检索结果-南通市图书馆

Posterior scleral reinforcement combined with vitrectomy for myopic foveoschisis

International Journal of Ophthalmology(English edition) 2016年第2期9卷 258-261页

作者： Xiu-Juan li Xiao-Peng Yang qiu-ming li Yu-Ying Wang Jing Wang Xiao-Bei Lyu Heng Jia Department of Ophthalmology the First Affiliated Hospital of Zhengzhou University Department of Medical Equipment the First Affiliated Hospital of Zhengzhou University

AIM： To investigate the effects of posterior scleral reinforcement （PSR） combined with vitrectomy for myopic foveoschisis. ~ METHODS： Thirty-nine highly myopic eyes of 39 patients with myopic foveoschisis underwent PSR combined with vitrectomy. Best corrected visual acuity （BCVA）, refraction error, and the foveal thickness by optical coherence tomography （OCT） were recorded before and after the surgery, and complications were noted. RESULTS： The follow-up period was 12mo, and the main focus was on the results of the 12-month follow-up visit. The mean preoperative BCVA was 0.96±0.43 IogMAR. At the final follow-up visit, the mean BCVA was 0.46± 0.28 IogMAR, which significantly improved compared with the preoperative one （P =0.003）. The BCVA improved in 33 eyes （84.62%）, and unchanged in 6 eyes （15.38%）. At the end of follow-up, the mean refractive error was -15.13 ±2.55 D, and the improvement was significantly compared with the preoperative one （-17.53±4.51 D）（P= 0.002）. Twelve months after surgery, OCT showed complete resolution of the myopic foveoschisis and a reattachment of the fovea in 37 eyes （94.87%） and partial resolution in the remained two eyes （5.13%）. The foveal thickness was obviously reduced at 12-month follow-up visit （196.45±36.35um） compared with the preoperative one （389,32±75.56um）（P=0.002）. There were no serious complications during the 12mo follow-up period. CONCLUSION： PSR combined with vitrectomy is a safe and effective procedure for myopic foveoschisis with both visual and anatomic improvement.

关键词： high myopia myopic foveoschisis posteriorscleral reinforcement vitrectomy

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Posterior scleral reinforcement for the treatment of pathological myopia

引用

International Journal of Ophthalmology(English edition) 2016年第4期9卷 580-584页

作者： Xiu-Juan li Xiao-Peng Yang qiu-ming li Yu-Ying Wang Yuan Wang Xiao-Bei Lyu Heng Jia Department of Ophthalmology the First Affiliated Hospital of Zhengzhou University Department of Medical Equipment the First Affiliated Hospital of Zhengzhou University Department of Ophthalmology Zhengzhou Central Hospital Affiliated to Zhengzhou University

AIM： To investigate the effects of posterior scleral reinforcement（PSR） in the treatment of pathological myopia.·METHODS： The study included 52 eyes in 43 patients with pathological myopia who underwent PSR（PSR group）, and 52 eyes in 36 age- and myopia-matched patients who did not undergo such treatment as control group. Axial length, refraction error, best corrected visual acuity（BCVA）, and macular scans by optical coherence tomography（OCT） were recorded at baseline, 6mo, 1, 3and 5y after the surgery, and the complications were noted.·RESULTS： There were no statistical differences in axial length, refractive error, or BCVA between the PSR group and the control group at baseline. At the end of the follow-up, the mean axial length was 29.79 ±1.26 mm in the PSR group, which was significantly shorter than that in the control group（30.78±1.30 mm）（P 〈0.01）, and the mean refractive error was-16.86 ±2.53 D in the PSR group, which was significantly lower than that in the control group（-19.18 ±2.12 D）（P 〈0.01）. A statistically significant difference in BCVA was found between the PSR group（0.51 ±0.25 log MAR） and the control group（0.62±0.26 log MAR） at the postoperative 5-year follow-up（P 〈0.01）. There were no serious complications during the 5-year follow-up period.·CONCLUSION： PSR can prevent axial elongation and myopia progression in eyes with pathological myopia.

关键词： pathological myopia posterior scleral reinforcement axial length

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Flanibizumab Plus Combined Surgery for Treatment o Neovascular Glaucoma with Vitreous Hemorrhage

引用

Chinese Medical Journal 2015年第15期128卷 2078-2083页

作者： Xiu-Juan li Xiao-Peng Yang qiu-ming li Yu-Ying Wang Xiao-Bei Lyu Department of Ophthalmology The First Affiliated Hospital of Zhengzhou University Zhengzhou Henan 450052 China Department of Medical Equipment The First Affiliated Hospital of Zhengzhou University Zhengzhou Henan 450052 China

Background：Neovascular glaucoma （NVG） is a refractory *** management of NVG is very difficult,and it is more difficult when combined with vitreous *** aim of this study was to investigate the effects of ranibizumab plus combined surgery for NVG with vitreous ***：A total of 26 eyes of 26 NVG patients with vitreous hemorrhage were recruited in this *** patients aged from 36 to 63 years with a mean age of 51.97 ± 7.60 *** mean intraocular pressure （IOP） was 46.38 ± 5.75 mmHg （1 mmHg =0.133 kPa） while being treated with the maximum medical *** mean best-corrected visual acuities converted to logarithm of the minimum angle of resolution （logMAR BCVA） was 2.62 ± *** the patients underwent intravitreal injection of 0.5 mg （0.05 ml） ranibizumab combined with pars plana vitrectomy （PPV）,pars plana lensectomy （PPL） with a preserved anterior capsule,panretinal photocoagulation （PRP）,and trabeculectomy （intravitreal ranibizumab [IVR] ＋ PPV ＋ PPL ＋ PRP ＋ trabeculectomy）.The IOP and logMAR BCVA were the main outcome measures in this ***：The follow-up period was 12 *** mean postoperative IOPs were 26.38 ± 3.75 mmHg,21.36 ± 3.32 mmHg,1 8.57 ± 3.21 mmHg,and 16.68 ± 2.96 mmHg,respectively at 7 days,1 month,3 months,and 12 months after PPV ＋ PPL ＋ PRP ＋ *** the last follow-up,the mean IOP was significantly lower than the preoperative one （t =6.612,P =0.001）.At 7 days,1 month,3 months,and 12 months after PPV ＋ PPL ＋ PRP ＋ trabeculectomy,the mean logMAR BCVA were 1.30 ± 0.36,1.29 ± 0.37,1.29 ± 0.39,and 1.26 ± 0.29,*** the last follow-up,the mean logMAR BCVA was significantly improved,and the difference was statistically significant compared with preoperative one （t =6.133,P =0.002）.The logMAR BCVA improved in 22 eyes （84.62%）,and remained stable in 4 eyes （15.38%）.The neovascularization in the iris and the angle regressed significantly in all patients 7 days after ranibizumab injection

关键词： Neovascular Glaucoma Panretinal Photocoagulation Pars Plana Vitrectomy Ranibizumab Trabeculectomy

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Attenuation of myocardial apoptosis by alpha-lipoic acid through suppression of mitochondrial oxidative stress to reduce diabetic cardiomyopathy

引用

Chinese Medical Journal 2009年第21期122卷 2580-2586页

作者： li Chun-jun ZHANG qiu-mei li ming-zhen ZHANG Jing-yun YU Pei YU De-min The Ministry of Health Key Laboratory of Hormone and Development Department of Endocrinology Metabolic Disease Hospital of Tianjin Medical University Tianjin 300070 China

Background Cardiac failure is a leading cause of the mortality of diabetic patients. In part this is due to a specific cardiomyopathy, referred to as diabetic cardiomyopathy. Oxidative stress is widely considered to be one of the major factors underlying the pathogenesis of the disease. This study aimed to test whether the antioxidant α-lipoic acid （α-LA） could attenuate mitochondrion-dependent myocardial apoptosis through suppression of mitochondrial oxidative stress to reduce diabetic cardiomyopathy. Methods A rat model of diabetes was induced by a single tail intravenous injection of streptozotocin （STZ） 45 mg/kg. Experimental animals were randomly assigned to 3 groups： normal control （NC）, diabetes （DM） and DM treated with α-LA （α-LA）. The latter group was administered with a-LA （100 mg/kg ip per day）, the remainder received the same volume vehicle. At weeks 4, 8, and 12 after the onset of diabetes, cardiac apoptosis was examined by TUNEL assay. Cardiomyopathy was evaluated by assessment of cardiac structure and function. Oxidative damage was evaluated by the content of malondialdehyde （MDA）, reduced glutathione （GSH） and the activity of manganese superoxide diamutase （Mn-SOD） in the myocardial mitochondria. Expression of caspase-9 and caspase-3 proteins was determined by immunohistochemistry and mitochondrial cytochrome c release was detected by Western blotting Results At 4, 8, and 12 weeks after the onset of diabetes, significant reductions in TUNEL-positive cells, caspase-9,-3 expression, and mitochondrial cytochrome c release were observed in the α-LA group compared to the DM group. In the DM group, the content of MDA in the myocardial mitochondria was significantly increased, and there was a decrease in both the mitochondrial GSH content and the activities of Mn-SOD. They were significantly improved by α-LA treatment. HE staining displayed structural abnormalities in diabetic hearts, while α-LA reversed this structural derangement. The index of cardiac fun

关键词： alpha-lipoic acid myocardial apoptosis mitochondrial oxidative stress diabetic cardiomyopathy

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

添加CeO_2对MoS_2基复合涂层摩擦学性能的影响

引用

中国表面工程 2017年第2期30卷 106-112页

作者：邱明张瑞李迎春周占生河南科技大学机电工程学院河南洛阳471003 河南科技大学机械装备先进制造河南省协同创新中心河南洛阳471003

针对MoS_2基复合涂层耐磨性差和承载能力低的问题,以不同含量(质量分数)的CeO_2作为添加剂,采用喷涂法在GCr15钢表面制备MoS_2基复合涂层。利用摩擦磨损试验机和划痕仪分别研究涂层摩擦磨损性能和结合强度,并借助金相显微镜对涂层磨损... 详细信息

针对MoS_2基复合涂层耐磨性差和承载能力低的问题,以不同含量(质量分数)的CeO_2作为添加剂,采用喷涂法在GCr15钢表面制备MoS_2基复合涂层。利用摩擦磨损试验机和划痕仪分别研究涂层摩擦磨损性能和结合强度,并借助金相显微镜对涂层磨损形貌进行表征。结果表明:添加适量CeO_2可以改善涂层的摩擦磨损性能,其最佳含量为2%,此时摩擦因数和磨损量均最小,分别为0.232和0.011 3 mm^3;同时结合强度从22 N提高到28.29 N。涂层磨损量随载荷的增大而增大;而载荷小于8 N时,涂层的摩擦因数随载荷的增大而减小,当载荷大于8 N时,摩擦因数又有回升趋势。添加稀土后涂层的承载能力有明显提高。未添加稀土时,涂层产生严重剥离,并发生磨粒磨损;添加2%CeO_2后,涂层发生轻微磨粒磨损,耐磨性得到显著提高。

关键词：稀土 MoS2 摩擦磨损涂层磨粒磨损

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Functional reconstruction of ischemic contracture in the lower limb

引用

Chinese Journal of Traumatology 2011年第2期14卷 96-99页

作者： TANG Hao ZHANG Shao-cheng TAN Zhang-yong ZHU Hong-wei ZHANG qiu-lin li ming Department of Orthopedics Changhai Hospital Second Military University Shanghai 200433 China

Objective： To discuss the method of functional reconstruction of ischemic contracture in the lower limb and propose a classification protocol for ischemic contracture in the lower limb based on its severity and prognosis. Methods： Atotal of 42 patients with ischemic contracture in the lower limb were included in this study. According to different types of disturbance and degrees of severity, surgical reconstructions consisting of nerve decompression, tendon lengthening or transfer, intrinsic foot muscle release and sural-tibial nerve anastomosis were performed in every patient. Results： Postoperatively, all patients were able to walk on flat ground. Drop foot was corrected in 10 patients, and 5 patients still felt some difficulty during stair activity. Split Achilles tendon transfer to flexor hallucis longus tendon was performed in 12 patients, and their walking stability was improved. Seven patients accepted ipsilateral suraltibial nerve anastomosis, and sensitivity recovery reached to S2 in 2 patients and S3 in 5 patients. Conclusions： Iscbemic contracture in the lower limb is a devastating complication after lower limb trauma. The prevention of contracture is much more important than the treatment of an established contracture. Split Achilles tendon transfer to flexor hallucis longus tendon and sural-tibial nerve anastomosis, which was initially implemented by us, could improve the functional recovery of ischemic contracture in lower limbs, and thus provides a new alternative for functional reconstruction of ischemic contracture in the lower limb.

关键词： Ischemic contracture Classification Recovery of function

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

煤岩破裂过程表面电位云图软件开发及应用

引用

煤炭学报 2015年第7期40卷 1562-1568页

作者：李保林王恩元李忠辉李楠刘杰邱黎明中国矿业大学煤矿瓦斯与火灾防治教育部重点实验室江苏徐州221116 中国矿业大学安全工程学院江苏徐州221116 中国矿业大学煤炭资源与安全开采国家重点实验室江苏徐州221116 青岛理工大学安全工程系山东青岛266520

针对克里金插值法中理论变异函数拟合精度不稳定及缺乏专用电位云图软件问题,提出了计算理论变异函数模型参数的自动-人工拟合方法,并利用MATLAB开发了煤岩破裂过程表面电位云图软件。对预制45°裂纹岩样进行了单轴压缩实验,利用该软件... 详细信息

针对克里金插值法中理论变异函数拟合精度不稳定及缺乏专用电位云图软件问题,提出了计算理论变异函数模型参数的自动-人工拟合方法,并利用MATLAB开发了煤岩破裂过程表面电位云图软件。对预制45°裂纹岩样进行了单轴压缩实验,利用该软件绘制了岩样变形破裂过程中的表面电位云图,分析了表面电位分布与试样破裂状态的对应关系。研究表明:自动-人工拟合法计算过程稳定,有效提高了克里金插值法的精度;基于开发的电位云图软件绘制的电位云图能够真实反映煤岩体的表面电位分布及变化;岩样表面电位云图可以反映裂纹的扩展方向及岩样破裂状态;在岩样弹性变形阶段后期,表面电位云图反映了岩样裂纹扩展的前兆信息。

关键词：表面电位云图分析克里金插值法拟合方法

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

5′-N-乙基酰胺基腺苷对大鼠脑缺血再灌注氧化损伤和脑组织miR-29b、miR-125b水平的影响

引用

中国临床药理学杂志 2024年第10期40卷 1448-1452页

作者：李泽谭军明秋丽栗延伟新乡医学院第三附属医院神经内科河南新乡453000

目的探究5′-N-乙基酰胺基腺苷(NECA)对大鼠脑缺血再灌注氧化损伤和脑组织中miR-29b、miR-125b水平的影响。方法将SD大鼠随机分为假手术组、模型组、实验组和阳性对照组,每组12只。建模前7 d,实验组腹腔注射1.5 mg·kg^(-1)的NECA;阳性... 详细信息

目的探究5′-N-乙基酰胺基腺苷(NECA)对大鼠脑缺血再灌注氧化损伤和脑组织中miR-29b、miR-125b水平的影响。方法将SD大鼠随机分为假手术组、模型组、实验组和阳性对照组,每组12只。建模前7 d,实验组腹腔注射1.5 mg·kg^(-1)的NECA;阳性对照组腹腔注射2.0 mg·kg^(-1)的尼莫地平;假手术组和模型组均腹腔注射等量0.9%NaCl。4组大鼠每天给药1次,连续给药7 d。除假手术组外,其余3组均用大脑中动脉栓塞方法建立脑缺血再灌注模型。建模成功后,用酶联免疫吸附试验法测定大鼠血清氧化应激指标[谷胱甘肽(GSH)、超氧化物歧化酶(SOD)、过氧化氢酶(CAT)、丙二醛(MDA)]水平,用实时荧光定量聚合酶链反应法检测脑组织中miR-29b、miR-125b的表达水平。结果假手术组、模型组、实验组和阳性对照组的SOD分别为(57.82±6.87)、(10.75±0.24)、(32.24±3.42)和(29.45±4.11)U·mL^(-1),GSH分别为(20.62±3.12)、(9.45±1.92)、(16.78±1.85)和(15.39±2.02)U·mg^(-1),CAT分别为(3.25±0.42)、(0.85±0.11)、(2.18±0.34)和(1.98±0.32)U·L^(-1),MDA分别为(0.42±0.09)、(1.35±0.42)、(0.75±0.06)和(0.72±0.08)nmol·mg^(-1),脑组织中miR-29b表达水平分别为1.02±0.11、0.42±0.02、0.84±0.08和0.87±0.10,miR-125b表达水平分别为1.00±0.11、0.48±0.05、0.75±0.08和0.74±0.07。模型组的上述指标与实验组、阳性对照组和假手术组比较,在统计学上差异均有统计学意义(均P<0.05)。结论NECA可改善脑缺血再灌注大鼠氧化损伤,并增加miR-29b和miR-125b水平。

关键词： 5′-N-乙基酰胺基腺苷脑缺血再灌注氧化损伤脑组织微小RNA-29b 微小RNA-125b

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

聚酯/碳纤维复合材料的自修复性能研究

引用

功能材料 2011年第6期42卷 1004-1007,1011页

作者：倪卓林燕玲王帅林柳丽邱利明深圳大学化学与化工学院广东深圳518060

合成了脲醛树脂/环氧树脂微胶囊,并作为功能材料设计自修复聚酯/碳纤维复合材料。采用力学性能测试,扫描电子显微镜(SEM)和光学显微镜(OM)对微胶囊功能材料和自修复材料进行研究。碳纤维能够提高材料的弹性模量,在材料损伤过程中,控制... 详细信息

合成了脲醛树脂/环氧树脂微胶囊,并作为功能材料设计自修复聚酯/碳纤维复合材料。采用力学性能测试,扫描电子显微镜(SEM)和光学显微镜(OM)对微胶囊功能材料和自修复材料进行研究。碳纤维能够提高材料的弹性模量,在材料损伤过程中,控制裂缝的宽度。微胶囊具有增韧效果和自修复能力。经过拉伸复合材料内部产生裂纹。微胶囊在裂纹前端应力的作用下,囊壁破裂,囊芯流出润湿裂纹表面粘接裂纹,实现材料自修复。裂纹终止的形式包括微胶囊破裂终止、碳纤维阻碍终止和裂纹交叉终止。

关键词：材料物理与化学自修复性能扫描电镜微胶囊微裂纹

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

女性高危型人乳头瘤病毒感染分布情况研究

引用

中国实用妇科与产科杂志 2017年第1期33卷 122-124页

作者：吴云燕裘明利富阳区第一人民医院浙江杭州311400 富阳区妇幼保健院浙江杭州311400

目的探讨浙江省富阳地区女性高危型人乳头瘤病毒(HPV)感染率和基因型分布情况。方法采用荧光PCR法,对2013年4月至2015年11月富阳区第一人民医院和富阳区妇幼保健院妇科就诊的13 447例患者宫颈标本检测世界卫生组织(WHO)确认的13种高危HP... 详细信息

目的探讨浙江省富阳地区女性高危型人乳头瘤病毒(HPV)感染率和基因型分布情况。方法采用荧光PCR法,对2013年4月至2015年11月富阳区第一人民医院和富阳区妇幼保健院妇科就诊的13 447例患者宫颈标本检测世界卫生组织(WHO)确认的13种高危HPV型别,包括HPVl6、18、31、33、35、39、45、51、52、56、58、59和68型。结果高危型HPV基因检测感染率为24.57%(3304/13 447),其中单一基因型感染率为17.97%(2416/13 447),多重亚型混合感染率为6.60%(888/13 447);其中以HPV52、HPV16、HPV58三种亚型最多见,所占比例分别为6.51%、5.87%、4.47%。结论浙江省富阳地区妇科就诊女性患者HPV感染以HPV52、HPV16、HPV58三型较多见,常见感染亚型总体符合亚洲国家分布情况,同时又具有其独特的地区分布特点。

关键词：高危型人乳头瘤病毒感染基因型

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：