the Progress Towards Elimination of Dog-Mediated Rabies in China

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China CDC weekly 2021年第39期3卷 813-814页

作者： qiulan chen Division of Infectious Disease Key Laboratory of Surveillance and Early Warning on Infectious DiseaseChinese Center for Disease Control and PreventionBeijingChina

Rabies is an ancient zoonotic disease first recorded over 4,000 years ***,over 99%of human rabies cases were caused by rabid *** is fatal once symptoms ***,rabies is preventable through mass dog vaccination and post-exposure prophylaxis(PEP),including wound treatment,vaccine injection,and passive immunization when *** vaccination coverage of 70%among dog populations can interrupt dogmediated rabies and is regarded as a first-line defense against human rabies for its cost-effectiveness.

关键词： Rabies wound vaccination

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一种新型负压引流器在血浆引流患者中的临床应用效果

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现代养生 2024年第17期24卷 1339-1341页

作者：蒋越陈梅刘旭陈秋兰四川省自贡市第一人民医院

目的观察分析新型负压引流器在术后需持续血浆引流患者中的临床应用效果。方法收集自贡市第一人民医院2022年3月-2023年4月收治入院的90例需血浆引流的患者作为研究对象，根据组间基线资料均衡可比的原则，采用随机数字表法分为对照... 详细信息

目的观察分析新型负压引流器在术后需持续血浆引流患者中的临床应用效果。方法收集自贡市第一人民医院2022年3月-2023年4月收治入院的90例需血浆引流的患者作为研究对象，根据组间基线资料均衡可比的原则，采用随机数字表法分为对照组及观察组，每组各45例。对照组使用普通负压引流器；观察组采用自行设计新型负压引流器。观察两组患者不良事件发生情况、负压引流管细菌感染情况、护士工作满意度评分及患者焦虑程度。结果引流后，观察组患者导管脱落事件发生率明显低于对照组，差异有统计学意义（P0.05）；观察组患者护理满意度明显优于对照组，焦虑程度得分低于对照组，差异有统计学意义（P<0.05）；观察期间，两组患者均未发生负压引流管路细菌感染事件。结论在术后需持续血浆引流患者中，使用自行设计的新型负压引流器能够减少不良事件的发生，减少医院感染发生率和职业暴露，提升护理服务质量和患者满意度，降低患者治疗期的焦虑情绪。

关键词：负压引流临床应用不良事件护理满意度

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Epidemiological Characteristics of Human Brucellosis-China,2016−2019

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China CDC weekly 2021年第6期3卷 114-119,I0002,I0003页

作者： Zhongfa Tao qiulan chen Yishan chen Yu Li Di Mu Huimin Yang Wenwu Yin Division of Infectious Disease Key Laboratory of Surveillance and Early Warning on Infectious DiseaseChinese Center for Disease Control and PreventionBeijingChina Guizhou Provincial Center for Disease Control and Prevention GuiyangGuizhouChina China Field Epidemiology Training Project BeijingChina Emory University AtlantaGAUSA

Introduction:Brucellosis is an important zoonotic infectious disease with its main mode of transmission from livestock to *** study analyzed epidemiological characteristics of human brucellosis from 2016 to 2019 in China,aiming to understand progress of the National Program of Brucellosis Prevention and ***:The research obtained data on human brucellosis cases reported through China’s National Notifiable Disease Reporting System(NNDRS)from January 1,2016 to December 31,2019 and described brucellosis epidemiological patterns by region,seasonality,age,sex,and ***:The number of cases reported nationwide in China decreased from 47,139(3.4/100,000)in 2016 to 37,947(2.7/100,000)in 2018,and then increased to 44,036(3.2/100,000)in 2019,with an average annual incidence of 3.0/100,000 during the four study *** in Xinjiang declined from 35.6/100,000 in 2016 to 16.3/100,000 in 2019-an average annual decrease of 22.9%.Brucellosis in Inner Mongolia increased from 23.8/100,000 in 2016 to 54.4/100,000 in 2019-an average increase of 31.8%per year and accounting for 22%of all reported *** China reported 95.2%of cases during this period and still had an incidence of 7.2/100,000 and 87.0%of counties being affected by brucellosis in *** this region in 2019,males aged 45-64 years old had an incidence of over 15.9/100,000,compared with over 7.0/100,000 among females aged 45-64 years ***:Although there was progress in prevention and control of human brucellosis in some provincial-level administrative divisions(PLADs)in 2016 through 2019,progress was limited nationwide and there was an overall resurgence of brucellosis in *** resurgence was primarily in Inner *** One Health approach should be strengthened to ensure successful and sustainable brucellosis prevention and control in China.

关键词： prevention nationwide occupation

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Assessing Impacting Factors of Dog Owners’Adoption of Dog Vaccination Against Rabies:A Cross-sectional Survey in Rural Areas—Guangxi Zhuang Autonomous Region,China,2021

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China CDC weekly 2021年第42期3卷 883-888页

作者： Ning chen qiulan chen Yanping Zhang Mantong Zhu Wenwu Yin Di Mu Yu Li Yingjie chen Yidan Deng Xianyan Tang School of Public Health Guangxi Medical UniversityNanningGuangxi Zhuang Autonomous RegionChina Division of Infectious Disease Key Laboratory of Surveillance and Early Warning on Infectious DiseaseChinese Center for Disease Control and PreventionBeijingChina Animals Asia ChengduSichuanChina.

Summary What is already known about this topic?Rabies is fatal while *** than 99%of human rabies cases were caused by dog bites *** dog vaccination could interrupt dogmediated rabies if achieving and maintaining a minimum coverage rate of 70%.What does this report contribute?The results of this study show that roughly 23.7%of households owned dogs in Guangxi Zhuang Autonomous Region.

关键词： Rabies sectional Rural

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Awareness Towards Rabies and Exposure Rate and Treatment of Dog-Bite Injuries Among Rural Residents—Guangxi Zhuang Autonomous Region,China,2021

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China CDC weekly 2021年第53期3卷 1139-1142页

作者： Mantong Zhu Di Mu qiulan chen Ning chen Yanping Zhang Wenwu Yin Yu Li Yingjie chen Yidan Deng Xianyan Tang School of Public Health Guangxi Medical UniversityNanningGuangxi Zhuang Autonomous RegionChina Division of Infectious Disease Key Laboratory of Surveillance and Early Warning on Infectious DiseaseChinese Center for Disease Control and PreventionBeijingChina Animals Asia ChengduSichuanChina.

Summary What is already known about this topic?Although fatal once clinical signs appear,rabies is preventable through three proven,effective interventions including mass dog vaccination,postexposure prophylaxis(PEP),and,though sometimes neglected,awareness of *** is added by this report?The total awareness rate of rabies-related knowledge among rural residents was only 57.9%in Guangxi Zhuang Autonomous Region,one of the provinciallevel administrative divisions(PLADs)with endemic rabies in China.

关键词： Rabies Rural neglected

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Epidemiological Survey of First Human Brucellosis Outbreak Caused by the Sika Deer(Cervus nippon)—Guizhou Province,China,2019

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China CDC weekly 2021年第14期3卷 301-303页

作者： Zhongfa Tao Zhangping Yang Yishan chen Shufeng Yang Jingchao Xu Yue Wang Mingyu Lei Yun Gou qiulan chen Yan Huang Guizhou Provincial Center for Disease Control and Prevention GuiyangGuizhouChina Division of Infectious Disease Key Laboratory of Surveillance and Early Warning on Infectious DiseaseChina Center for Disease Control and PreventionBeijingChina China Field Epidemiology Training Project BeijingChina Qiandongnan Prefecture Center for Disease Control and Prevention KailiGuizhouChina Emory University America Leishan County Center for Disease Control and Prevention LeishanGuizhouChina Qiannan Prefecture Center for Disease Control and Prevention DuyunGuizhouChina.

Summary What is already known on this topic?Brucellosis is a zoonotic infectious disease caused by Brucella *** main source of infection in human brucellosis is sick animals,mainly including sheep,goat,and cattle,but sika deer(Cervus nippon)can also cause human *** first human brucellosis case in Guizhou Province was reported in 2009,and no brucellosis outbreak was reported caused by sika deer ever before.

关键词： Guizhou nippon break

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Investigation of Brucellosis Caused by Raw Goat Milk—Fujian Province,China,April–June,2019

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China CDC weekly 2021年第20期3卷 430-433页

作者： Mu Di Zhongfa Tao Weiping Hua Jiandong chen Jingming Cao Yanqin Deng Huihui Liu Lijie Zhang Yishan chen qiulan chen Wenwu Yin Chinese Center for Disease Control and Prevention Infectious Diseases Management OfficeBeijingChina China Chinese Field Epidemiology Training Project BeijingChina Guizhou Provincial Center for Disease Control and Prevention GuiyangGuizhouChina Zhangping County Center for Disease Control ZhangpingFujianChina Fujian Provincial Center for Disease Control and Prevention FuzhouFujianChina Emory University AtlantaUSA.

Summary What is already known about this topic?Brucellosis is one of the most important zoonotic diseases in *** milk and dairy products are essential pathways for foodborne transmission of *** can completely kill Brucella *** milk,and milk-borne transmission is mainly related to unhealthy dietary hygiene habits and insufficient epidemic control among animals.

关键词： China. Fujian Pasteur

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Transmission and mortality risk assessment of severe fever with thrombocytopenia syndrome in China:results from 11-years’study

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Infectious Diseases of Poverty 2022年第5期11卷 30-40页

作者： qiulan chen Dong Yang Yanping Zhang Mantong Zhu Ning chen Zainawudong Yushan Key Laboratory of Surveillance and Early-Warning on Infectious Diseases Chinese Center for Disease Control and PreventionBeijingChina Changsha Center for Disease Control and Prevention ChangshaChina School of Public Health Guangxi Medical UniversityNanningChina Chinese Center for Disease Control and Prevention Changbai RoadChangpingBeijing 102206China.

Background: The transmission and fatal risk of severe fever with thrombocytopenia syndrome (SFTS), an emerging infectious disease first discovered in China in 2009, still needed further quantification. This research aimed to analyze the SFTS clusters and assess the transmission and mortality risk for ***: Both epidemiological investigation and case reports regarding SFTS clusters in China during 2011-2021 were obtained from the Public Health Emergency Information Management System of the Chinese Center for Disease Control and Prevention Information System. The transmission risk was evaluated by using the secondary attack rate (SAR) and relative risk (RR). Mortality risk factors were analyzed using a logistic regression ***: There were 35 SFTS clusters during 2011-2021 involving 118 patients with a fatality rate of 22.0%. The number of clusters annually increased seasonally from April to September. The clusters mainly occurred in Anhui (16 clusters) and Shandong provinces (8 clusters). The SAR through contact with blood or bloody fluids was much higher than that through contact with non-bloody fluids (50.6% vs 3.0%;χ^(2) = 210.97,P < 0.05), with anRR of 16.61 [95% confidence interval (CI): 10.23-26.97]. There was a statistically significant difference in the SAR between exposure to the blood of a deceased person during burial preparation and exposure to the living patients’ blood (66.7% vs 34.5%;χ^(2)= 6.40,P < 0.05), with anRR of 1.93 (95%CI: 1.11-3.37). The mortality risk factors were a long interval from onset to diagnosis [odds ratio (OR)= 1.385), 95%CI: 1.083-1.772,P= 0.009) and advanced age (OR: 1.095, 95%CI: 1.031-1.163,P= 0.01).Conclusions: The SFTS clusters showed a high mortality rate and resulted in a high SAR. Contact with a bleeding corpse was associated with a higher infection risk, compared with contacting the blood from living patients. It is important to promote early detection and appropriate case management of patients with SFTS,

关键词： Severe fever with thrombocytopenia syndrome Cluster Human-to-human transmission Transmission risk Secondary attack rate Blood contact Relative risk Epidemiological characteristics Mortality China

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2024年8月中国需关注的突发公共卫生事件风险评估

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疾病监测 2024年第8期39卷 957-959页

作者：杨康郑灿军陈秋兰刘凤凤王霄晔任婧寰施国庆向妮娟涂文校张彦平亳州市疾病预防控制中心安徽亳州236800 中国疾病预防控制中心应急中心传染病溯源预警与智能决策全国重点实验室北京102206 中国疾病预防控制中心传染病处传染病溯源预警与智能决策全国重点实验室北京102206

目的评估2024年8月在我国(不含香港、澳门特别行政区和台湾省,下同)发生或者可能由境外输入的突发公共卫生事件风险。方法根据国内外突发公共卫生事件报告及重点传染病监测等各种资料和部门通报信息,采用专家会商法,并通过视频会议形... 详细信息

目的评估2024年8月在我国(不含香港、澳门特别行政区和台湾省,下同)发生或者可能由境外输入的突发公共卫生事件风险。方法根据国内外突发公共卫生事件报告及重点传染病监测等各种资料和部门通报信息,采用专家会商法,并通过视频会议形式邀请各省(自治区、直辖市)疾病预防控制中心专家参与评估。结果近期我国境内新型冠状病毒感染疫情呈上升趋势,预计8月境内疫情将达到近期峰值,登革热疫情已进入高峰季节,散发霍乱病例仍可能发生,食物中毒、高温中暑、洪涝灾区水源性、食源性和媒介传染病风险增加。结论对新型冠状病毒感染、登革热、霍乱、食物中毒、高温中暑、洪涝灾害相关传染病予以关注。

关键词：突发公共卫生事件传染病疫情风险评估

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