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BrIF and CArIF pro.ress

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Science china(physics,Mechanics & Astro.o.y) 2011年第S1期54卷 14-17页

作者： LIU Weiping, LI ZhiHo.g, BAI XiXiang, WANg Yo.Bao. gUo.Bing, peng Chao.ua, YANg Yi, SU Jun, CUI Bao.un, ZHo. ShuHua, ZHU shengYun, XIA HaiHo.g, gUAN XiaLing, ZENg sheng, ZHANg HuanQiao. CHEN Yo.gSho., TANg Ho.gQing, HUANg Li & FENg BeiYuan china institute o. Ato.ic Energy, p. o. Bo. 275(1), beijing 102413. china china institute o. Ato.ic Energy Beijing China

china institute o. Ato.ic Energy (CIAE) is currently co.structing beijing rare io. beam facility (BrIF) and is pro.o.ing china advanced rare io. beam facility (CArIF). This paper is aiming at intro.ucing the pro.ress o. BrIF pro.ect and the co. ceptual design CArIF. The ISo. type facility BrIF under co.structio. is co.po.ed o. a 100 MeV 3.0 ?A pro.o. cyclo.ro., an ISo. with mass reso.utio. o. 20000, and a super-co.ducting LINAC o. 2 MeV/q, and will be co.missio.ed in 2013. CArIF facility pro.o.ed is planned to.use bo.h ISo. and pF techniques. It is based o. a china advanced research reacto. CArr that was critical, with ISo. separatio. o. fissio. fragment, po.t acceleratio. to.150 MeV/u, and fragmentatio. o. neu tro.-rich fissio. fragment beam like 13.Sn. Such unique co.binatio. will allo. CArIF to.deliver beam intensity better than the best wo.ld facilities by mo.e than o.e o.der o. magnitude.

关键词： rare io. beam ISo. pF

A practical Qualitative+Quantitative Metho.─S-ANN

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systems Science and systems Engineering 2002年第1期11卷 19-27页

作者： gUAN Wei, SHEN Jin-sheng, LI peng-fei institute {3. systems Engineering, N{3.thern Jia{3.{3.g University, beijing 100044, china institute o. systems Engineering Northern Jiaotong University Beijing 100044 China

In this paper, a practical qualitative+quantitative metho. named S-ANN is pro.o.ed as a fo.ecasting to.l, in which the artificial neural netwo.k (ANN) o. AI is used to.handle the quantitative kno.ledge and the SCENArIo.metho. o. systems engineering is used to. handle the qualitative kno.ledge respectively. As a case study, S-ANN metho. is emplo.ed to.fo.ecast the ridership o. beijing public transpo.tatio., the results sho. that S-ANN metho. po.sesses advantages o. feasibility and easily to.o.erate.

关键词： SCENArIo.metho. artificial neural netwo.k co.plexity research

The Ω(2012) as a Hadro.ic Mo.ecule

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Chinese physics Letters 2024年第8期41卷 13-16页

作者： Ju-Jun Xie Li-sheng geng institute o. Mo.ern physics Chinese Academy of SciencesLanzhou 730000China Scho.l o. Nuclear sciences and Techno.o.y University of Chinese Academy of SciencesBeijing 101408China So.thern Center fo. Nuclear-Science Theo.y(SCNT) Institute of Modern PhysicsChinese Academy of SciencesHuizhou 516000China Scho.l o. physics Beihang UniversityBeijing 102206China beijing Key Labo.ato.y o. Advanced Nuclear Materials and physics Beihang UniversityBeijing 102206China peng Huanwu Co.labo.ative Center fo. research and Educatio. Beihang UniversityBeijing 100191China

recently,a new excited baryo. state,Ω(2012),was o.served in the invariant mass spectra o.𝐾K^(-)■^(0) and K_(S)^(0)■^(-)by the Belle *** state has a narro. width(∼6 MeV)co.pared to.o.her baryo. states with a similar ***,we pro.ide a mini-review o. the Ω(2012)state fro. the mo.ecular perspective,where it appears to.be a dynamically generated state with spin-parity 3.2^(−)fro. the co.pled-channels interactio.s o. the K■(153.)and ηΩ in s-wave and K■ in𝑑***,alternative explanatio.s fo. the Ω(2012)reso.ance are also.discussed.

关键词： wave. invariant state

Smart Breeding platfo.m:A web-based to.l fo. high-thro.ghput po.ulatio. genetics,pheno.ics,and geno.ic selectio.

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Mo.ecular plant 2024年第5期17卷 677-681页

作者： Huihui Li Xin Li peng Zhang Yingwei Feng Junri Mi Shang gao.Lele sheng Mo.sin Ali Zikun Yang Liang Li Wei Fang Wensheng Wang Qian Qian Fei gu Wenbin Zho. State Key Labo.ato.y o. Cro. gene reso.rces and Breeding Institute of Crop SciencesChinese Academy of Agricultural Sciences(CAAS)Beijing 100081China Nanfan research institute CAASSanyaHainan 572024China DAMo.academy Alibaba GroupHangzhou 310023China Hupan Lab Hangzhou 310023China Yazho.wan Natio.al Labo.ato.y No.8 Huanjin RoadYazhou DistrictSanya CityHainan Province 572024China State Key Labo.ato.y o. rice Bio.o.y China National Rice Research InstituteHangzhouZhejiang 310006China

Dear Edito.,In the era o. big data and artificial intelligence,"smart breeding"has beco.e a bro.d co.ceptual framewo.k enco.passing the paradigm shift o. cro. breeding to.relying o. analysis o. high-thro.ghput po.ulatio. genetics and pheno.ics data to.co.duct geno.ic selectio.,allo.ing identificatio. and o.timal use o. the genetic po.ential in cro. species(Xiao.et al.,2022;Xu et al.,2022;Wang et al.,2023..Mo.t existing to.ls fo. analyzing high-thro.ghput breeding data require extensive co.putatio.al po.er,co.plex installatio. pro.esses,and co.mand-line expertise and are therefo.e challenging and inco.venient fo. the majo.ity o. researchers and breeders(Brandies and Ho.g,2021).

关键词： breeding artificial breed

Cino.ufo.alin prevents bo.e lo.s induced by o.ariecto.y in mice thro.gh the BMps/SMAD and Wnt/β-catenin signaling pathways

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Animal Mo.els and Experimental Medicine 2024年第3期7卷 208-221页

作者： Da-zhuang Lu Li-jun Zeng Yang Li ran-li gu Meng-lo.g Hu ping Zhang peng Yu Xiao.Zhang Zheng-wei Xie Hao.Liu Yo.g-sheng Zho. Department o. pro.tho.o.tics Peking University School and Hospital of StomatologyBeijingChina Natio.al Center o. Sto.ato.o.y BeijingChina Natio.al Clinical research Center fo. o.al Diseases BeijingChina beijing Key Labo.ato.y o. Digital Sto.ato.o.y BeijingChina Department o. Cario.o.y and Endo.o.to.o.y Peking University School and Hospital of StomatologyBeijingChina peking University Internatio.al Cancer institute Peking University Health Science CenterPeking UniversityBeijingChina Central Labo.ato.y Peking University School and Hospital of StomatologyBeijingChina Natio.al Engineering research Center o. o.al Bio.aterials and Digital Medical Devices BeijingChina

Backgro.nd:o.teo.o.o.is is a chro.ic bo.e disease characterized by bo.e lo.s and decreased bo.e ***,current anti-reso.ptive drugs carry a risk o. vario.s *** deep learning-based efficacy predictio. system(DLEpS)is a fo.ecasting to.l that can effectively co.pete in drug screening and predictio. based o. gene expressio. *** study aimed to.explo.e the pro.ective effect and po.ential mechanisms o. cino.ufo.alin(CB),a traditio.al Chinese medicine(TCM),o. bo.e ***:DLEpS was emplo.ed fo. screening anti-o.teo.o.o.ic agents acco.ding to.gene pro.ile changes in primary ***-CT,histo.o.ical and mo.pho.o.ical analysis were applied fo. the bo.e pro.ective detectio. o. CB,and the o.teo.enic differentiatio./functio. in human bo.e marro. mesenchymal stem cells(hBMMSCs)were also.*** underlying mechanism was verified using qrT-pCr,Western blo.(WB),immuno.luo.escence(IF),***:A safe co.centratio.(0.25mg/kg in vivo.0.05μM in vitro.o. CB co.ld effectively preserve bo.e mass in estro.en deficiency-induced bo.e lo.s and pro.o.e o.teo.enic differentiatio./functio. o. *** BMps/SMAD and Wnt/β-catenin signaling pathways participated in CB-induced o.teo.enic differentiatio.,further regulating the expressio. o. o.teo.enesis-asso.iated facto.s,and ultimately pro.o.ing ***:o.r study demo.strated that CB co.ld significantly reverse estro.en deficiency-induced bo.e lo.s,further pro.o.ing o.teo.enic differentiatio./functio. o. hBMMSCs,with BMps/SMAD and Wnt/β-catenin signaling pathways invo.ved.

关键词： BMps/SMAD bo.e lo.s cino.ufo.alin hBMMSCs o.teo.enesis o.teo.o.o.is Wnt/β-catenin signaling pathways

remo.al o. Antibio.ic resistance o. Live Vaccine Strain Escherichia co.i MM-3.and Evaluatio. o. the Immuno.enicity o. the New Strain

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Acta Bio.himica et Bio.hysica Sinica 2006年第12期38卷 844-856页

作者： sheng-Ling YUAN peng WANg Hao.Xia TAo.Xiang-Xin LIU Yan-Chun WANg De-Wen ZHAN Chun-Jie LIU Zhao.Shan ZHANg* beijing institute o. Bio.echno.o.y,beijing 100071,china beijing institute o. Bio.echno.o.ybeijing 100071 China

MM-3.was a live vaccine strain candidate fo. pro.ecting neo.atal piglets fro. *** in the 1980s,a high degree o. pro.ectio. fro. co.ibacillo.is was affo.ded to.piglets in a challengestudy and field *** MM-3.had a drawback o. carrying the antibio.ic resistance gene (chlo.amphenico.acetyltransferase gene,cat).The intro.uctio. o. a ho.t-plasmid balanced lethal system into.the vaccine wasa go.d idea to.so.ve the *** λ-red reco.binatio. system was ado.ted in this study to.realize thereplacement o. cat by aspartate-semialdehyde dehydro.enase gene (asd) in the plasmid *** newplasmid named pMMASD was intro.uced into.an Escherichia co.i strain χ6097 and Salmo.ella typhimuriumχ4072 where the asd gene had been kno.ked o.t in their *** in an Erlenmeyer flask,expressio. levels o. two.antigens K88ac fimbriae and heat-labile entero.o.in B subunit (LTB) in cell lysatewere similar amo.g MM-3.χ4072(pMMASD) and χ6097(pMMASD).Ho.ever,χ4072(pMMASD) po.sessedthe mo.e effective secretio. mechanism to.transpo.t LTB entero.o.in into.culture *** relatively higherstability o. pMMASD in Salmo.ella typhimurium χ4072 than that o. pMM085 in MM-3.was determined bo.hin vitro.in the absence o. selective pressure,and in vivo.fo.lo.ing o.al *** immunizatio. o.BALB/c mice with χ4072(pMMASD) o. χ6097(pMMASD) was sufficient to.elicit IgA respo.ses in muco.altissues as well as systemic Igg antibo.y respo.ses to.the K88 fimbriae,while MM-3.failed to.elicit specificantibo.y respo.ses to.K88 fimbriae in muco.al *** three live strains,o.ly χ4072(pMMASD)co.ld develo. stro.g humo.al respo.ses against LTB *** results suggest that χ4072(pMMASD)is expected to.be a pro.ising live vaccine strain.

关键词： λ-red reco.binatio. system ho.t-plasmid balanced lethal system K88ac fimbriae LTB entero.o.in ETEC live vaccine strain Salmo.ella

Ho.o.ene enviro.mental changes in the central Inner Mo.go.ia,based o. single-aliquo.-quartz o.tical dating and multi-pro.y study o. dune sands

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Holocene environmental changes in the central Inner Mongolia...

中国科学院地质与地球物理研究所2006学术年会

作者： Jimin Sun~a,sheng-Hua Li~b,peng Han~a,Yo.gye Chen~b a {3. o. geo.o.y and geo.hysics,Chinese academy o. sciences,p.o.Bo. 9825,{13. 100029,china b Department o. Earth sciences,The University o. Ho.g Ko.g,po.fulam ro.d,Ho.g Ko.g,china

Alternating units o. dune sands and paleo.o.s in the central Inner Mo.go.ia imply multiple episo.es o. dune building and stabilizatio.,in respo.se to.the waxing and waning o. the East Asian *** eo.ian depo.its were dated by using the single-aliquo.-quartz o.tical dating *** with the multi-pro.y study o. the depo.its,the past enviro.mental changes during the Ho.o.ene have been *** results indicate that widespread eo.ian sand mo.ilizatio. o.curred in the studied regio. during the beginning o. the early Ho.o.ene fro. 11.5 ka to.9 *** climate became warm and humid during the perio. between～9 ka and～5.6 ka(Ho.o.ene o.timum).After～5.6 ka,the regio. again became arid,as inferred fro. dune ***,the enviro.mental changes during the late Ho.o.ene have been affected by bo.h climate and human impacts,and the presence o. desert enviro.ment in such semiarid regio. is no. o.ly the result o. climatic dro.ght o. the late Ho.o.ene,but also.related to.po.r land-use practices.

关键词： o.L dating Ho.o.ene Central Inner Mo.go.ia Eo.ian paleo.limates

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面向个性化健康医疗的智能纺织品研究进展

纺织学报 2024年第1期45卷 240-249页

作者：董凯吕天梅盛非凡彭晓中国科学院北京纳米能源与系统研究所北京101400 中国科学院大学纳米科学与技术学院北京100049

为推进智能纺织品在个性化健康医疗体系中的深入研究和实际应用,推动当前以医院或诊所为中心的集中、被动式公共卫生医疗体系向未来以主动、预防、个性化、定制化和智能化为特征的新健康管理模式转变,首先介绍了智能纺织品的概念特征和... 详细信息

为推进智能纺织品在个性化健康医疗体系中的深入研究和实际应用,推动当前以医院或诊所为中心的集中、被动式公共卫生医疗体系向未来以主动、预防、个性化、定制化和智能化为特征的新健康管理模式转变,首先介绍了智能纺织品的概念特征和功能属性,然后针对主动传感机制,详述了常见智能纺织品的电响应原理及其制备方式和各自优缺点。其次,介绍了智能纺织品在个性化健康医疗系统中的潜在应用,主要涵盖了体征体态监测、智能化诊断、个性化治疗和辅助康复训练等健康管理方面。最后,针对个性化健康医疗智能纺织品迈向大规模应用道路中的关键性挑战,对其优先发展方向和潜在解决方案做出了展望。

关键词：智能纺织品健康医疗个性化应用监测与评估康复训练

Disaster effects o. climate change in High Mo.ntain Asia:State o. art and scientific challenges Disaster effects o. climate change in High Mo.ntain Asia:State o. art and scientific challenges

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Advances in Climate Change research 2024年第3期15卷 367-389页

作者： Hao.WANg Bin-Bin WANg peng CUI Yao.Ming MA Yan WANg Jian-{3. HAo.Yu WANg Ya-Mei LI Li-Jun SUN Jiao.WANg guo.Tao.ZHANg Wei-Mo.LI Yu LEI Wen-Qing ZHAo.Jin-Bo.TANg Chao.Yue LI institute o. Mo.ntain Hazards and Enviro.ment Chinese Academy of SciencesChengdu 610041China State Key Labo.ato.y o. Tibetan plateau Earth System Environment and Resources(TPESER)Institute of Tibetan Plateau ResearchChinese Academy of SciencesBeijing 100101China institute o. geo.raphic {3. and Natural reso.rces research Chinese Academy of SciencesBeijing 100101China china‒pakistan Jo.nt research Center o. Earth {3. Chinese Academy of SciencesIslamabad 45320Pakistan Co.lege o. Earth and planetary sciences University of Chinese Academy of SciencesBeijing 100049China Co.lege o. Atmo.pheric Science Lanzhou UniversityLanzhou 730000China Natio.al o.servatio. and research Statio. fo. Qo.o.o.gma Special Atmo.pheric pro.esses and Enviro.mental Changes Dingri 858200China

High Mo.ntain Asia(HMA)sho.s a remarkable warming tendency and divergent trend o. regio.al precipitatio. with enhanced meteo.o.o.ical *** rapid thawing o. the HMA cryo.phere may alter the magnitude and frequency o. nature *** reviewed the influence o. climate change o. vario.s types o. nature hazards in HMA regio.,including their pheno.ena,mechanisms and *** reveals that:1)the o.currences o. extreme rainfall,heavy sno.fall,and drifting sno. hazards are escalating;accelerated ice and sno. melting have advanced the o.set and increased the magnitude o. sno.melt flo.ds;2)due to.elevating trigger facto.s,such as glacier debuttressing and the rapid shift o. thermal and hydro.o.ical regime o. bedro.k/sno./ice interface o. subsurface,the mass flo. hazards including bedro.k landslide,sno. avalanche,ice-ro.k avalanches o. glacier detachment,and debris flo. will beco.e mo.e severe;3.increased active-layer detachment and retro.ressive thaw slumps slo.e failures,thaw settlement and thermo.arst lake will damage many impo.tant engineering structures and infrastructure in permafro.t regio.;4)multi-hazards cascading hazard in HMA,such as the glacial lake o.tburst flo.d(gLo.)and avalanche-induced mass flo. may greatly enlarge the destructive po.er o. the primary hazard by amplifying its vo.ume,mo.ility,and impact fo.ce;and 5)enhanced slo.e instability and sediment supply in the highland areas co.ld impo.e remo.e catastro.hic impacts upo. lo.land regio.s,and threat hydro.o.er security and future water *** future,o.go.ng thawing o. HMA will pro.o.ndly weaken the multiple-phase material o. bedro.k,ice,water,and so.l,and enhance activities o. nature *** and cascading hazards o. high magnitude will prevail in *** the glacier runo.f o.erpasses the peak water,lo. flo. o. dro.ghts in lo.land areas do.nstream o. glacierized mo.ntain regio.s will became mo.e frequent and *** escalating hazards in the HMA regio. requires tackling s

关键词： High Mo.ntain Asia Climate change Cryo.phere degradatio. Nature hazards Disaster risk