检索结果-南通市图书馆

Inhibitory gamma-aminobutyric acidergic neurons in the anterior cingulate cortex participate in the comorbidity of pain and emotion

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第10期20卷 2838-2854页

作者： Lu Guan Mengting qiu Na Li Zhengxiang Zhou Ru Ye Liyan Zhong Yashuang Xu Junhui ren Yi Liang Xiaomei Shao Jianqiao Fang Junfan Fang Junying Du Department of Neurobiology and Acupuncture Research Third School of Clinical MedicineZhejiang Chinese Medical UniversityHangzhouZhejiang ProvinceChina Key Laboratory for Research of Acupuncture Treatment and Transformation of Emotional Diseases Third School of Clinical MedicineZhejiang Chinese Medical UniversityHangzhouZhejiang ProvinceChina Fuchun Community Health Service Center of Fuyang District HangzhouZhejiang ProvinceChina

Pain is often comorbid with emotional disorders such as anxiety and *** of the anterior cingulate cortex has been implicated in pain and pain-related negative emotions that arise from impairments in inhibitory gamma-aminobutyric acid *** review primarily aims to outline the main circuitry(including the input and output connectivity)of the anterior cingulate cortex and classification and functions of different gamma-aminobutyric acidergic neurons;it also describes the neurotransmitters/neuromodulators affecting these neurons,their intercommunication with other neurons,and their importance in mental comorbidities associated with chronic pain *** understanding on their role in pain-related mental comorbidities may facilitate the development of more effective treatments for these ***,the mechanisms that regulate gamma-aminobutyric acidergic systems remain *** is also unclear as to whether the mechanisms are presynaptic or *** exploration of the complexities of this system may reveal new pathways for research and drug development.

关键词： anterior cingulate cortex anxiety chronic pain circuit communication comorbidity depression gamma-aminobutyric acidergic neurons parvalbumin neurons synaptic transmission

Underground laboratories · Deep underground observation ·Scientific questions—Insights from observations of multi-physic fields in deep underground labs

在线全文

学校读者我要写书评

暂无评论

Science China Earth Sciences 2025年

作者： Huiqi ren Yun WANG Chang CHEN Guangyu FU Longqing qiu Lianghui GUO Chengliang XIE Yongsheng HE Heping SUN Jiwen TENG Institute of Defense Engineering Academy of Military Sciences State Kay Laboratory of Geological Processes and Mineral Resources Key Laboratory of Intraplate Volcanoes and Earthquakes Ministry of Education China University of Geosciences (Beijing) Shanghai Institute of Microsystem and Information Technology Chinese Academy of Sciences Innovation Academy for Precision Measurement Science and Technology Chinese Academy of Sciences Institute of Geology and Geophysics Chinese Academy of Sciences

This paper presents a comprehensive review on recent development and research conducted in domestic and international underground laboratories. We first introduce the differences in three environments—surface, mountain tunnel cavities and underground coal mine tunnels—by examining cosmic ray background, ambient noises related to gravity and seismic measurement, and electromagnetic noises in magnetic and magnetotelluric measurements. We highlight potential misuse of the term Underground Lab or Deep Underground Lab when describing observations in different physical fields. We introduce unique features of underground coal mine tunnels in China, such as large spaces, ultra-quiet conditions, and ultra-clean environments. When comparing with mountain tunnel cavities and borehole observations, coal mine tunnel observations have superior long-term stability and high precision. Through observations and comparisons of multi-physic fields at surface and the deep underground, we find that the higher SNR seismic observations conducted in deep underground tunnels in coal mines are beneficial to improve velocity tomography of the solid earth. The gravity observation with a Superconducting Quantum Interference Device(SQUID) makes it possibly to capture slow earthquake, which has not been observed previously in the Chinese mainland. SQUID magnetic observations can detect fluctuations as weak as femto-Tesla(fT), enabling us to explore the attenuation of Schumann Resonance down to the solid Earth. This opens opportunities to investigate the connections between the Earth's magnetic field and the interactions within the human brain and heart. To improve the precision of quantum measurement,we should consider the possible effects of weak magnetic disturbances in deep underground environments. Finally, we discuss the importance of deep underground laboratories, observing facilities and techniques deployed in these laboratories, and their possible connection with respect to “deep space” an

关键词：

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

栗山天牛提取物主要营养成分分析与评价

北华大学学报（自然科学版） 2011年第3期12卷 326-329页

作者：王聪慧邱仁扬李敏任炳忠东北师范大学生命科学学院

采用现代分析技术对栗山天牛提取物的主要营养成分进行了分析.结果显示：栗山天牛提取物的蛋白质、氨基酸、糖类质量分数分别为37.28%、37.25%、8.61%;含有7种人体必需氨基酸,其必需氨基酸占总氨基酸的40.97%,必需氨基酸与非必需氨基酸... 详细信息

采用现代分析技术对栗山天牛提取物的主要营养成分进行了分析.结果显示：栗山天牛提取物的蛋白质、氨基酸、糖类质量分数分别为37.28%、37.25%、8.61%;含有7种人体必需氨基酸,其必需氨基酸占总氨基酸的40.97%,必需氨基酸与非必需氨基酸的比值为0.6939,第一限制性氨基酸为含硫氨基酸,即蛋氨酸和胱氨酸;还含有Ca、Mg、Fe、Mn、Zn、Cu、Mo、N i、Se、Cr等多种矿物质与微量元素.

关键词：栗山天牛营养成分食用昆虫

Antibacterial copper-bearing titanium alloy prepared by laser powder b e d fusion for superior mechanical performance

在线全文

学校读者我要写书评

暂无评论

Journal of Materials Science & Technology 2023年第1期132卷 100-109页

作者： Huan Liu Hai Wang Ling ren Dong qiu Ke yang School of Materials Science and Engineering University of Science and Technology of ChinaShenyang 110016China Shi-changxu Innovation Center for Advanced Materials Institute of Metal ResearchChinese Academy of SciencesShenyang 110016China Centre for Additive Manufacturing School of EngineeringRMIT UniversityMelbourneVictoriaAustralia Binzhou Institute of Technology Weiqiao-UCAS Science and Technology ParkBinzhouShandong Province256606China Shandong Key Laboratory of Advanced Aluminium Materials and Technology Weiqiao-UCAS Science and Technology ParkBinzhouShandong Province256606China

Copper element was added in pure titanium to produce a new biomedical titanium-copper alloy by laser powder bed fusion(LPBF).Addition of copper can eliminate the mismatch of high strength but poor duc-tility problem caused by lathα’martensite,which is the usual microstructure of nearαtitanium alloy fabricated by *** of by the usual trade-offrelationship between strength and ductility,which is a long-standing challenge for martensitic titanium alloys,in this study,we proposed a boundary engineer-ing strategy and aim to synergistically enhance the strength and ductility of martensitic titanium alloy fabricated by *** is hypothesized that whilst both low-angle and high-angle grain boundaries are beneficial to the strength,high-angle grain boundary can simultaneously improve the ductility of *** test this strategy,a Ti-5Cu(wt.%)alloy is selected to compare against pure titanium and Ti-6Al-4V at the same laser processing ***,TEM and XRD analysis show that the as-fabricated LPBF Ti-5Cu alloy is comprised of partially tempered martensite with extraordinarily high number density of both high-angle and low-angle grain boundaries as well as low dislocation *** microstructure enables a high tensile strength of 940-1020 MPa,which is at a similar level as LPBF Ti-6Al-4V,and an excellent elongation of 13%-16%,twice as much as that of LPBF *** mechanism of microstruc-ture refinement in LPBF Ti-5Cu at different levels from prior-βgrains,martensitic packets,blocks to laths is also discussed.

关键词： Titanium alloy Laser powder bed fusion Boundary engineering Martensite Mechanical properties

Bioactive glass sol as a dual function additive for chitosan-alginate hybrid scaffold

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Chemical Letters 2018年第3期29卷 395-398页

作者： Huihui ren yang Cui Ailing Li Dong qiu Beijing National Laboratory for Molecular Sciences State Key Laboratory of Polymer Physics and Chemistry CAS Research/Education Center for Excellence in Molecular Sciences Institute of Chemistry Chinese Academy of Sciences Beijing 100190 China University of Chinese Academy of Sciences Beijing 100190 China

Bioactive glass-chitosan-alginate hybrid scaffolds （BG-C-A scaffolds） were fabricated using BG sol as a dual function additive, which behaves as both bioactive inorganic phase to confer the bioactivity and cross-linker to improve the structural stability and mechanical properties. The microstructure, physicochemical and mechanical properties, in vitro bioactivity and cellular biocompatibility of the scaffolds were investigated. The results indicated that BG component was successfully incorporated into the BG-C-A scaffolds through a facile BG sol-immersing method and the original interconnected microstructure could be well preserved. The obtained BG-C-A scaffolds showed improved mechanical properties and structural stability as compared to C-A scaffolds. At the same time, they presented excellent in vitro bioactivity and cellular compatibility. All these results demonstrated that these BG-C-A scaffolds have promising potential for tissue engineering.

关键词： Bioactive glass sol Chitosan Alginate Dual function additive Bioactivity

High-entropy design boosts dielectric energy storage

在线全文

学校读者我要写书评

暂无评论

Rare Metals 2024年第8期43卷 4013-4015页

作者： qiu-Ying Xia He Zhu Si Lan yang ren Herbert Gleiter Institute of Nanoscience School of Materials Science and EngineeringNanjing University of Science and TechnologyNanjing 210094China Department of Physics City University of Hong KongHong Kong999077China

Dielectric capacitors are vital for advanced electronic and electrical power systems due to their impressive power density and ***,a persistent challenge has been enhancing their energy densities while maintaining high *** in Science,a novel high-entropy design for relaxor ferroelectric materials has been proposed,promising significant improvements in both energy density and efficiency for multilayer dielectric ceramic *** the crucial role of high-entropy design in energy storage materials and devices,this highlight focuses on interpreting the progress and significance of this innovative work.

关键词： ceramic dielectric energy

Molecular Cloning and Bacterial Expression of Germacrene A Synthase cDNA from Crepidiastrum sonchifolium

在线全文

学校读者我要写书评

暂无评论

Chemical Research in Chinese Universities 2006年第5期22卷 606-611页

作者： ren Jie LIU Yan-qiu yang Li NI Rui YOU Song School of Pharmaceutical Engineering Shenyang Pharmaceutical UniversityShenyang 110016 P. R. China

Germacrene A synthase（GAS） catalyzes the biosynthesis of germacrene A, which is a key precursor for sesquiterpone lactones. Cloning of a novel full-length cDNA encoding GAS from the medicinal plant Crepidiastrum sonchifolium（dosignated CsGAS） is reported in this study. The cDNA is 1837 bp long and contains a 1680-bp open reading frame encoding a 559 amino-acid protein. The functional expression of the cDNA in Escherichia coli, as an N-terminal thioredoxin fusion protein, with the pET32a vector yielding a recombinant enzyme. Sequence analysis was used to compare this enzyme with the mechanistically related epi-aristolochene synthase from tobacco, and the effect of possible involvement of a number of amino acids in sesquiterpone synthase on product specificity was also discussed.

关键词： Germacrene A synthase Crepidiastrum sonchifolium Sesquiterpene synthase Expression Fusion protein

Transient aeroelastic responses and flutter analysis of a variable-span wing during the morphing process

在线全文

学校读者我要写书评

暂无评论

Chinese Journal of Aeronautics 2013年第6期26卷 1430-1438页

作者： Huang ren qiu Zhiping Institute of Solid Mechanics Beihang University

To investigate the transient aeroelastic responses and flutter characteristics of a variablespan wing during the morphing process,a novel frst-order state-space aeroelastic model is *** time-varying structural model of the morphing wing is established based on the Euler-Bernoulli beam theory with time-dependent boundary conditions.A nondimensionalization method is used to translate the time-dependent boundary conditions to be *** time-domain aerodynamic forces are calculated by the reduced-order unsteady vortex lattice *** morphing parameters,i.e.,wing span length and morphing speed,are of particular interest for understanding the fundamental aeroelastic behavior of variable-span wings.A test case is proposed and numerical results indicate that the flutter characteristics are sensitive to both of the two morphing *** could be noticed that the aeroelastic characteristics during the wing extracting process are more serious than those during the extending process at the same morphing speed by transient aeroelastic response *** addition,a faster morphing process can get better aeroelastic performance while the mechanism comlexity will arise.

关键词： Galerkin methods Morphing aircraft Time-varying systems Transient aeroelastic Unsteady vortex lattice method Variable-span wing

基于光谱技术的典型互花米草入侵湿地土壤属性预测研究

在线全文

学校读者我要写书评

暂无评论

光谱学与光谱分析 2025年第1期45卷 197-203页

作者：陈旭曹思珩杨仁敏陈秋宇李建国徐璐 4 江苏师范大学地理测绘与城乡规划学院地理信息科学系江苏徐州221116

为了高效监测互花米草入侵海岸带湿地生态系统的土壤属性变化,选取江苏省盐城湿地珍禽国家级自然保护区的一处典型互花米草入侵湿地作为研究区,利用随机分层采样方法选取15个样点,在3个深度(0~30、30~60、60~100 cm)共采集45个土壤样品... 详细信息

为了高效监测互花米草入侵海岸带湿地生态系统的土壤属性变化,选取江苏省盐城湿地珍禽国家级自然保护区的一处典型互花米草入侵湿地作为研究区,利用随机分层采样方法选取15个样点,在3个深度(0~30、30~60、60~100 cm)共采集45个土壤样品,测定了土壤可见光-近红外反射光谱和10种土壤理化属性,研究了偏最小二乘和随机森林两种方法的预测能力,分析了不同光谱变换形式对预测精度的影响,探讨了入侵年限和土壤深度作为辅助预测变量的潜力。结果表明:(1)可见光-近红外光谱技术可以较好地预测有机碳、无机碳、全氮、含水量、pH、容重、盐分和黏粒等属性;(2)偏最小二乘回归法比随机森林法更适合监测互花米草入侵湿地的关键土壤理化属性,利用偏最小二乘法对土壤属性建立的预测模型精度(R^(2))在0.341~0.979之间,随机森林方法对土壤属性建立的预测模型精度(R^(2))最高为0.722;(3)基于原始光谱可以获得土壤全氮的最优预测模型(R^(2)为0.769,RMSE为0.091 g·kg^(-1)),而其他土壤属性的最优模型多是基于微分变换或倒数变换建立的模型,微分变换和倒数变换可以有效地提高模型预测精度;(4)模型预测精度在加入入侵年限和土壤深度两个变量后总体上有所提高,其中有机碳、全氮、盐分、pH和容重等属性的预测精度对这两个变量更为敏感,土壤有机碳最优模型的精度(R^(2))从0.794提高到0.806,pH最优模型的精度(R^(2))从0.838提升至0.884,盐分最优模型的精度(R^(2))从0.978提升至0.997。综上所述,可见光-近红外光谱技术在互花米草入侵湿地关键土壤理化属性预测方面具有明显的优越性,通过适当的光谱变换、变量筛选、模型选择等方面可以实现互花米草入侵湿地土壤变化的快速监测。

关键词：互花米草入侵可见光-近红外光谱土壤监测偏最小二乘法随机森林光谱变换